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ILSM:Incorporated Lightweight Security Model for Improving QOS in WSN

Computer Systems Science & Engineering 2023年第8期46卷 2471-2488页

作者： Ansar Munir Shah Mohammed Aljubayri muhammad faheem Khan Jarallah Alqahtani Mahmood ul Hassan Adel Sulaiman Asadullah Shaikh Insitute of Southern Punjab MultanPakistan College of Computer Science and Information Systems Najran UniversityNajranSaudi Arabia Department of Computer Skills Deanship of Preparatory YearNajran UniversityNajranSaudi Arabia

In the network field,Wireless Sensor Networks(WSN)contain prolonged attention due to afresh *** like health care,traffic,defense,and many more systems espoused the *** networks contain tiny sensor nodes containing embedded processors,TinyOS,memory,and power *** nodes are responsible for forwarding the data *** manage all these components,there is a need to select appropriate parameters which control the quality of service of *** sensor nodes are involved in transmitting vital information,and there is a need for secure and efficient routing to reach the quality of *** due to the high cost of the network,WSN components have limited resources to manage the *** is a need to design a lightweight solution that ensures the quality of service in *** this given manner,this study provides the quality of services in a wireless sensor network with a security *** incorporated hybrid lightweight security model is designed in which random waypoint mobility(RWM)model and grey wolf optimization(GWO)is used to enhance service quality and maintain security with efficient *** version 16 andNetwork Stimulator 2.35(NS2.35)are used in this research to evaluate the *** overall cost factor is reduced at 60%without the optimization technique and 90.90%reduced by using the optimization technique,which is assessed by calculating the signal-to-noise ratio,overall energy nodes,and communication overhead.

关键词： Wireless sensor networks quality of service random waypoint mobility model grey wolf optimization security

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A Machine Learning Approach for Expression Detection in Healthcare Monitoring Systems

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Computers, Materials & Continua 2021年第5期67卷 2123-2139页

作者： muhammad Kashif Ayyaz Hussain Asim Munir Abdul Basit siddiqui AaqifAfzaal Abbasi muhammad Aakif Arif Jamal Malik Fayez Eid Alazemi Oh-Young Song Department of Computer Science&Software Engineering International Islamic UniversityIslamabad44000Pakistan Department of Computer Science Quaid-i-Azam UniversityIslamabad44000Pakistan Department of Computer Science Capital University of Science&TechnologyIslamabad44000Pakistan Department of Software Engineering Foundation UniversityIslamabad44000Pakistan Department of Computer Science Abdul Wali Khan UniversityMardan23200Pakistan Department of Computer Science and Information Systems College of Business StudiesPAAET12062Kuwait Department of Software Sejong UniversitySeoul05006Korea

Expression detection plays a vital role to determine the patient’s condition in healthcare *** helps the monitoring teams to respond swiftly in case of *** to the lack of suitable methods,results are often compromised in an unconstrained environment because of pose,scale,occlusion and illumination variations in the image of the face of the patient.A novel patch-based multiple local binary patterns(LBP)feature extraction technique is proposed for analyzing human behavior using facial expression *** consists of three-patch[TPLBP]and four-patch LBPs[FPLBP]based feature engineering *** representation is encoded from local patch statistics using these *** and FPLBP capture information that is encoded to find likenesses between adjacent patches of pixels by using short bit strings contrary to pixel-based *** images are transformed into the frequency domain using a discrete cosine transform(DCT).Most discriminant features extracted from coded DCT images are combined to generate a feature *** vector machine(SVM),k-nearest neighbor(KNN),and Naïve Bayes(NB)are used for the classification of facial expressions using selected *** experimentation is performed to analyze human behavior by considering standard extended Cohn Kanade(CK+)and Oulu–CASIA *** demonstrate that the proposed methodology outperforms the other techniques used for comparison.

关键词： Detection expressions gestures analytics pain patch-based local binary descriptor discrete cosine transform healthcare

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Recent Insights into Signaling Responses to Cope Drought Stress in Rice

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Rice science 2022年第2期29卷 105-117页

作者： muhammad Mahran ASLAM muhammad Abdul Rehman RASHID Mohammad Aquil siddiqui muhammad Tahir KHAN Fozia FARHAT Shafquat YASMEEN Imtiaz Ahmad KHAN Shameem RAJA Fatima RASOOL Mahboob Ali SIAL ZHAO Yan Nuclear Institute of Agriculture Tandojam Sindh 70060Pakistan Department of Bioinformatics and Biotechnology Government College University FaisalabadFaisalabad 38000Pakistan Research Center for Perennial Rice Engineering and Technology in Yunnan School of AgricultureYunnan UniversityKunming 650205China Department of Botany Government College for Women UniversityFaisalabad 38000Pakistan National Center of Bioinformatics Quaid-i-Azam UniversityIslamabad 45320Pakistan State Key Laboratory of Crop Biology Shandong Key Laboratory of Crop BiologyCollege of AgronomyShandong Agricultural UniversityTai’an 271018China

