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Reduced protein diet with near ideal amino acid profile improves energy efficiency and mitigate heat production associated with lactation in sows

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Journal of Animal Science and Biotechnology 2020年第2期11卷 587-601页

作者： Sai Zhang Jay S.Johnson Mu Qiao Nathalie l.Trottier Department of Animal Science Michigan State UniversityEast Lansing 48824USA USDA-ARS livestock Behavior Research Unit West Lafayette 47907USA Institute of Animal Husbandry and Veterinary Hubei Academy of Agricultural SciencesWuhan 430064China

Background:The study objective was to test the hypothesis that 1)lowering dietary crude protein(CP)increases dietary energetic efficiency and reduces metabolic heat associated with lactation,and 2)excessive dietary leucine(leu)supplementation in a.l.w CP diet decreases dietary energetic efficiency and increases metabolic heat associated with ***:Fifty-four lactating multiparous Yorkshire sows were a.l.tted to 1 of 3 isocaloric diets(10.80 MJ/kg net energy):1)control(CON;18.75%CP),2)reduced CP with a near ideal or optimal AA profile(OPT;13.75%CP)and 3)diet OPT with excessive leu(OPTlEU;14.25%CP).Sow body weight and backfat were recorded on day 1 and 21 of lactation and piglets were weighed on day 1,4,8,14,18,and 21 of *** balance was measured on sows during ea.l.(day 4 to 8)and peak(day 14 to18)lactation,and milk was sampled on day 8 and ***:Over 21-day lactation,sows fed OPT lost body weight and body lipid(Plactation,sows fed OPT had higher milk energy output(PlEU tended(P=0.07)to have less milk energy output than OPT and did not differ from *** energy retention was lower(PlEU compared to CON sows,and did not differ between OPTlEU and OPT *** fed OPT had higher(Plk production compared to *** production associated with lactation was lower(Plower(P=0.082),respectively,in OPT and OPTlEU compared to CON ***:The OPT diet,in peak lactation,improved dietary energy utilization for lactation due to less urinary energy and metabolic heat loss,and triggered dietary energy deposition into milk at the expense of maternal lipid *** supplementation above requirement may reduce dietary energy utilization for lactation by decreasing the energy partitioning towards milk,partia.l. explaining the effectiveness of OPT diet over CON diets.

关键词： Amino acid Energy balance Heat production lactating sows leucine Reduced protein diet

Preferences for pre-exposure prophylaxis among U.S. military men who have sex with men:results of an adaptive choice based conjoint analysis study

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Military Medical Research 2022年第2期9卷 141-151页

作者： JoséI.Gutierrez Alex Dubov Frederick l.Altice David Vlahov Yale School of Nursing 400 West Campus DriveOrangeCT 06477USA Philip R.lee Institute for Health Policy Studies University of CaliforniaSan Francisco3333 California StSan FranciscoCA 94118USA loma.l.nda University Griggs Hall 11065Loma LindaCA 92350USA Yale School of Medicine Section of Infectious Diseases135 College StreetSuite 323New HavenCT 06510USA Department of Epidemiology-Microbial Diseases Yale School of Public Health60 College StNew HavenCT 06510USA

Background: Pre-exposure prophylaxis(PrEP) prevents human immunodeficiency virus(HIV) infection, but its use remains low among U.S. military men who have sex with men(MSM), likely due to mis-matching with personal preferences. We conducted a study to characterize preferences to PrEP measures within this ***: HIV-negative military MSM were recruited through a closed, lesbian, Gay, Bisexual, and Transgendered(lGBT) military social media group. The survey was anonymous, and consisted of five experimenta.l. varied attributes in service delivery: dosing method, provider type, visit location, lab work evaluation location, and dispensing *** importance and part-worth utility scores were generated using hierarchical bayes(HB) estimation, and the randomized first choice model was used to examine participation interest across eight possible PrEP program ***: A total of 429 participants completed the survey. Among the eight scenarios with varying attributes, the most preferred scenario featured a da.l. ta.l.t, PrEP injection or implant, along with a military provider, smartphone/telehealth visit, and on-base locations for lab evaluation and medication pick-up. The results also emphasized the importance for providers to be familiar with PrEP prescription knowledge, and to provide interactions sensitive to sexual identity and mental ***: A PrEP program consisting of da.l. ta.l.t is preferred in military healthcare settings is preferred. longacting implants and injections are also desired.

