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World Journal of Gastroenterology 2010年第39期16卷 4892-4904页

作者： Udayakumar Navaneethan Preethi gk Venkatesh Bo Shen Victor W.Fazio Center for Inflammatory Bowel Disease Department of GastroenterologyDigestive Disease Institutethe Cleveland Clinic Foundation

Clostridium difficile(***)infection(CDI)is the leading identifiable cause of antibiotic-associated *** there is an alarming trend of increasing incidence and severity of CDI in the United States and Europe,superimposed CDI in patients with inflammatory bowel disease(IBD)has drawn considerable attention in the gastrointestinal *** majority of IBD patients appear to contract CDI as *** affects disease course of IBD in several ways,including triggering disease flares,sustaining activity,and in some cases,acting as an"innocent"*** its wide spectrum of presentations,CDI has been reported to be associated with a longer duration of hospitalization and a higher mortality in IBD *** patients with restorative proctocolectomy or with diverting ileostomy are not immune to CDI of the small bowel or ileal *** immunomodulator or corticosteroid therapy for IBD should be continued in patients with superimposed CDI is *** appears that more adverse outcomes was observed among patients treated by a combination of immunomodulators and antibiotics than those treated by antibiotics *** use of biologic agents does not appear to increase the risk of acquisition of *** CDI in the setting of underlying IBD,vancomycin appears to be more efficacious than *** controlled trials are required to clearly define the appropriate management for CDI in patients with IBD.

关键词： Clostridium difficile Inflammatory bowel disease Antibiotics Colectomy

Electrochemical Studies on the Deposition of Neodymium in DMSO

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Chinese Chemical Letters 1998年第2期9卷 169-171页

作者： Liu, gk Gu, LW Tong, YX Liu, JP Lu, SJ Zhongshan Univ Sch Chem & Chem Engn Guangzhou 510275 Peoples R China

The electrodeposition of neodymium on Pt and Cu electrodes was investigated in DMSO containing NdCl3 and a small mount of water at room temperature. Cyclic voltammetry indicated that the reduction process of Nd(III) on the Pt cathode was complicated. The one-step reduction wave showed two steps by adding 0.3 mol/L ethylenediamine(EN). A delicate yellow, lustrous, strongly adhering film on the Cu electrode was obtained using potentiostatic electrolysis at -1.80 V (vs. aq SCE).

关键词： electrochemical studies deposition neodymium

Primary sclerosing cholangitis and the risk of colon neoplasia in patients with Crohn’s colitis

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Gastroenterology Report 2016年第3期4卷 226-231,I0002页

作者： Udayakumar Navaneethan Tarun Rai Preethi gk Venkatesh Ravi P Kiran Department of Gastroenterology Digestive disease InstituteThe Cleveland ClinicClevelandOHUSA Department of Colorectal Surgery Digestive disease InstituteThe Cleveland ClinicClevelandOHUSA

Background and aim:Crohn’s colitis(CC)is associated with primary sclerosing cholangitis(PSC).However the risk of colon cancer or dysplasia in CC and PSC is *** aim was to study the risk of colon neoplasia in CC in patients with and without ***:This is a nested,case-control cohort study of all patients diagnosed with concurrent CC and PSC,seen at the Cleveland Clinic between 1985 and ***-three patients with both CC and PSC were compared with a random sample of 159 CC controls without PSC during the same ***:Seven(16.3%)of 43 CC patients with PSC developed colon cancer or dysplasia,compared with 22(13.8%)of 159 controls(P=0.98).Of seven colon neoplasia cases in the PSC group,100%occurred proximal to the splenic flexure,compared with 50%(11/22)cases of colon neoplasia in controls occurring in the proximal colon(P=0.001).Based on Cox regression analysis,male gender independently increased the risk of neoplasia[hazard ratio(HR)=2.68;95%confidence interval(CI)1.30-5.54;P=0.008],as did age at CC diagnosis(HR=1.29;95%CI 1.14-1.47;P<0.001),while the use of azathioprine/6-mercaptopurine was protective(HR=0.30;95%CI 0.13-0.70;P=0.005).The presence of PSC did not increase the risk for colon neoplasia(HR=0.45;95%CI 0.18-1.13;P=0.09).Conclusions:CC patients with PSC appear not to be at increased risk of developing colon *** patients in our cohort with colon neoplasia and concurrent PSC,the neoplasia occurred in the proximal colon in all cases.

