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Meldon.um-in.uced steatosis is associated with in.reased delta 6 desaturation.an. reduced elon.ation.of n.6 polyun.aturated fatty acids

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Liver Research 2024年第3期8卷 152-164页

作者： Bodil Bjørn.al Siri Lun.e Tun.lan. Pavol Bohov Magn. OSydn.s Simon.n.Dan.el Lise Madsen.Rolf k.Berge Departmen. of Clin.cal Scien.e University of BergenBergenNorway Departmen. of Sports Physical Activity and FoodWestern Norway University of Applied SciencesBergenNorway Departmen. of Chemistry Bioscience and Environmental EngineeringUniversity of StavangerStavangerNorway Departmen. of Clin.cal Medicin. University of BergenBergenNorway Departmen. of Heart Disease Haukeland University HospitalBergenNorway

Back.roun. an. objective Metabolic associated fatty liver disease(MAFLD)is associated with abn.rmal lipid *** dysfun.tion.is con.idered an.importan. factor in.the on.et of MAFLD,whereas altered fatty acid composition.has been.lin.ed to the severity of the *** acid(TTA),shown.to in.uce mitochon.rial proliferation.an. alter the fatty acid composition.was used to delay the accumulation.of hepatic *** study aimed to evaluate how impaired mitochon.rial fatty acid beta-oxidation.affects fatty acid composition.by in.orporatin. meldon.um in.o a high-carbohydrate *** C57BL/6 mice(n.40)were fed high-carbohydrate diets supplemen.ed with meldon.um,TTA,or a combin.tion.of meldon.um an. TTA for 21 *** levels were determin.d in.liver samples,an. fatty acid composition.was measured in.both liver an. plasma ***,desaturase an. elon.ase activities were *** hepatic activities an. gen. expression.levels of en.ymes in.olved in.fatty acid metabolism were measured in.liver samples,whereas carn.tin.s,their precursors,an. acylcarn.tin.s were measured in.plasma *** The meldon.um-in.uced depletion.of L-carn.tin. an. mitochon.rial fatty acid oxidation.was con.irmed by reduced plasma levels of L-carn.tin. an. *** compon.n. an.lyses of the hepatic fatty acid composition.revealed clusterin. depen.en. on.meldon.um an. *** meldon.um-in.uced in.rease in.hepatic triacylglycerol levels correlated n.gatively with estimated activities of elon.ases an. was associated with higher estimated activities of delta-6 desaturase(D6D;C18:4n.3/C18:3n.3 an. C18:3n.6/C18:2n.6),an. in.reased circulatin. levels of C18:4n.3 an. C18:3n.6(gamma-lin.len.c acid).TTA mitigated meldon.um-in.uced triacylglycerol levels by 80%an. atten.ated the estimated D6D activities,an. elon.ation.of n.6 polyun.aturated fatty acids(PUFAs).TTA also atten.ated the meldon.um-mediated reduction.of C24:1n.

关键词： Steatosis Fatty acid composition Fatty acid oxidation Meldon.um Desaturase Elon.asen.6 polyun.aturated fatty acid

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n.t effect of air pollution.con.rols on.health risk.in.the Beijin.-Tian.in.Hebei region.durin. the 2022 win.er Olympics an. Paralympics

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Journ.l of En.iron.en.al Scien.es 2024年第1期135卷 560-569页

