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Competitive Project Scheduling on Two Unbounded Parallel Batch Machines

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Journal of the Operations Research Society of China 2018年第3期6卷 349-389页

作者： Ling-fa Lu Li-Qi Zhang School of Mathematics and Statistics Zhengzhou UniversityZhengzhou 450001China College of Information and Management Science Henan Agricultural UniversityZhengzhou 450003China

This paper considers competitive project scheduling on two unbounded parallel batch *** are two competing firms,and each firm has an unbounded parallel batch *** projects must be performed in batches by Firms 1 and 2 on their machines,*** profit that each firm obtains from each project depends on whether the firm finishes the job before or after its *** the first problem,given a feasible schedule for Firm 1,the objective is to find an optimal schedule to maximize the total reward for Firm 2 under the given schedule for Firm *** corresponding total reward for Firm 1 is called the worst-case total reward of the given schedule for Firm *** the second problem,the objective is to find an optimal schedule for Firm 1 to maximize the worst-case total *** provide optimal algorithms for the two problems,respectively.

关键词： Project scheduling Competition Parallel batch machine

Progress in Chemical Synthesis of Peptides and Proteins

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Transactions of Tianjin University 2017年第5期23卷 401-419页

作者： Wen Hou Xiaohong Zhang Chuan-fa Liu School of Life Sciences Tianjin University School of Biological Sciences Nanyang Technological University

For the proteins that cannot be expressed exactly by cell expression technology (e.g., proteins with multiple posttranslational modifications or toxic proteins), chemical synthesis is an important substitute. Given the limited peptide length offered by solid-phase peptide synthesis invented by Professor Merrifield, peptide ligation plays a key role in long peptide or protein synthesis by ligating two small peptides to a long one. Moreover, high-molecular-weight proteins must be synthesized using two or more peptide ligation steps, and sequential peptide ligation is such an efficient way. In this paper, we reviewed the development of chemical protein synthesis, including solid-phase peptide synthesis, chemical ligation, and sequential chemical ligation. © 2017, The Author(s).

关键词： Chemical modification Peptides Proteins Surgical equipment Synthesis (chemical)

Automatic data archiving and visualization at HLS-Ⅱ

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Nuclear Science and Techniques 2018年第9期29卷 179-184页

作者： Yi-fan Song Chuan Li Ke Xuan Gong-fa Liu National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029China

The control system of Hefei Light Source II(HLS-Ⅱ) is a distributed system based on the experimental physics and industrial control system(EPICS). It is necessary to maintain the central configuration files for the existing archiving system. When the process variables in the control system are added, removed, or updated, the configuration files must be manually modified to maintain consistency with the control system. This paper presents a new method for data archiving, which realizes the automatic configuration of the archiving parameters. The system uses microservice architecture to integrate the EPICS Archiver Appliance and Rec Sync. In this way, the system can collect all the archived meta-configuration from the distributed input/output controllers and enter them into the EPICS Archiver Appliance automatically. Furthermore, we also developed a web-based GUI to provide automatic visualization of real-time and historical data. At present,this system is under commissioning at HLS-Ⅱ. The results indicate that the new archiving system is reliable and convenient to operate. The operation mode without maintenance is valuable for large-scale scientific facilities.

关键词： Automatic archiving Data visualization Microservice architecture EPICS Archiver Appliance

Tier-1 assays for assessing the toxicity of insecticidal proteins produced by genetically engineered plants to non-target arthropods

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Insect Science 2014年第2期21卷 125-134页

作者： Yun-He Li Jorg Romeis Kong-Ming Wu Yu-fa Peng State Key Laboratory for Plant Diseases and Insect Pests Institute of Plant Protection Chinese Academy of Agricultural Sciences Beijing China Agroscope Reckenholz-Tanikon Research Station ART Zurich Switzerland