关键词： Crohn’s colitis primary sclerosing cholangitis colon neoplasia

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中国有色金属学会会刊：英文版 2001年第6期11卷 942-945页

作者： Yuang, DS Huang, KS Liu, gk Tong, YX Sa, LC Zhongshan Univ Sch Chem & Chem Engn Guangzhou 510275 Peoples R China

Potentiostatic and pulse electrolysis techniques were used to prepare La-Co-Fe alloy films using ethylenediamine (EN) as complexant. Surfaces of alloy films obtained by these two techniques are smooth, adhesive, compact and metallic luster. The contents of La in alloy films obtained by potentiostatic electrolysis technique are in the range of 13.23%～47.67%. The contents of La in alloy films deposited by pulse electrolysis technique are in the range of 10.67%～16.29%.

关键词： ethylenediamine lanthanum codeposition dimethylsulfoxide La-Co-Fe alloy films

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gk设计集团发展史(上)

设计 2011年第8期24卷 56-67页

作者： BK gk Group（图） BK gk Group

gk设计集团于1952年创立，起初专着工业设计业务，现今涵盖广泛的专业服务，包括了建筑与环境设计、平面设计及互动设计等领域。gk集团以其卓越的理论研究、发展规划、资料蔸集等服务而备受耩誉。gk设计集团包括了作为主纲的gk设计集团... 详细信息

gk设计集团于1952年创立，起初专着工业设计业务，现今涵盖广泛的专业服务，包括了建筑与环境设计、平面设计及互动设计等领域。gk集团以其卓越的理论研究、发展规划、资料蔸集等服务而备受耩誉。gk设计集团包括了作为主纲的gk设计集团公司，统共由七所本地公司及四所海外公司所组成，具国际性视野的作品遍布日常生活事物。

关键词：工业设计发展史专业服务环境设计互动设计平面设计集团公司国际性

Comparison of outcomes for patients with primary sclerosing cholangitis associated with ulcerative colitis and Crohn’s disease

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Gastroenterology Report 2016年第1期4卷 43-49,I0002页

作者： Udayakumar Navaneethan Preethi gk Venkatesh Ramprasad Jegadeesan Vennisvasanth Lourdusamy Jeffrey P Hammel Ravi P Kiran Bo Shen Department of Gastroenterology Digestive Disease InstituteThe Cleveland ClinicClevelandOHUSA Department of Colorectal Surgery Columbia University Medical CenterNew York Presbyterian HospitalNew YorkNYUSA.

Background:The comparative outcomes of ulcerative colitis(UC)and Crohn’s disease(CD)in patients with primary sclerosing cholangitis(PSC)are unclear;the aim of our study was to make an objective ***:A total of 273 patients with PSC and inflammatory bowel disease(223 with UC and 50 with CD)were *** and demographic variables were ***:The PSC risk score was similar for both *** median follow-up period in patients with PSC-UC was 12 years(range 0–38)and that for PSC-CD was 14 years(range 1–36).The median number of disease flares per year was higher in PSC-UC patients than in the PSC-CD group[1vs.0(ranges 0–20 and 0–9,respectively);P<0.001].More patients with UC developed colon neoplasia than CD(35.9%vs.18%;P=0.009).On proportional hazards analysis for the risk of colectomy,UC patients had a 12%higher risk for colectomy[hazard ratio(HR)=0.88;95%confidence interval(CI)0.51–1.51;P=0.64].Liver transplantation for PSC was associated with decreased risk(HR=0.57;95%CI 0.37–0.89;P=0.013),while colon neoplasia increased the risk(HR=3.83;95%CI 2.63–5.58;P<0.001)for *** proportional hazards analysis for the risk of colon neoplasia,UC patients had 56%higher risk of developing colon neoplasia than CD(HR=0.44;95%CI 0.16–1.25;P=0.12).Conclusions:PSC patients with CD appear to be associated with a lower risk of colon neoplasia and colectomy than PSC patients with UC.

关键词： primary sclerosing cholangitis ulcerative colitis Crohn’s disease colon neoplasia colectomy liver transplantation

Body awareness therapy: A new strategy for relief of symptoms in irritable bowel syndrome patients

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World Journal of Gastroenterology 2007年第23期13卷 3206-3214页

作者： EM Eriksson IE Mller RH Sderberg HT Eriksson gk Kurlberg Departments of Surgery Sahlgrenska University Hospital/stra Gteborg Sweden Departments of Medicine Sahlgrenska University Hospital/stra Gteborg Sweden

