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Effect of coenzyme Q10 supplementation on post-vitrification mouse embryo development

Asian pacific Journal of reproduction 2024年第3期13卷 126-132页

作者： Anisa-Annur S Wan-Hafizah WJ Nor-Ashikin MNK muhammad-zaki r Faculty of Pharmacy and Health Sciences Royal College of Medicine PerakUniversiti Kuala Lumpur30450 IpohPerakMalaysia Maternofetal and Embryo research Group Faculty of MedicineUniversiti Teknologi MARASelangor BranchSungai Buloh Campus47000 Sungai BulohSelangorMalaysia

Objective:To investigate the effects of coenzyme Q10(CoQ10)supplementation on post-vitrification embryo development and gross ***:Balb/c mouse embryos were cultured in potassium simplex optimised medium(KSOM)with varying CoQ10 concentrations[0(control),20,40,and 60μM].The most effective CoQ10 concentration(40μM)was selected for subsequent post-vitrification morphology *** were randomly divided into four groups:Group A(non-vitrified without CoQ10),Group B(non-vitrified with CoQ10),Group C(vitrified without CoQ10),and Group D(vitrified with CoQ10),followed by vitrification at the 8-cell *** rates and development until the blastocyst stage were evaluated through morphological examinations using ASEBIr's system,distinguishing normal and abnormal ***:Supplementation of 40μM CoQ10 significantly increased blastocyst formation(95%)compared to the control group(92%),20μM(62%),and 60μM(56%)(Prification,Group D exhibited a significant increase in blastocyst formation(92%)compared to Group C(82%)(Prphological assessments indicated superior embryo quality in Group B over Group D during the cleavage stage,morula,and blastocyst(Promising potential to enhance preimplantation embryo development,increase blastocyst formation rates,and improve embryo quality *** offers a promising approach to mitigate oxidative stress on embryos,potentially improving overall assisted reproductive technology outcomes.

关键词： Coenzyme Q10 Antioxidant Embryo development Vitrification Morphology Assisted reproductive technology

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Microscale shaping and rounding of ridge arrays and star pattern features on nickel mould via electrochemical polishing

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Advances in Manufacturing 2024年第2期12卷 207-226页

作者： Sana zaki Nan Zhang Michael D.Gilchrist School of Mechanical and Materials Engineering University College DublinBelfieldDublin 4Ireland

High quality micro mould tools are critical for ensuring defect-free production of micro injection moulded *** demoulding stage of the micro injection moulding can adversely affect the surface integrity due to friction,adhesion and thermal stresses between the metallic mould and polymeric replicated *** the present work,we propose the use of precision electropolishing(EP)as a shaping and polishing process to control the draft angle and fillet radius of micro features in order to ease *** defects that occur in replicated polymer parts include cracks,burrs and distorted features.A nickel mould having multiple linear ridges and star shape patterns was designed for the present investigation to have characteristic dimensions ranging from 10μm to 150μm and with various aspect ratios to study the effect of electropolishing on modifying the shape of micro features and surface morphology.A transient 2D computational analysis has been conducted to anticipate the effect of shaping on the Ni mould after electrochemical polishing with non-uniform material removal rates,based on the distribution of current *** experimental results indicate that after shaping using EP,the draft angle of star-patterns and linear patterns can be effectively increased by approximately 3.6°,while the fillet radius increases by up to 5.0μ*** controlling the electropolishing process,the surface roughness can be maintained under 50 *** work uses a green and environmental friendly nickel sulfamate electrolyte which can be effective for shaping of nickel micro features without causing any surface deposition.

关键词： Micro feature shaping and electropolishing Micro mould tools Green electrolyte Demoulding micro patterns

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Aberrant adult neurogenesis in intractable epilepsy:can GABAergic progenitor transplantation normalize this process?

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Neural regeneration research 2024年第7期19卷 1419-1420页

作者： muhammad N.Arshad Janice r.Naegele Department of Biology Wesleyan UniversityMiddletownCTUSA Department of Neuroscience Tufts University School of MedicineBostonMAUSA

Temporal lobe epilepsy(TLE) is a common type of focal epilepsy characterized by seizure foci within the temporal *** surgical resection of the foci is an established and effective approach for controlling seizures,both temporal lobes cannot be removed,due to their prominent roles in learning and ***,seizures induce changes to the temporal lobes that contribute to hyperexcitability,including mossy fiber sprouting,astrogliosis.

