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Assessment of participant satisfaction with upper gastrointestinal endoscopy in South Korea

World Journal of Gastroenterology 2011年第36期17卷 4124-4129页

作者： Hoo-Yeon Lee Sun Mi Lim Mi Ah han Jae Kwan Jun Kui Son Choi myung-Il Hahm Eun-Cheol Park Department of Social Medicine College of MedicineDankook University201Manghyang-roDongnamguCheonan-siChungcheongnam-do 330-714South Korea National Cancer Control Institute National Cancer CenterGyeonggi-do 410-769South Korea Mi Ah HanDepartment of Preventive MedicineCollege of MedicineChosun UniversitySeoseok-dongDong-guGwangju 501-759South Korea Department of Preventive Medicine College of MedicineChosun UniversitySeoseok-dongDong-guGwangju 501-759South Korea National Cancer Control Institute National Cancer CenterGyeonggi-do 410-769South Korea Department of Health Administration and Management College of Medical ScienceSoonchunhyang UniversityShinchang-myunAsan-siChungcheongnam-do 336-745South Korea Department of Preventive Medicine and Institute of Health Services Research College of MedicineYonsei UniversitySeoul 120-752South Korea

AIM:To measure the perceived satisfaction with gastric cancer screening as part of the National Cancer Screening Program (NCSP) in South ***:Data were derived from the participantsin a satisfaction survey of the Quality Evaluation of National Cancer Screening in *** is a populationbased nationwide telephone survey of participants who were screened by the NCSP between May and October *** study included 4412 participants who provided full sets of data and who had upper endoscopies for the purpose of gastric cancer ***:The negative appraisal percentages for each of the seven questions were as follows:explanation in preparation for the upper endoscopy,12.3%;explanation about the process and procedure of the upper endoscopy,13.8%;explanation about any pain or discomfort related to the upper endoscopy,27.5%;level of pain during the procedure,30.3%;physical environment,16.2%;manner of the staff,11.2%,and privacy protection,8.8%.CONCLUSION:The critical issues identified by the Pareto analysis include the adequacy of the explanation about any pain or discomfort associated with the upper endoscopy and the level of pain experienced during the procedure.

关键词： Gastric cancer Cancer screening Upper endoscopy Satisfaction

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Meta-analysis on randomized controlled trials for scalp acupuncture treatment of stroke：A systematic review

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Journal of Traditional Chinese Medicine 2018年第4期38卷 465-479页

作者： Young-Nim You Min-Yeong Song Gwang-Cheon Park Chang-Su Na Jae-Young han myung-Rae Cho Jae-Hong Kim Clinical Research Center Dong-Shin University Gwangju Oriental Hospital Gwangju City 61619 Republic of Korea Department of Acupuncture and Moxibustion Medicine College of Korean Medicine Dong-Shin University Naju City 58245 Republic of Korea Department of Korean Rehabilitation Therapy College of Korean Medicine Dong-Shin University Naju City 58245 Republic of Korea Department of Meridians and Acupoints College of Korean Medicine Dong-Shin University Naju City 58245 Republic of Korea Department of Physical & Rehabilitation Therapy Chonnam National University Medical School & Hospital Gwangju City 61619 Republic of Korea

OBJECTIVE:To conduct a systematic review to assess the clinical effectiveness of scalp acupuncture(SA) for ***:Literature searches were performed in7 databases up to 16 August 2014,and all the randomized controlled trials(RCTs) in which SA therapy was administered to stroke patients were *** quality was assessed using the Jadad score,the Cochrane risk of bias assessment,and the Standards for Reporting Interventions in Clinical Trials of ***:Of a total of 2086 papers,21 RCTs were ***-analysis revealed significant differences in the total efficacy rates of the SA group and the body acupuncture(BA) group vs the medication group(P < 0.002,P < 0.000 001,respectively),the SA plus BA group vs the BA group(P < 0.001);in the motor function of the SA plus BA group vs the BA group(P = 0.077);and in the nerve function of the SA group vs the SA plus BA group(P < 0.0001).CONCLUSION:The results of our systematic review showed that SA therapy may exhibit effects in treatment efficacy and in the recovery of motor and nervous functions in patients with acute to chronic ***,because of the lack of methodological quality,the thoroughly planned clinical studies are still required.

