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Accurate positioning of the 24-hour pH monitoring catheter:Agreement between manometry and pH step-up method in two patient positions

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World Journal of Gastroenterology 2007年第46期13卷 6197-6202页

作者： Mehmet Fatih Can Gokhan Yagci Sadettin Cetiner mustafa Gulsen Taner Yigit erkan Ozturk Semih Gorgulu Turgut Tufan Departments of General Surgery Gulhane Military Medical AcademyEtlikAnkaraTurkey "Reflux Research Group"Gulhane Military Medical AcademyEtlikAnkaraTurkey Gastoenterology and Hepatology Gulhane Military Medical AcademyEtlikAnkaraTurkey "Reflux Research Group"Gulhane Military Medical AcademyEtlikAnkaraTurkey Departments of General Surgery Gulhane Military Medical AcademyEtlikAnkaraTurkey

AIM： TO investigate the agreement between esophageal manometry and pH step-up method in two different patient positions. METHODS： Eighteen subjects were included in the study. First, the distance from the nose to the proximal border of the lower esophageal sphincter （LES） was measured manometrically. Then a different investigator, who was blinded to the results of the first study, measured the same distance using the pH step-up method, with the patient in both upright and supine positions. An assessment of agreement between the two techniques was performed. RESULTS： In the supine position, the measurement of only one subject was outside the range accepted for correct positioning （~〈 3 cm distal or proximal to the LES）. In the upright position, errors in measurement were recognized in five subjects. Bland-Airman plots revealed good agreement between measurements obtained manometrically and by the pH-step up method with the patient in the supine position. CONCLUSION： In the case of nonavailability of manometric detection device, the pH step-up method can facilitate the positioning of the 24 h pH monitoring catheter with the patient in the supine position. Thisshould increase the use of pH-metry in clinical practice for subjects with suspected gastroesophageal reflux disease if our results are supported by further studies.

关键词： pH monitoring Esophageal manometry pHstep-up method Gastroesophageal reflux

Multivariate statistical methods and GIS based evaluation of the health risk potential and water quality due to arsenic pollution in the K?z?l?rmak River

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International Journal of Sediment Research 2022年第6期37卷 754-765页

作者： Hüseyin Cüce erkan Kal?pc? Fikret Ustao?lu Ilknur Kaynar Volkan Baser mustafa Türkmen Deparment of Geomatics Engineering Giresun University Department of Biology Giresun University Deparment of Environmental Engineering Nevsehir Hac? Bektas Veli University

The K?z?l?rmak River is Turkey?s longest(1,355 km) river and it is important since it constitutes the drinking and irrigation water source of the Central Anatolia Region. In the current study, the spatial distribution, effect on irrigation water quality, environmental pollution status, ecotoxicological and health risks as well as possible sources of 12 potential toxic elements?(PTEs)(manganese(Mn),aluminum(Al), arsenic(As), chromium(Cr), zinc(Zn), iron(Fe), nickel(Ni), cadmium(Cd), cobalt(Co),copper(Cu), mercury(Hg), and lead(Pb)) concentrations from surface water samples in the K?z?l?rmak River were analyzed by using geographical information systems(GIS) software, ecotoxicological indices,and multivariate statistical analysis. As a result of the current study, it was determined that the As concentration is above the World Health Organization(WHO) limit values, and, in terms of the 12 PTEs,there is slight heavy metal contamination in the river according to the Heavy Metal Pollution Index(HPI)and Heavy Metal Evaluation Index(HEI) values and there is a low level of pollution. The Hazard Quotient for ingestion(HQingestion) and Hazard Index(HI) values indicate that non-carcinogenic effects may *** to river water is likely to result in a low level of carcinogenic risk(CR) in adults, mainly due to the As concentration. The water at Sampling Station S3(131.79) cannot be used for drinking and is not suitable for consumption. According to the sodium percentage(Na%), Sodium Absorption Ratio(SAR),and Magnesium Hazard(MH) index results, river water is suitable for agricultural use.

关键词： Kızılırmak Water quality indexes Public health Arsenic pollution Multivariate statistical methods

A Root Canal Therapy on the Maxillary First Molar Tooth with Five Canals: A Case Report

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Open Journal of Stomatology 2015年第4期5卷 102-107页

作者： erkan Erhan Gundogar mustafa Department of Enodontic Faculty of Dentistry Istanbul Medipol University Bagcilar Istanbul

Maxillary first molar usually exhibits a radicular anatomy of three roots and three or four canals. However, different anatomic variations like extra number of roots and canals are possible. For a successful treatment, clinicians must have well equipment and a thorough knowledge of the external and internal anatomy of teeth and its variation. Using of CBCT may help to locate extra canals by giving a chance to clinicians to see the root canal anatomy in 3-D view. The aim of this study was to present a case report about a diagnosis and treatment in maxillary first molar with three roots and five canals. It is concluded that the diagnosing and the treatment of unusual cases are key factors for successful endodontic treatment of these teeth.