关键词： epilepsy progenitor seizures

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Critical assessment of r410A alternatives for mini-split air conditioners in the Egyptian market

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Energy and Built Environment 2024年第3期5卷 426-445页

作者： Omar M.zaki Omar Abdelaziz Mechanical Power Engineering Department Faculty of EngineeringCairo UniversityGiza 12613Egypt Department of Mechanical Engineering The American University in CairoAUC AvenueNew Cairo 11835Egypt

In this study,the potential implementation of three different low-GWP refrigerants(r32,r452B,and r454B)as replacements for r410A was *** study was performed using a simulation tool developed by the authors called rACHP-Lab,which is a vapor compression system simulation tool developed based on physics-based simulation for typical mini-split air *** simulation study was carried out and validated using experimental performance data of 10 different air conditioning units available in the Egyptian *** units included fixed-speed or variable-speed compressors and operated in cooling or heating ***-in replace-ment with the new refrigerants was carried *** r32,the capacity increased between 4.9%and 13%for cooling cases,and 6.3%and 12.4%for heating ***,COP did not improve in all *** r452B and r454B with direct replacement,the capacity nearly remained the same,with an increase of COP between 1.6%and 8.0%.Soft optimization was also conducted on cooling cases where compressor suction superheat,condenser subcooling,and compressor volumetric speed were optimized to maximize COP while maintaining the original capacity of r410A.r32 showed an improvement of COP over r410A between 4.6%and 15.5%,while for r452B and r454B between 2.2%and 13.2%.

关键词： Air conditioner Heat pump Alternative refrigerants Vapor compression cycle modeling

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Design and Synthesis of NiO@Co_(3)O_(4)@ZSM-5 Heterogeneous Multitask Hollow Structures for Tandem Catalysis

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Chemical research in Chinese Universities 2024年第3期40卷 529-535页

作者： muhammad Waqas Interdisciplinary research Center for refining and Advanced Chemicals King Fahd University of Petroleum&MineralsDhahran 31261Saudi Arabia

Precipitation and impregnation procedures unevenly distribute metals on zeolite,limiting chemical transformation in Lewis-acid,Brönsted-acid and metal-catalyzed tandem ***,heterogeneous multitask transition metals oxides@zeolites are promising catalysts for sustainable processes;nevertheless,synthesis is fascinating and ***,the construction of purposely designed multitask materials segregated in selective shells reveals the remarkable spatial organization of metals-zeolite,resulting in them being suitable for a wide range of tandem *** synthesis of multi-site catalysts begins with a universal wet chemistry approach that yields nickel oxide(NiO)***,the NiO crystals are stabilized using cationic dodecyltrimethylammonium bromide,followed by achieving cross-linking carbon growth by emulsion polymerization of glucose in hydrothermal treatment to yield uniformed NiO@carbon spheres(NiO@CSs).Next,sequential adsorption of cobalt cations and colloidal ZSM-5(1%in H_(2)O,mass fraction),followed by calcination in air,yielded NiO@cobalt oxide@zeolite denoted as NiO@Co_(3)O_(4)@ZEO hollow *** hollowing mechanism and materials segregation within shells are revealed by scanning and transmission electron microscopy,thermogravimetric analysis,and X-ray *** finding advances the rational synthesis of heterogenous core-shell hollow structures for various gas phase catalytic tandem reactions to yield valuable chemicals.

关键词： Multifunctional Core-shell hollow spheres Gas-phase reaction Valuable chemical

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An integrated land change modeler and distributed hydrological model approach for quantifying future urban runoff dynamics

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Science China Earth Sciences 2024年第10期67卷 3288-3301页

作者： Asad Hussain muhammad Waseem muhammad Ajmal muhammad Atiq Ur rehman Tariq muhammad Jiaqing XIAO Tao YANG Pengfei SHI Institute for Disaster risk Management School of Geographical ScienceNanjing University of Information Science and TechnologyNanjing 210044China The National Key Laboratory of Water Disaster Prevention Hohai UniversityNanjing 210098China Yangtze Institute for Conservation and Development Hohai UniversityNanjing 210098China College of Hydrology and Water resources Hohai UniversityNanjing 210098China Centre of Excellence in Water resources Engineering University of Engineering and TechnologyLahore 54890Pakistan Department of Agricultural Engineering Faculty of CivilAgricultural and Mining EngineeringUniversity of Engineering and TechnologyPeshawar 25120Pakistan

