检索结果-南通市图书馆

Porously Reduced 2-Dimensional Bi_(2)O_(2)CO_(3) Petals for Strain-Mediated Electrochemical CO_(2) Reduction to HCOOH

在线全文

学校读者我要写书评

暂无评论

Energy & Environmental Materials 2024年第1期7卷 215-221页

作者： Won seok Cho Dae myung Hong Wan Jae Dong Tae Hyung lee Chul Jong Yoo Donghwa lee Ho Won Jang Jong-Lam lee Department of Materials Science and Engineering Pohang University of Science and Technology(POSTECH)Pohang Gyungbuk 37673Korea Department of Materials Science and Engineering Research Institute of Advanced Materials Seoul National UniversitySeoul 08826Korea

Here we introduce bismuth-based catalysts for the efficient electrochemical reduction of CO_(2)to formic acid(HCOOH),which are composed of petal-shaped Bi_(2)O_(2)CO_(3)(BOC)that spontaneously formed from Bi thin film in aqueous carbonate solution at room *** the electrochemical reduction process,the BOC petals transform to reduced BOC(R-BOC)consisting of individual BOC and Bi *** mismatch between both domains induces biaxial strain at the *** functional theory calculations suggest that the tensile strain on the Bi domain stabilizes the*OCHO intermediate,reducing the thermodynamic barrier toward CO_(2)conversion to *** with the thermodynamic benefit and the unique nanoporous petal-shaped morphology,R-BOC petals have a superior Faradaic efficiency of 95.9%at-0.8 V_(RHE)for the electrochemical conversion of CO_(2)to *** work demonstrates that the spontaneously formed binary phases with desirable lattice strain can increase the activity of bismuth catalysts to the CO_(2)reduction reaction;such a strategy can be applicable in design of various electrocatalysts.

关键词： bismuth carbon dioxide reduction formic acid heterointerfaces strain

Evidence from a familial case suggests maternal inheritance of primary biliary cholangitis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第39期23卷 7191-7197页

作者： Saeam Shin In Ho Moh Young Sik Woo Sung Won Jung Jin Bae Kim Ji Won Park Ki Tae Suk Hyoung Su Kim Mineui Hong Sang Hoon Park myung seok lee Department of Laboratory Medicine Kangnam Sacred Heart Hospital Hallym University College of Medicine Division of Gastroenterology and Hepatology Department of Internal Medicine Kangnam Sacred Heart Hospital Hallym University College of Medicine Department of Pathology Kangnam Sacred Heart Hospital Hallym University College of Medicine

Primary biliary cholangitis(PBC) is an idiopathic autoimmune liver disease characterized by chronic cholestasis and destruction of the intrahepatic bile ducts. Similar to other autoimmune diseases, the pathogenesis of PBC is considered to be a complex etiologic phenomenon involving the interaction of genetic and environmental factors. Although a number of common variants associated with PBC have been reported from genome-wide association studies, a precise genetic mechanism underlying PBC has yet to be identified. Here, we describe a family with four sisters who were diagnosed with PBC. After the diagnosis of the index patient who was in an advanced stage of PBC, one sister presented with acute hepatitis, and two sisters were subsequently diagnosed with PBC. Notably, one half-sister with a different mother exhibited no evidence of PBC following clinical investigation. Our report suggests the possibility of a maternal inheritance of PBC susceptibility. Moreover, judging from the highpenetrance of the disease observed in this family, we inferred that a pathogenic genetic variant might be the cause of PBC development. We describe a family that exhibited diverse clinical presentations of PBC that included asymptomatic stages with mildly increased liver enzyme levels and symptomatic stages with acute hepatitis or advanced liver fibrosis. Additional studies are needed to investigate the role of genetic factors in the pathogenesis of this rare autoimmune disease.

关键词： Primary biliary cholangitis Family history Genetic susceptibility

Nanoparticle Exsolution on Perovskite Oxides:Insights into Mechanism,Characteristics and Novel Strategies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第2期16卷 312-346页

作者： Yo Han Kim Hyeongwon Jeong Bo‑Ram Won Hyejin Jeon Chan‑ho Park Dayoung Park Yeeun Kim Somi lee Jae‑ha myung Department of Materials Science and Engineering Incheon National UniversityIncheon 22012Republic of Korea