In assessing an insect-resistant genetically engineered （IRGE） crop before its commercialization, researchers normally use so-called ＂Tier-1 assays＂ as the initial step to determine the effects of the crop on non-target organisms. In these tests, the insecticidal proteins （IPs） produced by the IRGEs are added to the diets of test organisms in the laboratory. Test organisms in such assays can be directly exposed to much higher concentrations of the test IPs than they would encounter in the field. The results of Tier-1 assays are thus more conservative than those generated in studies in which the organisms are exposed to the IPs by feeding on IRGE plant tissue or in the case of predators or parasites, by feeding on invertebrate prey or hosts that have fed on IRGE plant tissue. In this report, we consider three important factors that must be considered in Tier-1 assays：（i） methods for delivery of the IP to the test organisms; （ii） the need for and selection of compounds used as positive controls; and （iii） methods for monitoring the concentration, stability and bioactivity of the IP during the assay. We also analyze the existing data from Tier-1 assays regarding the toxicity of Bt Cry proteins to non-target arthropod species. The data indicate that the widely used Bt proteins have no direct toxicity to non-target organisms

关键词： artificial diet Cry protein environmental risk assessment ELISA positivecontroll sensitive insect bioassay

Development of Glass Ceramics Made From Ferrous Tailings and Slag in China

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Journal of Iron and Steel Research International 2007年第2期14卷 73-78页

作者： LIU Cheng-jun SHI Pei-yang ZHANG Da-yong JIANG Mao-fa School of Materials and Metallurgy Northeastern University Shenyang 110004 Liaoning China

A great amount of ferrous tailings and slag cause severe damage to the ecological environment, which must be reclaimed and utilized. The composition, type, and characteristics of ferrous tailings and slag in China were introduced. The research status and the application outlook of glass ceramics made from ferrous tailings and slag were discussed. Glass ceramics made from ferrous tailings and slag can be applied to various fields, and it will be environmentally conscious materials in the 21st century.

关键词： glass ceramics ferrous tailings slag

A local-optimization refinement algorithm in single particle analysis for macromolecular complex with multiple rigid modules

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Protein & Cell 2016年第1期7卷 46-62页

作者： Hong Shan Zihao wang fa Zhang Yong Xiong Chang-Cheng Yin Fei Sun Department of Biophysics College of Basic Medical Sciences Peking University Health Science Center Beijing 100191China National Laboratory of Biomacromolecules Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China Key Lab of Intelligent Information Processing and Advanced Computing Research Lab Institute of Computing TechnologyChinese Academy of Sciences Beijing 100190 China University of Chinese Academy of Sciences Beijing 100049 China Department of Molecular Biophysics and Biochemistry Yale University New Haven CT 06511 USA Center for Biological Imaging Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China

Single particle analysis, which can be regarded as an average of signals from thousands or even millions of particle projections, is an efficient method to study the three-dimensional structures of biological macro- molecules. An intrinsic assumption in single particle analysis is that all the analyzed particles must have identical composition and conformation. Thus specimen heterogeneity in either composition or conformation has raised great challenges for high-resolution analysis. For particles with multiple conformations, inaccurate align- ments and orientation parameters will yield an averaged map with diminished resolution and smeared density. Besides extensive classification approaches, here based on the assumption that the macromolecular complex is made up of multiple rigid modules whose relative orien- tations and positions are in slight fluctuation around equilibriums, we propose a new method called as local optimization refinement to address this conformational heterogeneity for an improved resolution. The key idea is to optimize the orientation and shift parameters of each rigid module and then reconstruct their three-dimen- sional structures individually. Using simulated data of 80S/70S ribosomes with relative fluctuations between the large （60S/50S） and the small （40S/30S） subunits, we tested this algorithm and found that the resolutions of both subunits are significantly improved. Our method provides a proof-of-principle solution for high-resolutionsingle particle analysis of macromolecular complexes with dynamic conformations.

