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THE ACTIOn OF RADIX REHMAnnIAE AnD PLASTRUM TESTUDInIS On BETA- ADREnERGIC RECEPTOR-cAMP SySTEM

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中华医学杂志(英文版) 1987年第11期100卷 898-898页

作者： n y yi G P Feng y M yu y Z Lin Z X Rong Z Q Xia S D Zhang y E Hu Department of Pharmacology Shanghai Second Medical University Isotope Laboratory Shanghai Second Medical University Shanghai

Mouse and rat pathological models were produced by injections of thyroid hormone (T3 or T4, Model I) or hydrocortisone (HC, Model II). A single subcutaneous dose of isoproterenol (ISO) caused plasma cAMP to peak in 5-15 min which was significantly higher in mouse Models I and II than in normal mice. Daily oral administration of a decoction of two yin tonics-Radix Rehmanniae (RR) and Plastrum Testudinis (PT) reduced peak cAMP in both models.3H-DHA binding assay re vealed significant elevations of the number of β-adrenergic receptors in rat Models I and II. Decoction RR and PT restored the peaks to normal range. yang tonics Radix Aconiti praeparata (RAP) and Cortex Cinnamomi (CC) showcd contradictory effects on these models. It seems unlikely that the action of the two tonics promotes the clearance of injected hormones, since injected hormone RIA in plasma showed no differences between yin tonics treated and untreated models. The therapeutic effects of these two yin tonics on "yin deficiency" syndrome of hyperthyroidism or hyperfunction of the adrenal cortex is very probably related to their actions on the β-adrenoreceptor-cAMP system as stated.

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Different effects of economic and structural performance indexes on model construction of structural topology optimization

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Acta Mechanica Sinica 2015年第5期31卷 777-788页

作者： G.L.yi y.K.Sui College of Mechanical Engineering and Applied Electronics Technology Beijing University of Technology Department of Mechanical and Aerospace Engineering Seoul National University

The objective and constraint functions related to structural optimization designs are classified into economic and performance indexes in this *** influences of their different roles in model construction of structural topology optimization are also ***,two structural topology optimization models,optimizing a performance index under the limitation of an economic index,represented by the minimum compliance with a volume constraint（MCVC）model,and optimizing an economic index under the limitation of a performance index,represented by the minimum weight with a displacement constraint（MWDC）model,are *** on a comparison of numerical example results,the conclusions can be summarized as follows：（1）under the same external loading and displacement performance conditions,the results of the MWDC model are almost equal to those of the MCVC model;（2）the MWDC model overcomes the difficulties and shortcomings of the MCVC model;this makes the MWDC model more feasible in model construction;（3）constructing a model of minimizing an economic index under the limitations of performance indexes is better at meeting the needs of practical engineering problems and completely satisfies safety and economic requirements in mechanical engineering,which have remained unchanged since the early days of mechanical engineering.

关键词： Economic index Performance index Structural topology optimization models MCVC model MWDC model Safety and economy

A comparative study on polypropylene separators coated with different inorganic materials for lithium-ion batteries

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Frontiers of Chemical Science and Engineering 2017年第3期11卷 346-352页

作者： Linghui yu Jiansong Miao yi Jin Jerry y.S. Lin School for Engineering of Matter Transport and Energy Arizona State University Tempe AZ 85287 USA State Key Laboratory of Operation and Control of Renewable Energy & Storage Systems China Electric Power Research Institute Beijing 100192 China

Coating commercial porous polyolefin separators with inorganic materials can improve the thermal stability of the polyolefin separators and hence improve the safety of lithium-ion batteries. Several different inorganic materials have been studied for the coating. However, there lacks a study on how different the properties of separators, in inorganic materials affect terms of thermal stability and cell performance. Herein, we present such a study on coating a commercial polypropylene separator with four inorganic materials, i.e., Al2O3, SiO2, ZrO2 and zeolite. All inorganic coatings have improved thermal stability of the separators although with differences. The coating layers add 28%-45% of electrical resistance compared with the pure polypropylene separator, but all the cells prepared with the coated polypropylene separators have the same electrical chemical performance as the uncoated separator in terms of rate capability and capacities at different temperatures.