Drought is one of the hot topics needing urgent attention in the current era of climate *** massively disturbs the rice growth and productivity and is becoming a serious *** drought avoidance strategies in rice include stomatal closure,cellular adaptation and changes in root ***,the endogenous plant hormones(abscisic acid and jasmonic acid)and reactive oxygen species have paramount importance in drought tolerance in *** drought tolerance induces modification in biochemical,molecular and physiological properties of *** the molecular level,expression of several transcription-factors is modulated which further determine the activation of drought responsive gene *** activated protein kinases and Ca signaling pathways initiate an array of signaling cascade for mediating the gene expression in ***,conventional breeding methods combined with modern emerging techniques such as genetic engineering,to improve rice drought tolerance were *** review provided recent insights into major regulatory factors against drought stress,signaling mechanisms and molecular engineering strategies(including conventional transgenic and recent genome editing approaches)to induce drought tolerance in rice.

关键词： drought stress rice signaling response regulatory factor

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Preliminary study of microstructure, mechanical properties and corrosion resistance of antibacterial Ti-15Zr-xCu alloy for dental application

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Journal of Materials Science & Technology 2020年第15期47卷 31-43页

作者： Sharafadeen Kunle Kolawole Wang Hai Shuyuan Zhang Ziqing Sun muhammad Ali siddiqui Ihsan Ullah Wei Song Frank Witte Ke Yang School of Materials Science and Engineering University of Science and Technology of ChinaHefei230026China Institute of Metal Research Chinese Academy of SciencesShenyang110016China Department of Prosthodontics Geriatric Dentistry and Craniomandibular DisordersAssmannshauser Strane 4-614197BerlinGermany Federal Polytechnic OffaP.M.B.420OffaKwara StateNigeria

Ti-15 Zr-xCu(3≤x≤7,wt.%) novel antibacterial and antibiofilm alloys with competitive mechanical properties,biological responses and corrosion resistance were designed and *** heat treatment on Ti-15 Zr-7 Cu(TZC-7 A),after holding for 2 h at slightly above their beta transus temperature(BTT) ensured their tensile strength(UTS),yield strength(YS) and hardness(HRV) were improved by31.2%,20% and 12.3% respectively compared to the control without Cu,Ti-15 Zr(T-15 ZA).Although the3 wt.% Cu alloy displayed the highest elongation(26%),the TZC-7 A alloy also possessed a good *** of evenly dispersed Ti2 Cu and Zr2 Cu Cu-rich intermetallic phases formed as interwoven and alternating lamellae within the α+β matrix as a result of Cu addition,as revealed by X-ray diffraction(XRD),scanning electron microscopy(SEM) and transmission electron microscopy(TEM).These greatly contributed to their strengthening and bactericidal *** 98% antibacterial effect against *** and *** have been imparted,coupled with excellent biofilm *** polarization curves showed that the TZC-7 A alloy possessed higher corrosion resistance than commercially pure titanium,cp-Ti;contact angle test revealed enhanced hydrophilicity;while confocal laser scanning microscopy(CLSM) and cell counting kit(CCK-8) assays also displayed drastically lowered bacterial adhesion rate with comparatively no *** attachment on all alloys was similar but the best spread was obtained on TZC-7 A after 24 *** developed alloy has good potential as an antibacterial implant material with combination of optimized properties.

关键词： Ti-Zr alloy Cu addition Antibacterial Mechanical properties Intermetallic phases

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Establishment of Embryogenic Cultures and Efficient Plant Regeneration System from Explants of Forced Softwood Shoots of Teak (Tectona grandis L.)

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Horticultural Plant Journal 2016年第5期2卷 293-300页

