检索结果-南通市图书馆

Bioactive Compounds Recovery from Larrea tridentata by Green Ultrasound- Assisted Extraction

Phyton-International Journal of Experimental Botany 2024年第11期93卷 3091-3107页

作者： muyideen olaitan bamidele Jose Sandoval-Cortes Maria Liliana Flores-Lopez Olga Berenice Alvarez Perez Monica Lizeth Chavez Gonzalez Cristobal Noe Aguilar Bioprocesses and Bioproducts Research Group Food Research DepartmentSchool of ChemistryUniversidad Autonoma de CoahuilaSaltillo25070Mexico Centro de Investigacion e Innovacion Cientifica y Tecnologica Universidad Autonoma de CoahuilaSaltillo25070Mexico

Postharvest losses remain a signiﬁcant challenge,particularly in developing countries that have inadequate *** plants offer an eco-friendly and sustainable solution for managing diseases and pests in agri-cultural *** plants are rich in bioactive compounds,such as alkaloids,ﬂavonoids,terpenoids,phenolics,and essential oils,many of which have proven antimicrobial,antifungal,insecticidal,and antioxidant *** characteristics make medicinal plants viable candidates for postharvest disease and pest *** these,Larrea tridentata(creosote bush)is particularly notable for its bioactive compounds with strong antifungal *** potential applications include agriculture,food preservation,and *** study aimed to evaluate how different solvent mixtures affect the efﬁciency of ultrasound-assisted extraction,total polyphenol content,antioxidant capacity,and antifungal activity of *** leaves and ***ﬁndings revealed that the 60%ethanol ultrasound-assisted extract of *** leaves(ULL 60%)contained the highest concentration of bioactive compounds,including hydrolysable tannins(690.2 mg GAE/100 g)and condensed tan-nins(329.9 mg CE/100 g).All extracts demonstrated notable antioxidant activity in ABTS,DPPH,and FRAP assays,with ethanol-based extracts showing greater antioxidant potential than their aqueous *** terms of antifungal efﬁcacy,100%ethanol leaf extract exhibited the strongest inhibition against Fusarium oxyspor-um(60.03%),whereas 50%ethanol extract effectively inhibited Alternaria alternata(53.61%).Six major polyphe-nolic compounds were identiﬁed using reverse-phase high-performance liquid chromatography coupled with electrospray ionization mass spectrometry(RP-HPLC-ESI-MS).These include quercetin,luteolin,3,4-dihydrox-yphenylethanol,elenolic acid,nordihydroguaiaretic acid(NDGA),and *** compounds are known to have antibacterial,antifungal and antioxidant propert

关键词： Phytopathogens bioactive compounds desert plants Fusarium oxysporum Alternaria alternata

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Identification and Antibiotic Resistance Profile of Uropathogenic Bacteria from Sexually Active Women with Bacterial Vaginosis

引用

Journal of Biosciences and Medicines 2021年第11期9卷 52-67页

作者： Chinedum Taahie Oparaugo bamidele Abiodun Iwalokun Adesegun Abiola Adesesan Idowu Olaide Edu-muyideen Abimbola Modupe Adedeji Oliver Chukwujekwu Ezechi Mopelola Anotu Deji-Agboola Biochemistry & Nutrition Department Nigerian Institute of Medical Research Lagos Nigeria Department of Medical Microbiology & Parasitology Olabisi Onabanjo University Ago-Iwoye Nigeria Molecular Biology & Biotechnology Department Nigerian Institute of Medical Research Lagos Nigeria Central Research Laboratory Nigerian Institute of Medical Research Lagos Nigeria Microbiology Department Nigerian Institute of Medical Research Lagos Nigeria Monitoring & Evaluation Unit Nigerian Institute of Medical Research Lagos Nigeria Clinical Science Department Nigerian Institute of Medical Research Lagos Nigeria