关键词： lithium-ion battery battery safety composite separator porosity tortuosity

Symmetries of boundary layer equations of power-law fluids of second grade

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Acta Mechanica Sinica 2008年第6期24卷 661-670页

作者： Mehmet Pakdemirli yi■it Aksoy Muhammet yürüsoy Chaudry Masood Khalique Department of Mechanical Engineering Celal Bayar University45140 MuradiyeManisaTurkey Technical Education Faculty Afyon Kocatepe UniversityAfyonTurkey Department of Mathematical Sciences International Institute for Symmetry Analysis and Mathematical ModelingNorth-West UniversityMafikeng CampusPrivate Bag X 2046Mmabatho 2735South Afiica

A modified power-law fluid of second grade is considered. The model is a combination of power-law and second grade fluid in which the fluid may exhibit normal stresses, shear thinning or shear thickening behaviors. The equations of motion are derived for two dimensional incompressible flows, and from which the boundary layer equations are derived. Symmetries of the boundary layer equations are found by using Lie group theory, and then group classification with respect to power-law index is performed. By using one of the symmetries, namely the scaling symmetry, the partial differential system is transformed into an ordinary differential system, which is numerically integrated under the classical boundary layer conditions. Effects of power-law index and second grade coefficient on the boundary layers are shown and solutions are contrasted with the usual second grade fluid solutions.

关键词： Power-law fluid of second grade Boundarylayers Lie group theory

Langmuir-Schaefer Film Investigation and Density Functional Theory Band Gap Calculations of Calix[n]arene-Para-Aminobenzoic Acid for Drug nanosensor Application

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Journal of Wuhan University of Technology(Materials Science) 2024年第5期39卷 1311-1318页

作者： WOnG yeong yi F L Supian A Radzwan M Musa n F n Abd Karim Department of Physics Sultan Idris Education UniversityTanjong Malim 35900Malaysia Department of Chemistry Sultan Idris Education UniversityTanjong Malim 35900Malaysia

Calix[n]arenes was utilized to detect PABA,the primary sunscreen *** study investigates the interaction of calix[4]arene(C4),calix[6]arene(C6),and PABA using the Langmuir method and first-principle density functional theory(DFT).Using the Langmuir-Schaefer(LS)technique,an ultrathin film composed of calix[n]arenes and their complexes with PABA was deposited on various *** on the Langmuir study,the PABA molecule was bonded to the lower rims of both C4 and C6 with the host-guest ratio of 1:*** of the LS films formed were then characterized by ultravioletvisible spectroscopy(UV-Vis),Fourier-transform infrared spectroscopy(FTIR)and carbon,hydrogen,nitrogen,sulfur elemental analyzer(CHnS).The band gap reduction obtained in the DFT study denotes the charge transfer interaction with promising reactivity between the calix[n]arenes and *** sensing of PABA by C4 and C6 is successful based on the formation of bonding between them due to the hosts’effective trapping *** outcomes of this study could be applied to drug delivery systems for future pharmaceutical and medical applications.

关键词： calix[n]arenes band gap density functional theory Langmuir-Schaefer PABA sensor

A nEW CHROME GLyCOSIDE FROM SMILAX GLABRA ROXB

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Chinese Chemical Letters 1995年第7期6卷 587-588页

作者： Cao, ZZ yi, yJ Cao, y Leng, ZK nanjing Inst Mat Med Nanjing 210009 Peoples R China

A new chrome glycoside, 5,7-dihydroxychromone-3-O-L-rhamnopyranoside, named smiglanin, was isolated from the root of Smilax glabra collected in Lanxi, Zhejiang province. Its structure was elucidated by special data an...

