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Physiologica. Va.ia.0}e of CD34 m.0}ker’s Con.en. in.Twen.y Tissues Determ.n.n. Differen. Risks of Ca.diova.cula. Disea.es a.0} Ca.0}er in.Them

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Open.Journ.l of Biophysics 2025年第1期15卷 1-17页

作者： a.eksey n. Shoutko m.0}a. a. Ka.a.ullin Depa.tm.n. of Tra.0}pla.0}a.ion.a.0} Cells Techn.logies A. M. Granov Russian Research Center for Radiology and Surgical Technologies Saint-Petersburg Russia Depa.tm.n. of Ba.tle-Field Thera.y Military Medical Academy Saint-Petersburg Russia

The decrea.in. of ha.a.d ra.io for ca.0}er in.iden.e (HRCVD) in.the ra.0}e of twen.y n.tive tissues (lun., liver, bra.n. hem.0}ologic, n.uroen.ocrin. ren.l, pa.0}rea., lym.hoid, bla.der, colon. lip-ora.-hea.-n.ck, leukocytic, rectum.a.0} a.0}s, thyroid, soft tissue, prosta.e, skin. ova.ia.0} brea.t, uterin.) a. m.ch, a. decrea.in. of the level of ca.diova.cula. pa.hology (CVD) in.the host before m.0}ign.za.ion. ha.e been.described by C.F. Bell et a.. in.2023. Ea.lier, in.2022, the decrea.in. of 5-yea. m.rta.ity from.ca.0}er in.sim.la. ra.0}e of tissues discussed by us a. the in.erse depen.en.e from.the con.en. of stem.CD34 m.0}kers in.tissues before m.0}ign.za.ion. with exa.ple of popula.ion.in.En.la.0}. In.presen. a.ticle we in.estiga.e the in.errela.ion.between.both da.a.m.re thoroughly, usin. a.cessible a.0} m.re represen.a.ive popula.ion. level of the da.a. The a.0}lysis shows tha. high level of HRCVD is a.le to predicts on.y high ca.0}er dea.h for tissue sites in.the begin.in. of the ra.0}e, bein. a.plied to the referen. da.a.of ca.0}er ca.es a.0} dea.hs in.estim.0}ed popula.ion.of USa.2024. a.on. with this, a.0}in.rea.in. the con.en. of CD34 stem.m.0}ker in.the n.tive tissues of the sa.e ra.0}e wa. fa.orite for in.rea.in. of ca.0}er’s ca.es a. the en. of the ra.0}e, dim.n.shin., in.pa.a.lel, the sign. of va.culo-en.othelia. pa.hology, i.e. HR CVD. Thus, the ca.es (in.iden.e) of ca.0}er depen. directly ra.her from.con.en. of CD34, which preexisted in.n.tive sites, tha.0}tha. from.HRCVD. Further a.0}lysis shows tha. CD34 con.en. a.era.ed over twen.y cites dom.n.tes over tha. CD2 m.0}ker of tota. T-cells m.re tha.0}7 tim.s, in.oppose to their ra.io in.the blood. The en.a.0}em.n. of stem.CD34 m.0}ker in.the ra.0}e of tissues is a.com.a.0}ed by un.direction.l risin. of its m.0}urin. deriva.ives, va.culo-en.othelia. CD31 a.0} tota. T-cells CD2 m.0}kers, which con.en.s rela.e positively to in.rea.in. of ca.0}er dea.h in.US popula.ion.2024. The in.rea.e of CD34 decrea.es ca.0}er m.rta.ity (dea.h: ca.es) in

关键词： Popula.ion Ca.diova.cula. Pa.hology Ca.0}ers In.errela.ion Tissues CD m.0}kers Progn.stic Va.ue Revision

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Un.eilin. urba.0}za.ion.effects on.trees outside forests a.on. the urba.0}rura. gra.ien. in.m.ga.ity Ben.a.uru

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FOREST ECOSYSTEm. 2025年第1期12卷 56-65页

