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Seroprevalen.e an. Molecular Biodiverisity of.Hepatitis C In.ection.in.Con.olese Diabetics

Open.journ.l of.Gastroen.erology 2019年第1期9卷 22-27页

作者： A. Mon.o-On.ouo M. G. Ibobi Gassaye Deby E. Bouen.zabila C. P. Ahoui Apen.i n. a.dzoua.a.mba.ognoua.j. f. mimiesse mona.ou A. Boumba n. A. Itoua-n.aporo B. I. Atipoibara H. G. monabeka j.-R. Ibara Departmen. of.Gastroen.erology an. In.ern.l Medicin. Brazzaville University Hospital Center Brazzaville Congo f.culty of.Health Scien.es Ngouabi Marien University Brazzaville Congo Departmen. of.Metabolic Diseases of.Brazzaville Un.versity Hospital Cen.er Brazzaville Congo Laboratory Service Hospital Gen.ral of.Louan.jili Pointe- Noire Congo

Summary: There is n. eviden.e f.r comorbidity diabetes an. hepatitis C virus in.ection.in.the Con.o. The aim of.this work was to determin. the seroprevalen.e an. molecular biodiversity of.HCV in.order to con.ribute to improvin. the man.gemen. of.Con.olese diabetics. Patien.s an. methods: It was a cross-section.l study that took place f.om 1 f.bruary to 30 September 2018 at the Brazzaville Un.versity Hospital, the Diabcare Health Cen.er an. the Adolphe Cissé Hospital in.Poin.e-n.ire. It con.ern.d diabetic patien.s f.llowed in.Brazzaville an. Poin.e-n.ire agreein. to the study, af.er obtain.n. the opin.on.of.the ethics committee of.the research in.health scien.e. All samples collected were screen.d f.r the presen.e of.an.i HCV Ab usin. a rapid ALERE HCV test an. the Mon.lisa HCV Ag-Ab ultra test f.r con.irmation.in.Con.o. Detection.of.the viral Rn. was don. by PCR retrotran.cription.an. gen.typin. was perf.rmed accordin. to the reverse hybridization.techn.que in.f.an.e. Data an.lysis was don. with EpiIn.o 6.0 sof.ware (2016);the proportion. were compared usin. the Chi-square test or the f.sher test at the sign.f.can.e level of.5%. Results: Of.447 patien.s with diabetes mellitus, 49 had HCV positive serology an. the sex ratio was 0.63. Seroprevalen.e of.AC an.i HCV was 11% (49/447);HCV Rn. was detectable in.71.4% (n.= 35) patien.s. The average age of.the population.was 62 ± 10 years with extremes ran.in. f.om 26 to 82 years. The circulatin. gen.types were 4 (97.1%) an. 1 (2.8%). Subtypin. was def.n.d in.17.64% (n.= 6) of.gen.type 4 patien.s;un.ef.n.d in.82.36% (n.= 28) of.Gen.type 4 patien.s, an. in.on. of.gen.type 1 patien.s. The subtypes iden.if.ed were subtype 4e (60%), subtype 4e (8.8%), subtype 4a/4c/4d (5.8%), an. subtype 4h (2.9%). Con.lusion. The prevalen.e of.HCV is high in.our study. These are importan. data f.r the improvemen. of.the man.gemen. of.diabetics.

关键词： Hepatitis C Diabete Con.o

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Assessmen. of.Practice of.Colon.scopy in.Pediatrics in.Brazzaville, Con.o

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Open.journ.l of.Pediatrics 2022年第3期12卷 577-581页

作者： A. Mon.o-On.ouo L. C. Atipo-Ibara Ollan.zobo Ikobo C. P. Ahoui Apen.i j. f. mimiesse mona.ou n. A. Itoua-n.Gaporo Deby Gassaye M. n.alessami Mouakosso C. S. Adoua B. I. Atipo Ibara j. R. Ibara Gastro-En.erology an. In.ern.l Medicin. CHU of Brazzaville Brazzaville Congo f.culty of.Health Scien.es Ngouabi Marien University Brazzaville Congo In.an. Pediatric Service CHU of Brazzaville Brazzaville Congo

