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Reviewing the insights of SARS-CoV-2:Its epidemiology,pathophysiology,and potential preventive measures in traditional medicinal system

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Clinical Traditional Medicine and Pharmacology 2024年第3期5卷 96-110页

作者： Munish sharma Amit Kumar sharma Simran sharma Arvind Kumar sharma Munish sharma Kamal Kant sharma munit sharma Department of Plant Sciences Central University of Himachal PradeshShahpurKangra176206Himachal PradeshIndia Department of Animal Science Central University of Himachal PradeshShahpur Campus176206KangraIndia Department of Earth and Environmental Sciences Central University of Himachal PradeshShahpur Campus176206KangraIndia Department of Zoology and Environmental Science Gurukula Kangri(Deemed to be University)Haridwar249404UttarakhandIndia Department of Botany and Microbiology Gurukula Kangri(Deemed to be University)Haridwar249404UttarakhandIndia Department of Botany Thakur P.G.College of EducationDhaliara177103DehraHimachal PradeshIndia

Background:The severe acute respiratory syndrome Coronavirus-2 causing COVID-19 viral infection was first reported in late December 2019,spreading swiftly across all over the *** declared it a pandemic by March *** problems emerged worldwide healthcare system and economic burden due to viral *** transmission rate and infectious nature make COVID-19 *** managing outbreak and controlling spread is *** valiant efforts to contain the COVID-19 outbreak,the situation has deteriorated to the point that there were no viable preventive therapies to treat this *** effective treatment for COVID-19 has been a complex and ongoing ***:The aim of this systematic review is to evaluate the structure,epidemiology,pathophysiology,po-tential therapeutic treatments,and preventive measures adopted in Traditional Chinese Medicine(TCM)in the management of Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2)***:A systematic methodology has been adopted in this study following PRISMA *** key-words like“COVID-19”“SARS-CoV-2”“Coronavirus”and“Traditional Chinese Medicine”were searched in var-ious databases like ScienceDirect,Google Scholar,PubMed,and ResearchGate during the time span of *** trials and studies relevant to this study were identified through a systematic search strategy fol-lowing PRISMA ***:In this systematic review,after careful evaluation and reviewing of literature through PRISMA guidelines,145 relevant studies were identified,reviewed and included in this systematic review.A detailed study has been summarized on virus structure,etiology,epidemiology characteristics,pathophysiology,and potential therapeutic treatments and preventive measures adopted in traditional medicinal system in the treatment of infected COVID-19 ***:SARS-CoV-2 transmission dynamics and pathogenesis were revealed by the etiology ***-

关键词： COVID-19 SARS-CoV-2 Structure Epidemiology Pathophysiology Traditional medicine

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Reviewing the medicinal potential of Valeriana jatamansi Jones:its traditional uses,phytochemistry,and pharmacological activities

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TMR Pharmacology Research 2023年第4期3卷 57-64页

作者： Ritika Dhiman Munish sharma munit sharma Munish sharma Department of Plant Sciences Central University of Himachal PradeshShahpur 176206India Department of Botany Thakur P.G.College of EducationDehra 177103India

Objectives:To gather updated information on the traditional uses,phytochemistry,and pharmacological activities of Valeriana jatamansi ***:*** is indigenous to the Himalayas immensely used as traditional folk *** contains a variety of secondary metabolites that give it a high medicinal and therapeutic *** the purpose of collecting relevant information on ***,a comprehensive literature search was *** on ethnobotanical sources and historical records,traditional uses were *** articles and databases were consulted for phytochemical *** order to assess the plant’s therapeutic properties,pharmacological studies were ***:The botanical is known for its ethnobotanical uses ranging from sedative and anxiolytic effects to treating insomnia,epilepsy,and gastrointestinal *** healing practices rely heavily on its traditional *** on the phytochemical analysis,it contains a diverse array of bioactive compounds,including sesquiterpenoids and *** acid and jatamansinol,among other compounds,contribute to its therapeutic potential.A broad spectrum of pharmacological activities is found including anxiety-relieving,sedative,anti-inflammatory,neuroprotective,and antimicrobial ***:Based on the evidence supporting ethnomedicinal uses of ***,its immense biopotential and multiple pharmacological roles,standard clinical trials are required to evaluate its therapeutic potential.

关键词： Valeriana jatamansi traditional knowledge phytochemistry pharmacology essential oils

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