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Effect of torsional mode phacoemulsification on cornea in eyes with/without pseudoexfoliation

International Journal of Ophthalmology(English edition) 2015年第2期8卷 281-287页

作者： Süleyman Demircan mustafa atas Yusufcan Yurtsever Eye Clinic Kayseri Training and Research Hospital

AIM: To evaluate the effect of torsional mode phacoemulsification on central corneal thickness, corneal endothelial cell density, and morphology in eyes with/without pseudoexfoliation(PEX) ***: Fourty-two consecutive patients with and42 patients without PEX as a control group scheduled for cataract surgery was studied. Phacoemulsification, using OZi L IP system, was performed with quick chop technique. Using noncontact specular microscopy, the central endothelial cell density(ECD), coefficient of variation, percentage of hexagonal cells, and the central corneal thickness(CCT) were evaluated preoperatively and postoperatively at 1, 7 and 30 ***: The ECD in PEX syndrome was statistically significantly lower than that in the control group preoperatively and postoperatively(P ≤0.001).Percentage change in ECD was statistically significantly higher in PEX than that in control group after surgery follow up(P ≤0.04).There was no statistically significant difference between both groups comparing percentage of hexagonal cells and coefficient of variation in the cell size before and after the surgery. At 1 and 7d after surgery, percentage change in CCT was statistically significantly higher in PEX group than that in the control group(P ≤0.041).CONCLUSION: Although torsional mode phacoemulsification and intraocular lens(IOL) implantation provided a safe and favorable surgical outcome in patients with/without PEX, torsional phacoemulsification led to significantly higher ECD loss in the PEX group than that in the control group during the whole follow up *** addition, more corneal swelling in the PEX group than that in the control group during the early postoperative period has indicated that the corneal endothelium, in presence of PEX endotheliopathy, seems to be more susceptible to the effects of phacoemulsification surgeryin eyes with PEX. The increased risk of anterior chamber manipulations in patients with PEX should be taken into account for an incr

关键词： pseudoexfoliation syndrome endothelial cell density endothelial morphology torsional mode phacoemulsification corneal endothelium

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Comparison of 45- degree Kelman and 45- degree balanced phaco tip designs in torsional microcoaxial phacoemulsification

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International Journal of Ophthalmology(English edition) 2015年第6期8卷 1168-1172页

作者： Süleyman Demircan mustafa atas Emre Goktas Burhan Baskan Eye Clinic Kayseri Training and Research Hospital

AIMTo compare the intraoperative performance and postoperative outcome after microcoaxial torsional phacoemulsification using either a Kelman or balanced phaco *** were treated using 2.2 mm microcoaxial torsional phacoemulsification using either a 45-degree mini-flared Kelman® or a 45-degree Intrepid® Balanced phaco tip. Intraoperative measurements included total ultrasound (US) time, cumulative dissipated energy (CDE), torsional US time, and balanced salt solution (BSS) use. The central endothelial cell density (ECD) and central corneal thickness (CCT) were evaluated preoperatively and postoperatively 1, 7, and 30d after surgery using noncontact specular *** 116 enrolled eyes (116 patients) were divided equally between the Kelman and balanced tip groups. Intraoperative measurements showed significantly less total US time, torsional US time, CDE, and BSS use in the balanced group than in Kelman group (P<0.05). The total US time, torsional US time, CDE, and BSS use were 17.45±14.53s, 16.63±13.97s, 6.38±5.26, and 48.21±17.21 mL in the Kelman group and 11.39 ± 9.60s, 10.90 ± 9.25s, 4.04 ± 3.42, and 41.36 ± 12.70 mL in the balanced group, *** phacoemulsification performed with a balanced tip provided more effective lens removal with less total US time, torsional time, CDE, and BSS use, as well as similar changes in ECD with a Kelman tip in all cataract grades. This special designed phaco tip for torsional phacoemulsification provides an alternative phaco tip for many surgeons' preference with straight phaco tip.

关键词： phaco tip torsional phacoemulsification Kelman phaco tip balanced phaco tip

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Measurement of choroidal thickness and macular thickness during and after pregnancy

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International Journal of Ophthalmology(English edition) 2015年第2期8卷 321-325页

作者： DondüMelek Ulusoy Necati Duru mustafa atas Hasan Altinkaynak Zeynep Duru Gokhan Acmaz Department of Ophthalmology Kayseri Education and Research Hospital Department of Ophthalmology Ankara Atatürk Education and Research Hospital Department of Ophthalmology Ankara Numune Education and Research Hospital Department of Obstetrics and Gynecology Kayseri Education and Research Hospital

