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Photobiomodulation:a novel approach to promote trans-differentiation of adipose-derived stem cells into neuronal-like cells

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Neural Regeneration Research 2025年第2期20卷 598-608页

作者： daniella da Silva Madeleen Jansen van Rensburg Anine Crous Heidi Abrahamse Laser Research Centre Faculty of Health SciencesUniversity of JohannesburgDoornfonteinJohannesburgSouth Africa

Photobiomodulation,originally used red and near-infrared lasers,can alter cellular *** has been demonstrated that the visible spectrum at 451-540 nm does not necessarily increase cell proliferation,near-infrared light promotes adipose stem cell proliferation and affects adipose stem cell migration,which is necessary for the cells homing to the site of *** this in vitro study,we explored the potential of adipose-derived stem cells to differentiate into neurons for future translational regenerative treatments in neurodegenerative disorders and brain *** investigated the effects of various biological and chemical inducers on trans-differentiation and evaluated the impact of photobiomodulation using 825 nm near-infrared and 525 nm green laser light at 5 J/*** adipose-derived stem cells can be used in autologous grafting and photobiomodulation has been shown to have biostimulatory *** findings reveal that adipose-derived stem cells can indeed trans-differentiate into neuronal cells when exposed to inducers,with pre-induced cells exhibiting higher rates of proliferation and trans-differentiation compared with the control ***,green laser light stimulation led to notable morphological changes indicative of enhanced trans-differentiation,while near-infrared photobiomodulation notably increased the expression of neuronal *** biochemical analysis and enzyme-linked immunosorbent assays,we observed marked improvements in viability,proliferation,membrane permeability,and mitochondrial membrane potential,as well as increased protein levels of neuron-specific enolase and ciliary neurotrophic ***,our results demonstrate the efficacy of photobiomodulation in enhancing the trans-differentiation ability of adipose-derived stem cells,offering promising prospects for their use in regenerative medicine for neurodegenerative disorders and brain injuries.

关键词： differentiation inducers green photobiomodulation immortalized adipose-derived stem cell near-infrared photobiomodulation neurodegenerative disease neurogenesis photobiomodulation trans-differentiation

Estimation of hydraulic parameters from pumping tests in a multiaquifer system

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Underground Space 2020年第3期5卷 210-222页

作者： da.ha.Gang Zheng haizuo Zhou Chaofeng Zeng Huihui Zhang School of Civil Engineering Tianjin UniversityTianjin 300072China Key Laboratory of Coast Civil Structure Safety of Ministry of Education Tianjin UniversityTianjin 300072China Hunan Provincial Key Laboratory of Geotechnical Engineering for Stability Control and Health Monitoring School of Civil EngineeringHunan University of Science and TechnologyXiangtanHunan 411201China School of Resources and Environmental Sciences Wuhan UniversityWuhan 430079China

The hydrogeologic conditions in Tianjin,China,are characterized by a system of multiple alternating aquifers and aquitards and a high groundwater ***,the groundwater system to a depth of 70 m includes one phreatic aquifer and three semiconfined aquifers(AqI–AqIII).The distribution of aquifers varies *** estimates of aquifer parameters from pumping tests are essential in geotechnical engineering *** this study,the applicability of different models for estimating hydraulic parameters in a multiaquifer system is *** avoid errors in the graphic-analytical process and to enhance the efficiency and accuracy,a hybrid algorithm,called GALMA(a genetic algorithm(GA)combined with the Levenberg–Marquardt(LM)algorithm),is used with the Neuman and Witherspoon model and ratio *** estimated values in the second and third semiconfined aquifers(AqII and AqIII)from various solutions are compared with the measured *** validations based on the prediction of the drawdown values are performed via a three dimensional numerical simulation.

