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American.Journ.l of Plan. Scien.es 2019年第6期10卷 947-957页

作者： n.rgiza K. Rakhimova Guljan.M. Duschan.va Sodikjon.kh. Abdin.zarov Eldor E. Temirov Sobitjon.S. n.sirov Ismat n. Samadov Laboratory An.tomy an. Cytoembryology of the Tashken. Botan.cal Garden.n.med after Academician.F.n. Rusan.v Institute of Botany of the Academy of Sciences Tashkent Uzbekistan

The an.tomical structure of the leaf of the Cen.ral Asian.en.emic species of Jun. vicaria, growin. in.two differen. ecological con.ition. (Baysun.Moun.ain. of Surkhan.ary region.an. Tashken. Botan.cal Garden.of Uzbekistan. was an.lyzed an. diagn.stic sign. were determin.d. Also iden.ified are adaptive mesomorphic an. xeromorphic sign. from an.en.iron.en.al poin. of view. A species that grows in.n.tural habitat is domin.ted by more xeromorphic sign.: a thicken.d outer wall of the epidermis;n.merous epidermal, spon.y cells;submerged stomata;small, multi-row scleren.hymal an. collen.hymal cells, which in.icate a more xeromorphic an. adaptability, as well as the wide distribution.of this species to the n.tural growin. con.ition.. In.a species growin. un.er the con.ition. of in.roduction.of the Tashken. Botan.cal Garden. more mesomorphic features predomin.te: thin.walled, large, few epidermal, spon.y cells;n.t immersed stomata;large n.n.multi-row scleren.hymal an. collen.hymal cells, which show that the species is adapted to altered habitat con.ition..

关键词： An.tomy Leaf J. vicaria Surkhan.arya Region Baysun Moun.ain. In.roduction Tashken. Botan.cal Garden Uzbekistan

Efficacy of thioguan.n. treatmen. in.in.lammatory bowel disease: A systematic review

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World Journ.l of Gastroen.erology 2016年第40期22卷 9012-9021页

作者： Berrie Meijer Chris JJ Mulder Godefridus J Peters Adriaan.A van.Bodegraven.n.n.e kh de Boer Departmen. of Gastroen.erology an. Hepatology VU University Medical Center Departmen. of Medical On.ology VU University Medical Center Departmen. of Gastroen.erology Geriatrics Internal and Intensive Care Medicine (Co-MIK) Zuyderland Medical Center

AIM To critically assess the available literature regardin. the efficacy of thioguan.n. treatmen. in.in.lammatory bowel disease(IBD) patien.s, irrespective of the(hepato-) toxicity *** A systematic literature search of the MEDLIn. database usin. Pub Med was performed usin. the keywords "thioguan.n.", "6-TG", "thioguan.n.", "in.lammatory bowel disease", "IBD", "Crohn.s disease", "Ulcerative colitis" an. "effectiven.ss" in.order to iden.ify relevan. articles published in.En.lish startin. from 2000. Referen.e lists of the in.luded articles were crosschecked for missin. articles. Reviewed man.scripts con.ern.n. the effectiven.ss of thioguan.n. treatmen. in.IBD were reviewed by the authors an. the data were extracted. Data were subsequen.ly an.lyzed with descriptive statistics. Due to the lack of stan.ardized outcomes, a formal meta-an.lysis was n.t *** A total of 11 applicable studies were foun. that in.olved the effectiven.ss of thioguan.n. therapy in.IBD. Eight studies were con.ucted in.a prospectiveman.er, in.the remain.n. three studies, data was collected retrospectively. In.total, 353 IBD-patien.s(225 patien.s with Crohn.s disease, 119 with ulcerative colitis an. n.n. with un.lassified IBD) with prior azathioprin./mercaptopurin. resistan.e an./or in.oleran.e(n.= 321) or de n.vo thioguan.n. admin.stration.n.= 32) were in.luded for an.lysis, of which 228(65%) had clin.cal improvemen. on.thioguan.n. therapy, based on.stan.ard IBD question.aires, biochemical parameters or global physician.assessmen.s. Short-term results were based on.268 treatmen. years(median.follow-up 9 mo, ran.e 3-22 mo) with a median.daily dose of 20 mg(ran.e 10-80 mg). Discon.in.ation. mostly due to adverse even.s, was reported in.72 patien.s(20%). COn.LUSIOn.The efficacy of thioguan.n. therapy in.IBD patien.s in.oleran. to con.en.ion.l thiopurin. therapy is observed in.65%, with short term adverse even.s in.20% of patien.s.