OBJECTIVE:To investigate the effect of pregnancy on subfoveal choroidal thickness (SFCT) and macular thickness in both pregnant and not pregnant healthy women.;METHODS:Twenty-nine healthy pregnant women in their third trimester and 36 age-matched healthy women were enrolled in a prospective, cross-sectional study. Foveal and parafoveal thickness in the four quadrants and SFCT were measured by optical coherence tomography (OCT) in the healthy pregnant women (i.e. study group) and healthy women (i.e. control group). OCT measurements were again measured 3mo after delivery in the study group.;RESULTS:Mean SFCT measurements in the control group, pregnant women of the study group, and after delivery of the study group were 320.86±59.18 µm, 387.97±59.91 µm, and 332.40±26.03 µm, respectively. There was a statistically significant difference in the mean SFCT values between pregnant women of the study group and the control group (P=0.000). Foveal and parafoveal thickness values were not statistically significant in either the study or control group.;CONCLUSIONS:SFCT increases during pregnancy and returns to normal range in the three months after delivery. Macular thickness does not show any change during pregnancy.

关键词： choroidal thickness enhanced depth imaging optical coherence tomography foveal thickness pregnancy

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Comparison of corneal endothelial changes following phacoemulsification with transversal and torsional phacoemulsification machines

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International Journal of Ophthalmology(English edition) 2014年第5期7卷 822-827页

作者： mustafa atas Süleyman Demircan Arzu Seyhan Karatepe Hashas Ahmet Gülhan Gkmen Zararsιz Department of Ophthalmology and Vision Sciences Kayseri Traning and Research Hospital Department of Biostatistics Faculty of MedicineErciyes University

AIM:To compare and evaluate the phacoemulsification parameters and postoperative endothelial cell changes of two different phacoemulsification machines, each with different modes, but also to assess the relationship between postoperative endothelial cell loss and the phacoemulsification parameters, as well as the other factors in both ***:This prospective observational study was comprised of consecutive eligible cataract patients operated with phacoemulsification technique performed by the same surgeon using either a WHITESTAR Signature Ellips FX(transversal, group 1) or Infiniti OZil IP(torsional, group 2) ***:The study included 86 patients. Baseline characteristics in the groups were similar. The median nuclear sclerosis grade was 3(2-4) in the first group and2(2-4) in the second group(P =0.265). Both groups had similar phacoemulsification needle times(group 1: 60.63±36 s; group 2: 55.98±30 s; P =0.789). The percentage of endothelial cell loss 30 d after surgery ranged from 3% to15% with a median of 7% in group 1, and from 2% to13% with a median of 6% in group 2; however, there was no statistically significant difference between the groups(P =0.407). Hexagonality(P =0.794) and the coefficient of variation(CV; P =0.142) did not differ significantly between the groups before and 30 d after surgery. Asignificant positive correlation was found between the endothelial cell loss and nuclear sclerosis grade(group1: P <0.001; group 2: P <0.001) and between the endothelial cell loss and average phacoemulsification power(group 1: P =0.007; group 2: P =0.008).CONCLUSION:Both of these machines were efficient,with similar endothelial cell loss. This endothelial cell loss was related to the increased nuclear sclerosis grade and increased phacoemulsification power.

关键词： endothelial cell changes transversal torsional phacoemulsification

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Effects of moxifloxacin exposure on the conjunctival flora and antibiotic resistance profile following repeated intravitreal injections

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International Journal of Ophthalmology(English edition) 2014年第5期7卷 855-859页

作者： mustafa atas Burhan Baskan Ayse zkse Fatma Mutlu Sarιgüzel Süleyman Demircan Emine Pangal Department of Ophtalmology Kayseri Education and Research Hospital Department of Microbiology Kayseri Education and Research Hospital

AIMTo evaluate the effects of moxifloxacin exposure on the conjunctival flora and antibiotic resistance profile following repeated intravitreal injections.

关键词： intravitreal injection moxifloxacin endopthalmitis

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Evaluation of early results of quick-chop phacoemulsification in the patients with high myopic cataract

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International Journal of Ophthalmology(English edition) 2014年第5期7卷 828-831页

作者： Ali Akal Tugba Goncu Sevin Soker Cakmak Isa Yuvaci mustafa atas Süleyman Demircan Omer Faruk Yilmaz Department of Ophthalmology School of MedicineHarran University Department of Ophthalmology Kayseri Training and Research Hospital

AIM:To assess the early surgical outcomes of quickchop phacoemulsification technique in patients with high ***:The data of patients with high myopia who underwent quick-chop phacoemulsification were reviewed retrospectively. There were 42 eyes of 31 patients. The axial length was more than 26 mm in all eyes. All eyes underwent quick-chop phacoemulsification surgery with the placement of an intraocular lens(IOL) in the capsular bag. Postoperative visits were performed at 1, 3d; 2wk,1mo. Early postoperative best corrected visual acuity(BCVA), preoperative and postoperative corneal endothelial cell density(ECD), central corneal thickness(CCT) and postoperative complications were *** sample t-test or Wilcoxon tests were used to compare data between preoperative and postoperative data.· RESULTS:There was no statistically significant difference between preoperative and postoperative ECD and CCT. Retinal detachment was developed in one eye at postoperative first day. There was an iris prolapsus from side port insicion.· CONCLUSION:Quick-chop phacoemulsification technique is a safe surgical technique. However we can encounter some complications in high myopic eyes due to histopathological differences. Both side port and clear corneal tunnel insicion size is crucial for preventing postoperative complications. If any persistent leakage is noticed, suture should be placed.

