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EFFECT OF TOURISM ON THE DISTRIBUTION OF LARVAL BLACKFLIES (DIPTERA：SIMULIUM) IN PALNI HILLS OF SOUTH INDIA

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水生生物学报 2011年第4期35卷 688-692页

作者： Sankarappan Anbalagan Sundaram Dinakaran Jeyaraj Pandiarajan muthukalingan krishnan Department of Environmental Biotechnology Bharathidasan University Tiruchirappalli-620024 Tamil Nadu India Centre for Research in Aquatic Entomology The Madura College Madurai-625016 Tamil Nadu India

The effect of tourism on the distribution of larval blackflies during three different seasons of Palni hills was *** streams were selected(Kumbakkarai,Moolayar,Kurusedi,Silver cascade Pampar and Guntar) for this study,of which,three streams(Silver cascade Pampar and Guntar) were in peak of Palni hills(Kodaikanal town areas) and easy access to the *** remaining three streams(Kumbakkarai,Moolayar and Kurusedi) were in downhill *** physico-chemical and stream parameters analyses indicated that the most tourist accessible site of Silver cas-cade stream had poor water quality and the predominant of larval blackfly population when compared to other sampling *** highest population of larval blackflies was observed during winter followed by summer and northeast *** the effect of tourism causes pollution to streams,which in turn to promote the population of blackfly larvae and affect the other insect community in streams.

关键词：英文摘要内容介绍编辑工作盘尾丝虫

家蚕末龄幼虫、蛹和成虫期载脂蛋白组成的变化(英文)

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昆虫学报 2017年第3期60卷 247-253页

作者： Thangaraj PRATHEEP Neelamegam RAMESHKUMAR Nagarajan KAYALVIZHI Thangaiyan SUGANYA Sivashanmugam KARTHIKEYAN muthukalingan krishnan Department of Environmental Biotechnology Bharathidasan University Tiruehirappalli-620024 India Department of Zoology Periyar University Salem-636011 India School of Bio Sciences & Technology VIT University Vellore-632014 India

【目的】载脂蛋白是一种重要的血淋巴脂蛋白,它将90%的脂类输送到内部器官。本研究旨在调查家蚕Bombyx mori各个发育期血淋巴载脂蛋白组成变化。【方法】采用溴化钾密度梯度超离心、肝素钠沉淀(heparin sodium precipitation)和连接蒸... 详细信息

【目的】载脂蛋白是一种重要的血淋巴脂蛋白,它将90%的脂类输送到内部器官。本研究旨在调查家蚕Bombyx mori各个发育期血淋巴载脂蛋白组成变化。【方法】采用溴化钾密度梯度超离心、肝素钠沉淀(heparin sodium precipitation)和连接蒸发光散射检测器的高效液相色谱(high performance liquid chromatography coupled with evaporative light scattering detector,HPLC-ELSD)等方法,检测了家蚕各个发育期血淋巴脂蛋白组成变化。【结果】从5龄幼虫到成虫的转变过程中,从幼虫期和吐丝期家蚕中分离的载脂蛋白密度分别为1.130和1.139 g/mL,但蛹期载脂蛋白密度降低(为1.083 g/mL)。应用肝素钠沉淀法对载脂蛋白组成的分析表明,家蚕吐丝期载脂蛋白主要是高密度载脂蛋白(9.8μg/μL);从吐丝期开始,低密度载脂蛋白含量增加,并在蛹期持续存在(4.2μg/μL)。在所有发育期,载脂蛋白Ⅲ含量低,在2日龄蛹中含量最高(4.0μg/μL)。另外,从吐丝期至成虫期,总脂浓度逐渐增加,从1.4μg/μL增加至3.8μg/μL。通过HPLC-ELSD对中性脂组成的分析表明,在所有发育期只含有微量的单酰甘油(<0.04μg/μL),在5龄幼虫中期至蛹期末观察到二酰甘油(0.11~0.61μg/μL),在蛹期发现三酰甘油(0.18~1.02μg/μL)。【结论】总体结果说明,在幼虫期和吐丝期,高密度载脂蛋白主要运输二酰甘油;化蛹后,高密度载脂蛋白更多地与三酰甘油有关,而与二酰甘油相关性小,并与载脂蛋白Ⅲ形成低密度载脂蛋白有关。这些结果提示载脂蛋白的转变是一个精确的时间控制过程。

