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World Journ.l of Gastroen.erology 2025年第2期31卷 128-131页

作者： Grigorios Christodoulidis Sara e Agko Marin. n.Kouliou Kon.tan.in.s e Koumarelas Dimitris Zacharoulis Departmen. of Gen.ral Surgery University Hospital of LarissaLarissa 41110Greece Departmen. of In.en.ive Care Un.t Asklepios Paulinen Clinic WiesbadenWiesbaden 65197Germany Departmen. of emergen.y Medicin. General Hospital of LarissaLarissa 41221Greece Departmen. of Surgery University Hospital of LarissaLarissa 41334Greece

Autoimmun. en.eropathy(AIe)is a rare immun. mediated disorder primarily affectin. children.characterized by chron.c diarrhea,malabsorption.vomitin.,weight loss an. villous *** has also been.observed in.adults presen.in. diagn.stic an. treatmen. challen.es due to its overlap with other gastroin.estin.l disorders such as celiac *** diagn.stic criteria for AIe in.lude small bowel villous atrophy,lack of respon.e to dietary restriction.,presen.e of an.i-en.erocyte an.ibodies,an. predisposition.to autoimmun.ty without severe *** criteria emphasize characteristic histological fin.in.s an. exclusion.of other causes of villous *** is associated with various autoimmun. disorders an. can.presen. with overlappin. features with Celiac disease,in.ludin. villous atrophy but without sign.fican. in.raepithelial *** primarily in.olves immun.suppression.usin. corticosteroids,calcin.urin.in.ibitors,an. an.i-tumor n.crosis factor therapy,alon.side n.tri-tion.l *** the challen.es,un.erstan.in. AIe’s diverse man.fest-ation. an. improvin. diagn.stic criteria are essen.ial for effective man.gemen. an. improved patien. *** research is n.eded to elucidate the pathogen.sis,disease progression.an. lon.-term outcomes of AIe.

关键词： Autoimmun. en.eropathy Diagn.sis Progn.sis Adult autoimmun. en.er-opathy an. challen.es Autoimmun. en.eropathy an. treatmen. Autoimmun. en.eropathy an. diagn.stic criteria Pathophysiology of autoimmun. en.eropathy

efficien. above-ban.-gap light emission.in.german.um

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Chin.se Optics Letters 2009年第4期7卷 271-273页

作者： Ken.eth e.lee eugen. A.Fitzgerald Lion.l C.Kimerlin. Jurgen.Michel Departmen. of Materials Scien.e an. en.in.erin. Microphotonics CenterMassachusetts Institute of Technology

We report an.above-ban.-gap radiative tran.ition.in.the photolumin.scen.e spectra of sin.le crystallin. Ge in.the temperature ran.e of 20-296 K. The temperature-in.epen.en.e of the peak position.at -0.74 eV is remarkably differen. from the behavior of direct an. in.irect gap tran.ition. in.Ge. This tran.ition.is observed in.n.type, p-type, an. in.rin.ic sin.le crystal Ge alike, an. its in.en.ity decreases with the in.rease of temperature with a small activation.en.rgy of 56 meV. Some aspects of the tran.ition.are an.logous to III-V semicon.uctors with dilute n.trogen.dopin., which suggests that the origin.could be related to an.isoelectron.c defect.

关键词： Activation.en.rgy German.um Photolumin.scen.e Semicon.uctor dopin. Sin.le crystals

A n.w Fossil Termite (Isoptera,Stolotermitidae,Stolotermes) from the early Miocen. of Otago,n.w Zealan.

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Acta Geologica Sin.ca(en.lish edition. 2010年第4期84卷 705-709页

作者： Uwe KAULFUSS An.hon. C.HARRIS Daphn. e.lee Departmen. of Geology University of OtagoPO Box 56Dunedin 9054New Zealand Otago Museum PO Box 6202Dunedin 9059New Zealand

The forewin. of a termite from early Miocen. lake sedimen.s in.Otago, southern.n.w Zealan. is figured an. described. It exhibits the gen.ric characters of the damp-wood termite Stolotermes Hagen. but differs from forewin.s of the kn.wn.species in.size an. ven.tion.pattern.an. is described as Stolotermes kupe sp. n.v. S. kupe represen.s the first con.iden. record of fossil Stolotermitidae an. exten.s the fossil record of the family back to the early Miocen.. It also is the first direct eviden.e of fossil Isoptera from n.w Zealan., though silicified termite faecal pellets, referable to Kalotermes braun., have been.previously described. S. kupe in.icates that Stolotermitidae has been.presen. in.the Australasian.region.sin.e at least the early Miocen..

关键词： early Miocen. fossil termite Isoptera Stolotermes n.w species Otago Fouiden.Maar Gon.wan.

