检索结果-南通市图书馆

Microstructures an. properties of 6016 alumin.m alloy with gradien. composition

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2021年第8期40卷 2154-2159页

作者： Xian.-Jie Wan. wei Sun.Jun.Fu Chen.Fu-Yue Wan. Lei Li Jian.Zhon. Cui Key Laboratory of Electromagn.tic Processin. of Materials Ministry of EducationNortheastern UniversityShenyang110819China

weight reduction.plays an.importan. role in.reducin. fuel an. emission.,an. the heat-treatable 6016 alumin.m alloy exhibits excellen. application.prospect in.automobile *** this paper,in.ot with con.tan. Mg/Si ratio an. decreased Mg an. Si con.en.s was *** the microstructure an. the texture of 6016 alumin.m alloy plate design.d with differen. alloy composition. at the top/bottom were systematically in.estigated by electron.backscatter diffraction.techn.logy(EBSD)measuremen.,as well as the room-temperature mechan.cal properties at the differen. position. with composition.*** results in.icate that as Mg an. Si con.en.s in.rease,the grain.size decreases,improvin. the cube texture with recrystallization.an. weaken.n. the S *** stren.th of 6016 alumin.m alloy decreases with lower Mg an. Si con.en.s.

关键词： 6016 Alumin.m alloy plate Mg an. Si con.en.s Mechan.cal properties

落石对缓冲土层的冲击力及冲击深度理论与试验研究

在线全文

学校读者我要写书评

暂无评论

西南交通大学学报 2024年第5期59卷 1078-1085页

作者：王玉锁杨竣翔肖宗扬李传宝田四明王伟姚庆晨赵状西南交通大学土木工程学院四川成都611752 中国铁路经济规划研究院有限公司北京100080

为阐明基于Hertz接触理论的落石冲击力、冲击深度计算方法及缓冲土层强化系数确定方法的适用性和可行性,通过足尺模型试验、反演分析及数理统计,开展体积约1 m^(3)重约2 t的立方体和球顶锥体2种落石形状、1~10 m下落高度及0.5~2.0 m缓... 详细信息

为阐明基于Hertz接触理论的落石冲击力、冲击深度计算方法及缓冲土层强化系数确定方法的适用性和可行性,通过足尺模型试验、反演分析及数理统计,开展体积约1 m^(3)重约2 t的立方体和球顶锥体2种落石形状、1~10 m下落高度及0.5~2.0 m缓冲土层厚度的落石冲击试验研究,进行砂土缓冲层强化系数的确定及落石冲击力、冲击深度理论与试验结果的对比分析.研究结论表明:根据试验结果反演分析,99.7%置信区间的砂土缓冲层强化系数建议取值范围为0.25~10.00 Gn.m^(5/2);理论计算得到的立方体落石冲击力均值较试验值平均偏大140%,球顶锥体偏大21%;理论计算得到的立方体落石冲击深度均值较试验值平均偏大112%,球顶锥体偏大5%;在强化系数99.7%置信区间内计算得到的落石冲击力和冲击深度范围值可包含全部的落石冲击力和冲击深度;相同条件下球顶锥体落石的冲击深度试验值大于立方体的冲击深度试验值,缓冲层厚度越大时冲击深度增大,而落石冲击力离散性较大,与落石形状和缓冲层厚度无明显相关性.

关键词：落石冲击力落石冲击深度缓冲土层弹塑性强化

同方期刊数据库

Effects of brin.olamide on.rabbit ocular blood flow in.vivo an. ex vivo

在线全文

学校读者我要写书评

暂无评论

In.ern.tion.l Journ.l of Ophthalmology(En.lish edition. 2018年第5期11卷 719-725页

作者： Ya-Ru Don. Shi-wei Huan. Ji-Zhe Cui Takeshi Yoshitomi Departmen. of Ophthalmology the Second Hospital of Jilin University Departmen. of Ophthalmology Akita University School of Medicine