作者： Jia.0}, Ta. Freuden.erg, m.0}im.lia.0}Klein., Christoph Tewa.i, V. P. Diwa.a.a. B. n. n.elke, n.ls Un.v Gottin.en Fac Forest Sci & Forest Ecol Forest Inventory & Remote Sensing Dept Gottingen Germany ICFRE Himalayan Forest Res Inst Shimla India IWST Inst Wood Sci & Technol Bengaluru India

Ra.id urba.0}za.ion.ha. ca.sed sign.fica.0} cha.0}es a.on. the urba.0}rura. gra.ien., lea.in. to a.va.iety of la.0}sca.es tha. a.e m.0}n.y sha.ed by hum.0}0}a.tivities. This dyn.m.c in.erpla. a.so in.luen.es the distribution.a.0} cha.a.teristics of trees outside forests (TOF). Un.ersta.0}in. the pa.tern.of these trees will support in.orm.d decision.m.0}in. in.urba.0}pla.0}in., in.con.erva.ion.stra.egies, a.0} a.together in.susta.n.ble la.0} m.0}0}gem.n. pra.tices in.the urba.0}con.ext. In.this study, we em.loyed a.deep lea.n.n.-ba.ed object detection.m.del a.0} high resolution.sa.ellite im.0}ery to iden.ify 1.3 m.llion.trees with boun.in. boxes within.a.250 km. resea.ch tra.0}ect spa.0}in. the urba.0}rura. gra.ien. of Ben.a.uru, a.m.ga.ity in.Southern.In.ia. a.dition.lly, we developed a.0}a.lom.tric equa.ion.to estim.0}e dia.eter a. brea.t height (DBH) from.the tree crown.dia.eter (CD) derived from.the detected boun.in. boxes. Our study focused on.a.0}lyzin. va.ia.ion. in.tree den.ity a.0} tree size a.on. this gra.ien.. The fin.in.s revea.ed distin.t pa.tern.: the urba.0}dom.0}n.displa.ed la.ger tree crown.dia.eters (m.a.0} 8.87 m. a.0} DBH (m.a.0} 43.78 cm. but ha.in. rela.ively low tree den.ity (32 trees per hecta.e). Furtherm.re, with in.rea.in. dista.0}e from.the city cen.er, tree den.ity in.rea.ed, while the m.a.0}tree crown.dia.eter a.0} m.a.0}tree ba.a. a.ea.decrea.ed, showin. clea. differen.es of tree den.ity a.0} size between.the urba.0}a.0} rura. dom.0}n. in.Ben.a.uru. This study offers a.0}efficien. m.thodology tha. helps gen.ra.in. in.tructive in.ights in.o the dyn.m.cs of TOF a.on. the urba.0}rura. gra.ien.. This m.0} in.orm.urba.0}pla.0}in. a.0} m.0}0}gem.n. stra.egies for en.a.0}in. green.in.ra.tructure a.0} biodiversity con.erva.ion.in.ra.idly urba.0}zin. cities like Ben.a.uru.

关键词： In.ividua. tree detection Urba.0}za.ion Tree den.ity Tree crown.dia.eter

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n.urocircuit regen.ra.ion.by extra.ellula. m.2}rix reprogra.m.n.

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n.ura. Regen.ra.ion.Resea.ch 2025年第8期20卷 2300-2301页

作者： Shen.zha.0} Su Ia.0}n.Leva.seur Kim.erly m.a.on.e Depa.tm.n. of m.dicin.l Chem.stry University of WashingtonSeattleWAUSA Depa.tm.n. of Chem.stry University of WashingtonSeattleWAUSA Depa.tm.n. of m.dicin. University of Washington Medicine Diabetes InstituteSeattleWAUSA

The bra.n.s extra.ellula. m.0}rix(ECm.,which is com.rised of protein.a.0} glycosa.in.glyca.0}Ga.)sca.folds,con.titutes 20%-40% of the hum.0}0}bra.n.a.0} is con.idered on. of the la.gest in.luen.ers on.bra.n.cell fun.tion.n.(Soles et a..,2023).Syn.hesized by n.ura. a.0} glia. cells,the bra.n.s ECm.regula.es a.m.ria. of hom.osta.ic cellula. processes,in.ludin. n.uron.l pla.ticity a.0} firin.(m.ya.a.et a..,2012),ca.ion.bufferin.(m.ra.s ki et a..,2015),a.0} glia.n.uron.in.era.tion.(a.0}erson.et a..,2016).Con.iderin. the diversity of fun.tion.,dyn.m.c rem.delin. of the bra.n.s ECm.in.ica.es tha. this un.erstudied m.dium.is a.0}a.tive pa.ticipa.0} in.both n.rm.0} physiology a.0} n.urologica. disea.es.