Post-operative preven.ion.an. mon.torin. of Crohn.s disease recurren.e

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Gastroen.erology Report 2022年第1期10卷 217-226页

作者： Kate e.lee Sarah Can.rell Bo Shen.Adam S.Faye Departmen. of Medicin. Duke University Medical CenterDurhamNCUSA Duke Un.versity Medical Cen.er Library&Archives Duke University School of MedicineDurhamNCUSA Cen.er for In.lammatory Bowel Diseases NewYork-Presbyterian/Columbia University Irving Medical CenterNew YorkNYUSA Division.of Gastroen.erology NYU Grossman School of MedicineNew YorkNYUSA

Crohn.s disease(CD)an. ulcerative colitis(UC)are relapsin. an. remittin. chron.c in.lammatory diseases of the gastroin.estin.l *** surgery for UC can.provide a cure,surgery for CD is rarely *** the past few decades,research has iden.ified risk factors for postsurgical CD recurren.e,en.blin. patien. risk stratification.to guide mon.torin. an. prophylactic treatmen. to preven. CD recurren.e.A MeDLIn. literature review iden.ified articles regardin. post-operative mon.torin. of CD recurren.e after resection.*** this review,we discuss the eviden.e on.risk factors for postoperative CD recurren.e as well as suggestion. on.post-operative man.gemen..

关键词： post-operative Crohn.s man.gemen. recurren.e biologics

PGLYRP1 protein.as a n.vel mediator of cellular dialogue in.n.uroin.lammation

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n.ural Regen.ration.Research 2025年第7期20卷 1993-1994页

作者： An.p Bhusal Won.Ha lee Kyoun.ho Suk Departmen. of Pharmacology School of MedicineKyungpook National UniversityDaeguRepublic of Korea BK21 Plus Kn. Biomedical Con.ergen.e Program Department of Biomedical ScienceSchool of MedicineKyungpook National UniversityDaeguRepublic of Korea School of Life Scien.es BK21 plus KNU Creative BioResearch GroupKyungpook National UniversityDaeguRepublic of Korea Brain.Scien.e an. en.in.erin. In.titute Kyungpook National UniversityDaeguRepublic of Korea

n.uroin.lammation.has been.iden.ified as a crucial elemen. in.several n.urological disorders. Glial cells play a critical role in.directin. n.uroin.lammation. both in.deleterious an. ben.ficial ways.

关键词： in.lammation con.iderably

Sin.le-cell an. spatial omics:explorin. hypothalamic heterogen.ity

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n.ural Regen.ration.Research 2025年第6期20卷 1525-1540页

作者： Muhammad Jun.id eun.Jeon. lee Su Bin.Lim Departmen. of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Departmen. of Biomedical Scien.es Graduate School of Ajou UniversitySuwonSouth Korea Departmen. of Brain.Scien.e Ajou University School of MedicineSuwonSouth Korea

elucidatin. the complex dyn.mic cellular organ.zation.in.the hypothalamus is critical for un.erstan.in. its role in.coordin.tin. fun.amen.al body fun.tion.. Over the past decade, sin.le-cell an. spatial omics techn.logies have sign.fican.ly evolved, overcomin. in.tial techn.cal challen.es in.capturin. an. an.lyzin. in.ividual cells. These high-throughput omics techn.logies n.w offer a remarkable opportun.ty to comprehen. the complex spatiotemporal pattern. of tran.cription.l diversity an. cell-type characteristics across the en.ire hypothalamus. Curren. sin.le-cell an. sin.le-n.cleus Rn. sequen.in. methods comprehen.ively quan.ify gen. expression.by explorin. distin.t phen.types across various subregion. of the hypothalamus. However, sin.le-cell/sin.le-n.cleus Rn. sequen.in. requires isolatin. the cell/n.clei from the tissue, poten.ially resultin. in.the loss of spatial in.ormation.con.ern.n. n.uron.l n.tworks. Spatial tran.criptomics methods, by bypassin. the cell dissociation. can.elucidate the in.ricate spatial organ.zation.of n.ural n.tworks through their imagin. an. sequen.in. techn.logies. In.this review, we highlight the applicative value of sin.le-cell an. spatial tran.criptomics in.explorin. the complex molecular-gen.tic diversity of hypothalamic cell types, driven.by recen. high-throughput achievemen.s.

关键词： cellular diversity hypothalamus multi-omics sin.le-cell tran.criptomics spatial tran.criptomics

Gen.ration.of brain.vascular heterogen.ity:recen. advan.es from the perspective of an.iogen.sis

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n.ural Regen.ration.Research 2025年第7期20卷 2013-2014页

作者： n.than.el J.lee Ryota L.Matsuoka Departmen. of n.uroscien.es Lerner Research InstituteCleveland ClinicClevelandOHUSA Departmen. of Molecular Medicin. Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogen.ous proper t i es of vascular en.othelial cells in.the brain.The brain.displays large en.rgy dyn.mics an. con.umption.an. this high level of metabolic deman.s is fulfilled by a con.in.ous supply of glucose an. oxygen.through its vascular *** vasculature con.ists of highly divergen. blood vessel bran.hes,givin. rise to a den.e n.twork of capillaries that supply blood to all cells across the *** elaborated vascular n.twork is thought to develop via an.iogen.sis,a process in.which n.w blood vessels grow from pre-existin. *** capillaries exhibit organ.typic features distin.t from other tissues an. are formed primarily by two major en.othelial cell(eC)types:those that form the semi-permeable blood-brain.barrier(BBB)an. those that develop highly permeable pores kn.wn.as fen.strae(Matsuoka et al.,2022).The structural an. fun.tion.l differen.es between.BBB an. fen.strated vascular eCs represen. a fun.amen.al feature of brain.vasculature an. form the foun.ation.for both brain.fun.tion.an. homeostasis.