AIM：To in.estigate if sign.fican. improvemen. of optic disc blood flow（ODBF） occurs after in.tillation.of brin.olamide on.o rabbit ***：Testin. of bilateral in.raocular pressure（IOP） an. left ODBF in.10 male rabbits took place every 3 h over a 24 h ***（1% ophthalmic solution.two drops at 9：00 an. 21：00） was admin.stered to the left ***,assessed usin. laser speckle flowgraphy,was determin.d as the mean.blur rate（MBR）.Furthermore,the effect of brin.olamide on.isolated rabbit ciliary arteries usin. isometric ten.ion.recordin. system was ***：After brin.olamide in.tillation.IOP was sign.fican.ly decreased in.the left ***-vessel was greater at 18：00 an. 21：00（P〈0.05） than.in.the *** an. MBR-average were greater at 18：00（P〈0.05） than.in.the *** isolated arteries pre-con.racted with a high-K solution.brin.olamide in.uced con.en.ration.depen.en. relaxation.reachin. 46.1%±9%（n.21） at 1 mmol/*** Ca^2＋-free solution.,in.ubation.with brin.olamide suppressed 1 μmol/L histamin.-in.uced con.raction.（P〈0.05）.COn.LUSIOn.Brin.olamide decreases IOP an. in.reases ocular blood *** direct vasodilatory effect of brizolamide is mediated by suppression.of Ca^2＋ release from in.racellular calcium stores.

关键词： brin.olamide ocular blood flow vasodilation in.raocular pressure ciliary artery

Extraction.of copper ion. by supercritical carbon.dioxide

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journ.l of En.iron.en.al Scien.es 2000年第4期12卷 444-447页

作者： Cui, Z. Liu, J. Gao, L. wei, Y. Dept. of En.iron.en.al En.in.erin. Shandong University Jinan 250100 China

Complexation.combin.d with supercritical fluid extraction.was used to extract Cu2+ in.this study. The effects of pressure, temperature, volume of CO2 on.the efficien.y of extraction.were systematically in.estigated. At the optimum con.ition.a 57.32% recovery was achieved. Addition.of suitable amoun. of methan.l (v/v = 5%) to the supercritical CO2 can.in.rease in.the extraction.of Cu2+ (72.69%, RSD = 2.12%, n.= 3). An. the recovery can.further in.rease in.the presen.e of n.n.ion.c surfactan. Triton.X-100 because of its fun.tion.of solubilization. Surfactan. was first used in.the extraction.of metal ion. in.the presen. study, an. the results are satisfied (90.52%, RSD = 2.20%, n.= 3).

关键词： Carbon.dioxide Chelation Copper Methan.l Positive ion. Pressure effects Solubility Surface active agen.s Thermal effects

Tun.n. the selectivity of n.tural oils an. fatty acids/esters deoxygen.tion.to biofuels an. fatty alcohols:A review

在线全文

学校读者我要写书评

暂无评论

Green.En.rgy & En.iron.en. 2023年第3期8卷 722-743页

作者： Yin.don. Zhou Javier Remon.Zhichen. Jian. Avtar S.Matharu Chan.wei Hu Key Laboratory of Green.Chemistry an. Techn.logy Ministry of EducationCollege of ChemistrySichuan UniversityChengduSichuan 610064China In.tituto de Carboquímica CSICZaragoza50018Spain Departmen. of Biomass Scien.e an. En.in.erin. Sichuan UniversityChengdu610064China n.tion.l En.in.erin. Research Cen.er of Clean.Techn.logy in.Leather In.ustry Sichuan UniversityChengdu610064China Green.Chemistry Cen.re of Excellen.e Department of ChemistryUniversity of YorkHeslingtonYorkYO105DDUK

The chemical tran.formation.of n.tural oils provides altern.tives to limited fossil fuels an. produces compoun.s with added value for the chemical *** selective deoxygen.tion.of n.tural oils to diesel-ran.ed hydrocarbon.,bio-jet fuels,or fatty alcohols with con.rollable selectivity is especially attractive in.n.tural oil feedstock *** review presen.s recen. progress in.catalytic deoxygen.tion.of n.tural oils or related model compoun.s(e.g.,fatty acids)to ren.wable liquid fuels(green.diesel an. bio-jet fuels)an. valuable fatty alcohols(un.saturated an. saturated fatty alcohols).Besides,it discusses an. compares the existin. an. poten.ial strategies to con.rol the product selectivity over heterogen.ous *** research con.ucted an. reviewed has on.y addressed the production.of on. category;therefore,a n.w in.egrative vision.explorin. how to direct the process toward fuel an./or chemicals is urgen.ly ***,work con.ucted to date addressin. the developmen. of n.w catalysts an. studyin. the in.luen.e of the reaction.parameters(e.g.,temperature,time an. hydrogen.pressure)is summarized an. critically discussed from a green.an. sustain.ble perspective usin. efficien.y in.icators(e.g.,yields,selectivity,turn.ver frequen.ies an. catalysts lifetime).Special atten.ion.has been.given.to the chemical tran.formation. occurrin. to iden.ify key descriptors to tun. the selectivity toward target products by man.pulatin. the reaction.con.ition. an. the structures of the ***,the challen.es an. future research goals to develop n.vel an. holistic n.tural oil biorefin.ries are *** a result,this critical review provides the readership with appropriate in.ormation.to selectively con.rol the tran.formation.of n.tural oils in.o either biofuels an./or value-added *** n.w flexible vision.can.help pave the wave to suit the presen. an. future market n.eds.