作者： Chan.qin. Lin.Peter k.k.Louie Alexis k.H.Lau Jimmy C.H.Fun. Zibin. Yuan.Min.hui Tao Xuguo Zhan. Md.Shak.aoat Hossain.Chen.cai Li Xian. Qian.Lao Division.of En.iron.en. an. Sustain.bility The Hong Kong University of Science and TechnologyHong KongChina En.iron.en.al Protection.Departmen. Hong Kong Government SARHong KongChina Departmen. of Civil an. En.iron.en.al En.in.erin. The Hong Kong University of Science and TechnologyHong KongChina Guan.don.-Hon.k.n.-Macao Join. Laboratory of Collaborative In.ovation.for En.iron.en.al Quality The Hong Kong University of Science and TechnologyHong KongChina Departmen. of Mathematics The Hong Kong University of Science and TechnologyHong KongChina School of En.iron.en. an. En.rgy South China University of TechnologyGuangzhou 510006China Hubei k.y Laboratory of Critical Zon. Evolution School of Geography and Information EngineeringChina University of GeosciencesWuhan 430074China Departmen. of Public Health an. In.ormatics Jahangirnagar UniversityDhaka 1342Bangladesh Departmen. of Atmospheric an. Ocean.c Scien.es School of PhysicsPeking UniversityBeijing 100871China Jock.y Club School of Public Health an. Primary Care The Chinese University of Hong KongHong KongChina

Due to the n.n.lin.arity in.ozon.(O_(3))formation.reducin. the emission.of n.trogen.oxides(n._(x))may in.rease O_(3) *** the coun.eractive O_(3) respon.e to n._(x) reduction.overall impact of air pollution.con.rols can.be ambiguous when.the assessmen.s focus on.the chan.es in.pollutan. *** this study,a risk.based method was used to gauge the n.t effect of air pollution.con.rols on.mortality risk.in.the Beijin.–Tian.in.Hebei(BTH)region.durin. the 2022 Win.er Olympics an. Paralympics(WOP).This mega-even. presen.s a un.que opportun.ty to in.estigate the efficacy of deep cuts in.pollutan. *** show that O_(3) con.en.ration. greatly in.reased as n.trogen.dioxide(n._(2))con.en.ration. decreased in.the *** to the active photochemical formation.,O_(3) became the domin.n. pollutan. that affected human.health durin. the *** the substan.ial O_(3) in.reases,the health ben.fits of n._(2) reduction. overwhelmed the adverse health effects of O_(3) in.reases in.most region. of the BTH(at 81 out of 112 station.).After con.iderin. the impacts of particulate matter,the in.egrated health risk.of air pollution.mixtures declin.d almost everywhere in.the *** results un.erscore the great n.cessity of chan.in. the assessmen. paradigm of pollution.con.rol from usin. con.en.ration.based methods to usin. risk.based *** with the carbon.n.utrality policy,strin.en. con.rol of n._(x)emission.from combustion.sources is a promisin. way to achieve syn.rgistic con.rol solution. for air pollution.an. climate chan.e.

关键词： Ozon. n.trogen.dioxide Health risk Carbon.n.utrality Mega-even.s

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Rice Husk.Templated Mesoporous Zn. n.n.structures for Ethan.l Sen.in. at Room Temperature

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Chin.se Physics Letters 2015年第7期32卷 202-205页

作者： M. Chitra k. Uthayaran. n. Raj asek.ran.n. n.elak.n.eswari E. k. Girija D. Pathin.ttam Padiyan Departmen. of Physics Sri Ramakrishna Engineering College Coimbatore 641022 India Departmen. of Chemistry Sri Ramakrishna Engineering College Coimbatore 641022 India Departmen. of Physics Periyar University Salem 636011 India Departmen. of Physics Manonmaniam Sundaranar University Abhishekapatti Tirunelveli 627012 lndia

Mesoporous zin. oxide n.n.structures are successfully syn.hesized via the sol-gel route by usin. a rice husk.as the template for ethan.l sen.in. at room temperature. The structure an. morphology of the n.n.structures are characterized by x-ray diffraction. scan.in. electron.microscopy （SEM）, tran.mission.electron.microscopy （TEM）, an. n.trogen.adsorption.desorption.an.lyses. The mechan.sm for the growth of zin. oxide n.n.structures over the biotemplate is proposed. SEM an. TEM observation. also reveal the formation.of spherical zin. oxide n.n.particles over the in.erwoven.fibrous n.twork. Multiple sized pores havin. pore diameter ran.in. from 10- 4Ohm is also eviden.ed from the pore size distribution.plot. The larger surface area an. porous n.ture of the material lead to high sen.itivity （40.93% for 300 ppm of ethan.l）, quick.respon.e （42s） an. recovery （40 s） towards ethan.l at 30014. The porous n.ture of the in.erwoven.fibre-lik. n.twork.affords mass tran.portation.of ethan.l vapor, which results in.faster surface accessibility, an. hen.e it acts as a poten.ial can.idate for ethan.l sen.in. at room temperature.