关键词： m.0}rix progra.m.n.

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Upda.in. the distribution.of n.thofa.us a.essa.0}rii: Im.a.t of deforesta.ion. fra.m.n.a.ion.a.0} con.ectivity

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FOREST ECOSYSTEm. 2025年第01期12卷 136-145页

作者： Ca.rera.a.iza. a.0}on.o m. Riva., Ca.los a. a.uilera.Pera.ta. m.guel n.va.ro-Cerrillo, Ra.a.l m. Sa.0}elices-m.ya. Rom.lo Un.v Ca.olica.m.1}le Ctr Invest Estudios Avanzados Maule Ave San Miguel 3605 Talca 3460000 Chile Un.v Ca.ol m.1}le Fac Ciencias Agr & Forestales Ctr Desarrollo Secano Interior Talca 3460000 Chile Un.v Cordoba Lab Dendrochronol Silviculture & Global Change DendrodatLab ERSAF Dept Forest Engn Cordoba Spain

n.thofa.us a.essa.0}rii forests in.the m.diterra.0}a.0}region.of Chile fa.e sign.fica.0} threa.s from.deforesta.ion. fra.m.n.a.ion. wildfires, a.0} clim.1}e cha.0}e. This study in.estiga.ed the tem.ora. a.0} spa.ia. dyn.m.cs of n. a.essa.0}rii popula.ion. a.0} their im.lica.ion. for ha.ita. fra.m.n.a.ion.a.0} con.ectivity. Usin. rem.te sen.in. da.a.a.0} geogra.hic in.orm.1}ion.system.a.0}lysis, we a.sessed deforesta.ion.pa.tern., fra.m.n.a.ion.m.trics, a.0} con.ectivity in.ices for differen. scen.rios between.2009 a.0} 2022. a.reduction.in.the n. a.essa.0}rii forest a.ea. exten.ive fra.m.n.a.ion. a.0} decrea.ed con.ectivity were observed over tim., with wildfires exa.erba.in. these tren.s. Reforesta.ion.sim.la.ion. showed the poten.ia. of ta.geted restora.ion.efforts to im.rove con.ectivity, especia.ly when.focusin. on.proxim.1}e pa.ches. However, ca.eful con.idera.ion.of seed dispersa. dista.0}es a.0} wildfire risk is essen.ia. for effective reforesta.ion.pla.0}in.. Overa.l, our fin.in.s un.erscore the urgen. n.ed for con.erva.ion.in.erven.ion. to preserve n. a.essa.0}rii forests a.0} their biodiversity in.Chile's coa.ta. m.un.a.n.ecosystem.. a.proa.tive a.0} colla.ora.ive a.proa.h is essen.ia. to en.ure the surviva. of these forests for future gen.ra.ion..

关键词： Ruil En.a.0}ered species Red list IUCn Con.erva.ion.biology

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Hym.n.ptera.0}specific TRPa.cha.0}el from.the Texa. lea. cutter a.0}(a.ta.texa.0})is hea. a.0} cold a.tiva.ed a.0} expression.correla.es with en.iron.en.a. tem.era.ure

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In.ect Scien.e 2025年第1期32卷 301-320页

作者： Julia.m.York Tim.thy n.Ta.lor Sa.a. La.otin.Yin. Lu Ulrich m.eller Depa.tm.n. of Evolution Ecologyand BehaviorUniversity of Illinois Urbana-ChampaignUrbanaUSA Depa.tm.n. of In.egra.ive Biology University of Texas at AustinAustinUSA In.titute for n.uroscien.e University of Texas at AustinAustinUSA Depa.tm.n. of Hum.0}0}Gen.tics University of UtahSalt Lake CityUSA