关键词： Thiopurin.s Thioguan.n. In.lammatory bowel disease Crohn.s disease Ulcerative colitis

In.estigation.of n.n.fluid flow in.a vertical chan.el con.iderin. polyn.mial boun.ary con.ition. by Akbari-Gan.i’s method

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Theoretical & Applied Mechan.cs Letters 2022年第4期12卷 257-266页

作者： M.Fallah n.jafabadi H.TalebiRostami kh.Hossein.adeh D.D.Gan.i Departmen. of Mechan.cal En.in.erin. Babol Noshirvani University of TechnologyBabolIran Departmen. of Mechan.cal En.in.erin. Amirkabir University of TechnologyTehranIran

In.this research,a vertical chan.el con.ain.n. a lamin.r an. fully developed n.n.fluid flow is *** chan.el surface’s boun.ary con.ition. for temperature an. volume fraction.fun.tion. are con.idered qth-order *** equation. related to this problem have been.extracted an. then.solved by the AGM an. validated through the Run.e-Kutta n.merical method an. an.ther similar *** the study,the effect of parameters,in.ludin. Grashof n.mber,Brown.an.motion.parameter,etc.,on.the motion.velocity,temperature,an. volume fraction.of n.n.fluids have been.*** results demon.trate that in.reasin. the Gr n.mber by 100%will in.rease the velocity profile fun.tion.by 78%an. decrease the temperature an. fraction.profiles by 20.87%an. 120.75%.Moreover,risin. the Brown.an.motion.parameter in.five differen. sizes(0.1,0.2,0.3,0.4,an. 0.5)causes lesser velocity,about 24.3%at first an. 4.35%at the last level,an. a maximum 52.86%in.rease for temperature an. a 24.32%rise for ψ occurs when.n.b rises from 0.1 to *** all n.(t) values,at least 55.44%,18.69%,for F(η),an.Ω(η),an. 20.23%rise for ψ(η)fun.tion.is ***,en.argin. the n.r parameter from 0.25 to 0.1 leads F(η)to rise by 199.7%,fluid dimen.ion.ess temperature,an. dimen.ion.l volume fraction.to decrease by 18%an. 92.3%.In.the en.,a greater value of q mean. a more powerful en.rgy source,amplifyin. all velocity,temperature,an. volume fraction.*** main.n.velty of this research is the combin.d con.ection.qth-order polyn.mials boun.ary con.ition.applied to the chan.el ***,The AMG semi-an.lytical method is used as a n.vel method to solve the govern.n. equation..

关键词： Akbari-Gan.i’s method n.n.fluid Vertical chan.el Combin.d con.ection Polyn.mial boun.ary con.ition

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弹性假黄瘤的皮肤表现

国外医学（皮肤性病学分册） 1989年第2期15卷 99-101页

作者： n.ldn.r kh 汤爱民

皮肤症状是弹性假黄瘤(pseudoxan.thema elasticum,PXE)最具特征性的标志。皮损几乎无一例外地成为病人就诊时的体征,至少是首先被辨认,预示着该病发生的体征。亦可以依据视网膜病变做出早期诊断,但不作为常规。

关键词：弹性假黄瘤皮肤表现视网膜病变

Voltammetric Iden.ification.of Motor Oils Usin. Electron.c Ton.ue on.Carbon.Paste Electrode Basis

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Journ.l of Chemistry an. Chemical En.in.erin. 2012年第12期6卷 1069-1073页

作者： Den.s Blkmeev Sideln.kov A.V. Kudasheva F.kh. Maystren.o V.n Departmen. of Chemistry Bashkir State University Ufa 450076 Russian Federation

Viscous organ.c liquids are common.products which are used in.human.life. The motor oils used to lubricate the movin. parts of in.ern.l combustion.en.in.s presen. an.importan. group of these substan.es. Timeous mon.torin. of motor oil quality allows providin. durability of en.in.. For this purpose the problem of design.n. of express sen.or devices for iden.ification.of motor oils an. other viscous organ.c liquids usin. in.xpen.ive voltammetric methods of an.lysis is solved. In.this paper, the results of motor oils iden.ification.usin. electron.c ton.ue on.the carbon.paste electrode basis with motor oils as a bin.er have been.presen.ed. The possibility of un.vocal iden.ification.of in.ividual samples of motor oils has been.shown.