关键词： n.tural oil Deoxygen.tion Con.rollable selectivity Biofuels Fatty alcohols

Evaluation.of maize root growth an. gen.me-wide association.studies of root traits in.respon.e to low n.trogen.supply at seedlin. emergen.e

在线全文

学校读者我要写书评

暂无评论

The Crop Journ.l 2021年第4期9卷 794-804页

作者： Xichao Sun.wei Ren.Pen. Wan. Fan.un.Chen.Lixin. Yuan.Qin.chun.Pan.Guohua Mi College of Resources an. En.iron.en.al Scien.es National Academy of Agriculture Green DevelopmentKey Laboratory of Plant-Soil InteractionsMinistry of EducationChina Agricultural UniversityBeijing 100193China Agro-En.iron.en.al Protection.In.titute Ministry of Agriculture and Rural AffairsTianjin 300191China

n.trogen.n. deficien.y is on. of the main.factors limitin. maize(Zea mays L.) productivity. Gen.tic improvemen. of root traits could improve n.trogen.use efficien.y. An.association.pan.l of 461 maize in.red lin.s was assayed for root growth at seedlin. emergen.e un.er high-n.trate(Hn. 5 mmol L^(-1))an. low-n.trate(Ln. 0.05 mmol L^(-1)) con.ition.. Twen.y-on. root traits an. three shoot traits were measured. Un.er Ln.con.ition., the root-to-shoot ratio, root dry weight, total root len.th, axial root len.th,an. lateral root len.th on.the primary root were all in.reased. Un.er Ln.con.ition., the heritability of the plan. traits ran.ed from 0.43 to 0.82, a ran.e much wider than.that of 0.27 to 0.55 observed un.er Hn.con.ition.. The pan.l was gen.typed with 542,796 high-den.ity sin.le-n.cleotide polymorphism(Sn.) markers. Totally 328 sign.fican. Sn. markers were iden.ified usin. either mixed lin.ar model(MLM) or gen.ral lin.ar model an.lysis, with 34 detected by both methods. In.the 100-kb in.ervals flan.in. these Sn. markers, four can.idate gen.s were iden.ified. Un.er Ln.con.ition., the protoporphyrin.gen.IX oxidase 2 gen. was associated with total root surface area an. the DELLA protein.en.odin. gen. was associated with the len.th of the visible lateral root zon. of the primary root. Un.er Hn.con.ition., a histon. deacetylase gen. was associated with plan. height. Un.er both Ln.an. Hn.con.ition., the gen. en.odin. MA3 domain.con.ain.n. protein.was associated with the first whorl crown.root n.mber. The phen.typic an. gen.tic in.ormation.from this study may be exploited for gen.tic improvemen. of root traits aimed at in.reasin. n.E in.maize.

关键词： Gen.me-wide association.study(GWAS) n.trogen Maize Root

~1H-magn.tic reson.n.e spectroscopy screen.n. for an.mals with acute cerebral in.raction.suitable forthrombolytic therapy

在线全文

学校读者我要写书评

暂无评论

n.ural Regen.ration.Research 2007年第5期2卷 281-285页

作者： Li Yi Haiou Zhan. Hao Lei Li wei Departmen. of n.urology Peking University Shenzhen Hospital Shenzhen 518036 Guangdong Province China In.titute of Physics an. Mathematics the Chinese Academy of Science Wuhan 430074 Hubei Province China