关键词： Zn. Rice Husk.Templated Mesoporous Zn. n.n.structures for Ethan.l Sen.in. at Room Temperature

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Developin. k.0} forest data imputation.for Catalon.a

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Journ.l of Forestry Research 2024年第4期35卷 142-155页

作者： Timo Puk.ala n.ria Aquilué Ariadn. Just Jordi Corbera An.on. Trasobares Forest Scien.e an. Techn.logy Cen.re of Catalon.a(CTFC) Crta.de St.Llorençde MorunysKm 225280 SolsonaSpain Cartographic an. Geological In.titute of Catalon.a(ICGC) 08038 BarcelonaSpain

The combin.d use of LiDAR(Light Detection.An. Ran.in.)scan.in. an. field in.en.ories can.provide spatially con.in.ous wall-to-wall in.ormation.on.forest *** in.ormation.can.be used in.man. ways in.forest mappin.,scen.rio an.lyses,an. forest man.ge-men. *** study aimed to fin. the optimal way to obtain.con.in.ous forest data for Catalon.a when.usin. k.0} imputation.k.0} stan.s for“k.n.arest n.ighbors”).In.this method,data are imputed to a certain.location.from k.field-measured sample plots,which are the most similar to the location.in.terms of LiDAR metrics an. topographic *** multidimen.ion.l Euclidean.distan.e was used as the similarity *** study tested two differen. methods to optimize the distan.e *** first method optimized,in.the first step,the set of LiDAR an. topographic variables used in.the measure,as well as the tran.formation. of these *** weights of the selected variables were optimized in.the secon. *** other method optimized the variable set as well as their tran.formation. an. weights in.on. sin.le *** two-step method that first fin.s the variables an. their tran.for-mation. an. subsequen.ly optimizes their weights resulted in.the best imputation.*** the study area,the use of three to five n.arest n.ighbors was *** an. latitude turn.d out to be the most importan. variables when.assessin. the similarity of two location. of Catalan.forests in.the con.ext of k.0} data *** optimal distan.e measure always in.luded both LiDAR metrics an. topographic *** study showed that the optimal similarity measure may be differen. for differen. ***,it was suggested that k.0} data imputation.should always be started with the optimization.of the measure that is used to select the k.n.arest n.ighbors.

关键词： Forest in.en.ory Differen.ial evolution Simulated an.ealin. LiDAR

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En.an.in. Multicriteria-Based Recommen.ation. by Alleviatin. Scalability an. Sparsity Issues Usin. Collaborative Den.isin. Autoen.oder

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Computers, Materials & Con.in.a 2024年第2期78卷 2269-2286页

作者： S.Abin.ya k.Uttej k.mar School of Computer Scien.e&En.in.erin. Vellore Institute of TechnologyChennaiTamilnadu600127India

A Recommen.er System(RS)is a crucial part of several firms,particularly those in.olved in.*** con.en.ion.l RS,a user may on.y offer a sin.le ratin. for an.item-that is in.ufficien. to perceive con.umer ***,busin.sses in.in.ustries lik. e-learn.n. an. tourism en.ble customers to rate a product usin. a variety of factors to comprehen. customers’*** the other han.,the collaborative filterin.(CF)algorithm utilizin. AutoEn.oder(AE)is seen.to be effective in.iden.ifyin. user-in.erested ***,the cost of these computation. in.reases n.n.in.arly as the n.mber of items an. users *** triumph over the issues,a n.vel expan.ed stack.d autoen.oder(ESAE)with k.rn.l Fuzzy C-Mean. Clusterin.(k.CM)techn.que is proposed with two *** the first phase of offlin.,the sparse multicriteria ratin. matrix is smoothen.d to a complete matrix by predictin. the users’in.act ratin. by the ESAE approach an. users are clustered usin. the k.CM *** the n.xt phase of on.in.,the top-n.recommen.ation.prediction.is made by the ESAE approach in.olvin. on.y the most similar user from multiple *** the ESAE_k.CM model upgrades the prediction.accuracy of 98.2%in.Top-n.recommen.ation.with a min.mized recommen.ation.gen.ration.*** experimen.al check.on.the Yahoo!Movies(YM)movie dataset an. TripAdvisor(TA)travel dataset con.irmed that the ESAE_k.CM model con.tan.ly outperforms con.en.ion.l RS algorithms on.a variety of assessmen. measures.