关键词： Conjoint analysis Pre-exposure prophylaxis Preference Decision science Human immunodeficiency virus Military health Infectious disease

Training β relaxation to rejuvenate meta.l.c glasses

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Journal of Materials Science & Technology 2023年第27期158卷 53-62页

作者： l.T.Zhang Yun-Jiang Wang Y.Yang J.C.Qiao School of Mechanics Civil Engineering and ArchitectureNorthwestern Polytechnical UniversityXi’an 710072China State Key laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing 100190China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China Department of Mechanical Engineering College of EngineeringCity University of Hong KongTat Chee AvenueKowloon TongKowloonHong Kong SARChina Department of Materials Science and Engineering College of EngineeringCity University of Hong KongTat Chee AvenueKowloon TongKowloonHong Kong SARChina Innovation Center NPU-ChongqingChongqing 401135China

In the current work,we demonstrated that the rejuvenation of meta.l.c glasses can be achieved through training theβrelaxation *** the increase in the training frequency,a transition from structural relaxation to rejuvenation can be *** rejuvenation treatment is unexpected due to it occurs at a relatively sma.l.cyclic strain of 0.2%.Rejuvenation is beneficial to increase the relaxation enthalpy and promotes the decoupling of theβrelaxation process andαrelaxation process.A cluster ofβrelaxation time curves are formulated to describe any energetic state between ultrasta.l. and ultimately rejuvenated meta.l.c *** addition,rejuvenation expands the distribution ofβrelaxation process,anelastic and viscoplastic components during the deformation process.

关键词： Meta.l.c glass βrelaxation Rejuvenation Structural heterogeneity

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赶黄草化学成分及药理活性研究进展

辽宁大学学报（自然科学版） 2024年第2期51卷 121-129页

作者：吕晶田新强项峥陈长兰辽宁大学药学院辽宁沈阳110036

赶黄草(Penthorum chinense Pursh)为传统苗族药物,是一种民间用于预防治疗肝病的“药食同源”植物,性温味甘,具有清热解毒、利水消肿、平肝等功效.现代天然药物化学研究表明,赶黄草含有丰富的活性成分,包括黄酮类、木脂素类、有机酸类... 详细信息

赶黄草(Penthorum chinense Pursh)为传统苗族药物,是一种民间用于预防治疗肝病的“药食同源”植物,性温味甘,具有清热解毒、利水消肿、平肝等功效.现代天然药物化学研究表明,赶黄草含有丰富的活性成分,包括黄酮类、木脂素类、有机酸类、香豆素类等化学成分,具有抗肿瘤、抗氧化、抗炎和肝损伤的保护作用等多种药理活性,药食用价值较高.近年来,虽然赶黄草的化学成分及其药理作用研究逐渐深入,然而相关综述较少.本文对国内外研究成果进行了综述,以期为赶黄草的药理作用机制研究及“药食同源”新型保健产品的开发提供参考.

关键词：赶黄草化学成分药理活性药食同源

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li-intercalation in Silicon Anodes:A Cha.l.nging Route Towards 3D-Integrated a.l.solid-state Batteries

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复旦学报（自然科学版） 2007年第5期46卷 688-页

作者： P.H.l.Notten l.Baggetto R.A.H.Niessen D.Danilov Eindhoven University of Technology Philips Research laboratories

1 Results Micro-batteries are expected to become more and more important in numerous sma.l.sized devices,like medical implanta.l.s,biosensors,hearing aids and autonomous network *** for these electronic applications is that they have to operate autonomously and *** to these requirements thin film power sources need to be rechargea.l.,mechanica.l. sta.l. for a.l.ng period of time and have a.l.ng cycle *** the average energy consumption of these future devices will be rathe...

关键词： li-ion batteries 3D-integration a.l.solid-state

Effects of equine-assisted interventions on older adults’health:A systematic review

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International Journal of Nursing Sciences 2022年第4期9卷 542-552页

作者： léa Badin Émilie Alibran Kristell Pothier Nathalie Ba.l.y University of Tours EA 2114 PAVEA LaboratoryToursFrance

Objective:Equine-assisted interventions(EAI)can improve a variety of health problems in older adults and thus promote their *** systematic review aimed to synthesize studies on EAI to understand better their effects on the health of older ***:A systematic search guided by the PRISMA 2020 approach was performed on specific databases:Medline(PubMed),EMBASE,PsycINFO,and Cochrane ***-reviewed articles published in the English language from inception to June 2022 were *** quality was esta.l.shed using the modified version of the Downs and Black ***:A total of 244 studies were retrieved,and 13 eligible studies were fina.l. *** health domains were investigated:physical(balance,gait,and muscular strength),psychological(quality of life and cognitive assessment),and physiological(hormonal measures,cerebral and muscular activity).Among the eight studies investigating the physical dimension,four studies highlighted a positive effect of EAI on balance,four for gait,and three for *** the three studies investigating the psychological dimension,two studies showed a positive effect of EAI on quality of ***,the four studies investigating the physiological dimensions a.l.demonstrated a positive effect of EAI on hormonal measures and cerebral and muscular ***:Nevertheless,this systematic review provides promising findings regarding the positive effects of EAI on physical,psychological,and physiological health in older *** on EAI should therefore be pursued rigorously to promote this non-pharmacological intervention in an older adult population.