关键词： high myopia cataract quick-chop phacoemulsification intraocular lens

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比较21G弯头和直头在横向劈核微切口同轴超声乳化手术中的应用(英文)

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国际眼科杂志 2015年第12期15卷 2029-2035页

作者： Süleyman Demircan mustafa atas Emre Goktas Burhan Baskan Gokmen Zararsiz 开塞利培训与研究医院眼科门诊土耳其开塞利38010 埃尔吉耶斯大学生物统计学系土耳其开塞利38010

目的:比较在微切口同轴扭动超声乳化使用直头和弯头的术中表现和术后结果。方法:白内障患者行2.2mm横向劈核微切口同轴超声乳化术中使用30°直头或弯头进行治疗。术中检查分析包括平均超声功率,总超声乳化时间,有效的超声乳化时间。使... 详细信息

目的:比较在微切口同轴扭动超声乳化使用直头和弯头的术中表现和术后结果。方法:白内障患者行2.2mm横向劈核微切口同轴超声乳化术中使用30°直头或弯头进行治疗。术中检查分析包括平均超声功率,总超声乳化时间,有效的超声乳化时间。使用非接触镜显微镜评估术前和术后1d,7d和30d的中央内皮细胞密度和角膜中央厚度。结果:此研究共纳入白内障患者190例190眼,95眼为弯头组,95眼为直头组。术中检查显示弯头组总超声乳化时间和有效的超声乳化时间较直头组显著降低(P<0.05)。弯头组总超声乳化时间和有效的超声乳化时间中位数分别为25.9(13.5-45.0)s(四分位间距)和18.0(9.0-30.0)s,直头组分别为38.8(16.5-73.5)s和26.0(11.0-49.0)s。结论:横向劈核微切口同轴超声乳化术中,相比较直头,使用弯头可以更加有效的摘除晶体,在所有阶段中除了第四阶段,总超声乳化时间和有效的超声乳化时间更短。

关键词：横向劈核微切口同轴超声乳化弯头直头微切口同轴超声乳化

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虹膜颜色与视网膜神经纤维层和黄斑及脉络膜厚度关系的研究（英文）

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国际眼科杂志 2017年第9期17卷 1610-1614页

作者： Süleyman Demircan Ugur Yilmaz Yudum Yüce Ahmet Gülhan Erkut Kücük mustafa atas 开塞利治疗研究医院眼科土耳其开塞利38010 尼代省医院眼科土耳其尼代51000

目的:明确眼虹膜颜色与眼轴长度、眼压、视网膜神经纤维层厚度(RNFL)、黄斑厚度、脉络膜厚度是否相关。方法:前瞻性横断面研究。92例(92眼)正常个体根据虹膜颜色分为深色组(DCE)和浅色组(LCE)。用标准光学相干断层扫描(OCT)分析RNFL和... 详细信息

目的:明确眼虹膜颜色与眼轴长度、眼压、视网膜神经纤维层厚度(RNFL)、黄斑厚度、脉络膜厚度是否相关。方法:前瞻性横断面研究。92例(92眼)正常个体根据虹膜颜色分为深色组(DCE)和浅色组(LCE)。用标准光学相干断层扫描(OCT)分析RNFL和黄斑厚度,EDI(Electronic data interchange)分析脉络膜厚度。脉络膜厚度在中央凹及水平位置距离中央凹1500μm的鼻侧、颞侧进行测量。结果:92眼中,深色组62眼(67.4%)平均年龄29.22±5.86y,浅色组30眼(32.6%)平均年龄28.86±6.50y。各组间平均年龄、眼轴长度、黄斑厚度、脉络膜厚度及眼压无显著性差异(P>0.05)。视网膜神经纤维层厚度的变化取决于测量象限,而LCE个体在全眼球,鼻侧和颞侧象限较低(P≤0.022)。结论:深色组和浅色组个体间眼内压(IOP),黄斑厚度和脉络膜厚度无显著差异。

关键词：视网膜神经纤维层厚度脉络膜厚度眼睛颜色虹膜颜色

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Pentacam Scheimpflug成像测量晶状体密度与torsional超声乳化参数间的关系（英文）