AIM: To compare irritable bowel syndrome (IBS) pa- tients with apparently healthy persons and to evaluate body awareness therapy, which is a physiotherapeutic remedy focusing on normalising tensions in the body, for the treatment of IBS with the hypothesis that altered body tension is associated with the syndrome. METHODS: Twenty-one IBS patients received body awareness therapy two hours weekly for 24 wk. At base- line as well as after 12 and 24 wk, they underwent ex- aminations including resource oriented body examination in combination with body awareness scale evaluation and f illed in gastrointestinal and psychological symptom questionnaires. Saliva cortisol was analysed. A group of 21 apparently healthy persons underwent the same ex- aminations once. RESULTS: Compared to the apparently healthy group, IBS patients scored higher at baseline for gastrointestinal and psychological symptoms. They showed more often alterations in normal body tension patterns, as well as deviating cortisol slopes in saliva. After 24 wk of body awareness therapy, their gastrointestinal and psychologi- cal symptoms were reduced overall. Somatic symptoms decreased in parallel with depressive symptoms. Whole body pain score decreased, coping ability as well as bio- chemical stress markers improved. CONCLUSION: IBS patients scored higher for gastroin- testinal and psychological symptoms, and presented with altered biochemical stress markers. Their body tension deviated compared to healthy controls. Furthermore,body awareness therapy gave relief of both somatic com- plaints, psychological symptoms and normalised body tension. These findings indicate that distorted tension constitutes an important part of the symptoms in IBS.

关键词： Irritable bowel syndrome Pain Cortisol Physiotherapy Body awareness therapy Psychosomatics Gastrointestinal tract Stress

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自制一台50％的电脑

大众电脑 2002年第8期 68-74页

作者： gk

Plant growth-promoting rhizobacteria(PGPR)and its mechanisms against plant diseases for sustainable agriculture and better productivity

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BIOCELL 2022年第8期46卷 1843-1859页

作者： PRANAB DUTTA GOMATHY MUTHUKRISHNAN SABARINATHAN KUTALINGAM GOPALASUBRAMAIAM RAJAKUMAR DHARMARAJ ANANTHI KARUPPAIAH KARTHIBA LOGANATHAN KALAISELVI PERIYASAMY MARUMUGAM PILLAI gk UPAMANYA SARODEE BORUAH LIPA DEB ARTI KUMARI MADHUSMITA MAHANTA PUNABATI HEISNAM AK MISHRA School of Crop Protection Central Agricultural University(Imphal)UmiamIndia Department of Soil Science and Agricultural Chemistry Agricultural College and Research InstituteTamil Nadu Agricultural UniversityKoyingbatoreIndia Department of Crop physiology Agricultural College and Research InstituteTamil Nadu Agricultural UniversityKoyingbatoreIndia Departments of Pulses Tamil Nadu Agricultural UniversityCoimbatoreKoyingbatoreIndia Department of Environmental Sciences Horticultural College and Research InstituteTamil Nadu Agricultural UniversityKoyingbatoreIndia Department of Plant pathology Assam Agricultural UniversityDhubriIndia KVK-Tinsukia Assam Agricultural UniversityTinsukiaIndia Department of Plant Pathology Central Agricultural University(Imphal)PasighatIndia Department of Plant Pathology Dr Rajendra Prasad Central Agricultural UniversityBiharIndia

Plant growth-promoting rhizobacteria(PGPR)are specialized bacterial communities inhabiting the root rhizosphere and the secretion of root exudates helps to,regulate the microbial dynamics and their interactions with the *** bacteria viz.,Agrobacterium,Arthobacter,Azospirillum,Bacillus,Burkholderia,Flavobacterium,Pseudomonas,Rhizobium,etc.,play important role in plant growth *** addition,such symbiotic associations of PGPRs in the rhizospheric region also confer protection against several diseases caused by bacterial,fungal and viral *** biocontrol mechanism utilized by PGPR includes direct and indirect mechanisms direct PGPR mechanisms include the production of antibiotic,siderophore,and hydrolytic enzymes,competition for space and nutrients,and quorum sensing whereas,indirect mechanisms include rhizomicrobiome regulation *** of root exudates,phytostimulation through the release of phytohormones viz.,auxin,cytokinin,gibberellic acid,1-aminocyclopropane-1-carboxylate and induction of systemic resistance through expression of antioxidant defense enzymes viz.,phenylalanine ammonia lyase(PAL),peroxidase(PO),polyphenyloxidases(PPO),superoxide dismutase(SOD),chitinase andβ-*** the suppression of plant diseases potent bio inoculants can be developed by modulating the rhizomicrobiome through rhizospheric *** addition,understandings of different strategies to improve PGPR strains,their competence,colonization efficiency,persistence and its future implications should also be taken into consideration.

关键词： Plant growth-promoting rhizobacteria Biocontrol Plant diseases PGPR mechanisms Sustainable agriculture