作者： muhammad Akram faheem Aftab Department of Botany University of the Punjab

The present study highlights an efficient plant regeneration system in teak(Tectona grandis L.) using forced softwood shoots as an initial plant material. Forced softwood shoots of teak were cut to prepare shoot tip, nodal and internodal explants and cultured on Murashige and Skoog(MS) medium + NAA(1, 3, 6, 10, and 15 μmol · L-1) or TDZ(0.001, 0.01, 0.1, 1, 4, 8, 10, 12 μmol · L-1) for callus induction. Such calluses were further grown on the same levels of TDZ or 0.4, 1, 4, 8, 10 μmol · L-1 BA + 1 μmol · L-1 IBA or GA3. Callus induction was the highest with4.55 cm3 callus volume and 5.75 g dry weight at 0.1 μmol · L-1 TDZ from shoot tips after 35 days. Embryogenic calluses were then shifted to 6, 8 or12 μmol · L-1 TDZ + 2 μmol · L-1 BA or IBA along with 5 mmol · L-1 ascorbic acid(AA) for shoot regeneration from embryogenic cultures. The highest embryogenesis(100%) with 36.4 globular and 5.5 heart-shaped embryo-like structures was obtained at 8 μmol · L-1 TDZ + 2 μmol · L-1 BA after 63 days. Such cultures when further maintained on the same medium up to 150 days resulted in 100% shoot regeneration with 16.4 mean *** were elongated up to 50 mm on agar medium + 8 μmol · L-1 BA + 1 μmol · L-1 GA3. An efficient rooting response(70%) was achieved having4.50 mean number and 49.10 mm root length at 8 μmol · L-1 IBA + 8 μmol · L-1 NAA + 0.1% activated charcoal after 36 days. Rooted shoots were acclimatized in glasshouse, achieving 56.6% plantlet survival.

关键词： teak ascorbic acid embryogenesis morphogenic-callus shoot regeneration thidiazuron

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Cancer models in preclinical research:A chronicle review of advancement in effective cancer research

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Animal Models and Experimental Medicine 2021年第2期4卷 87-103页

作者： Humna Sajjad Saiqa Imtiaz Tayyaba Noor Yusra Hasan siddiqui Anila Sajjad muhammad Zia Department of Biotechnology Quaid-i-Azam UniversityIslamabadPakistan

Cancer is a major stress for public well-being and is the most dreadful *** models used in the discovery of cancer treatment are continuously changing and extending toward advanced preclinical *** models are either naturally existing or artificially prepared experimental systems that show similar features with human tumors though the heterogeneous nature of the tumor is very *** choice of the most fitting model to best reflect the given tumor system is one of the real difficulties for cancer ***,vast studies have been conducted on the cancer models for developing a better understanding of cancer invasion,progression,and early *** models give an insight into cancer etiology,molecular basis,host tumor interaction,the role of microenvironment,and tumor heterogeneity in tumor *** models are also used to predict novel can-cer markers,targeted therapies,and are extremely helpful in drug *** this review,the potential of cancer models to be used as a platform for drug screening and therapeutic discoveries are *** none of the cancer models is regarded as ideal because each is associated with essential caveats that restraint its application yet by bridging the gap between preliminary cancer research and transla-tional ***,they promise a brighter future for cancer treatment.

关键词： cancer cell lines computational cancer models genetically engineered mouse models organoids patient-derived xenografts personalized medicine

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Comprehensive genetic screening reveals wide spectrum of genetic variants in monogenic forms of diabetes among Pakistani population

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World Journal of Diabetes 2021年第11期12卷 1957-1966页

作者： Ibrar Rafique Asif Mir Shajee siddiqui muhammad Arif Nadeem Saqib Asher Fawwad Luc Marchand muhammad Adnan muhammad Naeem Abdul Basit Constantin Polychronakos Department of Biological Sciences International Islamic UniversityIslamabad 44000Pakistan Departments of Pediatrics and Human Genetics McGill University Health Centre Research InstituteMontreal H4A 3J1Canada Research Development and Coordination Pakistan Health Research CouncilIslamabad 44000Pakistan Department of Medicine Pakistan Institute of Medical SciencesIslamabad 44000PakistanPakistan Department of Medical Laboratory Technology National Skills UniversityIslamabad44000Pakistan Department of Biochemistry Baqai Institute of Diabetology and EndocrinologyBaqai Medical UniversityKarachi 74600SindhPakistan PHRC Research Centre FJMUPakistan Health Research CouncilLahore 54000Pakistan Department of Biotechnology Quaid-I-Azam UniversityIslamabad 44000Pakistan Department of Medicine Baqai Institute of Diabetology and EndocrinologyBaqai Medical UniversityKarachi 74600SindhPakistan