关键词： Stroke Review ized controlled trial Scalprisk of bias Jadad scoreMeta-analysis Random-acupuncture Cochrane

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Chronic gastrointestinal symptoms and quality of life in the Korean population

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World Journal of Gastroenterology 2008年第41期14卷 6388-6394页

作者： Jeong-Jo Jeong myung-Gyu Choi Young-Seok Cho Seung-Geun Lee Jung-Hwan Oh Jae-myung Park Yu-Kyung Cho In-Seok Lee Sang-Woo Kim Sok-Won han Kyu-Yong Choi In-Sik Chung Department of Internal Medicine the Catholic University of Korea Department of Biostatistics University of North Carolina at Chapel Hill NC

AIM： To evaluate the prevalence of chronic gastroin- testinal symptoms and their impact on health-related quality of life （HRQOL） in the Korean population. METHODS： A cross-sectional survey, using a reliable and valid Rome I] based questionnaire, was per- formed on randomly selected residents, between 18 and 69 years in age. All respondents were interviewed at their homes or offices by a team of interviewers. The impact of chronic gastrointestinal symptoms on HRQOL was assessed using the Korean version of the 36-item Short-Form general health survey （SF-36）. RESULTS： Of the 1807 eligible subjects, 1417 （78.4%： male 762; female 655） were surveyed. Out of the respondents, 18.6% exhibited at least one chronic gastrointestinal symptom. The prevalence of gastro- esophageal reflux disease （GERD）, defined as heart- burn and/or acid regurgitation experienced at least weekly, was 3.5% （95% CI, 2.6-4.5）. The prevalence of uninvestigated dyspepsia, irritable bowel syndrome （IBS） and chronic constipation based on Rome Ⅱ criteria were 11.7% （95% CI, 10.1-13.5）, 2.2% （95% CI, 1.5-3.1）, and 2.6% （95% CI, 1.8-3.5） respectively. Compared with subjects without chronic gastrointesti- nal symptoms （n = 1153）, those with GERD （n = 50）, uninvestigated dyspepsia （n = 166） and IBS （n = 31） had significantly worse scores on most domains of the SF-36 scales. CONCLUSION： The prevalence of GERD, uninvesti- gated dyspepsia and IBS were 3.5%, 11.7% and 2.2% respectively, in the Korean population. The health- related quality of life was significantly impaired in subjects with GERD, uninvestigated dyspepsia and IBS in this community.

关键词： Chronic gastrointestinal symptom Gastroesophageal reflux disease Dyspepsia Irritable bowel syndrome Qaulibl of life

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Profile of Yi-han Chen

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Science China(Life Sciences) 2017年第4期60卷 345-347页

作者： Chen Yi-han

***-han Chen is an excellent cardiologist and a medical *** more than two decades of clinical and biomedical research work,he has made remarkable achievements in regards to treatment and pathogenesis of cardiac arrhythmias and heart failure,and was elected as a member of the Chinese Academy of Sciences in 2015 because of his outstanding contributions.

关键词： contributions pathogenesis outstanding affiliated biomedical remarkable behalf editorial department focusing

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高硫铝土矿焙烧脱硫及精矿溶出性能研究

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有色金属（冶炼部分） 2025年第1期 59-65页

作者：武国宝韩东战中铝郑州有色金属研究院有限公司郑州450041

对某矿区高硫铝土矿进行了不同焙烧方式的脱硫试验,提出了一种模拟流态化焙烧脱硫过程的静态焙烧试验方法,进行了系统的焙烧脱硫试验,确定了较适宜的焙烧脱硫工艺条件,考察了焙烧过程对精矿溶出性能的影响。在磨矿粒度250μm筛下含量≥9... 详细信息

对某矿区高硫铝土矿进行了不同焙烧方式的脱硫试验,提出了一种模拟流态化焙烧脱硫过程的静态焙烧试验方法,进行了系统的焙烧脱硫试验,确定了较适宜的焙烧脱硫工艺条件,考察了焙烧过程对精矿溶出性能的影响。在磨矿粒度250μm筛下含量≥90.84%、焙烧温度580~600℃、焙烧时间2 min的条件下,精矿中全硫(ST)含量可降低至0.50%左右,S2−含量不超过0.10%;在石灰添加量10%、溶出温度265℃、溶出液αk=1.35~1.39及溶出时间50 min的条件下,精矿的氧化铝溶出率>89%,溶出赤泥A/S=1.31~1.34,N/S=0.15~0.16。在相同溶出试验条件下,与原矿相比,焙烧精矿溶出性能变化不大。

