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Correlation between the skull base fracture and the incidence of intracranial hemorrhage in patients w让h traumatic brain injury

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Chinese Journal of Traumatology 2019年第5期22卷 286-289页

作者： Ahmad Faried Danny Halim Ingrid Ayke Widjaya Rendy Febrian Badri Syailendra Fii sulaiman muhammad Z.Arifin Department of Neurosurgery Faculty of MedicineUniversitas PadjadjaranDr.Hasan Sadikin HospitalBandungIndonesia Bandung Injury Research Unit Faculty of MedicineUniversitas PadjadjaranBandungIndonesia

Purpose:A head injury(HI)may cause a skull fracture,which may or may not be associated with injury to the *** essence,a skull base fracture(SBF)is a linear fracture at the base of the *** of consciousness and Glasgow coma score(GCS)may vary depending on an associated intracranial *** pathomechanism is believed to be caused by high energy impact directly to the mastoid and supraorbital bone or indirectly from the cranial *** of this study is to define the correlation between SBF and intracranial hemorrhage(ICH)in patients with ***:Analysis of data obtained from a retrospective review of medical records and from a systematized database pertaining to diagnostic criteria of SBF patients based only on clinical symptoms associated with ICH caused by HI treated in the Department of Neurosurgery at *** Sadikin Hospital,Bandung,Indonesia from January 1,2012 to December 31,*** exclusion criteria in eluded age less than 15 years and no head computed tomography(CT)scan examination ***:A total of 9006 patients were in eluded into this study in which they were divided into 3 groups:group 1,HI with no ICH;group 2,HI with single ICH and group 3,HI with multiple *** all the SBF cases,SBF at anterior fossa accounted for 69.40%of them,which were mostly accompanied with mild HI(64.70%).Severity of HI and site of SBF correlated with the existence of traumatic brain lesions on CT scan,thus these factors were able to predict whether there were traumatic brain lesions or *** of the patients with epidural hemorrhage(EDH)has single traumatic lesion on CT scan,whereas most of the patients with cerebral contusion(CC)has multiple traumatic lesions on CT *** patients with both traumatic brain injury and SBF,most of the patients with anterior fossa SBF has EDH;whereas most of the patients with middle fossa SBF were accompanied with *** was not required for most of the patients with ***:SBFs were strongly corre

关键词： Skull base fracture Intracranial hemorrhage Traumatic brain injury

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Discovery of Simple Sequence Repeat Markers through Transcriptome Analysis of Baccaurea motleyana

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Journal of Food Science and Engineering 2020年第2期10卷 33-46页

作者： Khairun Hisam Nasir muhammad Fairuz Mohd Yusof Mohd Shahril firdaus Abdul Razak Siti NorsaidahIbrahim Mira Farzana Mohamad Moktar Khadijah Awang Mohd Shukri Mat Ali Centre for Molecular Marker Discovery and Validation(CMDV) Agri-Omic dan BioinformaticsBiotechnology and Nanotechnology Research CentreMalaysian Agricultural Research and Development Institute(MARDI)Serdang 43400SelangorMalaysia Industrial Crop Research Centre Malaysian Agricultural Research and Development Institute(MARDI)Serdang 43400SelangorMalaysia Horticulture Research Centre Malaysian Agricultural Research and Development Institute(MARDI)Serdang 43400SelangorMalaysia

Baccaurea motleyana(rambai)is underutilized fruits that are native to Malaysia,Indonesia and *** this study,a total of 54,779 unigenes identified from rambai transcriptome were used for simple sequence repeat(SSR)analysis by MIcroSAtellite(MISA).A total of 20,420 SSRs were found to be distributed within 37.27%of the total number of *** repeats represented the main type,accounting for 64.04%,followed by trinucleotide repeats(20.28%)and dinucleotide repeats(19.94%).Gene annotation to seven databases has a success ratio of 68.53%(National Center for Biotechnology Information(NCBI)protein sequences),53.68%(NCBI nucleotide sequences),27.43%(Kyoto Encyclopedia of Genes and Genome Ortholog),56.0%(SwissProt),52.44%(Protein family),53.99%(Gene Ontology)and 26.44%(Kluster of Orthologous Group).Further rambai SSRs were randomly selected and validated to ***(rambai),***(tampoi),***(jentik-jentik),***(pupor)and ***(setambun).