Climate and land use changes have a significant impact on the runoff generation process in urban environments, and these effects could get worse in the future. The combined contributions of these changes have increased the risk of ***, there is a need for integrated modeling to better understand the runoff variability, especially in small urban catchments. To quantify and separate the effects of land-use changes and climate change on the hydrological response of urban catchments with a distributed hydrological model(Storm Water Management Model, SWMM), this study introduces a new integrated approach based on the Machine Learning based land use change modeler and climate change scenarios under *** on supervised classification and land use change model analysis, accumulated impervious area increase from 22%(in2023) to 33%(in 2060) was observed in the study area. Furthermore, integrating this projected increase in imperviousness with future climate change into SWMM by considering three different scenarios i.e., S1(Climate Change), S2(Combined Land Use and Climate Change), and S3(Land use Change) resulted that climate change could cause an increase in runoff from 13.2% to18.3% in peak runoff and the contribution of land use could range from 9.1% to 18.6%. Similarly, in response to the coupled effects of climate and land-use change, the runoff would likely change from 24.53% to 39.66%. Conclusively, the study showed that despite climate change, intensive urban development by the substitution of impervious surfaces could also have a severe impact on the microclimate and hydrology of small catchments. Lastly, this study could provide a way forward for the future planning and management of water resources in small catchments which could be extended to larger catchments.

关键词： Climate change Land-use modeling runoff simulation Percent Imperviousness TerrSet

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Enhancing PDF Malware Detection through Logistic Model Trees

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Computers, Materials & Continua 2024年第3期78卷 3645-3663页

作者： muhammad Binsawad Department of Information Systems King Abdulaziz UniversityP.O.Box 80217Jeddah21589Saudi Arabia

Malware is an ever-present and dynamic threat to networks and computer systems in cybersecurity,and because of its complexity and evasiveness,it is challenging to identify using traditional signature-based detection *** study article discusses the growing danger to cybersecurity that malware hidden in PDF files poses,highlighting the shortcomings of conventional detection techniques and the difficulties presented by adversarial *** article presents a new method that improves PDF virus detection by using document analysis and a Logistic Model *** a dataset from the Canadian Institute for Cybersecurity,a comparative analysis is carried out with well-known machine learning models,such as Credal Decision Tree,Naïve Bayes,Average One Dependency Estimator,Locally Weighted Learning,and Stochastic Gradient *** traditional structural and JavaScript-centric PDF analysis,the research makes a substantial contribution to the area by boosting precision and resilience in malware *** use of Logistic Model Tree,a thorough feature selection approach,and increased focus on PDF file attributes all contribute to the efficiency of PDF virus *** paper emphasizes Logistic Model Tree’s critical role in tackling increasing cybersecurity threats and proposes a viable answer to practical issues in the *** results reveal that the Logistic Model Tree is superior,with improved accuracy of 97.46%when compared to benchmark models,demonstrating its usefulness in addressing the ever-changing threat landscape.

关键词： Malware detection PDF files logistic model tree feature selection cybersecurity

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Progress in electrocatalytic nitrate reduction for green energy:Catalyst engineering,mechanisms,and techno-economic feasibility

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Journal of Energy Chemistry 2024年第8期95卷 380-406,I0009页

作者： Hafiz muhammad Adeel Sharif Hafiz muhammad Farooq Khan Sadeeq Ullah Yuwei Wang muhammad Ahmad Bo Yang Changping Li muhammad Bilal Asif research Center for Eco-Environmental Engineering Dongguan University of TechnologyDongguan 523808GuangdongChina College of Chemistry and Engineering Shenzhen UniversityShenzhen 518060GuangdongChina FMH College of Medicine and Dentistry LahorePakistan School of Environment and Civil Engineering Research Center for Eco-Environment EngineeringDongguan University of TechnologyDongguan 523106GuangdongChina Advanced Membranes and Porous Materials Center(AMPMC) Physical Sciences and Engineering(PSE)King Abdullah University of Science and Technology(KAUST)Thuwal 23955Saudi Arabia

