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High-dose-rate intraluminal brachytherapy during preoperative chemoradiation for locally advanced rectal cancers

World Journal of Gastroenterology 2010年第35期16卷 4436-4442页

作者： Mutahir Ali Tunio Mansoor Rafi Altaf Hashmi Rehan Mohsin Abdul Qayyum mujahid hasan Amjad Sattar Muhammad Mubarak Department of Radiation Oncology Sindh Institute of Urology and Transplantation Department of Surgical Oncology Sindh Institute of Urology and Transplantation Department of Medical Oncology Sindh Institute of Urology and Transplantation Department of Gastroenterology Sindh Institute of Urology and Transplantation Department of Radiology Sindh Institute of Urology and Transplantation Department of Pathology Sindh Institute of Urology and Transplantation

AIM:To determine the feasibility and safety of high dose rate intraluminal brachytherapy(HDR-ILBT) boost during preoperative chemoradiation for rectal ***:Between 2008 and 2009,thirty-six patients with locally advanced rectal cancer(≥ T3 or N+),were treated initially with concurrent capecitabine(825 mg/m2 oral twice daily) and pelvic external beam radiotherapy(EBRT)(45 Gy in 25 fractions),then were randomized to group A;HDR-ILBT group(n = 17) to receive 5.5-7 Gy×2 to gross tumor volume(GTV) and group B;EBRT group(n = 19) to receive 5.4 Gy×3 fractions to GTV with *** patients underwent total mesorectal ***:Grade 3 acute toxicities were registered in 12 patients(70.6%) in group A and in 8(42.1%) in group *** pathologic response of T stage(ypT0) in group A was registered in 10 patients(58.8%) and in group B,3 patients(15.8%) had ypT0(P < 0.0001).Sphincter preservation was reported in 6/9 patients(66.7%) in group A and in 5/10 patients(50%) in group B(P < 0.01).Overall radiological response was 68.15% and 66.04% in Group A and B,*** a median follow up of 18 mo,late grade 1 and 2 sequelae were registered in 3 patients(17.6%) and 4 patients(21.1%) in the groups A and B,***:HDR-ILBT was found to be effective dose escalation technique in preoperative chemoradiation for rectal cancers,with higher response rates,downstaging and with manageable acute toxicities.

关键词： High dose rate Intraluminal brachytherapy boost Locally advanced rectal cancer Preoperative chemoradiation

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A Holistic Secure Communication Mechanism Using a Multilayered Cryptographic Protocol to Enhanced Security

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Computers, Materials & Continua 2024年第3期78卷 4417-4452页

作者： Fauziyah Zhaoshun Wang mujahid Tabassum School of Computer and Communication Engineering University of Science and TechnologyBeijing100000China Noroff School of Technology and Digital Media(Noroff Accelerate) Noroff University CollegeKristiansand4612Norway

In an era characterized by digital pervasiveness and rapidly expanding datasets,ensuring the integrity and reliability of information is *** cyber threats evolve in complexity,traditional cryptographic methods face increasingly sophisticated *** article initiates an exploration into these challenges,focusing on key exchanges(encompassing their variety and subtleties),scalability,and the time metrics associated with various cryptographic *** propose a novel cryptographic approach underpinned by theoretical frameworks and practical *** to this approach is a thorough analysis of the interplay between Confidentiality and Integrity,foundational pillars of information *** method employs a phased strategy,beginning with a detailed examination of traditional cryptographic processes,including Elliptic Curve Diffie-Hellman(ECDH)key *** also delve into encrypt/decrypt paradigms,signature generation modes,and the hashes used for Message Authentication Codes(MACs).Each process is rigorously evaluated for performance and *** gain a comprehensive understanding,a meticulously designed simulation was conducted,revealing the strengths and potential improvement areas of various ***,our cryptographic protocol achieved a confidentiality metric of 9.13 in comprehensive simulation runs,marking a significant advancement over existing ***,with integrity metrics at 9.35,the protocol’s resilience is further *** metrics,derived from stringent testing,underscore the protocol’s efficacy in enhancing data security.