关键词：家蚕载脂蛋白高密度载脂蛋白低密度载脂蛋白脂类

A simple and cost-effective protocol for extraction of genomic DNA from ethanol preserved black flies(Simuliidae:Diptera)

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Journal of Coastal Life Medicine 2016年第9期4卷 721-725页

作者： Neelamegam Rameshkumar Sankarappan Anbalagan Nagarajan Kayalvizhi Rasiravuthanahalli Kaveriyappan Govindarajan Vimalanathan Arun Prasanna muthukalingan krishnan Department of Environmental Biotechnology Bharathidasan UniversityTiruchirappalli 620024Tamil NaduIndia Department of Zoology Sethupathy Government Arts CollegeRamanathapuram 623502Tamil NaduIndia Department of Zoology Periyar UniversitySalem 636001Tamil NaduIndia

Objective:To investigate the efficacy of extraction methodology for the proposed DNA from the ethanol preserved black flies(Simuliidae:Diptera).Methods:This study addressed a simple and effective protocol for extraction of DNA from black flies stored in the *** sizes of larval and adult black flies ranged from 1.5 to 2.5 mm and 3 to 7 mm,*** demonstrate the efficacy of the proposed methodology,the DNA was extracted from the ethanol preserved sample of black flies using the commercial *** extracted DNA was further validated in the PCR amplification using internal transcribed spacer-1 rDNA and cytochrome oxidase subunit II rDNA target ***:Interestingly,a minor modification in the proposed methodology yielded a good DNA concentration in comparison with the commercial *** extracted DNA sample using the proposed methodology was successfully validated in the PCR amplification using internal transcribed spacer-1 rDNA and cytochrome oxidase subunit II rDNA ***:The proposed DNA extraction procedure yielded good concentration of DNA from the ethanol preserved black *** added advantage is that the procedure is suitable for a range of insect species preserved in the ethanol obtained from the various field conditions.

关键词： Black flies Ethanol preservation DNA extraction PCR Amplification

Proton pump inhibitors and all-cause mortality risk among cancer patients

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World Journal of Clinical Oncology 2025年第1期16卷 34-42页

作者： Arunkumar krishnan Carolin Victoria Schneider Declan Walsh Department of Supportive Oncology Atrium Health Levine CancerCharlotteNC 28204United States Department of Medicine Section of Hematology and OncologyWake Forest University School of MedicineWinston-SalemNC 27101United States Department of Medicine Ⅲ GastroenterologyMetabolic Diseasesand Intensive CareUniversity Hospital RWTH AachenAachen 52074Germany

BACKGROUND Proton pump inhibitors(PPIs)are widely used,including among cancer patients,to manage gastroesophageal reflux and other gastric acid-related *** evidence suggests associations between long-term PPI use and higher risks for various adverse health outcomes,including greater *** To investigate the association between PPI use and all-cause mortality among cancer patients by a comprehensive analysis after adjustment for various confounders and a robust methodological approach to minimize *** This retrospective cohort study used data from the TriNetX research network,with electronic health records from multiple healthcare *** study employed a new-user,active comparator design,which compared newly treated PPI users with non-users and newly treated histamine2 receptor antagonists(H2RA)users among adult cancer *** prescribed PPIs(esomeprazole,lansoprazole,omeprazole,pantoprazole,or rabeprazole)users were compared to non-users or newly prescribed H2RAs(cimetidine,famotidine,nizatidine,or ranitidine)*** primary outcome was all-cause *** patient in the main group was matched to a patient in the control group using 1:1 propensity score matching to reduce confounding *** Cox regression models were used to estimate hazard ratios(HRs)and 95% confidence interval(CI).RESULTS During the follow-up period(median 5.4±1.8 years for PPI users and 6.5±1.0 years for non-users),PPI users demonstrated a higher all-cause mortality rate than non-users after 1 year,2 years,and at the end of follow up(HRs:2.34-2.72).Compared with H2RA users,PPI users demonstrated a higher rate of all-cause mortality HR:1.51(95%CI:1.41-1.69).Similar results were observed across sensitivity analyses by excluding deaths from the first 9 months and 1-year post-exposure,confirming the robustness of these *** a sensitivity analysis,we analyzed all-cause mortality outcomes between former PPI users and individual