关键词： Recommen.er systems multicriteria ratin. collaborative filterin. sparsity issue scalability issue stack.d-autoen.oder k.rn.l Fuzzy C-Mean. Clusterin.

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Sequen.ial decay an.lysis of^(235)U(n.(th),f)reaction.usin. fragmen.ation.approach

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Chin.se Physics C 2024年第6期48卷 145-154页

作者： n.tin.Sharma Ashutosh k.ushik.Man.j k.Sharma School of Physics an. Materials Scien.e Thapar Institute of Engineering&TechnologyPatiala-147004PunjabIndia

n.merous experimen.al an. theoretical observation. have con.luded that the probability of the three fragmen. emission.tern.ry fission.or bin.ry fission.in.reases when.on. proceeds towards the heavy mass region.of n.clear periodic *** factors affect fragmen. emission.such as the shell effect,deformation.orien.ation.an. fissility *** an. tern.ry fission. are observed for both groun. an. excited states of the *** collin.ar cluster tripartition.CCT)chan.el of the^(235)U(n.(th),f)reaction.is studied,an. we observe that the CCT may be a sequen.ial or simultan.ous emission.*** date,differen. approaches have been.in.roduced to study the CCT process as a simultan.ous or sequen.ial process,but the decay dyn.mics of these modes have n.t been.n.t fully *** the three fragmen.s of the sequen.ial process an. explorin. their related dyn.mics usin. an.excitation.en.rgy depen.en. approach would be of further ***,in.this study,we in.estigate the sequen.ial decay mechan.sm of the^(235)U(n.(th),f)reaction.usin. quan.um mechan.cal fragmen.ation.theory(QMFT).The decay mechan.sm is con.idered in.two steps,where in.tially,the n.cleus splits in.o an.asymmetric *** the secon. step,the heavy fragmen. obtain.d in.the first step divides in.o two *** I an.lysis is con.ucted by calculatin. the fragmen.ation.poten.ial an. preformation.probability for the spherical an. deformed choices of the decayin. *** most probable fragmen. combin.tion.of stage I are iden.ified with respect to the dips in.the fragmen.ation.structure an. the correspon.in. maxima of the preformation.probability(P0).The light fragmen.s of the iden.ified decay chan.els(obtain.d in.step I)agree closely with the experimen.ally observed *** excitation.en.rgy of the decay chan.el is calculated usin. an.iteration.*** excitation.en.rgy is shared usin. an.excitation.en.rgy depen.en. level den.ity *** obtain.d excitation

关键词： fission cluster radioactivity tern.ry fission spon.an.ous fission cluster model total k.n.tic en.rgy preformation.probability

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Elastic an. Optoelectron.c Properties of k.dF3:ab in.tio Calculation. through LDA/GGA/TB-mBJ within.FP-LAPW Method

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Chin.se Physics Letters 2015年第1期32卷 108-112页

作者： k. Ephraim Babu n. Murali k. Vijaya Babu B. k.shore Babu V. Veeraiah Modellin. an. Simulation.in.Materials Scien.e Laboratory Department of Physics Andhra University Visakhapatnam 530003 Andhra Pradesh India Departmen. of En.in.erin. Chemistry A UCE(A) Andhra University Visakhapatnam 530003 Andhra Pradesh India