关键词： Cryptographic security privacy preservation decryption integrity

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A Stochastic Model to Assess the Epidemiological Impact of Vaccine Booster Doses on COVID-19 and Viral Hepatitis B Co-Dynamics with Real Data

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Computer Modeling in Engineering & Sciences 2024年第3期138卷 2973-3012页

作者： Andrew Omame mujahid Abbas Dumitru Baleanu Department of Mathematics Federal University of TechnologyOwerri460114Nigeria Abdus Salam School of Mathematical Sciences Government College UniversityLahore54000Pakistan Department of Mathematics Government College UniversityLahore54000Pakistan Department of Computer Science and Mathematics Labanese American UniversityBeirutLebanon Institute of Space Sciences Magurele-BucharestRomania Department of Medical Research China Medical University HospitalChina Medical UniversityTaichung40402Taiwan

A patient co-infected with COVID-19 and viral hepatitis B can be atmore risk of severe complications than the one infected with a single *** study develops a comprehensive stochastic model to assess the epidemiological impact of vaccine booster doses on the co-dynamics of viral hepatitis B and *** model is fitted to real COVID-19 data from *** proposed model incorporates logistic growth and saturated incidence *** analyses using the tools of stochastic calculus,are performed to study appropriate conditions for the existence of unique global solutions,stationary distribution in the sense of ergodicity and disease *** stochastic threshold estimated from the data fitting is given by:R_(0)^(S)=*** assessments are implemented to illustrate the impact of double-dose vaccination and saturated incidence functions on the dynamics of both *** effects of stochastic white noise intensities are also highlighted.

关键词： Viral hepatitis B COVID-19 stochastic model extinction ergodicity real data

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Bio-inspired barnacle cement coating of biodegradable magnesium alloy for cerebrovascular application

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Rare Metals 2024年第10期43卷 5164-5185页

作者： Hang Li Fei Wang Xiao-Jing Sun Liu-Jie Qi Jing-An Li mujahid Iqbal Shao-Kang Guan School of Material Science and Engineering Zhengzhou University Henan Key Laboratory of Advanced Magnesium Alloy&Key Laboratory of Materials Processing and Mold (Ministry of Education) Zhengzhou University Department of Physics University of Agriculture Faisalabad

Ischemic stroke is increasing worldwide, and stent intervention has gradually become one of the effective treatments. Owing to its good mechanical properties and biocompatibility, biodegradable Mg-Zn-Y-Nd alloy(ZE21B) has good application prospects in vascular ***, too fast degradation and delayed endothelialization are the bottleneck problem to limit its further application. In this study, the bio-inspired coating barnacle cement cp19k is constructed on ZE21B surface through electrostatic spraying to improve the corrosion resistance and pro-endothelialization ability. The coating was evaluated through electrochemistry, static immersion corrosion,in vitro blood experiments and cell experiments. Cp19k effectively improved the corrosion resistance of the substrate ZE21B, reduced the degradation rate, improved endothelial cell proliferation and migration capabilities,inhibited smooth muscle cells proliferation and regulated contractile phenotype, inhibited macrophage adhesion,regulated macrophage M2 phenotype, and reduced the expression of inflammatory factor of TNF-a and inhibited fibroplasia in vivo. Our data indicated that the barnacle cement cp19k coating had potential application on the surface modification of Mg alloy cerebrovascular stent.