Background: Urinary tract infections (UTIs) in women with bacterial vaginosis (BV) continue to pose tremendous health concerns and require appropriate use of antibiotics for effective case management. This study determined the prevalence, etiology and antibiotic resistance profile of uropathogenic bacteria isolated from sexually active women with BV in Lagos Nigeria. Method: A total of 258 sexually active women presenting with gynaecological complaints at the maternal and child unit of twenty Primary Health Care Centres in Lagos Nigeria from May 2017 to March 2018 were consecutively enrolled with consent. Bacterial vaginosis was diagnosed based on Amsel criteria. Midstream urine samples were collected aseptically, analyzed for bacterial pathogens and antibiotic susceptibility using standard microbiological methods. Results: BV was diagnosed in 184 (71.3%) with 69.2% also having UTI. Ninety four (36.4%) had UTI predominantly caused by Gram negative bacteria (96.8%). The organisms isolated were Escherichia coli 79 (84.0%), Klebsiella pneumoniae 5 (5.3%), Pseudomonas aeruginosa 4 (4.3%), Proteus mirabilis 3 (3.2%) and Staphylococcus saprophyticus 3 (3.2%). The pathogens elicited high resistance (66.7% - 100%) to tetracycline, amoxicillin-clavulanic acid, nitrofurantoin and cephalosporins, and moderate resistance (50%) to ofloxacin by P. aeruginosa strains. The isolates were susceptible (100%) to piperacillin-tazobactam and meropenem. Multi-drug resistance (MDR) was observed among 97.8% of the bacteria isolated. Conclusion: Findings from this study indicate high occurrence of UTI caused by MDR pathogens among sexually active women with BV with emerging evidence of poor clinical utility of nitrofurantoin and other commonly used first-line antibiotics against UTI. Further studies on non-bacterial aetiology of BV, molecular characterization of S. sa

关键词： Urinary Pathogens Antibiotics Susceptibility Bacterial Vaginosis Women

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Occurrence and Clinical Characteristics of Vaginitis among Women of Reproductive Age in Lagos, Nigeria

引用

Advances in Reproductive Sciences 2022年第4期10卷 91-105页

作者： Chinedum Taahie Oparaugo bamidele Abiodun Iwalokun Francisca Obiageri Nwaokorie Nathaniel Adeleke Okunloye Adesegun Abiola Adesesan Idowu Olaide Edu-muyideen Abimbola Modupe Adedeji Oliver Chukwujekwu Ezechi Mopelola Anotu Deji-Agboola Biochemistry & Nutrition Department Nigerian Institute of Medical Research Lagos Nigeria Department of Medical Microbiology & Parasitology Olabisi Onabanjo University Ago-Iwoye Nigeria Molecular Biology & Biotechnology Department Nigerian Institute of Medical Research Lagos Nigeria Central Research Laboratory Nigerian Institute of Medical Research Lagos Nigeria Department of Medical Laboratory Science College of Medicine University of Lagos Idi-Araba Lagos Nigeria Department of Biochemistry Faculty of Basic Medical Sciences College of Health Sciences Ladoke Akintola University of Technology Ogbomoso Nigeria Microbiology Department Nigerian Institute of Medical Research Lagos Nigeria Monitoring & Evaluation Unit Nigerian Institute of Medical Research Lagos Nigeria Clinical Science Department Nigerian Institute of Medical Research Lagos Nigeria

Background: Vaginitis is an important public health problem globally. It is associated with gynaecological and obstetric complications. Vulvovaginal candidiasis, bacterial vaginosis and trichomoniasis are mainly responsible for vaginitis. The aim of this study is to determine the occurrence, clinical characteristics and associated risk factors of vulvovaginal candidiasis and bacterial vaginosis among women of reproductive age attending Primary Health Care centres in Lagos Nigeria. Methods:This cross-sectional study recruited 258 women with genital complaints after obtaining their informed written consent between May 2017 and March 2018. Structured questionnaires were administered and high vaginal swabs were collected for laboratory examination. The results were analysed with descriptive statistics, chi-square and simple logistic regression. Results: Out of the 210 (81.4%) of the women with one or more vaginal infections, 105 (50.0%), 26 (12.4%) had bacterial vaginosis, and vulvovaginal candidiasis respectively while 78 (37.1%) had both vulvovaginal candidiasis and bacterial vaginosis. Only 1 (0.5%) participant had trichomoniasis and bacterial vaginosis. History of abortion and age below 25 years were associated with vulvovaginal candidiasis while pregnancy, history of miscarriage, age at first sexual activity and discharge were associated with bacterial vaginosis. Itching was associated with both vulvovaginal candidiasis and bacterial vaginosis. Conclusion: This study revealed vulvovaginal candidiasis and bacterial vaginosis as important cause of genital complaints among reproductive age women in Lagos. Health education, robust diagnosis and early treatment are needed in order to reduce the associated risk factors, disease burden and complications.

关键词： Vaginitis Women Reproductive Age

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：