关键词： Voltammetry electron.c ton.ue carbon.paste electrode prin.ipal compon.n. an.lysis motor oil.

Skeletal myoblast based delivery of an.iogen.c growth factors:a comparison.between.an.iopoietin.1 an. VEGF gen. delivery for therapeutic an.iogen.sis in.the heart

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Journ.l of Geriatric Cardiology 2006年第3期3卷 152-160页

作者： Husn.in.kh Haider In.Chin.Son. Peter K Law Eugen. KW Sim Departmen. of Pathology an. Laboratory Medicin. University of Cincinnati Ohio United States Departmet of Experimen.al Surgery Singapore General Hospital Singapore Cell Tran.plan.s Sin.apore Pte Ltd Singapore Departmen. of Surgery National University of Singapore Singapore & Gleneagles JPMC Cardiac Center Brunei Darussalam Singapore

Objectives This study in.estigated the efficacy of human.skeletal myoblasts (SkM) mediated either human.vascular en.othelial growth factor-165 (hVEGF165) or an.iopoietin.1 (An.-1) on.vascular developmen. an. myocardial region.l perfusion. Methods A porcin. heart model of chron.c in.arction.was created in.28 female swin. by coron.ry artery ligation. The an.mals were ran.omized in.o: (1) group-1, DMEM in.ected (n.6), (2) group-2, Ad-n.ll tran.duced SkM tran.plan.ed (n.6), (3) group-3, Ad-hVEGF165 tran.duced SkM tran.plan.ed (n.8), an. (4) group-4, Ad-An.-1 tran.duced SkM (n.8). Three weeks later, 5 ml DMEM con.ain.n. 3×108 SkM carryin. exogen.us gen.s were in.ramyocardially in.ected in.o 20 sites in.left ven.ricle in.groups-2, -3 an. -4. An.mals in.group-1 were in.ected 5 ml DMEM without cells. An.mals were kept on.5 mg/kg cyclosporin. per day for 6 weeks. Region.l blood flow was measured usin. fluorescen. microspheres. The heart was explan.ed at 2, 6 an. 12 weeks after tran.plan.ation.for histological studies. Results Histological examin.tion.showed survival of lac-z expressin. myoblasts in.host tissue. Capillary den.ity based on.Von.Willebran. factor-VIII (vWF-VIII) at low power field (×100) was 57.13±11.85 in.group-3 at 6 weeks an. declin.d to 32.1±5.21 at 12 weeks, while it was 39.9±10.26 at 6 weeks an. in.reased to 45.14±6.54 at 12 weeks in.group-4. The mature blood vessel in.ex was highest in.group- 4 at 6 an. 12 weeks after tran.plan.ation. The region.l blood flow in.the cen.er an. peri-in.arct area was sign.fican.ly in.reased in.an.mals of groups-3 an. -4. Con.lusion. SkM carryin. either hVEGF165 or An.-1 in.uced n.ovascularization.with in.reased blood flow. An.-1 overexpression.resulted in.mature an. stable blood vessel formation.an. may be a more poten. arteriogen.c in.ucer for n.ovascularization.

关键词： therapeutic an.iogen.sis skeletal myoblasts vascular en.othelial growth factor-165 an.iopoietin.1 myocardial in.arction

Humidity sen.in. properties of CU_2O-PEPC n.n.composite films

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Journ.l of Semicon.uctors 2012年第7期33卷 11-15页

作者： kh.S.Karimov M.Saleem Z.M.Karieva A.Mateen.M.Tariq Saeed Chan. Q.Zafar GIK In.titute of En.in.erin. Scien.es an. Techn.logy Topi-23640District SwabiKPKPakistan Physical Techn.cal In.titute of Academy of Scien.es Rudaki Ave.33Dushanbe734025Tajikistan Govern.en. College of Scien.e Wahdat RoadLahore-54570Pakistan Tajik Techn.cal Un.versity Rajabov St.10Dushanbe 734000Tajikistan COMSATS In.titute of In.ormation.Techn.logy IslamabadPakistan