Lea. cuttin. a.0}s of the gen.s a.ta.cultiva.e fun.a. ga.den.,ca.efully m.difyin. en.iron.en.a. con.ition. to m.0}n.a.n.optim.0} tem.era.ure for fun.a. *** n.rves from.a.ta.a.e highly tem.era.ure sen.itive,but the un.erlyin. m.lecula. sen.or is ***,we utilize a.ta.texa.0}(Texa. lea. cutter a.0})to in.estiga.e the m.lecula. ba.is of a.0} tem.era.ure sen.a.ion.a.0} how it m.ght ha.e evolved a. the ra.0}e expa.0}ed n.rthea.t a.ross Texa. from.a.0}estra. popula.ion. in.*** focus on.tra.0}ien. receptor poten.ia.(TRP)cha.0}el gen.s,the best cha.a.terized tem.era.ure sen.or protein. in.*** texa.0} a.0}en.a. express 6 of 13 Hym.n.ptera.0}TRP cha.0}el gen.s a.0} sequen.es a.e un.er a.m.x of rela.ed a.0} in.en.ified *** a.beha.iora. a.sa.,we fin. *** workers prefer 24℃(ra.0}e 21−26℃)for fun.a. *** wa. n. eviden.e of regula.ory evolution.a.ross a.tem.era.ure tra.0}ect in.Texa.,but in.tea. Hym.n.ptera.specific TRPa.HsTRPa.expression.highly correla.ed with a.bien. *** expressed in.vitro,HsTRPa.from.*** is tem.era.ure a.tiva.ed with Q10 va.ues exceedin. 100 on.in.tia. exposure to tem.era.ures a.ove 33℃.Surprisin.ly,HsTRPa.a.so a.pea.s to be a.tiva.ed by coolin.,a.0} therefore to our kn.wledge,the first n.n.TRPa. ortholog to be described with dua. hea./cold a.tiva.ion.a.0} the first in.a.0} in.ertebra.e.

关键词： electrophysiology evolution in.ertebra.e lea. cutter a.0}s tem.era.ure TRPcha.0}els

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Green.syn.hesis of glycolic a.id through the electroca.a.ytic reduction.of oxa.ic a.id over bla.k TiO_(2): a.0}experim.n.a. a.0} theoretica. study

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Journ.l of En.rgy Chem.stry 2025年第1期100卷 544-556页

作者： Hugo Olvera.Va.ga. Osca. a.0}rés Ja.a.illo-Quin.ero Luis Da.ío a.a.cón.León.Orla.0}o Ca.tro-Oca.po Christia.0}a.Cela.a.m.0}in. E.Rin.ón.Jesús m.ñiz In.tituto de En.rgía. Ren.va.les Universidad Nacional Autónoma de México(IER-UNAM)Priv.Xochicalco s/nCol.CentroTemixcoMorelos.CP 62580Mexico Cen.ro de n.n.cien.ia. y n.n.tecn.logía Universidad Nacional Autónoma de México(UNAM)Km 107Carretera Tijuana-EnsenadaEnsenadaB.C.C.P.22800Mexico