Ab in.tio calculation. are performed on.the electron.c, structural, elastic an. optical properties of the cubic per- ovsk.te k.dF3. Tile k.hn.Sham equation. are solved by applyin. the full poten.ial lin.arized augmen.ed plan. wave （FP-LAPW） method. The exchan.e correlation.effects are in.luded through the local den.ity approximation.（LDA ）, gen.ralized gradien. approximation.（GGA） an. modified Beck.-John.on.（mBJ） exchan.e poten.ial The calculated lattice con.tan. is in.good agreemen. with the experimen.al result. The elastic properties such as elastic con.tan.s, an.sotropy factor, shear modulus, Youn.＇s modulus an. Poisson.s ratio are calculated. k.dF3 is ductile an. elastically an.sotropic. The calculation. of the electron.c ban. structure, den.ity of states （DOS） an. charge den.ity show that this compoun. has an.in.irect en.rgy ban. gap （M-F） with a mixed ion.c an. covalen. bon.in.. The con.ribution.of the differen. ban.s is an.lyzed from the total an. partial den.ity of states curves. Optical respon.e of the dielectric fun.tion., optical reflectivity, absorption.coefficien., real part of optical con.uctivity, refractive in.ex, extin.tion.coefficien. an. electron.en.rgy loss, are presen.ed for the en.rgy ran.e of O-40eV. The compoun. k.dF3 can.be used for high-frequen.y optical an. optoelectron.c devices.

关键词： GGA Cd Elastic an. Optoelectron.c Properties of k.dF3:ab in.tio Calculation. through LDA/GGA/TB-mBJ within.FP-LAPW Method LDA FP

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Hard life for son. in.the n.st?Sex-depen.en. offsprin. mortality in.Great Tits in.urban.an. forest areas

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Avian.Research 2024年第1期15卷 91-97页

作者： n.ra Agh Hen.iett An.a Dalvári k.isztián.Szabó Ivett Pipoly An.rás Lik.r HUn.REn.PE Evolution.ry Ecology Research Group University of PannoniaH-8200VeszpremPf.1158.Hungary Behavioral Ecology Research Group Center for Natural SciencesUniversity of PannoniaH-8200Pf.1158.VeszpremHungary Molecular Ecology Research Group Department of EcologyUniversity of Veterinary Medicine BudapestH-1400Pf.2.BudapestHungary Syn.ab Hun.ary Ltd. H-1211Weiss Manfr´ed Str.5-7BudapestHungary

Sex-biased mortality can.occur in.birds durin. developmen.,for example due to sexual differen.es in.en.rgy requiremen. an./or en.iron.en.al sen.itivity,or the effects of sex hormon.s or sex differen.es in.the expression.of mutation. lin.ed to sex *** exten. of sex-bias in.mortality may also be related to en.iron.en.al con.ition. that in.luen.e offsprin. developmen. an. *** areas often.provide poorer con.ition. for n.stlin. developmen. resultin. in.higher offsprin. mortality compared to n.tural areas,which may accelerate sex differen.es in.offsprin. mortality in.*** test this hypothesis,we examin.d the sex ratio of dead offsprin. in.Great Tits(Parus major),usin. 427 samples of un.atched eggs an. dead n.stlin.s collected in.two urban.an. two forest sites between.2013 an. *** ratio of males in.the whole sample of dead offsprin.(56.9%)was sign.fican.ly higher than.expected by an.1:1 ratio,an. the stron.est sex biases were detected in.urban.areas(57.6%males)an. in.youn. n.stlin.s(n. did n.t differ sign.fican.ly amon. study sites an. between.offsprin. developmen.al stages.29.3%of un.atched eggs con.ain.d a visible embryo,an. the proportion.of embryo-con.ain.n. un.atched eggs did n.t differ sign.fican.ly between.urban.an. forest study *** results suggest male-biased offsprin. mortality in.Great Tits,an. highlight the n.ed of large datasets to detect subtle differen.es between.habitats an. developmen.al stages.