Ammonia(NH_(3))is an irreplaceable chemical that has been widely demanded to keep the sustainable development of modern ***,its industrial production consumes a huge amount of energy and releases extraordinary greenhouse gases(GHGs),leading to various environmental *** the green production of ammonia is a great challenge,which has been extensively pursued in the last *** this review,the most promising strategy,electrochemical nitrate reduction reaction(e-NO_(3)rr),is comprehensively investigated to give a complete understanding of its development and mechanism and provide guidance for future ***,owing to the complex reactions and limited selectivity,a comprehensive understanding of the mechanisms is crucial to further development and ***,NO_(3)^(-)rr is a promising strategy for simultaneous water treatment and NH_(3)production.A detailed overview of the recent progress in NO_(3)^(-)rr for NH_(3)production with nontransition and transition metal based electrocatalysts is *** addition,critical advanced techniques,future challenges,and prospects are discussed to guide future research on transition metal-based catalysts for commercial NH_(3)synthesis by NO_(3)^(-)reduction.

关键词： Nitrate reduction Electrolysis Pollution to solution Transition metal catalysts Ammonia synthesis Green energy

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Detection of real-Time Distributed Denial-of-Service (DDoS) Attacks on Internet of Things (IoT) Networks Using Machine Learning Algorithms

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Computers, Materials & Continua 2024年第8期80卷 2139-2159页

作者： Zaed Mahdi Nada Abdalhussien Naba Mahmood rana zaki Information Technology Center University of TechnologyBaghdad00964Iraq Continuous Education Center University of TechnologyBaghdad00964Iraq Computer Science Department University of TechnologyBaghdad00964Iraq

The primary concern of modern technology is cyber attacks targeting the Internet of *** it is one of the most widely used networks today and vulnerable to ***-time threats pose with modern cyber attacks that pose a great danger to the Internet of Things(IoT)networks,as devices can be monitored or service isolated from them and affect users in one way or *** Internet of Things networks is an important matter,as it requires the use of modern technologies and methods,and real and up-to-date data to design and train systems to keep pace with the modernity that attackers use to confront these *** of the most common types of attacks against IoT devices is Distributed Denial-of-Service(DDoS)*** paper makes a unique contribution that differs from existing studies,in that we use recent data that contains real traffic and real attacks on IoT *** a hybrid method for selecting relevant features,And also how to choose highly efficient *** gives the model a high ability to detect distributed denial-of-service *** model proposed is based on a two-stage process:selecting essential features and constructing a detection model using the K-neighbors algorithm with two classifier algorithms logistic regression and Stochastic Gradient Descent classifier(SGD),combining these classifiers through ensemble machine learning(stacking),and optimizing parameters through Grid Search-CV to enhance system *** were conducted to evaluate the effectiveness of the proposed model using the CIC-IoT2023 and CIC-DDoS2019 *** evaluation demonstrated the potential of our model in robust intrusion detection in IoT networks,achieving an accuracy of 99.965%and a detection time of 0.20 s for the CIC-IoT2023 dataset,and 99.968%accuracy with a detection time of 0.23 s for the CIC-DDoS 2019 ***,a comparative analysis with recent related works highlighted the superiority of our methodology in in

关键词： DDoS Service networks

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Consequences of rényi entropy on the thermal geometries and Hawking evaporation of topological dyonic dilaton black hole

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Communications in Theoretical Physics 2024年第2期76卷 102-110页

作者： muhammad Yasir Xia Tiecheng muhammad Usman Shahid Chaudhary Department of Mathematics Shanghai University and Newtouch Center for Mathematics of Shanghai UniversityShanghai200444China Department of Natural Sciences and Humanities University of Engineering and Technology LahoreNew CampusPakistan

The thermodynamics of black holes(BHs)has had a profound impact on theoretical physics,providing insight into the nature of gravity,the quantum structure of spacetime and the fundamental laws governing the *** this study,we investigate thermal geometries and Hawking evaporation of the recently proposed topological dyonic dilaton BH in anti-de Sitter(Ad S)*** consider rényi entropy and obtain the relations for pressure,heat capacity and Gibbs free energy and observe that the rényi parameter and dilaton field play a vital role in the phase transition and stability of the ***,we use Weinhold,ruppeiner and Hendi Panahiyah Eslam Momennia models to evaluate the scalar curvature of the BH and find out that the divergence points of the scalar curvature coincides with the zero of specific ***,using Stefan–Boltzmann law,we determine that the BH without a dilaton field evaporates far more quickly compared to the dilaton BH in Ad S space.

关键词： topological dyonic dilaton black hole phase transition thermal geometry Hawking evaporation

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