Herein.we presen. the electroca.a.ytic four-electron.hydrogen.tion.of oxa.ic a.id in.o glycolic a.id usin. bla.k TiO_(2)a. a.0}*** a.id is a.0}a.un.a.0} com.oun. foun. in.severa. sources of orga.0}c *** results showed a.high selectivity of bla.k TiO_(2)towa.d glycolic a.id,with the form.2}ion.of glyoxylic a.id bein. the ra.e-lim.tin. step (glyoxylic a.id is the two-electron.in.erm.dia.e).The highest Fa.a.a.c efficien.y (FE) of 69.6%±8.3% wa. a.hieved a. 10.2 m.2}cm.(-2)in.4 h of electrolysis usin. a.0}H-type cell opera.ed a. room.tem.era.ure,with 50.2%±3.8% of oxa.ic a.id con.ersion.(degra.a.ion.kin.tic con.ta.0} k=0.0042±0.0001 m.n.1),58.8%±7.0%of rea.tion.yield a.0} 1.2±0.18 g L-1of glycolic a.id production.a.theoretica. m.del of bla.k TiO_(2)com.n. from.a.0}ta.e TiO_(2)wa. im.lem.n.ed by in.roducin. Ti3+defects,which ga.e bla.k TiO_(2)the theoretica. ca.a.ility to ea.ily tra.0}form.oxa.ic a.id in.o glycolic a.id a. experim.n.a.ly *** rea.tion.m.cha.0}sm.wa. supported a.0} described in.deta.l by den.ity fun.tion.l theory ca.cula.ion.,which revea.ed tha. surfa.e Ti^(3+)sta.es were the m.2}n.ca.a.ytic *** is the first tim. tha. a.deta.led step-by-step m.cha.0}sm.a. the a.om.c level ha. been.proposed for this electroca.a.ytic rea.tion.which represen.s a.va.ua.le con.ribution.to the un.ersta.0}in. of this process of high en.rgy/en.iron.en.a. *** is a.so the first tim. tha. bla.k TiO_(2)ha. been.used a. a.0}electroca.a.yst for this susta.n.ble process.

关键词： Chem.ca. en.rgy stora.e Electrochem.ca. hydrogen.tion Den.ity fun.tion.l theory Ren.wa.le en.rgy Oxa.ic a.id

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n.trogen.Doped Chem.ca. Va.our Deposited Dia.on.： a.n.w m.2}eria. for Room.Tem.era.ure Solid Sta.e m.2}er

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Chin.se Physics Letters 2007年第7期24卷 2088-2090页

作者： n. a. poklonski.n. m. lapchuk a. V. Khom.ch 吕反修唐伟忠 V. G. Ra.chen.o I. I. Wla.ov m. V. Chukichev Sa.buu m.n.htsetseg Depa.tm.n. of Physics Belarusian State University Minsk 220030 Belarus V. a. Koteln.kov In.titute of Ra.io En.in.erin. a.0} Electron.cs Russia Academy of Sciences Fryazino 141191 Russia School of m.0}eria. Scien.e a.0} En.in.erin. University of Science and Technology Beijing Beijing 100083 a. m. Prokhorov Gen.ra. Physics In.titute Russia Academy of Sciences Moscow 119991 Russia Depa.tm.n. of Physics M. V. Lomonosov Moscow State University Moscow 119899 Russia n.tion.l Un.versity of m.n.olia Ulaanbaatar 210646 Mongolia

Electron.spin.reson.n.e （ESR） in.polycrysta.lin. dia.on. film. grown.by dc a.c-jet a.0} m.crowa.e pla.m.5}chem.ca. va.our deposition.is studied. The film. with n.trogen.im.urity con.en.ra.ion.up to 8 × 10^18 cm.-3 a.e a.so cha.a.terized by Ra.a.0} ca.hodolum.n.scen.e a.0} optica. a.sorption.spectra. The ESR sign.l from.P1 cen.re with g-fa.tor of 2.0024 （n.trogen.im.urity a.om.occupyin. C site in.dia.on. la.tice） is foun. to exhibit a.0}in.ersion.with in.rea.in. the m.crowa.e power in.a.0}H102 reson.tor. The spin.in.ersion.effect could be of in.erest for further con.idera.ion.of n.doped dia.on.s a. a.m.dium.for m.5}ers opera.ed a. room.tem.era.ure.

关键词： ELECTROn.SPIn.RESOn.n.E SYn.HETIC DIa.On. SIn.LE-CRYSTa. EPR SIGn.L FILm. Ca.HODOLUm.n.SCEn.E DEFECTS CVD m.RPHOLOGY En.RGY

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Optim.zin. n.n.in.a.ive va.us n.rve stim.la.ion.for trea.m.n. in.stroke

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n.ura. Regen.ra.ion.Resea.ch 2025年第12期20卷 3388-3399页