BACKGROUn.： As a n.n.in.asive techn.que which can.provide comprehen.ive biological in.ormation. 1H-magn.tic reson.n.e spectroscopy （1H-MRS） may provide valuable referen.e data for irreversible recovery or reversible chan.es in.ischemic tissue after stroke. OBJECTIVE： To mon.tor an. evaluate the effect of the urokin.se thrombolytic therapy after experimen.al acute cerebral ischemia by 1H-MRS techn.logy an. in.estigate its adaptability. DESIGn. Ran.omly con.rolled an.mal study. SETTIn.S： Shen.hen.Hospital of Pekin. Un.versity an. n.tion.l Key Laboratory of Pattern.an. Atom ＆ Molecular Physics, Wuhan.Physics an. Mathematics In.titute, Chin.se Academy of Scien.e. MATERIALS： Eleven.healthy adult Sprague-Dawley （SD） rats, weighin. 260–300 g an. of both gen.ers, were supplied by Experimen.al An.mal Cen.er of Ton.ji Medical Collage, Huazhon. Un.versity of Scien.e an. Techn.logy [SCXK （e） 2004-007]. 4.7T supercon.uctin. n.clear magn.tic reson.n.e meter was provided by Brucker Compan.. METHODS： The experimen. was carried out in.Shen.hen.Hospital of Pekin. Un.versity an. n.tion.l Key Laboratory of Pattern.an. Atom ＆ Molecular Physics, Wuhan.Physics an. Mathematics In.titute, Chin.se Academy of Scien.e from August 2003 to December 2005. ① The rats were ran.omly divided in.o 30-min.te self-thrombo-embolism group （n.=6） an. 60-min.te self-thrombo-embolism group （n.=5）. Six rats in.30-min.te self-thrombo-embolism group were occluded with clot embolus for 30 min.tes an. 5 rats in.60-min.te self-thrombo-embolism group were occluded for 60 min.tes. 10 000 U/kg urokin.se was dissolved in.2 mL salin. an. the operation.lasted for 5 min.tes. ② 1H-MRS was performed before thrombolysis an. at 3 hours an. 24 hours after successful embolization. The metabolic chan.es of n.acetyl-L-aspartic acid （n.A）/phosphocreatin. （PCr）＋ creatin. （Cr）, cholin. phosphate （Cho）/PCr＋Cr an. lactic acid （Lac）/PCr＋Cr in.the region.of in.erests were an.lyzed. ③ The T2W image was con.ucted 24 hours after the thro

关键词： cerebral ischemia urokin.se thrombolysis therapy magn.tic reson.n.e imagin.

基于cAMP/PKA信号通路探讨红芪多糖影响糖尿病胃轻瘫大鼠钙稳态和能量代谢的作用机制

在线全文

学校读者我要写书评

暂无评论

中药药理与临床 2024年第8期40卷 56-60页

作者：安惠朱小利魏昭晖李荣科张磊苗琳琳万生芳甘肃中医药大学兰州730000 甘肃省中医方药挖掘与创新转化重点实验室兰州730000

目的:探究红芪多糖对糖尿病胃轻瘫(Diabetic gastroparesis,DGP)大鼠钙稳态和能量代谢的作用机制。方法:62只雄性Wistar大鼠随机分为正常对照组12只和造模组50只,采用小剂量多次注射链脲佐菌素+不规则饮食复制DGP模型。将成模大鼠随机... 详细信息

目的:探究红芪多糖对糖尿病胃轻瘫(Diabetic gastroparesis,DGP)大鼠钙稳态和能量代谢的作用机制。方法:62只雄性Wistar大鼠随机分为正常对照组12只和造模组50只,采用小剂量多次注射链脲佐菌素+不规则饮食复制DGP模型。将成模大鼠随机分为模型对照组、莫沙必利1.35 mg/kg组和红芪多糖50、100、200 mg/kg组,各给药组给予相应药物灌胃,正常对照组和模型对照组予等体积纯净水灌胃。观察大鼠一般情况,称体质量、检测随机血糖、胃排空率;HE染色观察大鼠胃窦组织病理改变;ELISA法检测胃窦组织中ATP、n.^(+)-K^(+)ATP酶、Ca^(2+)-Mg^(2+)ATP酶、钙离子(Ca^(2+))浓度;免疫组化和Western.blot法分别检测胃窦组织中环磷酸腺苷(cAMP)、蛋白激酶A(PKA)、钙调蛋白依赖蛋白激酶Ⅱ(CaMKⅡ)及其磷酸化的分布和蛋白表达。结果:与正常对照组相比,模型对照组大鼠体质量、胃排空率和胃窦组织中ATP、n.^(+)-K^(+)ATP酶和Ca^(2+)-Mg^(2+)ATP酶浓度、cAMP和PKA蛋白表达均显著降低(Pn.^(+)-K^(+)ATP酶和Ca^(2+)-Mg^(2+)ATP酶浓度、cAMP、PKA蛋白表达均明显升高(P<0.05或P<0.01),血糖、胃窦组织中Ca^(2+)浓度和CaMKII及其磷酸化蛋白表达均明显降低(P<0.05或P<0.01)。结论:HPS可以调节DGP大鼠钙稳态促进能量代谢,其机制可能与上调cAMP/PKA信号通路的表达,抑制CaMKII活性有关。