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国际眼科杂志 2014年第10期14卷 1739-1743页

作者： Suleyman Demircan mustafa atas Murat Koksal Emine Pangal Isa Yuvaci Altan Goktas 开赛里培训研究医院眼科土耳其开赛里138010 开赛里Modern Dunya医院土耳其开赛里238010

目的：评价运用Pentacam Scheimpflug成像测量晶状体核密度与torsinal超声乳化动力学参数（如：运用于老年核性白内障患者的超声能量水平、液体留存时间及液体量）间的关系。方法：此研究为前瞻性双盲研究。瞳孔扩大后运用Pentacam Sche... 详细信息

目的：评价运用Pentacam Scheimpflug成像测量晶状体核密度与torsinal超声乳化动力学参数（如：运用于老年核性白内障患者的超声能量水平、液体留存时间及液体量）间的关系。方法：此研究为前瞻性双盲研究。瞳孔扩大后运用Pentacam Scheimpflug 成像进行测量。白内障的等级由pentacam核密度测定法[ pentacam nucleus densitometry, PND；又名Pentacam核分段（ Pentacam nucleus staging, PNS）软件]自主分为1到5个等级。超声乳化术后,自动在Infiniti Ozil IP超声乳化系统监视器上计算并显示总超声（ U/S）时间、累计耗散能、Torsional U/S时间以及估算液体的使用情况。组间差异运用单因素方差分析（ ANOVA ）进行评定,多组分析运用Tamhane测试法,PND测量的晶状体密度与torsinal超声乳化动力学参数间的关系运用Spearman相关分析进行评定。界定P〈0.05时具有统计学意义。结果：此项研究包括125例患者（125眼）,平均年龄为69.7±9.4岁（范围：48~88岁）,其中61例男性、64例女性。 U/S总时间、torsional U/S时间、CDE及估算液体使用情况的范围分别为0.70~158.9s,0.70~158.5s,0.11~42.65和21~98mL. PND组间数据有统计学差异。评估超声乳化动力学参数与PND数据间关系后得出PND数据与总超声时间（ r=0.767； P〈0.01）、torsional超声时间（r=0.767；P〈0.01）、CDE（r=0.758； P〈0.01）及液体使用量（r=0.602；P〈0.01）均有显著相关性。结论：白内障手术前运用PND评分法获得核密度的客观程度可为超声乳化术中的参数提供可靠的预见性。因此,对每一位患者进行每一单项超声乳化参数的评估,有助于降低超声乳化能量的使用量,减少内皮细胞丢失和类固醇的使用,加速视力的恢复。

关键词： torsional超声乳化 pentacam 沙氏成像晶状体密度测定

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单剂量0.15%酒石酸溴莫尼定对正常个体脉络膜厚度的影响（英文）

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国际眼科杂志 2017年第11期17卷 2000-2004页

作者： Suleyman Demircan Gokcen Gokce mustafa atas Ahmet Gulhan Burhan Baskan Gokmen Zararsiz 开塞利医疗研究医院眼科土耳其开塞利38010 开塞利军事医院眼科土耳其开塞利38010 埃尔吉耶斯大学生物统计学系土耳其开塞利38010

目的:通过使用频域相干光学断层深度增强成像测量正常个体脉络膜厚度(CT)以评估眼部使用0.15%酒石酸溴莫尼定对眼后节的潜在影响。方法:前瞻性、安慰剂对照干预性临床试验,包括32例32眼正常个体。第1d,受试者接受一滴无防腐剂人工泪液... 详细信息

目的:通过使用频域相干光学断层深度增强成像测量正常个体脉络膜厚度(CT)以评估眼部使用0.15%酒石酸溴莫尼定对眼后节的潜在影响。方法:前瞻性、安慰剂对照干预性临床试验,包括32例32眼正常个体。第1d,受试者接受一滴无防腐剂人工泪液作为安慰剂;第2d,接受一滴0.15%酒石酸溴莫尼定。收集每次用药前及用药后1、3和5h,眼压,眼灌注压(OPP)以及EDI-SD-OCT数据。结果:相较于最初测量结果,局部应用0.15%酒石酸溴莫尼定后,在下凹(P=0.001),颞凹1500μm处(P=0.003),鼻凹1500μm处(P=0.003)测得脉络膜厚度显著增加。整个研究过程中,安慰剂组脉络膜厚度未发生变化(P>0.05)。分别使用安慰剂和溴莫尼定后眼灌注压没有显著降低(P>0.05)。研究中未观察到不良反应。结论:与预期相悖,局部应用0.15%酒石酸溴莫尼定导致下凹、颞凹、鼻凹处脉络膜厚度增加。

关键词：溴莫尼定脉络膜厚度增强深度成像眼压光学相干断层扫描

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