关键词： Root Canal Therapy Maxillary First Molar Anatomy

Effect of transcatheter aortic valve implantation on QT dispersion in patients with aortic stenosis

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Journal of Geriatric Cardiology 2014年第4期11卷 286-290页

作者： Hakan erkan Engin Hatem mustafa Tank Agac Levent Korkmaz Teyyar Gokdeniz Ahmet Cagrl Aykan Ezgi Kalaycloglu Faruk Boyacl Omer Faruk Clrakoglu Sukru Celik Department of Cardiology Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital Camhk Street Trabzon 61040 Turkey Department of Cardiology Kafkas University Hospital Kars Turkey

Background QT dispersion （QTd） is a predictor of ventricular arrhythmia. Ventricular arrhythmia is an important factor influencing morbidity and mortality in patients with aortic stenosis. Surgical aortic valve replacement reduced the QTd in this patients group. However, the effect of transcatheter aortic valve implantation （TAVI） on QTd in patients with aortic stenosis is unknown. The aim of this study was to investigate the effect of TAVI on QTd in patients with aortic stenosis. Methods Patients with severe aortic stenosis, who were not candi-dates for surgical aortic valve replacement due to contraindications or high surgical risk, were included in the study. All patients underwent electrocardiographic and echocardiographic evaluation before, and at the 6th month after TAVI, computed QTd and left ventricular mass index （LVMI）. Results A total 30 patients were admitted to the study （mean age 83.2 ± 1.0 years, female 21 and male 9, mean valve area 0.7 ± 3 mm2）. Edwards SAPIEN heart valves, 23 mm （21 patients） and 26 mm （9 patients）, by the transfemoral approach were used in the TAVI procedures. All TAVI procedures were successful. Both QTd and LVMI at the 6th month after TAVI were significantly reduced com-pared with baseline values of QTd and LVMI before TAVI （73.8 ± 4 ms vs. 68 ± 2 ms, P=0.001 and 198 ± 51 g/m2 vs. 184 ± 40 g/m2, P=0.04, respectively）. There was a significant correlation between QTd and LVMI （r=0.646, P〈0.001）. Conclusions QTd, which malign ventricular arrhythmia marker, and LVMI were significantly reduced after TAVI procedure. TAVI may decrease the possibility of ventricu-lar arrhythmia in patients with aortic stenosis.

关键词： Aortic stenosis QT dispersion Transcatheter aortic valve implantation

The Relationship between Dental Indentation and Maxillary Sinusitis

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Open Journal of Medical Imaging 2013年第2期3卷 65-68页

作者： Duzgun Yildirim Murat Eroglu Murat Salihoglu Ali Osman Yildirim Huseyin Karagoz mustafa erkan Centermed Advanced Imaging Center Department of Radiology Istanbul Turkey Gulhane Military Medical Academy Haydarpasa Training Hospital Department of Ear Nose Throat Istanbul Turkey Gulhane Military Medical Academy Haydarpasa Training Hospital Department of Emergency Medicine Istanbul Turkey Gulhane Military Medical Academy Haydarpasa Training Hospital Department of Orthodontics Istanbul Turkey Gulhane Military Medical Academy Haydarpasa Training Hospital Department of Plastic Surgery Istanbul Turkey

Purpose: To determine the relationship between the dental root indentation and maxillary sinusitis. Methods: We assessed the records of the patients who underwent paranasal sinus computed tomography imaging for suspected sinusitis. Results: We identified a total of 52 patients with a pre-diagnosis of maxillary sinusitis. Dental indentation was detected in 58 of 104 (55.7%) sinuses. Forty six of 58 sinuses (79.3%) with dental indentation had mucosal thickening higher than 2 mm. The difference between the groups was statistically significant (p = 0.007). Conclusion: Dental indentation should be kept in mind as a reason for chronic maxillary sinus inflammation, if an underlying cause cannot be identified.

关键词： Maxillary Sinus Dental Indentation Mucosal Thickening Computerized Tomography

Isolated dorsal approach for the treatment of neglected volar metacarpophalangeal joint dislocations

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世界骨科杂志：英文版 2014年第1期5卷 62-66页

作者： Hakan Ba?ar mustafa erkan ?nanmaz Kamil ?a?r? K?se Cihangir Tetik Department of Orthopaedic and Traumatology Sakarya Training and Research Hospital Department of Orthopaedics and Traumatology Acibadem Maslak Hospital

Here, we present the clinical and radiological results of three neglected volar metacarpophalangeal dislocations in 2 patients, which were treated with open reductions 10 and 24 mo after the dislocations. There was a mean of a 20°(range 10°-30°) limitation of extension and a 53.3°(range 30°-70°) limitation of flexion preoperatively. Postoperatively, there was no limitation of extension(at 8 and 12 mo) in any of the fingers. In terms of flexion, one finger had full function, one had a 10° and the last one had a 30° limitation of flexion. Two of the fingers presented anesthesia preoperatively, which improved to hypesthesia postoperatively. One finger had hypesthesia, which improved postoperatively. During surgery, a ruptured dorsal capsule was found to have interposed into the joint, making closed reduction impossible. Our experience with these two patients demonstrated that, even in neglected cases, open reduction using an isolated dorsal approach may result in satisfactory clinical andradiological outcomes.