关键词： Hydraulic parameter Leaky aquifer Pumping test Optimal approach

Non-expansive Mappings and Iterative Methods in Uniformly Convex Banach Spaces

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Acta Mathematica Sinica,English Series 2004年第5期20卷 829-836页

作者： ha|YunZHOU Dept.ofMath. ShijiazhuangMechanicalEngineeringCollegeShijiazhuang050003P.R.China

In this article,we will investigate the properties of iterative sequence for non-expansive mappings and present several strong and weak convergence results of successive approximations to fixed points of non-expansive mappings in uniformly convex Banach *** results presented in this article generalize and improve various ones concerned with constructive techniques for the fixed points of non-expansive mappings.

关键词： Non-expansive mapping Mann and lshikawa iteration schemes Convergence theorem Uniformly convex Banach space

Effects of Material and Dimension on TCF,Frequency,and Q of Radial Contour Mode AlN-on-Si MEMS Resonators

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Journal of Electronic Science and Technology 2021年第4期19卷 319-334页

作者： Thi Dep ha with the Faculty of Electronics Technology Industrial University of Ho Chi Minh CityHo Chi Minh City 70000

This paper investigates the effects of material and dimension parameters on the frequency splitting,frequency drift,and quality factor(Q)of aluminium nitride(AlN)-on-n-doped/pure silicon(Si)microelectromechanical systems(MEMS)disk resonators through analysis and *** parameters include the crystallographic orientation,dopant,substrate thickness,and *** resonators operate in the elliptical,higher order,and flexural *** simulation results show that i)the turnover points of the resonators exist at 55°C,-50°C,40°C,and-10°C for n-doped silicon with the doping concentration of 2×1019 cm-3 and the Si thickness of 3.5μm,and these points are shifted with the substrate thickness and mode variations;ii)compared with pure Si,the modal-frequency splitting for n-doped Si is higher and increases from 5%to 10%for all studied modes;iii)Q of the resonators depends on the temperature and ***,the turnover,modal-frequency splitting,and Q of the resonators depend on the thickness and material of the substrate and the *** work offers an analysis and design platform for high-performance MEMS gyroscopes as well as oscillators in terms of the temperature compensation by n-doped Si.

关键词： Anisotropic contour mode doping gyroscope microelectromechanical systems(MEMS)resonator piezoelectric temperature coefficient of frequency(TCF) temperature compensation thin-film piezoelectric-on-substrate(TPoS)

High-performance colorful semitransparent perovskite solar cells with phase-compensated microcavities

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nano Research 2018年第5期11卷 2553-2561页

作者： Kyu-Tae Lee Ji-Yun Jang na Young ha Soonil Lee Hui Joon Park Department of Materials Science and Engineering University of Illinois Urbana Illinois 61801 USA Department of EnergySystems Research Ajou University Suwon 16499 Republic of Korea Department of Electrical and Computer Engineering Ajou University Suwon 16499 Republic of Korea

We demonstrate highly efficient multi-colored semitransparent perovskite solar cells that can create high angular tolerant controllable transmissive colors up to 60~, based on phase-compensated microcavities. The efficiency of the semitransparent colors was improved by impedance matching, which was enabled by placing a dielectric functional layer on top of traditional optical microcavities, with negligible influence on color pureness. The vast majority of the visible part of solar radiation is efficiently utilized for solar energy harvesting, achieving 10.47%, 10.66%, and 11.18% of efficiency for red, green, and blue （RGB） colored solar cells, respective136 while a very small proportion of the visible solar spectrum is used for structural coloration that can be readily tuned by altering the cavity medium thickness. The approach described herein can be suitable for a variety of applications such as display systems with ultra-low power consumption, highly efficient colorful solar panels, low-power wearable electronics, and energy-efficient optoelectronics.