关键词： All-cause mortality Cancer Histamine-2 receptor antagonists Mortality Malignancy Proton pump inhibitors Carcinoma Outcome

Comparative Evaluation and Performance Analysis of Heat Exchangers Featured with Peened Surface

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Journal of Thermal Science 2025年第1期 50-61页

作者： DINESHBABU Chinnadurai SHIVA SANKARAN Nallasamy VENKATESH RAJA krishnan VENKATESH Rathinavelu Department of Mechanical Engineering Kongunadu College of Engineering and Technology Department of Mechanical Engineering Selvam College of Technology Department of Mechanical Engineering Sona College of Technology Department of Mechanical Engineering Saveetha School of EngineeringSaveetha Institute of Medical and Technical Sciences (SIMATS)Saveetha University

Heat exchangers have the potential for various engineering applications,and their performance is enriched by surface *** proposed system enriches the heat exchanger's performance by adapting a peened stainless steel（SS） surface blasted with copper,grinding,sand,and *** influences peened SS surface modified with a copper blast,grinding,sandblast,and iron blast on the surface morphology of shell and tube heat exchanger surface（STHE） is analyzed via tungsten heated cathode electron gun featured scanning electron microscope and observed coarse grain *** SS surface featured STHE performance is experimentally evaluated by different flow rates（30,60,90,and 120 L/min） underwater fluid medium functioned by the temperature ranges of 25-75℃ and its results are compared with computational fluid dynamic（CFD）/heat transfer research（HTRI） analyzed *** 60 L/min flow rate was spotted as an optimum value for both shell and tube side *** STHE is operated with a 60 L/min flow rate under the different peened surfaces and evaluated its Stanton number,Nusselt number,logarithmic mean temperature difference（LMTD）,overall heat transfer coefficient,number of transfer units（NTU）,effectiveness,and exergy *** iron blasted SS peened surface was observed to have better SHTE performance like Stanton number（0.0012）,Nusselt number（2180）,reduced LMTD of 31℃,improved overall heat transfer co-efficient of 2400 W/（m2·K）,better NTU of 0.5532,good effectiveness value of 0.451 62,and hiked exergy efficiency of 10% respectively.

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Streptomyces ghanaensis VITHM1 mediated green synthesis of silver nanoparticles： Mechanism and biological applications

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Frontiers of Chemical Science and Engineering 2016年第4期10卷 542-551页

作者： Mani Abirami krishnan Kannabiran Biomolecules and Genetic Division School of Biosciences and Technology VIT University Tamil Nadu 623014 India

We present the microbial green synthesis of silver nanoparticles （hiPs） by Streptomyces ghanaensis VITHM1 strain （MTCC No. 12465）. The secondary metabolites in the cell free supernatant of this bacterium when incubated with 1 mmol/L AgNO3, mediated the biological synthesis of AgNPs. The synthesized AgNPs were characterized by UV-visible spectrum, X-ray diffrac- tion （XRD）, atomic force microscope, scanning electron microscopy equipped with energy dispersive spectroscopy, transmission electron microscopy, FT-IR spectroscopy, dynamic light scattering and zeta potential. They were highly stable and, spherical in shape with the average size of 30-50 nm. The secondary metabolites involved in the formation of AgNPs were identified gas chromatographymass spectrography. The 3D structure of the unit cell of the synthesized AgNPs was determined using XRD data base. The synthesized AgNPs exhibited significant antibacterial activity against tested bacterial pathogens, and did not show haemolysis on human red blood cells. This green synthesis could provide a new platform to explore and use AgNPs as antibacterial therapeutic agents.