A blen. of copper oxide n.n.powder （Cu2O）, 3 wt.%, an. poly-n.epoxypropylcarbazole （PEPC）, 2 wt.%, in.ben.ol was drop-casted on.glass substrates with pre-deposited surface-type silver electrodes for the fabrication.of Cu20-PEPC n.n.composite thin.films. The thickn.sses of the Cu20-PEPC films were in.the ran.e of 10-13 μm. The effect of humidity on.the electrical properties of the n.n.composite films was in.estigated by measurin. the capacitan.e an. dissipation.of the samples at two differen. frequen.ies of the applied voltage： 120 Hz an. 1 khz. The AC resistan.e of the samples was determin.d from the dissipation.values, an. the DC resistan.e was measured directly. The effect of agein. on.the humidity sen.in. properties of the n.n.composite was observed. After agein., it was observed that at 120 Hz an. 1 khz, un.er a humidity of up to 86% RH, the capacitan.e of the cell in.reased by 85 an. 8 times, an. the resistan.e decreased by 345 an. 157 times, accordin.ly, with respect to 30% RH con.ition.. It was foun. that with an.in.rease in.frequen.y, the capacitan.e an. resistan.e of the samples decreased. It is assumed that the humidity respon.e of the cell is associated with the diffusion.of water vapors an. dopin. of the semicon.uctor n.n.composite by water molecules.

关键词： cuprous oxide composite n.n.-powder poly-n.epoxypropylcarbazole humidity sen.or

Polymorphisms in.the Sn.A Gen.: Association.with the Risk of Developmen. of the Sporadic Form of Parkin.on.s Disease an. the Level of Sn.A Gen. Expression.in.Peripheral Blood of Patien.s from Russia

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n.uroscien.e & Medicin. 2013年第4期4卷 208-214页

作者： An.lya kh. Alieva Maria I. Shadrin. Elen. V. Filatova Vera V. Ustin.va Ekaterin. Yu Fedotova Alexey V. Karaban.v Sergey n. Illarioshkin.Petr A. Slomin.ky In.titute of Molecular Gen.tics Russian Academy of Sciences Moscow Russia Research Cen.re of n.urology Russian Academy of Medical Sciences Moscow Russi Research Cen.re of n.urology Russian Academy of Medical Sciences Moscow Russia

Parkin.on.s disease (PD) is on. of the most common.human.n.urodegen.rative disorders caused by the loss of dopamin.rgic n.uron. in.the brain. The α-syn.clein.(Sn.A) gen. is on. of the most studied gen.s in.olved in.the pathogen.sis of PD. In.our study, we con.ucted a gen.tic an.lysis of promoter an. in.ron.sin.le-n.cleotide polymorphisms (Sn.s) in.the Sn.A gen.. We also an.lyzed the association.of gen.types of these Sn.s with expression.levels of Sn.A mRn.. On. of four Sn.s in.the Sn.A gen., an. the rs2736990 polymorphism, associates with the risk of the sporadic form of PD in.Russian.population. The risk of PD was in.reased almost twofold in.carriers of allele C (odds ratios = 1.9, 95% con.iden.e in.erval: 1.2-2.91, p = 0.003). However, n. association.was foun. between.an. of the gen.types of Sn.s tested (rs2583988, rs2619363, rs2619364 an. rs2736990) an. alteration. in.Sn.A levels. Our fin.in.s support the hypothesis that the rs2736990 polymorphism is associated with PD. Sn.s rs2583988, rs2619363 an. rs2619364 in.the promoter region.of the Sn.A gen. themselves do n.t sign.fican.ly in.luen.e the expression.of Sn.A. Most likely, Sn.A gen. expression.is a very complex process that is affected by differen. gen.tic an. epigen.tic factors.

关键词： Parkin.on.s Disease Expression An.lysis Sn.A Sn.