关键词： Barnacle cement cp19k Biodegradable magnesium alloy Cerebrovascular stent M2 phenotype Pro-endothelialization

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Innovative Solutions for High-Performance Silicon Anodes in Lithium-Ion Batteries:Overcoming Challenges and Real-World Applications

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Nano-Micro Letters 2024年第9期16卷 341-384页

作者： Mustafa Khan Suxia Yan mujahid Ali Faisal Mahmood Yang Zheng Guochun Li Junfeng Liu Xiaohui Song Yong Wang Institute for Energy Research Jiangsu UniversityZhenjiang 212013JiangsuPeople’s Republic of China School of Energy and Power Engineering Jiangsu UniversityZhenjiang 212013JiangsuPeople’s Republic of China School of Materials Science and Engineering Hefei University of TechnologyHefei 230009AnhuiPeople’s Republic of China

Silicon(Si)has emerged as a potent anode material for lithium-ion batteries(LIBs),but faces challenges like low electrical conductivity and significant volume changes during lithiation/delithiation,leading to material pulverization and capacity *** research on nanostructured Si aims to mitigate volume expansion and enhance electrochemical performance,yet still grapples with issues like pulverization,unstable solid electrolyte interface(SEI)growth,and interparticle *** review delves into innovative strategies for optimizing Si anodes’electrochemical performance via structural engineering,focusing on the synthesis of Si/C composites,engineering multidimensional nanostructures,and applying non-carbonaceous *** a stable SEI is vital to prevent electrolyte decomposition and enhance Li^(+)transport,thereby stabilizing the Si anode interface and boosting cycling Coulombic *** also examine groundbreaking advancements such as self-healing polymers and advanced prelithiation methods to improve initial Coulombic efficiency and combat capacity *** review uniquely provides a detailed examination of these strategies in real-world applications,moving beyond theoretical *** offers a critical analysis of these approaches in terms of performance enhancement,scalability,and commercial *** conclusion,this review presents a comprehensive view and a forward-looking perspective on designing robust,high-performance Si-based anodes the next generation of LIBs.

关键词： Silicon anode Energy storage Nanostructure Prelithiation Binder

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Deterministic relation between thermalphonon dressings and a non-Hermitian multi-Fano interferences router in iondoped microcrystals

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Chip 2024年第1期3卷 24-34页

作者： Huanrong Fan Faizan Raza Anas mujahid Peng Li Yafen Wang Haitian Tang Muhammad Usman Bo Li Changbiao Li Yanpeng Zhang Key Laboratory for Physical Electronics and Devices of the Ministry of Education&Shaanxi Key Lab of Information Photonic Technique Xi’an Jiaotong UniversityXi’an 710049China Center for Regenerative and Reconstructive Medicine Med-X InstituteThe First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061China State Key Lab of Modern Optical Instrumentation Centre for Optical and Electromagnetic ResearchCollege of Optical Science and EngineeringInternational Research Center for Advanced PhotonicsZhejiang UniversityHangzhou 310058China

The multi-Fano interference,which is obtained through the simultaneous acquisition of bright and dark states in different phase transitions of Eu3+:BiPO4(7:1,6:1,1:1,and 0.5:1)and Eu3+:NaYF4(1:1/4)crystals,were reported in this *** spontaneous four-wave mixing and multidressed fluorescence(multiorder)were adopted to optimize the strong photon–phonon nested dressing effect,which results in more obvious multi-Fano ***,the multi-Fano is produced through interference in continuous and multibound ***,five multi-Fano dips are originated from the nested five dressings(one photon and four phonons)under symmetrical splitting of 7F1 energy *** is found that the pure H-phase(0.5:1)sample exhibits the strongest photon–phonon dressed effect(five Fano dips).Further,high-order non-Hermitian exceptional points in multi-Fano interference were investigated by adjusting the ratio of Rabi frequency to dephase rate through nested photon and phonon *** experimental results are validated by theoretical simulations,which may be applied to designing optoelectronic devices such as non-Hermitian multi-Fano interferences(multichannel)router.