关键词：高硫铝土矿焙烧脱硫溶出

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Rapid manufacturing of SiC molds with micro-sized holes using abrasive water jet

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中国有色金属学会会刊：英文版 2009年第B9期19卷 178-182页

作者： Bo-Sung SHIN Kang-Su PARK Yeon-Kyoung BAHK Sun-Ki PARK Jung-han LEE Jeung-Sang GO myung-Chang KANG Chae-Moon LEE ERC/NSDM Pusan National University School of Mechanical Engineering Pusan National University Microhole Company NCRC Pusan National University Samsung Electro-Mechanics

Silicon carbide (SiC) is highly wear resistant with good mechanical properties, including high temperature strength, excellent chemical resistance, and high thermal conductivity and thermal shock resistance. SiC molds, which can be produced with diverse microstructural features, are now widely used in glass molding owing to their excellent characteristics, and also have potential applicability in IT industries. SiC molds are traditionally fabricated by silicon micromachining or dicing. The fabrication cost of silicon micromachining is very high, however, because several expensive masks are needed. Furthermore, the fabrication time is very long. Meanwhile, it is difficult to make micro-patterned molds with arbitrary shapes using dicing saws. Abrasive water jet (AWJ) is widely applied to cut and drill very brittle, soft and fibrous materials. It offers high energy density, the absence of a heat affected zone(HAZ), high performance, and an environment friendly process. In spite of these advantages, micro-hole drilling via conventional AWJ processing suffers from notable shortcomings. We proposed a new abrasive supplying method of AWJ. The proposed method reduces frosting phenomena, and provides micro-machining of AWJ. The characteristics of a hole machined was investigated by the proposed AWJ process according to the ratio of water and abrasives. With the optimal experimental conditions, 3×3 array SiC molds with the diameter of 700 μm and depth of 900 μm were successfully manufactured.

关键词：快速模具制造磨料水射流碳化硅微型硅微加工型孔最佳实验条件机械性能

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Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury

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Neural Regeneration Research 2025年第5期20卷 1467-1482页

作者： Wenrui Qu Xiangbing Wu Wei Wu Ying Wang Yan Sun Lingxiao Deng Melissa Walker Chen Chen Heqiao Dai Qi han Ying Ding Yongzhi Xia George Smith Rui Li Nai-Kui Liu Xiao-Ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA Department of hand Surgery the Second Hospital of Jilin UniversityChangchunJilin ProvinceChina Shriners Hospitals Pediatric Research Center Temple University School of MedicinePhiladelphiaPAUSA Department of Anatomy&Cell Biology Indiana University School of MedicineIndianapolisINUSA

Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal *** we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord *** report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal *** Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder ***,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord *** findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.

关键词： axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation

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ALOXE3基因突变致常染色体隐性先天性鱼鳞病一例

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中国麻风皮肤病杂志 2025年第1期41卷 9-14页

作者：韩春雨韩建文内蒙古医科大学附属医院内蒙古呼和浩特010000

目的:明确一例常染色体隐性鱼鳞病基因突变及0.5%神经酰胺乳膏治疗效果。方法:收集先证者的临床资料,提取先证者及其亲属外周血DNA,采用序列捕获技术对相关基因进行高通量测序,并对其变异位点进行一代验证。明确诊断后给予先证者外用0.5... 详细信息

目的:明确一例常染色体隐性鱼鳞病基因突变及0.5%神经酰胺乳膏治疗效果。方法:收集先证者的临床资料,提取先证者及其亲属外周血DNA,采用序列捕获技术对相关基因进行高通量测序,并对其变异位点进行一代验证。明确诊断后给予先证者外用0.5%神经酰胺乳膏治疗,并随访10个月。结果:先证者皮损组织病理符合鱼鳞病病理改变,全基因组外显子测序及Sanger测序验证发现先证者ALOXE3基因存在复合杂合突变(错义变异c.1208A>G:p.H403R和一个移码变异c.102dup:p.K35Qfs^(*)29)。先证者的母亲(错义变异c.1208A>G:p.H403R)和父亲(移码变异c.102dup:p.K35Qfs^(*)29)分别是单个突变的携带者。给予外用0.5%神经酰胺乳膏治疗10个月,全身皮肤干燥及褐色鳞屑得到明显改善。结论:ALOXE3基因的复合杂合突变可能是该常染色体隐性鱼鳞病患者的病因。0.5%神经酰胺乳膏治疗可取得良好效果。