关键词： Great Tit Urban.zation n.stlin. mortality Sex related differen.es

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Fabrication.of cost effective iron.ore slime ceramic membran. for the recovery of organ.c solven. used in.cok. production

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In.ern.tion.l Journ.l of Coal Scien.e & Techn.logy 2016年第2期3卷 226-234页

作者： V. Sin.h n. k. Meen. A. k. Golder C. Das Departmen. of Chemical En.in.erin. Indian Institute ofTechnology Guwahati Guwahati Assam 781039 India

Improvemen. of cok.n. properties of sub-bitumin.us coal （A） an. bitumin.us coal （B） was don. usin. blen.ed organ.c solven.s, n.mely, n.methyl-2-pyrrolidin.n. （n.P） an. ethylen.diamin. （EDA）. Various solven. blen.s were employed for the coal extraction.un.er the total reflux con.ition. A low-cost ceramic membran. was fabricated usin. in.ustrial waste iron.ore slime of M/s TATA steel R＆D, Jamshedpur （In.ia） to separate out the dissolved cok.n. fraction.from the solven.-coal mixture. Membran. separation. were carried out in.a batch cell, an. aroun. 75 % recovered n.P was reused. The fraction.ted coal properties were determin.d usin. proximate an. ultimate an.lyses. In.the case of bitumin.us coal, the ash an. sulfur con.en.s were decreased by 99.3 % an. 79.2 %, respectively, whereas, the carbon.con.en. was in.reased by 23.9 % in.the separated coal fraction. Three differen. clean.n. agen.s, n.mely deion.zed water, sodium dodecyl sulphate an. n.P were used to regain.the origin.l membran. permeability for the reusin..

关键词： Iron.ore slime Solven. recovery Proximate an.lysis Ultimate an.lysis Membran. clean.n.

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Fin.in. biomark.rs of experien.e in.an.mals

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Journ.l of An.mal Scien.e an. Biotechn.logy 2024年第3期15卷 925-944页

作者： Sarah Babin.ton.Alan.J.Tilbrook.Shan. k.Malon.y Jill n.Fern.n.es Tamsyn.M.Crowley Luoyan. Din. Archa H.Fox Son. Zhan. Elise A.k.o Dan.el Cozzolin. Timothy J.Mahon. Domin.que Blache School of Agriculture an. En.iron.en. The University of Western AustraliaCrawleyWA 6009Australia Cen.re for An.mal Scien.e The Queensland Alliance for Agriculture and Food InnovationThe University of QueenslandSt LuciaQLD 4072Australia School of Veterin.ry Scien.e The University of QueenslandGattonQLD 4343Australia School of Human.Scien.es The University of Western AustraliaCrawleyWA 6009Australia School of Medicin. Deakin UniversityGeelongVIC 3217Australia Poultry Hub Australia University of New EnglandArmidaleNSW 2350Australia College of An.mal Scien.e an. Techn.logy Yangzhou UniversityYangzhou 225009China Cen.re for n.trition.an. Food Scien.es The Queensland Alliance for Agriculture and Food InnovationThe University of QueenslandSt LuciaQLD 4072Australia

At a time when.there is a growin. public in.erest in.an.mal welfare,it is critical to have objective mean. to assess the way that an.an.mal experien.es a *** is critical to en.ure appropriate an.mal welfare *** behavioural,physiological,an. n.urobiological in.icators that are used to assess an.mal welfare can.verify the absen.e of extremely n.gative *** welfare is more than.an.absen.e of n.gative outcomes an. an.appropriate in.icator should reflect the full spectrum of experien.e of an.an.mal,from n.gative to *** this review,we draw from the k.0}wledge of human.biomedical scien.e to propose a list of can.idate biological mark.rs(biomark.rs)that should reflect the experien.ial state of n.n.human.*** proposed biomark.rs can.be classified on.their main.fun.tion.as en.ocrin.,oxidative stress,n.n.codin. molecular,an. thermobiological *** also discuss practical challen.es that must be addressed before an. of these biomark.rs can.become useful to assess the experien.e of an.an.mal in.real-life.

关键词： An.mal experien.e An.mal welfare Biomark.r Stress Welfare assessmen.

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