Supported nanoparticles have attracted considerable attention as a promising catalyst for achieving unique properties in numerous applications,including fuel cells,chemical conversion,and *** demonstrate high activity by expanding the number of active sites,but they also intensify deactivation issues,such as agglomeration and poisoning,*** for bottomup synthesis of supported nanoparticles has emerged as a breakthrough technique to overcome limitations associated with conventional *** are uniformly exsolved from perovskite oxide supports and socketed into the oxide support by a one-step reduction *** uniformity and stability,resulting from the socketed structure,play a crucial role in the development of novel ***,tremendous research efforts have been dedicated to further controlling exsolution *** effectively address exsolution at a more precise level,understanding the underlying mechanism is *** review presents a comprehensive overview of the exsolution mechanism,with a focus on its driving force,processes,properties,and synergetic strategies,as well as new pathways for optimizing nanocatalysts in diverse applications.

关键词： Supported nanoparticle Exsolution In situ growth Mechanism Perovskite oxide Catalyst

Differentiation of acute and chronic hepatitis B in IgM antiHBc positive patients

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第13期21卷 3953-3959页

作者： Ji Won Park Kyeong Min Kwak Sung Eun Kim Myoung Kuk Jang Dong Joon Kim myung seok lee Hyoung Su Kim Choong Kee Park Department of Internal Medicine Hallym University Medical CenterAnyang 431-070South Korea Department of Occupational and Environmental Medicine Hallym University Medical CenterAnyang 431-070South Korea Department of Internal Medicine Hallym University Sacred Heart Hospital of Hallym University Medical Center Seoul 134-701South Korea Department of Internal Medicine Hallym University Medical CenterChuncheon 200-704South Korea

AIM: To identify the factors that differentiate acute hepatitis B(AHB) from chronic hepatitis B with acute exacerbation(CHB-AE).METHODS: From 2004 to 2013, a total of 82 patients(male n = 52, 63.4%; female n = 30, 36.6%) with clinical features of acute hepatitis with immunoglobulin M antibodies to the hepatitis B core antigen(Ig M antiHBc) were retrospectively enrolled and divided into two groups; AHB(n = 53) and CHB-AE(n = 29). The AHB group was defined as patients without a history of hepatitis B virus(HBV) infection before the episode and with loss of hepatitis B surface antigen within 6 mo after onset of acute hepatitis. Biochemical and virological profiles and the sample/cutoff(S/CO) ratio of Ig M anti-HBc were compared to determine the differential diagnostic ***: The multivariate analysis demonstrated that, the S/CO ratio of Ig M anti-HBc and HBV DNA levels were meaningful factors. The S/CO ratio of Ig M anti-HBc was significantly higher in the AHB group, while the HBV DNA level was significantly higher in the CHB-AE group. The optimal cutoff values of Ig M anti-HBc and HBV DNA levels for differentiating the two conditions were 8 S/CO ratio and 5.5 log10 IU/m L, respectively. The sensitivity and specificity were 96.2% and 89.7% for the S/CO ratio of Ig M anti-HBc and 81.1% and 72.4% for HBV DNA levels, respectively. The area under receiver operating characteristic curves of both the S/CO ratio of Ig M anti-HBc and HBV DNA levels were not significantly different(0.933 vs 0.844, P = 0.105). When combining Ig M anti-HBc and HBV DNA, the diagnostic power significantly improved compared to HBV DNA alone(P = 0.0056). The combination of these factors yielded a sensitivity and specificity of 98.1% and 86.2%, ***: The combination of the S/CO ratio of Ig M anti-HBc and HBV DNA levels was a useful tool for differentiating AHB from CHB-AE in patients with positive Ig M anti-HBc.

关键词： Acute hepatitis Differential diagnosis Chronic hep

Neural Wiskott-Aldrich syndrome protein(N-WASP)promotes distant metastasis in pancreatic ductal adenocarcinoma via activation of LOXL2

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第4期32卷 615-624页

作者： HYUNG SUN KIM YUN SUN lee SEUNG myung DONG HYO JUNG KIM DA EUN lee HYEON WOONG KANG MYEONG JIN KIM JOON SEONG PARK Department of Surgery Gangnam Severance HospitalYonsei University College of MedicineSeoulKorea Department of Surgery Graduate School of Medical ScienceBrain Korea 21 ProjectYonsei University College of MedicineSeoulKorea Gibiome Co. Ltd.Gyeonggi-doKorea