关键词：红芪多糖糖尿病胃轻瘫环磷酸腺苷/蛋白激酶A信号通路钙稳态能量代谢

Evaluatin. the methodology of studies con.ucted durin. the global COVID-19 pan.emic: A systematic review of ran.omized con.rolled trials

在线全文

学校读者我要写书评

暂无评论

Journ.l of In.egrative Medicin. 2021年第4期19卷 317-326页

作者： Men.-zhu Zhao Chen.Zhao Shuan.-shuan. Tu Xu-xu wei Hon.-cai Shan. Departmen. of Cardiology First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300381China n.tion.l Clin.cal Research Cen.er for Chin.se Medicin. Acupun.ture an. Moxibustion Tianjin 300381China In.titute of Basic Research in.Clin.cal Medicin. China Academy of Chinese Medical SciencesBeijing 100700China Editorial Departmen. of Journ.ls Tianjin University of Traditional Chinese MedicineTianjin 301617China Key Laboratory of Chin.se In.ern.l Medicin. of Min.stry of Education.an. Beijin. Dongzhimen Hospital Affiliated to Beijing University of Chinese MedicineBeijing 100700China In.ern.tion.l Eviden.e-based Research In.titute of Chin.se Medicin. Beijing University of Chinese MedicineBeijing 100029China

Backgroun.: The therapeutic eviden.e collected from well-design.d studies is n.eded to help man.ge the global pan.emic of the coron.virus disease 2019(COVID-19). Evaluatin. the quality of therapeutic data collected durin. this most recen. pan.emic is importan. for improvin. future clin.cal research un.er similar ***: To assess the methodological quality an. variability in.implemen.ation.of ran.omized con.rolled trials(RCTs) for treatin. COVID-19, an. to an.lyze the support that should be provided to improve data collected durin. an.urgen. pan.emic *** strategy: Pub Med, Excerpta Medica Database, Chin. n.tion.l Kn.wledge In.rastructure, Wan.an.,an. Chon.qin. VIP, an. the preprin. repositories in.ludin. Social Scien.e Research n.twork an. Med Rxiv were systematically searched, up to September 30, 2020, usin. the keywords "coron.virus disease 2019(COVID-19)," "2019 n.vel coron.virus(2019-n.Co V)," "severe acute respiratory syn.rome-related coron.virus-2(SARS-Co V-2)," "n.vel coron.virus pn.umon.a(n.P)," "ran.omized con.rolled trial(RCT)" an. "ran.om."In.lusion.criteria: RCTs studyin. the treatmen. of COVID-19 were eligible for *** extraction.an. an.lysis: Screen.n. of published RCTs for in.lusion.an. data extraction.were each con.ucted by two researchers. An.lysis of gen.ral in.ormation.on.COVID-19 RCTs was don. usin. descriptive statistics. Methodological quality was assessed usin. the risk-of-bias tools in.the Cochran. Han.book for Systematic Reviews of In.erven.ion.(Version.5.1.0). Variability in.implemen.ation.was assessed by comparin. con.isten.y between.RCT reports an. registration.***: A total of 5886 COVID-19 RCTs were iden.ified. Eighty-on. RCTs were fin.lly in.luded, of which,45 had registration.in.ormation. Methodological quality of the RTCs was n.t optimal due to deficien.ies in.five main.domain.: allocation.con.ealmen., blin.in. of participan.s an. person.el, blin.in. of outcome assessmen., in.omp

关键词： COVID-19 Ran.omized con.rolled trial Therapeutic eviden.e Methodology Systematic review