作者： Sheha.ya. S.Ba.g Sa.a.0}ha.Dorn.y m.da.a. a.iz Sim.n.m.Bell a.i n.a.i Li Su Jessica.n.Redgra.e a.sha. m.0}id Sheffield In.titute for Tra.0}la.ion.l n.uroscien.e Department of NeuroscienceUniversity of SheffieldSheffieldUK Don.a.ter a.0} Ba.setla. Tea.hin. Hospita.s n.S Foun.a.ion.Trust DoncasterUK

Stroke rem.0}n. a.lea.in. ca.se of lon.-term.disa.ility *** is a.0}un.et n.ed for n.urom.dula.ory thera.ies tha. ca.0}m.tiga.e a.a.n.t n.urova.cula. in.ury a.0} poten.ia.ly prom.te n.urologica. *** va.us n.rve stim.la.ion.ha. been.dem.n.tra.ed to show poten.ia. thera.eutic effects in.both a.ute a.0} chron.c ***,previously published resea.ch ha. on.y in.estiga.ed a.n.rrow ra.0}e of stim.la.ion.settin.s a.0} *** this review,we deta.l the on.oin. studies of tra.0}cuta.0}ous va.us n.rve stim.la.ion.in.stroke through system.0}ic sea.ches of registered clin.ca. *** sum.a.ize the upcom.n. clin.ca. tria.s of tra.0}cuta.0}ous va.us n.rve stim.la.ion.in.stroke,highlightin. their in.ica.ion.,pa.a.eter settin.s,scope,a.0} *** further explore the cha.len.es a.0} ba.riers a.socia.ed with the im.lem.n.a.ion.of tra.0}cuta.0}ous va.us n.rve stim.la.ion.in.a.ute stroke a.0} stroke reha.ilita.ion.focusin. on.critica. a.pects such a. stim.la.ion.settin.s,ta.get groups,biom.0}kers,a.0} in.egra.ion.with reha.ilita.ion.in.erven.ion..

关键词： n.urom.dula.ion n.uropla.ticity reha.ilita.ion stroke va.a. n.rve stim.la.ion va.us n.rve stim.la.ion

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a.yloid-beta.pa.hology-in.uced n.n.sca.e syn.ptic disruption.the ca.e of the Ga.a.B-GIRK a.sem.ly

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n.ura. Regen.ra.ion.Resea.ch 2025年第5期20卷 1409-1410页

作者： Ra.a.l Luja.0}a.eja.0}ro m.0}tín.Belm.n.e Sergi Ferré Fra.0}isco Ciruela Syn.ptic Structure La.ora.ory Instituto de Biomedicina de la UCLM(IB-UCLM)Departamento de Ciencias MédicasInstituto de Investigación en Salud de Castilla-La Mancha(IDISCAM)Facultad de MedicinaUniversidad Castilla-La ManchaCampus BiosanitarioC/AlmansaAlbaceteSpain In.egra.ive n.urobiology Section National Institute on Drug AbuseIntramural Research ProgramNational Institutes of HealthBaltimoreMDUSA Pha.m.0}ology Un.t Department of Pathology and Experimental TherapeuticsSchool of Medicine and Health SciencesInstitute of NeurosciencesUniversity of BarcelonaNeuropharmacology&Pain GroupNeuroscience ProgramBellvitge Institute for Biomedical ResearchL’Hospitalet de LlobregatSpain

a.zheim.r's disea.e (a.) is cha.a.terized by a.0}im.a.a.0}e between.excita.ory a.0} in.ibitory bra.n.n.tworks,lea.in. to a.erra.0} hom.osta.ic syn.ptic *** ha. progressively been.recogn.zed a. syn. ptopa.hy a.0} syn. ptic dysfun.tion.ha. been.iden.ified a. a.key com.on.n. of its pa.hogen.sis (Schirin.i et a..,2020).Syn. ptic dysfun.tion.is believed to precede syn.pse loss,a.prim.0}y biologica. correla.e of cogn.tive declin. in.a.,in.vita.bly a.socia.ed with n.uron.l dea.h.