Backgroun.: In.Con.o, there is n. pediatric gastroen.erology departmen. an. the activity of.colon.scopy has n.ver been.evaluated. The aim of.this study is to report the in.ication. an. the results of.pediatric colon.scopy in.Brazzaville. Methods: A retrospective study was con.ucted f.om jan.ary 2016 to August 2017 by an.lyzin. reports of.colon.scopy perf.rmed in.the gastroen.erology departmen. in.Brazzaville. Sex, prescribers, in.ication. an. results of.colon.scopy were the variables study. Results: over the 19-mon.h period, 489 colon.scopies have been.perf.rmed, in.which 13 (2.7%) colon.scopies were perf.rmed in.children.un.er 17 years, with an.average age of.9.8 ± 4.6 (8 males an. 6 f.males) an. the extreme ran.in. f.om 1 - 17 years. The sex ratio (H/f. was 1.6. The prescribers were gastroen.erologist (n.= 4), pediatrician.(n.= 4), surgeon. (n.= 2), gen.ral practition.rs (n.= 2), pediatric studen.s (n.= 1). Chron.c bowel in.lammatory diseases an. polypectomy was the most f.equen. con.ition. f.r colon.scopy in.ication. Seven.(7) colon.scopies were n.rmal. 4 cases were recto-polyps, an. 2 cases were ulcerative colitis. Con.lusion. pediatric colon.scopy is a powerf.l diagn.stic an. therapeutic mean.. The pediatrician. should thin. about it to improve the man.gemen. of.children.with digestive symptoms that meet the in.ication. of.pediatric colon.scopy.

关键词： Pediatric Colon.scopy Practice Brazzaville

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Seroprevalen.e an. Molecular Biodiversity of.Hepatitis B an. Delta Virus In.ection. in.the Republic of.Con.o

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Open.journ.l of.Gastroen.erology 2018年第12期8卷 448-454页

作者： A. Mon.o-On.ouo R. Itoko Okombi A. Boumba f. R. n.ama C. P. Ahoui-Apen.i j. f. mimiesse mona.ou n. A. Itoua-n.aporo L. C. Atipo-Ibara Ollan.zobo Ikobo Deby Gassaye M. n.alessami Mouakosso C. S. Adoua B. I. Atipo-Ibara j.-R. Ibara Gastro-En.erology an. In.ern.l Medicin. CHU of Brazzaville Brazzaville Congo f.culty of.Health Scien.es Ngouabi Marien University Brazzaville Congo Laboratory Service Hospital Gen.ral of.Louan.jili Pointe-Noire Congo n.tion.l Public Health Laboratory Brazzaville Congo In.an. Pediatric Service CHU of Brazzaville Brazzaville Congo

Hepatitis B virus (HBV) in.ection.is a major public health problem in.the world. In.Con.o, studies on.the prevalen.e of.HBV in.ection.are common.but HDV in.ection.is rare. Objective: Con.ribute to improve the man.gemen. an. preven.ion.of.HBV an. HDV in.ection.. Patien.s an. Methods: This was a descriptive an. cross-section.l study con.ucted f.om jan.ary to August 2016 in.the health services of.the various departmen.s of.Con.o an. at the n.tion.l public health laboratory in.Brazzaville. All patien.s with HBsAg surf.ce an.igen.who were at least 18 years old an. who con.en.ed to the study were in.luded. The HBs an.igen.was f.rst tested by a rapid test then.con.irmed by ELISA. All HBsAg positive patien.s were subsequen.ly subjected to a secon. ELISA test f.r Delta an.ibody. The techn.ques of.extraction.an. con.en.ion.l an. specif.c gen. amplif.cation.were carried out on.plasma f.r the iden.if.cation.of.the gen.types of.the two viruses. The data an.lysis was don. with EpiIn.o V7 sof.ware. The proportion. were compared usin. the Chi-square test or the f.sher test at the sign.f.can.e level of.5%. Results: 1618 subjects were in.luded, of.whom 180 were positive f.r HBsAg, a f.equen.y of.11.12%. The sex ratio (M/f. was 0.77%, the mean.age was 40.2 ± 15.6 years with extremes ran.in. f.om 18 to 88 years. Of.the 180 HBsAg positive, 22 were an.i-VHD positive, a f.equen.y of.12.22%. HBV Dn. was amplif.ed in.83.8% (151/180), HDV Rn. in.63.6% (14/22). f.r HBV, three gen.types were iden.if.ed: E (46.9%), A (43.7%) an. D (9.4%), however f.r VHD three gen.types D1, D5, D8 were iden.if.ed. Con.lusion. Co-in.ection.of.hepatitis B an. Delta viruses is common.in.Con.o. The man.gemen. an. preven.ion.of.hepatitis B must take in.o accoun. the reality of.this co-in.ection.

关键词： Seroprevalen.e Molecular Biodiversity Hepatitis B Virus an. Delta Con.o

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