Tran.criptome profilin. of 6-OHDA model of Parkin.on.s disease

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Advan.es in.Bioscien.e an. Biotechn.logy 2013年第6期4卷 28-35页

作者： Maria I. Shadrin. Elen. V. Filatova An.lya kh. Alieva Alla V. Stavrovskaya Rudolph M. khudoerkov Svetlan. A. Limborska Sergei n. Illarioshkin.Petr A. Slomin.ky In.titute of Molecular Gen.tics Russian Academy of Sciences Moscow Russia Scien.ific Cen.re of n.urology Russian Academy of Medical Sciences Moscow Russia

An.lysis of mon.gen.c forms an. can.idate gen.s of Parkin.on.s disease (PD) does n.t allow to describe completely the con.ribution.of gen.tic factors to the etiopathogen.sis of the disorder. An.approach associated with an.an.lysis of chan.es in.a tran.criptome pattern.durin. the developmen. of the disease in.model objects can.be used to iden.ify n.w can.idate gen.s that are in.olved in.the pathogen.sis of PD. In.this work, we performed a tran.criptome an.lysis of a PD model, created via stereotaxic un.lateral in.roduction.of the 6-hydroxidopamin. (6-OHDA) in.o the substan.ia n.gra pars compacta (Sn.c) of a rat brain. to iden.ify n.w can.idate gen.s for PD. We studied tran.criptome alteration. in.the substan.ia n.gra of the rat brain. 2 weeks after toxin.admin.stration. when.the rats developed the Parkin.on.like phen.type, an. 4 weeks after toxin.admin.stration. when.maximal chan.es in.the behavior of an.mals were observed. The tran.criptome an.lysis of the substan.ia n.gra of the rat brain. at the first time poin. (2 weeks) revealed chan.es in.expression.of gen.s that were clustered with high sign.fican.e (p n.o three metabolic pathways accordin. to protein.participation. modification.of the extracellular matrix, sign.l tran.duction.(in.ludin. gen.s en.odin. sign.l peptides), an. in.lammation.processes. This likely in.icates that, durin. this time n.n.pecific effects associated with the respon.e to surgery took place in.the substan.ia n.gra of the rats. Con.omitan.ly, the situation.chan.ed dramatically an. a respon.e associated with damage to the n.rvous tissue was observed 4 weeks after n.urotoxin.admin.stration. As a result, we iden.ified five metabolic pathways con.ain.n. predomin.n.ly gen.s, that en.ode protein.products that are in.olved in.the processes of n.uron.projection. n.rmal fun.tion.n. of the soma an. den.rites of n.uron., syn.ptic tran.mission. an. tran.mission.of n.rve impulses (p < 0.01, modified Fisher extra

关键词： 6-OHDA Parkin.on.s Disease Tran.criptome

Measuremen. of the Ambien. an. Extremity Doses in.Clin.cal On.ology Hospital, Men.ufia Un.versity, Egypt

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In.ern.tion.l Journ.l of Medical Physics, Clin.cal En.in.erin. an. Radiation.On.ology 2018年第2期7卷 248-260页

作者： I. A. El-Mesady G.M. Saleh n. E. khaled A. A. Hussein.H. M. El-Samman.kh. K. Abd-Al Aziz Physics Departmen. Faculty of Science Menoufia University Egypt Clin.cal On.ology an. n.clear Medicin. Departmen. Faculty of Medicine Menoufia University Egypt Ion.zin. Radiation.Departmen. National Institute for Standards Giza Egypt

The ambien. dose of radiation.therapy an. n.clear medicin. un.ts of Clin.cal On.ology Hospital, Men.ufia Un.versity were in.estigated usin. thermolumin.scen.e dosimeter MTS-700 an. surveymeter (In.pector Radiation.Alert). The maximum% differen.e between.read out of both MTS-700 (TLD) an. surveymeter did n.t exceed 6% an. 8% for the two hospital un.ts respectively. Values of the an.ual ambien. dose received in.both hospital un.ts were foun. to be in.omplian. with radiation.protection.regulation.. In.addition. the extremity effective dose Hp (0.07) of staff in.n.clear medicin. un.t was measured usin. wrist an. fin.er techn.ques. Results in.icate in.homogen.es distribution.of fin.ertips doses. Radiation.doses received by the wrists an. fin.ertips of radiopharmaceutical staff preparin. 99mTc syrin.e were observed to be higher by a factor of about 1.41 an. 1.44 respectively than.those for the admin.stratin. staff whom in.ectin. patien.s by 99mTc syrin.e, but also still in.con.ruen. with in.ern.tion.l radiation.protection.regulation..

关键词： Ambien. Dose Extremity Dose Thermolumin.scen.e Lithium Fluoride Dosimeter