关键词：常染色体隐性先天性鱼鳞病 ALOXE3基因复合杂合突变神经酰胺乳膏

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Use of NiO/SiO_2 catalysts for toluene total oxidation:Catalytic reaction at lower temperatures and repeated regeneration

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Chinese Journal of Catalysis 2016年第11期37卷 1931-1940页

作者： Sang Wook han myung-Geun Jeong Il Hee Kim Hyun Ook Seo Young Dok Kim 韩国成均馆大学化学系韩国化学技术研究所(KRICT)纳米催化剂研究中心

We deposited NiO via atomic layer deposition on mesoporous SiO2 particles with diameters of several hundred micrometers and a mean mesopore size of -14 *** was deposited within the shell region of mesoporous SiO2 particles with a shell thickness of -11 *** annealed the as-prepared NiO/SiO2 at 450 and 600℃,*** two samples were used as catalysts for the uptake of toluene molecules and their oxidative conversion to *** sample annealed at450℃ was generally more reactive in toluene uptake and its subsequent conversion to *** the NiO/SiO2 annealed at 450℃ was exposed to toluene vapor at 160℃ and then heated to 450℃,CO2 was emitted with almost no toluene *** suggest that our catalysts can be used as building blocks for odor removal devices that operate below 200℃.These catalysts can be regularly regenerated at -450℃.

关键词： Heterogeneous catalysis Chemisorption Thermal desorption Mesoporous material Toluene oxidation

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Northern Chinese han populations with sporadic Alzheimer’s disease and the role of urokinase-type plasminogen activator gene promoter polymorphisms

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Neural Regeneration Research 2010年第2期5卷 150-155页

作者： Di han Yan Wang Hongyun Li Jianping Jia Department of Emergency Neurology Medical School Hospital of Qingdao University Qingdao 266003 Shandong Province China Department of Neurology Medical School Hospital of Qingdao University Qingdao 266003 Shandong Province China Department of Neurology Xuanwu Hospital of the Capital Medical University Beijing 100053 China

BACKGROUND; Polymorphisms of urokinase-type plasminogen activator gene （PLAU） have recently been reported to be associated with sporadic Alzheimer＇ disease （SAD）. However, most studies have focused on the exon region of this gene, and there is no report on the association between promoter polymorphisms of the PLAU and SAD. OBJECTIVE： To determine whether SAD is associated with promoter polymorphisms of PLAU in Northem han Chinese. DESIGN, TIME AND SETTING： A case-control study was performed at Neurology Laboratory of Xuanwu Hospital of the Capital Medical University from September 2006 to July 2008. PARTICIPANTS： A total of 397 participants living in Beijing were assigned to SAD [n = 196, including 103 males and 93 females, mean age of （64 ± 7） years] and control [n = 201, including 108 males and 93 females, mean age of （68 ± 6） years] groups. The patients were diagnosed and met the National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer＇s Disease and Related Disorder Association criteria for possible Alzheimer＇s disease. Controls received clinical, mental, and neurological examinations to rule out cognitive deficiencies. All controls had Mini-Mental Status Examination scores 〉 27. METHODS： Genotypes of PLAU and apolipoprotein-E were examined in 196 patients with SAD and 201 age- and sex-matched controls from the same community using polymerase chain reaction-restriction fragment length polymorphism method. SPSS 11.5 software was used for data analysis, distribution of allele and genotypic frequency were calculated, and Hardy-Weinberg was also performed in this study. MAIN OUTCOME MEASURES： The main outcome measures were allele and genotype frequency differences in the promoter region of the PLAU gene between SAD and control subjects. RESULTS： In Chinese han populations, the two polymorphisms in PLAU promoter were -25 C/T （rs2227579） and 43 G/T （rs2227580）. Detection of these promoter polymorphisms revealed significant differences in alle

关键词： PLAU gene promoter Alzheimer's disease polymorphism

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