关键词： perovskite solar cells semitransparency color filters optical cavities

Development of a coupled supersonic inlet-fan navier–Stokes simulation method

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Chinese Journal of Aeronautics 2018年第2期31卷 237-246页

作者： Qiushi LI Yongzhao LYU Tianyu PAN da LI ha'nan LU Yifang GONG national Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics Beihang UniversityBeoing 100191 China School of Energy and Power Engineering Beihang University Beijing 100083 China Collaborative Innovation Center of Advanced Aero-Engine Beihang University Beijing 100083 China GL-Turbo Compressor Company Wuxi 214106 China

A coupled supersonic inlet-fan navier–Stokes simulation method was developed by using COMSOL-CFD code. The flow turning, pressure rise and loss effects across blade rows of the fan and the inlet-fan interactions were taken into account as source terms of the governing equations without a blade geometry by a body force model. In this model, viscous effects in blade passages can also be calculated directly, which include the exchange of momentum between fluids and detailed viscous flow close to walls. naSA Rotor 37 compressor test rig was used to validate the ability of the body force model to estimate the real performance of blade rows. Calculated pressure ratio characteristics and the distribution of the total pressure, total temperature, and swirl angle in the span direction agreed well with experimental and numerical data. It is shown that the body force model is a promising approach for predicting the flow field of the turbomachinery. Then, coupled axisymmetric mixed compression supersonic inlet-fan simulations were conducted at Mach number 2.8 operating conditions. The analysis includes coupled steady-state performance, and effects of the fan on the inlet. The results indicate that the coupled simulation method is capable of simulating behavior of the supersonic inlet-fan system.

关键词： Body force model Coupled simulation Rapid numerical method Supersonic inlet-fan Viscous flow

THE STUDY ON NOVEL MICROELECTRODE ARRAY CHIPS FOR THE DETECTION OF HEAVY METALS IN WATER POLLUTION

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Journal of Innovative Optical Health Sciences 2012年第1期5卷 11-17页

作者： HUI-XIN ZhaO WEI CAI da.ha.haO WAN PING WANG Biosensor national Special Laboratory Key Laboratory for Biomedical Engineering of Education Ministry Department of Biomedical Engineering Zhejiang University Hangzhou 310027P.R.China

Qualitative and quantitative analysis of trace heavy metals in aqueous environment are rapidly assuming significance along with the rapid development of *** this paper,gold microelectrode array(MEA)plated with mercury film was used for simultaneous voltammetric detection of zinc,cadmium,lead and copper ions in *** electrochemical behavior and the actual surface area of the MEA were investigated by cyclic voltammetry in K_(3)[Fe(CN)_(6)].Electrochemical impedance spectrum(EIS)was utilized to examine the deposition of mercury on the electrode *** on anodic stripping voltammetry,mercury filmAu MEA was applied to the detection of heavy metals in artificial analyte,where good calibrate linearity was obtained for cadmium,lead and copper ions,but with zinc exhibiting poor linearity.

关键词： Microelectrode array(MEA)chip heavy metals detection water pollution

Current state-of-the-art review of footwear–ground friction

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Friction 2024年第10期12卷 2188-2204页

作者： david REBENda Tomáš SÁha Footwear Research Centre University InstituteTomas Bata University in ZlinZlin 76001Czech Republic Faculty of Mechanical Engineering Brno University of TechnologyBron 61600Czech Republic

The most important role of footwear is to ensure safe,functional walking,and foot *** the proper functionality of not only the work shoes,the anti-slip behavior of the shoe under various conditions and environments plays an important role in the prevention of slips,trips,falls,and consequent *** article is intended to review the current understanding of the frictional mechanisms between shoe outsoles and various counterfaces that impact the evaluation of outsole *** research focuses on the mechanisms driving outsole friction on different ground surfaces or the definition and description of parameters that influence outsole ***,the review discusses the effect of various surface contaminants on footwear ***,challenges and outlooks in the field of footwear outsoles are briefly mentioned.

关键词： shoe outsole composite slipperiness coefficient of friction(COF) adhesion safe walk

Some remarks on the genericity of unique range sets for meromorphic functions

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Science China Mathematics 2005年第z1期48卷 262-267页

作者： ha Huy Khoai Institute of Mathematics 18 Hoang Quoc Viet 10307HanoiVietnam

In this paper we relate the study of unique range sets for meromorphic functions (URSM) with the hyperbolic hypersurfaces and give some remarks on the genericity of unique range sets for meromorphic functions.

关键词： unique range set for meromorphic functions, hyperbolic surface.