关键词： Baccaurea SSR transcriptome gene annotation and SSR validation

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Development of Starfruit Simple Sequence Repeat (SSR) Using Next Generation Sequencing

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Journal of Food Science and Engineering 2019年第3期9卷 95-121页

作者： Khairun Hisam Nasir muhammad Fairuz Mohd Yusof Mohd Shahril firdaus Siti Zainab Jantan Mira Farzana Mohamad Moktar Siti Norsaidah Ibrahim Noor Baiti Abdul Aziz Joanna Cho Lee Ying Centre for Molecular Marker Discovery and Validation (CMDV) Agri-Omic dan Bioinformatics Biotechnology and Nanotechnology Research Centre Malaysian Agricultural Research and Development Institute (MARDI) 43400 Serdang Selangor Malaysia Horticulture Research Centre Headquarters Malaysian Agricultural Research and Development Institute (MARDI) 43400 Serdang Selangor Malaysia

Starfruit (Averrhoa carambola L.) is an important fruit for Malaysian export and great attention has been made to improve starfruit fruit quality at Malaysian Agricultural Research and Development Institute (MARDI). The current study used next generation sequencing (NGS) technologies to develop starfruit simple sequence repeat (SSR) from 2 varieties namely B11 and B17 using Illumina HiSeq. The pre-processed reads were de novo assembled to generate approximately 75,000 and 74,000 scaffolds respectively. Total genome size for B11 and B17 were around 345 Mbp and 342 Mbp based on K-mer distribution analysis. In-silico microsatellite mining of each variety has identified more than 17,000 SSR in B11 and B17 respectively. Dinucleotides were the most abundant, accounting for more than 70% of all SSR and repeat motif GA (49%) was most common. A total of 239 SSR primer pairs were designed from contigs larger than 350 nucleotides and tested for amplification. The 30 polymorphic SSRs were used to DNA fingerprint of 12 starfruit hybrids. Polymorphism information content (PIC) ranged from 0.1411 to 0.6838, with an average of 0.3919. The Unweighted Pair-Group Method for Arithmetic Averages (UPGMA) dendrogram clustered 12 starfruit accessions into 2 groups.

关键词： Starfruit (Averrhoa carambola L.) next generation sequencing molecular marker simple sequence repeat

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Retained placenta: Do we have any option?

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World Journal of Obstetrics and Gynecology 2014年第3期3卷 124-129页

作者： Pei Shan Lim Nor Azlin Mohamed Ismail Nur Azurah Abd Ghani Nirmala Chandralega Kampan Aqmar Suraya sulaiman Beng Kwang Ng Kah Teik Chew Abdul Kadir Abdul Karim muhammad Abdul Jamil Mohd Yassin Department of Obstetrics and Gynecology Faculty of Medicine Universiti Kebangsaan Malaysia

Retained placenta is a known cause of post-partum haemorrhage and maternal mortality. A recent systemic review has confirmed that the incidence of retained placenta had increased all over the world, which is more common in developed countries. Failure of retroplacental myometrium contraction is the main cause of retained placenta. Maternal age greater than 35 years, grandmultipara, preterm labor, history of previous retained placenta, and caesarean section were the risk factors for retained placenta. Manual removal of the placenta has been the treatment of choice. Attempts had been made by clinician and researchers to find a safe, effective and reliable method to avoid the need for surgical intervention. The efficacy and safety of prostaglandin, nitroglycerin or acupuncture in the management of retained placenta are yet to be further evaluated. Nonetheless, till date only intraumbilical vein oxytocin has been studied extensively but with varied success. More randomized clinical trials are needed to address this issue. However, if immediate manual placenta removal service is unavailable, a trial of intra-umbilical vein oxytocin 100 IU at a totalvolume of at least 40 m L while preparing for transfer to a tertiary center or theatre may result in spontaneous expulsion of the placenta.

关键词：胎盘残留产科治疗方法临床分析

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