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Efficacy of gabapentin for low back pain at a tertiary hospital: A prospective observational study

Journal of Acute Disease 2022年第3期11卷 101-106页

作者： Navaneetha Krishnan Subramanian VV.Ramesh Chandra Karthikeyan Elumalai Narahari N Palei Tiruveedi Kusuma Vadlamuri Venkata Prasad Yellanti Bala Venkata Bhargav Phani mungara yeshwanth sai Pradeep Battula Anna Balaji Department of Pharmacology Dr.Kalam College of PharmacyPeriyanayagipuram 614623India Department of Neurosurgery Sri Venkateswara Institute of Medical SciencesTirupati 517102India Faculty of Pharmacy Bharath Institute of Higher Education and ResearchSelaiyur 600073India School of Pharmacy the Neotia UniversitySarisha 743368India Department of Pharmacy Practice Sree Vidyanikethan College of PharmacyTirupati 517102India Departments of Pharmacy Practice Santhiram College of PharmacyNandyal 518501India Departments of Pharmaceutics Sree Vidyanikethan College of PharmacyTirupati 517102India

Objective:To assess the efficacy of gabapentin in the treatment of low back pain ***:This prospective observational study was conducted over 6 months to assess the efficacy of gabapentin in patients suffering from low back *** medical history,pain severity by Visual Analogue scale(VAS)and sleep quality by Pittsburgh Sleep Quality Index(PQSI)were *** scores and PQSI scores before and after gabapentin treatment were compared,and gabapentin satisfaction post treatment were ***:This study included 100 low back pain patients with 65 males and 35 females,and the mean age was(39.0±10.5)*** commonest presentation was non-radiating low back pain(40%).The mean VAS score and the mean PQSI score in the study before treatment were 7.70±1.91 and 10.95±5.02,*** treatment with gabapentin,the mean VAS score and the mean PQSI score decreased to 2.75±1.79 and 4.90±2.20,respectively,and the differences before and after the treatment were significantly different(both P=0.001).Overall,62%of the patients were extremely satisfied with gabapentin because they reported no adverse drug ***,31%of the patients were satisfied and 7%were strongly dissatisfied with the ***:Gabapentin can improve sleep quality and reduce lower back pain as measured by the VAS and *** efficacy of this drug is relatively good,but further improvement is required.

关键词： Gabapentin Low back pain Sleep Pittsburgh Sleep Quality Index Visual Analogue Scale

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