关键词： metacarpophalangeal dislocation Neglected dislocation Surgical treatment Dorsal surgical approach metacarpophalangeal dislocation rehabilitation

Impact of adjuvant treatment modalities on survival outcomes in curatively resected pancreatic and periampullary adenocarcinoma

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Chinese Journal of Cancer Research 2015年第4期27卷 408-416页

作者： Nedim Turan mustafa Benekli Olcun Umit Unal ?lkay Tugba Unek Didem Tastekin Faysal Dane Efnan Alg?n Sukran Ulger Tulay Eren Turkan Ozturk Topcu Esma Turkmen Nalan Akgül Babacan Gulnihal Tufan Zuhat Urakci Basak Oven Ustaalioglu Ozlem Sonmez Uysal Ozlem Balvan Ercelep Burcu Yapar Taskoylu Asude Aksoy mustafa Canhoroz Umut Demirci erkan Dogan Veli Berk Ozan Balakan Ahmet ?iyar Ekinci Mukremin Uysal ?brahim Petekkaya Sel?uk Cemil Ozturk ?nder Tonyal? Bülent ?etin Mehmet Naci Aldemir Kaan Helvac? Nuriye Ozdemir ?lhan Oztop Ugur Coskun Aytug Uner Ahmet Ozet Suleyman Buyukberber Department of Medical Oncology Faculty of Medicine Cumhuriyet University Department of Medical Oncology Faculty of Medicine Gazi University Department of Medical Oncology Faculty of Medicine Dokuz Eylul University Department of Medical Oncology Faculty of Medicine Necmettin Erbakan University Department of Medical Oncology Faculty of Medicine Marmara University Department of Radiation Oncology Faculty of Medicine Gazi University Department of Medical Oncology Numune Education and Research Hospital Department of Medical Oncology Faculty of Medicine Karadeniz Technical University Department of Medical Oncology Faculty of Medicine Trakya University Department of Medical Oncology Rize Education and Research Hospital Department of Medical Oncology Faculty of Medicine Dicle University Department of Medical Oncology Dr.Lutfi Kirdar Kartal Education and Research Hospital Department of Medical Oncology Sakarya Education and Research Hospital Department of Medical Oncology Faculty of Medicine Pamukkale University Department of Medical Oncology Faculty of Medicine Inonu University Department of Medical Oncology Faculty of Medicine Firat University Department of Medical Oncology Dr.Abdurrahman Yurtaslan Education and Research Hospital Department of Medical Oncology Faculty of Medicine Yuzuncu Yil University Department of Medical Oncology Faculty of Medicine Erciyes University Department of Medical Oncology Faculty of Medicine Sutcu Imam University Department of Medical Oncology Diyarbakir Education and Research Hospital Department of Medical Oncology Faculty of Medicine Kocatepe University Department of Medical Oncology Dr.Ersin Arslan State Hospital Department of Medical Oncology Education and Research Hospital Ad?yaman University Department of Medical Oncology Faculty of Medicine Mustafa Kemal University Department of Medical Oncology Faculty of Medicine Ataturk University

Background： We examined the impact of adjuvant modalities on resected pancreatic and periampullary adenocarcinoma（PAC）.Methods： A total of 563 patients who were curatively resected for PAC were retrospectively analyzed between 2003 and ***： Of 563 patients, 472 received adjuvant chemotherapy（CT） alone, chemoradiotherapy（CRT） alone, and chemoradiotherapy plus chemotherapy（CRT-CT） were analyzed. Of the 472 patients, 231 were given CRT-CT, 26 were given CRT, and 215 were given CT. The median recurrence-free survival（RFS） and overall survival（OS） were 12 and 19 months, respectively. When CT and CRT-CT groups were compared, there was no significant difference with respect to both RFS and OS, and also there was no difference in RFS and OS among CRT-CT, CT and CRT groups. To further investigate the impact of radiation on subgroups, patients were stratified according to lymph node status and resection margins. In node-positive patients, both RFS and OS were significantly longer in CRT-CT than CT. In contrast, there was no significant differencebetween groups when patients with node-negative disease or patients with or without positive surgical margins were ***： Addition of radiation to CT has a survival benefit in patients with node-positive disease following pancreatic resection.

关键词： Pancreatic adenocarcinoma adjuvant chemotherapy(adjuvant CT) adjuvant radiotherapy