关键词： Streptomyces ghanaensis VITHM1 nanopar-ticles 3D structure antibacterial activity

Contrast Enhancement Based Image Detection Using Edge Preserved Key Pixel Point Filtering

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Computer Systems Science & Engineering 2022年第8期42卷 423-438页

作者： Balakrishnan Natarajan Pushpalatha krishnan Department of Master of Computer Applications Sona College of TechnologySalem–636005India Department of Computer Applications SRM Institute of Science and TechnologyRamapuramChennai600089India

In existing methods for segmented images,either edge point extraction or preservation of edges,compromising contrast images is so sensitive to *** Degeneration Threshold Image Detection(DTID)framework has been proposed to improve the contrast of edge filtered ***,DTID uses a Rapid Bilateral Filtering process for filtering edges of contrast *** filter decomposes input images into base layers in the DTID *** minimal filtering time,Rapid Bilateral Filtering handles high dynamic contrast images for smoothening edge *** the DTID framework,Rapid Bilateral Filtering with Shift-Invariant Base Pass Domain Filter is insensitive to *** Shift-Invariant Filtering estimates value across edges for removing outliers(i.e.,noise preserving base layers of the contrast image).The intensity values are calculated in the base layer of the contrast image for accurately detecting nearby spatial locations using Shift-Invariant base Pass Domain Filter(SIDF).At last,Affine Planar Transformation is applied to detect edge filtered contrast images in the DTID framework for attaining a high quality of the *** normalizes the translation and rotation of *** this,Degeneration Threshold Image Detection maximizes average contrast enhancement quality and performs an experimental evaluation of factors such as detection accuracy,rate,and filtering time on contrast *** analysis shows that the DTID framework reduces the filtering time taken on contrast images by 54%and improves average contrast enhancement quality by 27%compared to GUMA,HMRF,SWT,and *** provides better performance on the enhancement of average contrast enhancement quality by 28%,detection accuracy rate by 26%,and reduction in filtering time taken on contrast images by 30%compared to state-of-art methods.

关键词： Rapid bilateral filtering edge preserved filtering affine planar transformation key pixel point localization shift-invariant base pass domain filter

Controllability results for damped second-order impulsive neutral integrodifferential systems with nonlocal conditions

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控制理论与应用（英文版） 2013年第2期11卷 186-192页

作者： Ganesan ARTHI krishnan BALACHANDRAN Department of Mathematics Bharathiar University

In this paper, we establish a set of sufficient conditions for the controllability of damped second-order impulsive neutral integrodifferential systems with nonlocal initial conditions in Banach spaces. The approach used is the Sadovskii fixed point theorem combined with a noncompact condition on the cosine family of operators. An example is oresented to illustrate the result.

关键词： Controllability Damped second-order differential equations Impulsive differential equations Neutralintegrodifferential equations Nonlocal conditions

Review on mechanism and process of surface polishing using lasers

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Frontiers of Mechanical Engineering 2019年第3期14卷 299-319页

作者： Arun krishnan Fengzhou FANG Centre of Micro/Nano Manufacturing Technology (MNMT-Dublin) University College Dublin Dublin 4 Ireland State Key Laboratory of Precision Measuring Technology and Instruments Centre of Micro/Nano Manufacturing Technology (MNMT) Tianjin University Tianjin 300072 China

Laser polishing is a technology of smoothening the surface of various materials with highly intense laser beams. When these beams impact on the material surface to be polished, the surface starts to be melted due to the high temperature. The melted material is then relocated from the ‘peaks to valleys’ under the multidirectional action of surface tension. By varying the process parameters such as beam intensity, energy density, spot diameter, and feed rate, different rates of surface roughness can be achieved. High precision polishing of surfaces can be done using laser process. Currently, laser polishing has extended its applications from photonics to molds as well as bio-medical sectors. Conventional polishing techniques have many drawbacks such as less capability of polishing freeform surfaces, environmental pollution, long processing time, and health hazards for the operators. Laser polishing on the other hand eliminates all the mentioned drawbacks and comes as a promising technology that can be relied for smoothening of initial topography of the surfaces irrespective of the complexity of the surface. Majority of the researchers performed laser polishing on materials such as steel, titanium, and its alloys because of its low cost and reliability. This article gives a detailed overview of the laser polishing mechanism by explaining various process parameters briefly to get a better understanding about the entire polishing process. The advantages and applications are also explained clearly to have a good knowledge about the importance of laser polishing in the future.

关键词： laser polishing surface roughness process parameters mechanism