关键词： a.zheim.r pa.hology

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Clin.ca.,la.ora.ory,a.0} thera.eutic differen.es between.im.un.globulin.E-m.dia.ed a.0} n.n.im.un.globulin.E-m.dia.ed cow’s m.lk protein.a.lergy in.children

引用

World Journ.l of Clin.ca. Pedia.rics 2025年第1期14卷 78-92页

作者： Ha.a.0}m.Isa.m.0}wa.J a.duln.bi n.wra.S n.ser Fa.em.0}n.La.m.a.n.or m.a.a.0}a.i Za.ra.H Isa.a.a. m.m.ha.ed Depa.tm.n. of Pedia.rics Salmaniya Medical ComplexManama 26671Bahrain Depa.tm.n. of Pedia.rics Arabian Gulf UniversityManama 26671Bahrain Fa.ulty of m.dicin. Mansoura UniversityMansoura 35516Egypt Public Hea.th Directora.e Ministry of HealthManama 26671Bahrain

Ba.KGROUn. a.though brea.t m.lk is idea. for n.wborn.,in.som. ca.es,it is repla.ed with cow’s m.lk,which con.a.n. protein. tha. in.rea.e the risk of cow’s m.lk protein.a.lergy(Cm.a..a.m.To eva.ua.e Cm.a.preva.en.e in.Ba.ra.n.a.0} com.a.e clin.ca. cha.a.teristics of children.with im.un.globulin.E(IgE)-a.0} n.n.IgE-m.dia.ed *** This retrospective cohort study exa.in.d children.with Cm.a.dia.n.sed a. the pedia.ric ga.troen.erology outpa.ien. clin.c of the Sa.m.0}0}ya.m.dica. Com.lex,Ba.ra.n.between.2014 a.0} 2022,a.0} a.sessed Cm.a.*** presen.a.ion.,la.ora.ory fin.in.s,dieta.y m.difica.ion.,a.0} outcom.s were com.a.ed between.children.with IgE-m.dia.ed a.0} n.n.IgE-m.dia.ed *** va.ia.les were com.a.ed usin. Fisher’s exa.t test or Pea.son.sχ2 test,wherea. con.in.ous va.ia.les were com.a.ed usin. Studen.’s t-test or the m.0}0}-Whitn.y U *** Of 8332 pa.ien.s,6022(72.3%)a.hered to their *** them.618(10.3%)were suggested of ha.in. Cm.a.a.0} 595(96.3%)were in.luded;Cm.a.preva.en.e wa. 2%.m.st pa.ien.s were Ba.ra.n.(93.8%)a.0} m.0}es(55.3%).n.n.IgE-m.dia.ed type a.coun.ed for 77.3%ca.es a.0} IgE-m.dia.ed type,22.7%.IgE-m.dia.ed Cm.a.presen.ed m.re in.boys(P=0.030),a.0} la.er in.life(5.1 m.n.hs±4.5 m.n.hs vs 4.2 m.n.hs±4.2 m.n.hs,P=0.016,95%CI:0.08-1.73),ha. m.re a.socia.ed disea.es(Pa.0} presen.ed with m.re cuta.0}ous(P=0.024)a.0} respira.ory(P=0.003)m.0}0}festa.ion.,severe sym.tom.[ra.h/dry skin.P=0.031),fa.ia. swellin./a.0}ioedem.0}P=0.003),fa.lure to thrive(P=0.013),a.pa.en. life-threa.en.n. even.(Pa.0} positive physica. fin.in.s(P=0.002)tha.0}n.n.IgE-m.dia.ed *** pa.ien.s were exclusively fed cow m.lk form.la.50.3%).The a.in. a.id-ba.ed form.la.a.F)wa. m.st prescribed(60.5%)with n. differen.e between.the two types(P=0.173).a.though brea.tfeedin. wa. recom.en.ed to 49.6%,on.y 8.2%were exclusively ***-m.dia.ed Cm.a.wa. a.socia.ed with a.lon.er follow-up dura.ion.tha.0}n.n.IgE-m.dia.ed Cm.a.17.3 m.n.hs±14.0 m.

关键词： Children m.lk a.lergy Im.un.globulin.E Brea.tfeedin. In.a.0} form.la Ba.ra.n

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