关键词： cryo-electron microscopy single particleanalysis conformational heterogeneity rigid module Iocaoptimization refinement

Isolated Main Galaxy Pairs from the SDSS Data Release 4

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Chinese Journal of Astronomy and Astrophysics 2006年第4期6卷 411-420页

作者： Xin-fa Deng Yi-Qing Chen Ping Wu Cheng-Hong Luo Ji-Zhou He Mathematics and Physics College Nanchang University Nanchang 330047 Management College Nanchang UniversityNanchang330047

From the Main galaxy data of the SDSS Data Release 4 （SDSS4）, we have identiffed close galaxy pairs at neighbourhood radius R = 100 kpc by three-dimensional cluster analysis. Using the criterion that an ＂isolated galaxy pair＂ must be separated from its ＂nearest neighbor＂ by more than 500 kpc, we constructed an isolated galaxy pair sample of 1158 pairs. We also constructed a random pair sample by randomly selecting 1158 galaxy pairs from the Main galaxy sample, which has the same redshift distribution as the isolated galaxy pair sample, and in which the two components of any pair have the same redshifts. Comparative studies of luminosity and size between the members of the galaxy pairs are performed. We find and further confirm there is no tendency for paired galaxies to have similar luminosities or sizes. From the isolated pair sample we also selected a subsample with the magnitude limit of the primary raised by 2 magnitudes, so as to include pairs in which the secondary is 2 magnitudes fainter than the primary. This subsample contains 82 pairs. A random pair sample is similarly constructed.

关键词： galaxy: fundamental parameters- galaxies: interactions

Effects of electric-acoustic and acoustic-electric conversions of transducers on acoustic logging signal

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Chinese Science Bulletin 2012年第11期57卷 1246-1260页

作者： fa Lin XIE WenYan TIAN Yong ZHAO MeiShan MA Li DONG DaQun School of Electronics Engineering Xi'an University of Post and TelecommunicationsXi'an 710121China PetroChina Liaohe Oilfield Company Panjin 124013China The James Franck Institute and Department of Chemistry The University of ChicagoChicagoIL 60637USA Department of Digital Media andArt Xi'an University of Post and TelecommunicationsXi'an 710121China School of Marine Engineering Northwest Polytechnical UniversityXi'an 710071China

Based on an acoustic logging transmission network and the engineering pattern of a sliding wave in acoustic logging, analysis and calculations have been performed in a study of the effects of the electric-acoustic and acoustic-electric conversions of the transducers on the acoustic logging signal. The results show that acoustic-electric conversion through the transducer can cause not only a serious disturbance in the signal amplitude, but also an apparent transmission delay. For engineering applications, the amplitude variation and transmission delay must be accounted for in a practical analysis of the acoustic logging signal in rocks. The results also show that with enhanced understanding and proper justification, the error caused by the acoustic-electric conversion can be significantly reduced in evaluation of the cement bond quality of a cased well, and the accuracy of rock porosity calculated using the measured acoustic velocity can be increased.

关键词：声波测井测井信号换能器电声声电转换传输网络信号幅度传输延迟

Effect of Peak Power and Pulse Width on Coherent Doppler Wind Lidar’s SNR

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Instrumentation 2022年第2期9卷 26-32页

作者： REN Yong WU Xuefei TAO fa CAO Haishuai Fujian Key Laboratory of Severe Weather Fuzhou 350001 Meteorological Observation Center of the China Meteorological Administration Beijing 100081 Fujian Atmospheric Detection Technology Support Center Fuzhou 350008 Qingdao Leice Transient Technology Co.Ltd Qingdao 266000

The laser device is the core component of coherent Doppler wind *** peak power and pulse width of laser transmitting pulse have important effects on *** on coherent Doppler wind pulse lidar,the peak power and pulse width influence on SNR is studied on the theoretical derivation and analysis,and the results show that the higher the peak power can realize the greater the signal-to-noise ratio of coherent Doppler wind *** when the peak power is too large,the laser pulse may appear nonlinear phenomenon,which cause the damage of the ***,the peak power must be less than the stimulated brillouin scattering power *** the pulse width can make the laser device to output more energy,but it will also make the spatial resolution lower,and the influence of turbulence on SNR will be *** a series of simulation analyses,it can be concluded that when the peak power is 650W and the pulse width is 340ns,the SNR of the system can be *** addition,the coherent Doppler wind lidar system is set up to carry out corresponding experimental *** experimental results are consistent with the theoretical analysis and simulation,which verifies the correctness of the theoretical analysis and simulation *** provides theoretical basis and practical ex-perience for the design of laser transmitting pulse in coherent Doppler wind lidar system.

关键词： Coherent Lidar Fiber Laser Peak Power Pulse Width Signal-to-Noise Ratio(SNR)