关键词： Multi-Fano interferences Thermal-phonon dressings Non-Hermitian Router

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面向膜蒸馏的抗润湿、抗污染、抗结垢新型膜研究进展

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膜科学与技术 2024年第1期44卷 157-167页

作者：王超赵一 Muhammad mujahid 任龙飞邵嘉慧上海交通大学环境科学与工程学院上海200240

膜蒸馏(MD)作为一种有前景的高盐废水处理技术而受到广泛关注.然而,由于实际废水成分复杂,MD的实际应用面临膜润湿、膜污染和膜结垢三大关键挑战,易导致膜通量和选择性降低,甚至膜失效.本文首先简述不同种类污染物诱导的膜润湿、污染和... 详细信息

膜蒸馏(MD)作为一种有前景的高盐废水处理技术而受到广泛关注.然而,由于实际废水成分复杂,MD的实际应用面临膜润湿、膜污染和膜结垢三大关键挑战,易导致膜通量和选择性降低,甚至膜失效.本文首先简述不同种类污染物诱导的膜润湿、污染和结垢的特点及其形成原因.随后,重点介绍了目前抗润湿、抗污染、抗结垢新型膜的研究进展,包括超疏水膜、全疏膜、常规Janus膜和致密Janus膜的设计原则、抗性机理及其适用范围.此外,讨论了通过对进料预处理、操作条件调控的辅助手段以及膜再生来进一步保证MD长期运行的稳定性.

关键词：膜蒸馏润湿污染结垢新型膜

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Evaluation of the Neurodevelopmental Outcome of Toddlers with Spinal Dysraphism after Surgical Repair Using ASQ-3^™ Scores

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Open Journal of Modern Neurosurgery 2024年第1期14卷 14-29页

作者： mujahid Imam Fawaz Eljili Marhoom Sawsan Aldeaf Ali Awad Ahmed Zidan Mohamed Mustafa Ahmed Sanna Taha Neurosurgery Department National Center for Neurological Sciences (NCNS) Khartoum Sudan Neurosurgery Department Royal Care International Hospital Khartoum Sudan Al Ribat Neurospine Center Khartoum Sudan Neurosurgery Department Haj Almardi (Al Tamyouz) Hospital Khartoum Sudan Neurosurgery Department Al Jazeera Trauma Center Khartoum Sudan

Background: Spinal dysraphism represents a wide spectrum of congenital abnormalities of the spine. Myelomeningocele is considered the most common malformation and the most common we saw in our community, with its morbidity problems seen commonly in the postoperative period. ASQ-3TM Scores are the ages and stages questionnaire, third edition, and represent a tool to assess the development progress, especially in toddlers. Objectives: Evaluation of neurodevelopmental outcome among Sudanese toddlers with spinal dysraphism after surgical closure with or without a VP shunt using ASQ-3TM Scores. Methodology: This is a retrospective hospital-based study of 84 patients who underwent myelomeningocele repair at the National Center for Neurological Sciences (NCNS) during the period from 2017 up to 2019. Data were collected through a constructed questionnaire, including ASQ-3TM Scores. Data were processed and analyzed using the Statistical Package for Social Science (SPSS) computer program. Version 25. Results: 84 patients were included in this study;all patients were diagnosed with spinal dysraphism. Out of them, 51 (60.7%) were 2 years old, 33 (39.3%) were 3 years old, 45 (53.6%) were male, 45 (53.6%) of patients mothers attended ANC irregularly, and 54 (64.3%) their mothers didn’t receive folate supplements. 44 (52.3%) of patients underwent MMC repair only, while 40 (47.7%) underwent MMC repair and VP shunt. The commonest postoperative complication was infection, reported in 12 (14.3%) of patients, followed by VP shunt revision in 9 (10.7%) of patients. Neurological assessment showed that the majority of patients need further assessment with a professional, 57 (67.9%) of children don’t walk, run, or climb like other toddlers as their parent’s state;also, half of patients (42, 50%) had medical problems, and 27 (32.1%) of their parent’s state that they do not talk like other toddlers their age. There was a statistically significant association

关键词： Toddlers’ Neurodevelopmental Outcome Myelomeningocele Evaluation ASQ-3™ Scores Spinal Dysraphasim Neurodevelopmental Outcome

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基于无人机遥感的作物长势监测研究进展

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江苏农业科学 2024年第8期52卷 8-15页

作者：赵胜利 mujahid Hussain 王国宾卞志豪王猛兰玉彬山东理工大学农业工程与食品科学学院山东淄博255049 山东理工大学生态无人农场研究院山东淄博255049 山东省农业航空智能装备工程技术研究中心山东淄博255049