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Mesoporous carbon nanomaterials induced pulmonary surfactant inhibition,cytotoxicity,inflammation and lung fibrosis

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Journal of Environmental Sciences 2017年第12期29卷 100-114页

作者： yunan Chen yi yang Bolong Xu Shunhao Wang Bin Li Juan Ma Jie Gao yi y.Zuo Sijin Liu State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China Department of Mechanical Engineering University of Hawaii at ManoaHonoluluHI 96822USA Beijing Key Laboratory of Bioprocess Beijing Advanced Innovation Center for Soft Matter Science Engineering Beijing Laboratory of Biomedical MaterialsBeijing University of Chemical TechnologyBeijing 100029China

Environmental exposure and health risk upon engineered nanomaterials are increasingly concerned. The family of mesoporous carbon nanomaterials（MCns） is a rising star in nanotechnology for multidisciplinary research with versatile applications in electronics,energy and gas storage, and biomedicine. Meanwhile, there is mounting concern on their environmental health risks due to the growing production and usage of MCns. The lung is the primary site for particle invasion under environmental exposure to nanomaterials. Here, we studied the comprehensive toxicological profile of MCns in the lung under the scenario of moderate environmental exposure. It was found that at a low concentration of 10 μg/mL MCns induced biophysical inhibition of natural pulmonary surfactant. Moreover, MCns at similar concentrations reduced viability of J774 A.1 macrophages and lung epithelial A549 *** with nature pulmonary surfactant effectively reduced the cytotoxicity of *** the pro-inflammatory responses, MCns activated macrophages in vitro, and stimulated lung inflammation in mice after inhalation exposure, associated with lung ***, we found that the size of MCns played a significant role in regulating cytotoxicity and pro-inflammatory potential of this nanomaterial. In general, larger MCns induced more pronounced cytotoxic and pro-inflammatory effects than their smaller counterparts. Our results provided valuable information on the toxicological profile and environmental health risks of MCns, and suggested that fine-tuning the size of MCns could be a practical precautionary design strategy to increase safety and biocompatibility of this nanomaterial.

关键词： Mesoporous carbon nanomaterials Environmental exposure Pulmonary surfactant Inflammation Fibrosis

Challenges and opportunities for battery health estimation:Bridging laboratory research and real-world applications

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Journal of Energy Chemistry 2024年第2期89卷 434-436,I0011页

作者： Te Han Jinpeng Tian C.y.Chung yi-Ming Wei Center for Energy and Environmental Policy Research Beijing Institute of TechnologyBeijing 100081China School of Management and Economics Beijing Institute of TechnologyBeijing 100081China Department of Electrical and Electronic Engineering and Research Centre for Grid Modernization The Hong Kong Polytechnic UniversityKowloon 999077Hong KongChina

Addressing climate change demands a significant shift away from fossil fuels,with sectors like electricity and transportation relying heavily on renewable *** to this transition are energy storage systems,notably lithium-ion *** time,these batteries degrade,affecting their efficiency and posing safety *** and predicting battery aging is essential,especially estimating its state of health(SOH).Various SOH estimation methods exist,from traditional model-based approaches to machine learning approaches.

关键词： Energy storage systems State of health Multi-source data Scientific AI Data-sharing mechanism

Efects of Rare Earth on Austenite–Ferrite Phase Transformation in a Low‑Carbon Fe–C Alloy

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Acta Metallurgica Sinica(English Letters) 2023年第1期36卷 141-146页

作者： Fei Guo Cheng‑Wu Zheng Pei Wang Dian‑Zhong Li yi‑y Shenyang national Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China

The infuence of rare earth(RE)elements on austenite–ferrite phase transformation in Fe–0.14%C alloy has been investigated by in situ observing the nucleation,growth and morphology of ferrite using high temperature laser scanning confocal microscopy,and controlled atmosphere decarburization *** is found that under the low-oxygen condition in steel,trace RE addition can signifcantly infuence the nucleation,morphology and growth of ferrite in Fe–0.14%C alloy by the combined efects of RE slowing down the carbon difusion and decreasing grain boundary energy by segregating at grain *** research provides evidences of adjusting the phase transformation and improving the mechanical properties of steels by RE addition.

关键词： Steels Difusion Austenite-ferrite transformation Kinetics Rare earth