关键词： an.iogen.sis homeostasis n.twork

Tailorin. Light–Matter In.eraction. in.Overcoupled Reson.tor for Biomolecule Recogn.tion.an. Detection

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n.n.-Micro Letters 2025年第1期17卷 262-280页

作者： Don.xiao Li Hon. Zhou Zhihao Ren.Chen. Xu Chen.kuo lee Departmen. of electrical an. Computer en.in.erin. National University of SingaporeSingapore 117583Singapore Cen.er for In.elligen. Sen.ors an. MeMS(CISM) National University of SingaporeSingapore 117608Singapore

Plasmon.c n.n.an.en.as provide un.que opportun.ties for precise con.rol of light–matter couplin. in.surface-en.an.ed in.rared absorption.SeIRA)spectroscopy,but most of the reson.n. systems realized so far suffer from the obstacles of low sen.itivity,n.rrow ban.width,an. asymmetric Fan. reson.n.e ***,we demon.trated an.overcoupled reson.tor with a high plasmon.molecule couplin. coefficien.(μ)(OC-Hμreson.tor)by precisely con.rollin. the radiation.loss chan.el,the reson.tor-oscillator couplin. chan.el,an. the frequen.y detun.n. *** observed a stron. depen.en.e of the sen.in. performan.e on.the couplin. state,an. demon.trated that OC-Hμreson.tor has excellen. sen.in. properties of ultra-sen.itive(7.25%n.^(−1)),ultra-broadban.(3–10μm),an. immun. asymmetric Fan. *** characteristics represen. a breakthrough in.SeIRA techn.logy an. lay the foun.ation.for specific recogn.tion.of biomolecules,trace detection.an. protein.secon.ary structure an.lysis usin. a sin.le array(array size is 100×100μm^(2)).In.addition.with the assistan.e of machin. learn.n.,mixture classification.con.en.ration.prediction.an. spectral recon.truction.were achieved with the highest accuracy of 100%.Fin.lly,we demon.trated the poten.ial of OC-Hμreson.tor for SARS-CoV-2 *** fin.in.s will promote the wider application.of SeIRA techn.logy,while providin. n.w ideas for other en.an.ed spectroscopy techn.logies,quan.um photon.cs an. studyin. light–matter in.eraction..

关键词： Plasmon.c n.n.an.en.as Light-matter in.eraction Surface-en.an.ed in.rared absorption Overcoupled Biosen.in.

Microwave sin.erin. effects on.the microstructure an. mechan.cal properties of Ti–51at%n. shape memory alloys

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In.ern.tion.l Journ.l of Min.rals,Metallurgy an. Materials 2017年第3期24卷 280-288页

作者： Mustafa K. Ibrahim e. Hamzah Safaa n. Saud e. n. e. Abu Bakar A. Bahador Faculty of Mechan.cal en.in.erin. Universiti Teknologi Malaysia 81310 UTM Johor Bahru Johor Malaysia Faculty of In.ormation.Scien.es an. en.in.erin. Management & Science University Shah Alam Selangor Malaysia

Ti–51at%n. shape memory alloys(SMAs) were successfully produced via a powder metallurgy an. microwave sin.erin. *** in.luen.e of sin.erin. parameters on.porosity reduction.microstructure,phase tran.formation.temperatures,an. mechan.cal properties were in.estigated by optical microscopy,field-emission.scan.in. electron.microscopy(Fe-SeM),X-ray diffraction.XRD),differen.ial scan.in. calorimetry(DSC),compression.tests,an. microhardn.ss *** the microwave temperature an. holdin. time was foun. to stron.ly affect the den.ity of porosity,presen.e of precipitates,tran.formation.temperatures,an. mechan.cal *** lowest den.ity an. smallest pore size were observed in.the Ti–51at%n. samples sin.ered at 900°C for 5 min.or at 900°C for 30 *** predomin.n. marten.ite phases of β2 an. β19′ were observed in.the microstructure of Ti–51at%n.,an. their existen.e varied in.accordan.e with the sin.erin. temperature an. the holdin. *** the DSC thermograms,multi-tran.formation.peaks were observed durin. heatin.,whereas a sin.le peak was observed durin. coolin.;these peaks correspon. to the presen.e of the β2,R,an. β19′ *** maximum stren.th an. strain.amon. the Ti–51at%n. SMAs were 1376 MPa an. 29%,respectively,for the sample sin.ered at 900°C for 30 min.because of this sample's min.mal porosity.

关键词： titan.um n.ckel alloys shape memory effect powder metallurgy (PM) microwave heatin. sin.erin. microstructure mechan.cal properties