Pancreatic ductal adenocarcinoma(PDAC)is one of the most aggressive solid malignancies.A specific mechanism of its metastasis has not been *** this study,we investigated whether Neural Wiskott-Aldrich syndrome protein(N-WASP)plays a role in distant metastasis of *** found that N-WASP is markedly expressed in clinical patients with *** analysis showed a notably more distant metastatic pattern in the N-WASP-high group compared to the N-WASP-low group.N-WASP was noted to be a novel mediator of epithelialmesenchymal transition(EMT)via gene expression profile *** of N-WASP in pancreatic cancer cells significantly inhibited cell invasion,migration,and *** also observed positive association of lysyl oxidase-like 2(LOXL2)and focal adhesion kinase(FAK)with the N-WASP-mediated response,wherein EMT and invadopodia function were *** N-WASP and LOXL2 depletion significantly reduced the incidence of liver and lung metastatic lesions in orthotopic mouse models of pancreatic *** results elucidate a novel role for N-WASP signaling associated with LOXL2 in EMT and invadopodia function,with respect to regulation of intercellular communication in tumor cells for promoting pancreatic cancer *** findings may aid in the development of therapeutic strategies against pancreatic cancer.

关键词： Pancreatic cancer Neural Wiskott-Aldrich syndrome protein(N-WASP)signaling Metastasis Epithelial-mesenchymal transition(EMT) Lysyl oxidase-like 2(LOXL2)

Crystallographically vacancy‐induced MOF nanosheet as rational single‐atom support for accelerating CO_(2)electroreduction to CO

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Carbon Energy 2024年第8期6卷 49-62页

作者： Jin Hyuk Cho Joonhee Ma Chaehyeon lee Jin Wook Lim Youngho Kim Ho Yeon Jang Jaehyun Kim myung‐gi Seo Youngheon Choi Youn Jeong Jang Sang Hyun Ahn Ho Won Jang Seoin Back Jong‐Lam lee Soo Young Kim Department of Materials Science and Engineering Korea UniversitySeoulRepublic of Korea Department of Chemical and Biomolecular Engineering Sogang UniversitySeoulRepublic of Korea Department of Materials Science and Engineering Pohang University of Science and Technology(POSTECH)PohangRepublic of Korea Department of Materials Science and Engineering Research Institute of Advanced MaterialsSeoul National UniversitySeoulRepublic of Korea Lotte Chemical R&D Center DaejeonRepublic of Korea Department of Chemical Engineering Hanyang UniversitySeoulRepublic of Korea School of Chemical Engineering and Material Science Chung‐Ang UniversitySeoulRepublic of Korea

To attain a circular carbon economy and resolve CO_(2)electroreduction technology obstacles,single‐atom catalysts(SACs)have emerged as a logical option for electrocatalysis because of their extraordinary catalytic *** SACs,metal–organic frameworks(MOFs)have been recognized as promising support materials because of their exceptional ability to prevent metal *** study shows that atomically dispersed Ni single atoms on a precisely engineered MOF nanosheet display a high Faradaic efficiency of approximately 100%for CO formation in H‐cell and three‐compartment microfluidic flow‐cell reactors and an excellent turnover frequency of 23,699 h−1,validating their intrinsic catalytic *** results suggest that crystallographic variations affect the abundant vacancy sites on the MOF nanosheets,which are linked to the evaporation of Zn‐containing organic linkers during ***,using X‐ray absorption spectroscopy and density functional theory calculations,a comprehensive investigation of the unsaturated atomic coordination environments and the underlying mechanism involving CO^(*)preadsorbed sites as initial states was possible and provided valuable insights.

关键词： 2‐dimensional material carbon dioxide reduction metal-organic frameworks single‐atom catalysts vacancy sites

Retinal artery/arteriole occlusion risks after endovascular treatment for unruptured intracranial aneurysm

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2024年第3期9卷 295-305,I0251-I0263页

作者： Hae Rang Kim Min Jeoung Kim Sunyeup Kim myung Soo Chang Dong Joon Kim Byung Moon Kim Keun Young Park Yong Bae Kim Christopher Seungkyu lee Suk Ho Byeon Sung Soo Kim Seung Won lee Yong Joon Kim Department of Ophthalmology CHA Bundang Medical CenterCHA University College of MedicineSeongnamKorea(the Republic of) Department of Neurosurgery Severance Stroke CenterSeverance HospitalYonsei University College of MedicineSeoulKorea(the Republic of) Department of Neurosurgery Uijeongbu St.Mary’s HospitalThe Catholic University of Korea College of MedicineUijeongbuKorea(the Republic of) Department of Medical AI Sungkyunkwan University School of MedicineSuwonKorea(the Republic of) Department of Ophthalmology Institute of Vision ResearchYonsei University College of MedicineSeoulKorea(the Republic of) Department of Radiology Severance Stroke CenterSeverance HospitalYonsei University College of MedicineSeoulKorea(the Republic of) Department of Precision Medicine Sungkyunkwan University School of MedicineSuwonKorea(the Republic of)