无人机遥感技术作为一种新型的农业技术,为精准农业领域的发展提供了重要的技术支持。与传统监测方法相比,无人机遥感具有成本低、时效性强、无大气干扰、分辨率高等优点,为农业信息采集提供了新的工具。无人机农业遥感技术能够高效、... 详细信息

无人机遥感技术作为一种新型的农业技术,为精准农业领域的发展提供了重要的技术支持。与传统监测方法相比,无人机遥感具有成本低、时效性强、无大气干扰、分辨率高等优点,为农业信息采集提供了新的工具。无人机农业遥感技术能够高效、无损地精确采集农业遥感数据,对作物长势进行实时监测,为农业生产提供重要的获取空间数据途径。近年来,随着无人机技术和遥感技术的不断发展和成熟,无人机农业遥感技术的应用范围逐步扩大,涵盖了作物生长监测、精准施肥、精准灌溉、病虫害预警等多个领域。本文重点介绍无人机遥感技术在作物生长监测中的应用,主要介绍了无人机遥感系统的组成、无人机遥感平台和传感器的类型和特点、基于无人机遥感图像数据处理的关键步骤以及作物长势监测的重要指标,综合评估了无人机遥感技术在作物长势监测方面应用的研究现状和存在的问题旨在为后续的无人机遥感技术在作物长势监测中的研究提供参考。

关键词：无人机遥感农业长势应用进展

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Dengue outbreaks in northern Nigeria: Evaluating the recommended Takeda vaccine and future prevention strategies

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World Journal of Virology 2024年第3期13卷 41-48页

作者： Ismail Rabiu Hafsat Abubakar Musa Zephaniah Isaiah mujahid Hussaini Muhammad Muhsin Umar Suleiman Mustapha Jaafaru Isah Abdullahi Aminu Shehu Mariya Abdullahi Sani College of Life Science Department of Biomedical Science and Environmental BiologyKaohsiung Medical UniversityKaohsiung 80708TaiwanChina Department of Microbiology Faculty of Life ScienceBayero University KanoKano 700006Kano StateNigeria Department of Microbiology Umaru Musa Yar’adua UniversityKatsina 820102Katsina StateNigeria Department of Microbiology Faculty of ScienceKaduna State UniversityTafawa Balewa Way 800283Kaduna StateNigeria National Reference Laboratory Nigeria Center for Disease ControlGaduwa 900231AbujaNigeria Department of Microbiology and Biotechnology Federal UniversityDutse 720223Jigawa StateNigeria Monitoring and Evaluation Unit(Jigawa State Office) World Health OrganizationDutse 720223Jigawa StateNigeria

Dengue fever,caused by the dengue virus(DENV),poses a significant public health challenge globally,with Nigeria experiencing sporadic outbreaks.A clear understanding of the dengue burden has not been achieved in Nigeria,just as in other African *** the epidemiology and burden of dengue fever is essential for effective prevention and control *** paper examines the recent dengue outbreaks in northern Nigeria,particularly in Sokoto state,and evaluates the recommended Takeda dengue vaccine(TDV)along with future prevention *** limited surveillance and underreporting,dengue fever is endemic in Nigeria(with over 5 million cases and 5000 dengue-related deaths in 2023),with recent outbreaks indicating a growing *** TDV,a live attenuated tetravalent vaccine,has shown promise in preventing dengue fever,but challenges such as vaccine acceptance and access-ibility need to be *** urbanization contributes to the disease's spread,which is influenced by factors such as population density,cultural beliefs,water storage practices,hygiene,and water supply *** prevention strategies must focus on government intervention,community practices,and innovative vector control measures to mitigate the spread of DENV in *** study will serve as a valuable reference for policy-makers,researchers,and clinicians in the management and control of DENV in Nigeria and Africa as a whole.

关键词： Dengue outbreaks Northern Nigeria Takeda dengue vaccine Vaccine acceptance Epidemiology

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