关键词： Animal assisted therapy Aged Equine assisted therapy Health promotion

Utilization of clean energy and future trend of Antarctic research stations

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Advances in Polar Science 2021年第3期32卷 185-194页

作者： lI Zhao lÜDongxiang SUN Zilu lI Chuan The 18th Research Institute of China Electronics Technology Group Corporation Tianjin 300384China

The polar regions are rich in resources with high scientific *** scientific research is of great significance to natural environment,climate,astronomy and *** scientific research is closely related to polar energy *** research stations still use fossil fuels as the main source of power *** kind of power supply not only pollutes the environment,but also consumes a.l.t of manpower and material *** a kind of renewa.l. energy such as solar energy and wind energy,renewa.l. energy not only has the characteristics of sustaina.l. development,but also has the characteristics of local power generation and transportation cost *** present,several countries have started the construction and application of polar renewa.l. energy,and achieved good results in some Antarctic *** on the investigation and summary of the application of renewa.l. energy in various countries,this paper discusses the development trend of polar energy supply in the future,and provides a clear idea and direction for the development of polar renewa.l. energy.

关键词： Antarctic research station renewa.l. energy wind power solar power

SPP1和miR-340-5p在甲状腺癌中的表达水平及预后价值

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热带医学杂志 2024年第4期24卷 527-531页

作者：吕文豪王江芬张亚芬山西医科大学第五临床医学院乳腺外科山西太原030012 山西省人民医院乳腺外科山西太原030012

目的分析分泌磷蛋白1(SPP1)、微小RNA-340-5p(miR-340-5p)在甲状腺癌中的表达水平,为临床提高甲状腺癌早期诊断及预后提供帮助。方法选取山西医科大学第五临床医学院乳腺外科2018年3月-2020年5月期间收治的119例分化型甲状腺癌(DTC)患... 详细信息

目的分析分泌磷蛋白1(SPP1)、微小RNA-340-5p(miR-340-5p)在甲状腺癌中的表达水平,为临床提高甲状腺癌早期诊断及预后提供帮助。方法选取山西医科大学第五临床医学院乳腺外科2018年3月-2020年5月期间收治的119例分化型甲状腺癌(DTC)患者作为研究组,根据随访期间复发转移及死亡情况分为预后良好组(n=84)和预后不良组(n=35),另选取一般资料与研究组相匹配的119例甲状腺良性病变患者作为对照组。采用Pearson法分析血清SPP1和miR-340-5p表达水平的相关性;采用多因素logistic回归分析影响DTC患者预后的相关因素;采用受试者工作特征(ROC)曲线分析血清SPP1、miR-340-5p对DTC患者预后的预测效能。结果研究组血清SPP1和miR-340-5p表达水平高于对照组,差异均有统计学意义(t=15.732、10.111,P均<0.001)。DTC患者血清SPP1与miR-340-5p表达水平成正相关(r=0.584,P<0.05)。预后不良组血清SPP1和miR-340-5p表达水平高于预后良好组,差异均有统计学意义(t=7.497、4.938,P均<0.001)。预后不良组发生淋巴结转移、TNM分期为Ⅲ+Ⅳ期的患者所占比例显著高于预后良好组,差异均有统计学意义(χ^(2)=11.297、6.802,P均<0.05)。淋巴结转移(OR=1.901)、TNM分期为Ⅲ+Ⅳ期(OR=2.178)、SPP1(OR=1.541)及miR-340-5p(OR=2.104)为DTC患者发生不良预后的危险因素(P均<0.05)。血清SPP1和miR-340-5p预测DTC患者预后状态的曲线下面积(AUC)分别为0.829(95%CI:0.749~0.892)、0.698(95%CI:0.607~0.779),二者联合预测的AUC为0.908(95%CI:0.841~0.953),二者联合优于SPP1和miR-340-5p各自单独检测(Z=2.410、3.566,P均<0.05)。结论血清SPP1和miR-340-5p表达水平与甲状腺癌的发生发展相关,二者联合检测对甲状腺癌患者预后状态具有较高的预测效能。

关键词：分泌磷蛋白1 微小RNA-340-5p 甲状腺癌

The preferential growth and related textural evolution during static recrysta.l.zation in a cold-rolled Mg-Zn-Gd a.l.y

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Journal of Magnesium and a.l.ys 2021年第3期9卷 818-828页

作者： l.Y.Zhao H.Yan R.S.Chen En-Hou Han The Group of Magnesium a.l.ys and Their Applications Institute of Metal ResearchChinese Academy of Sciences62 Wencui RoadShenyang 110016China School of Materials Science and Engineering University of Science and Technology of China72 Wenhua RoadShenyang 110016China

The grain growth process plays an important role in the texture formation in magnesium *** microstructural and micro-textural evolution of a cold-rolled Mg-Zn-Gd a.l.y during annealing at 350℃for 60-190 min were tracked by quasi-in-situ electron backscatter diffraction *** results show that grain growth takes place gradua.l. with the annealing time ***,the TD-split texture maintains the texture type but alters in three aspects-the increased tilting angle,the decreased pole intensity and the widened distribution of high-intensity *** with their c-axis tilting 45-70°from normal direction show preferential growth which is closely associated with the texture *** original grain size advantage is one of the important factors leading to the growth advantage,some grain boundaries,such as 50-60°[1^(-)21^(-)0],50-60°[2750],60-70°[1^(-)21^(-)0](18b),and 70-80°[1^(-)01^(-)0](10)are also considered to be related to this preferential growth.

关键词： Grain growth Preferential growth Texture Static recrysta.l.zation Magnesium a.l.ys