Background To evaluate the association between retinal artery/arteriole occlusion(RAO)and unruptured intracranial aneurysm(UIA).Methods Incident UIA patients from a nationwide cohort(n=253240)were categorised into three groups based on subsequent treatment:observation(n=208993),microsurgical clipping(n=14168)and endovascular treatment(EVT)groups(n=30079).The incidence and the incident time of RAO were *** of RAO and associated risk factors were ***,a hospital cohort comprising 2569 consecutive UIA patients treated at a tertiary hospital was analysed with detailed clinical information of *** In the nationwide cohort analysis,the incidence of RAO was significantly higher in EVT group than in observation and clipping groups,especially within 60 days(early RAO(within 60 days):HR=4.00,95%CI:2.44 to 6.56);delayed RAO(after 60 days:HR=1.74,95%CI:1.13 to 2.68).Multivariable analysis showed that the presence of chronic kidney disease(p=0.009)and use of a balloon microcatheter during the procedure(p=0.013)were associated with a higher risk of *** hospital cohort analysis,11(0.8%)cases of RAO occurred after EVT,whereas none occurred after microsurgical clipping(p<0.001).Patients with RAO were younger and received balloon microcatheters more frequently than their *** cases of RAO(90.9%)occurred in paraclinoid aneurysms,where EVT was preferred over microsurgical *** Performing EVT for UIA may increase the risk of subsequent *** should be taken when treating paraclinoid aneurysms with balloon microcatheters.

关键词： treatment nationwide balloon

Comparative study on discharge conditions in micro-hole electrical discharge machining of tungsten carbide (WC-Co) material

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国有色金属学会会刊：英文版 2009年第B9期19卷 114-118页

作者： Hyun-seok TAK Chang-Seung HA Dong-Hyun KIM Ho-Jun lee Hae-June lee myung-Chang KANG National Core Research Center for Hybrid Materials Solution Pusan National University Department of Electrical Engineering Pusan National University

WC-Co is used widely in die and mold industries due to its unique combination of hardness, strength and wear-resistance. For machining difficult-to-cut materials, such as tungsten carbide, micro-electrical discharge machining(EDM) is one of the most effective methods for making holes because the hardness is not a dominant parameter in EDM. This paper describes the characteristics of the discharge conditions for micro-hole EDM of tungsten carbide with a WC grain size of 0.5 μm and Co content of 12%. The EDM process was conducted by varying the condenser and resistance values. A R-C discharge EDM device using arc erosion for micro-hole machining was suggested. Furthermore, the characteristics of the developed micro-EDM were analyzed in terms of the electro-optical observation using an oscilloscope and field emission scanning electron microscope.

关键词：电火花加工碳化钨钴难切削材料硬质合金放电扫描电子显微镜微孔模具行业

Characteristic evaluation of Al_2O_3/CNTs hybrid materials for micro-electrical discharge machining

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 28-32页

作者： Hyun-seok TAK Chang-Seung HA Ho-Jun lee Hyung-Woo lee Young-Keun JEONG myung-Chang KANG National Core Research Center for Hybrid Materials Solution Pusan National University Department of Electrical Engineering Pusan National University

The characteristic evaluation of aluminum oxide （A1203）/carbon nanotubes （CNTs） hybrid composites for micro-electrical discharge machining （EDM） was described. Alumina matrix composites reinforced with CNTs were fabricated by a catalytic chemical vapor deposition method. A1203 composites with different CNT concentrations were synthesized. The electrical characteristic of A1203/CNTs composites was examined. These composites were machined by the EDM process according to the various EDM parameters, and the characteristics of machining were analyzed using field emission scanning electron microscope （FESEM）. The electrical conductivity has a increasing tendency as the CNTs content is increased and has a critical point at 5% A1203 （volume fraction）. In the machining accuracy, many tangles of CNT in A1203/CNTs composites cause violent spark. Thus, it causes the poor dimensional accuracy and circularity. The results show that conductivity of the materials and homogeneous distribution of CNTs in the matrix are important factors for micro-EDM of A1203/CNTs hybrid composites.

关键词： A1203/CNTs hybrid materials micro-electrical discharge machining micro-hole electrical conductivity