BACKGROUND Monogenic forms of diabetes(MFD)are single gene *** diagnosis is challenging,and symptoms overlap with type 1 and type 2 *** To identify the genetic variants responsible for MFD in the Pakistani population and their *** A total of 184 patients suspected of having MFD were *** inclusion criterion was diabetes with onset below 25 years of *** demographic and clinical information were taken from the *** maturity-onset diabetes of the young(MODY)probability score was calculated,and glutamate decarboxylase ELISA was *** negative patients and features resembling MODY were selected(n=28)for exome sequencing to identify the pathogenic *** A total of eight missense novel or very low-frequency variants were identified in 7 *** variants were found in genes for MODY,***1A(c.169C>A,***57Met),KLF11(c.401G>C,***134Ala),and HNF1B(c.1058C>T,***353Leu).Five variants were found in genes other than the 14 known MODY genes,***6(c.919G>A,***307Lys),WFS1(c.478G>A,***160Lys)and WFS1(c.517G>A,***173Lys),RFX6(c.1212T>A,***404Gln)and ZBTB20(c.1049G>A,***350His).CONCLUSION The study showed wide spectrum of genetic variants potentially causing MFD in the Pakistani *** MODY genes prevalent in European population(GCK,HNF1A,and HNF4a)were not found to be common in our *** of novel variants will further help to understand the role of different genes causing the pathogenicity in MODY patient and their proper management and diagnosis.

关键词： MODY Diabetes Genetics Monogenic diabetes Monogenic forms of diabetes

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Infrared Spectroscopy-Based Chemometric Analysis for Lard Differentiation in Meat Samples

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Computers, Materials & Continua 2023年第5期75卷 2859-2871页

作者： muhammad Aadil siddiqui M.H.Md Khir Zaka Ullah Muath Al Hasan Abdul Saboor Saeed Ahmed Magsi Department of Electrical and Electronic Engineering Universiti Teknologi PetronasSeri Iskandar32610Malaysia College of Engineering Al Ain UniversityAl Ain64141United Arab Emirates High Performance Cloud Computing Centre(HPC) Universiti Teknologi PetronasSeri Iskandar32610Malaysia

One of the most pressing concerns for the consumer market is the detection of adulteration in meat products due to their *** rapid and accurate identification mechanism for lard adulteration in meat products is highly necessary,for developing a mechanism trusted by consumers and that can be used to make a definitive *** Transform Infrared Spectroscopy(FTIR)is used in this work to identify lard adulteration in cow,lamb,and chicken samples.A simplified extraction method was implied to obtain the lipids from pure and adulterated *** samples were obtained by mixing lard with chicken,lamb,and beef with different concentrations(10%–50%v/v).Principal component analysis(PCA)and partial least square(PLS)were used to develop a calibration model at 800–3500 cm^(−1).Three-dimension PCA was successfully used by dividing the spectrum in three regions to classify lard meat adulteration in chicken,lamb,and beef *** corresponding FTIR peaks for the lard have been observed at 1159.6,1743.4,2853.1,and 2922.5 cm−1,which differentiate chicken,lamb,and beef *** wavenumbers offer the highest determination coefficient R2 value of 0.846 and lowest root mean square error of calibration(RMSEC)and root mean square error prediction(RMSEP)with an accuracy of 84.6%.Even the tiniest fat adulteration up to 10%can be reliably discovered using this methodology.

关键词： Fourier transform infrared spectroscopy lard halal PCA PLS RMSEC RMSEP

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Presentation delay in breast cancer patients and its association with sociodemographic factors in North Pakistan

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Chinese Journal of Cancer Research 2015年第3期27卷 288-293页

作者： muhammad Aleem Khan Sheharyar Hanif Sundas Iqbal muhammad faheem Shahzad Sehrish Shafique muhammad Taha Khan Department of Nuclear Medicine Nuclear MedicineOncology and Radiotherapy Institute Department of Medicine Ziauddin Medical University Armed Forces Institute of Cardiology Department of Physiology Rawal Institute of Health Sciences Nuffield Brentwood Hospital

Background： There is strong evidence that delayed diagnosis of breast cancer is associated with poor survival. The objectives were to determine the frequency of breast cancer patients with delayed presentation, the reasons of delay and its association with different socio-demographic variables in our ***： We interviewed 315 histologically confirmed breast cancer patients. Delay was defined as more than 3 months from appearance of symptoms to the consultation from doctor. Questions were asked from each patient which could reflect their understanding about the disease and which could be the likely reasons for their delayed ***： A total of 39.01%（n=123） of patients presented late and out of those, 40.7% wasted time using alternative medicines; 25.2% were not having enough resources; 17.1% presented late due to painless lump; 10.6% felt shyness and 6.5% presented late due to other reasons. Higher age, negative family history, 〈8 school years of education and low to middle socio-economic status were significantly associated with delayed presentation（P〈0.05）. Education and socioeconomic status were two independent variables related to the delayed presentation after adjustment for others [odds ratios（OR） of 2.26, 2.29 and 95% confidence intervals（CI） was 1.25-4.10, 1.06-4.94 respectively].Conclusions： Significant percentage of women with breast cancer in North Pakistan is experiencing presentation delay due to their misconceptions about the disease. Coordinated efforts with public health department are needed to educate the focused groups and mitigating the barriers identified in the study. Long term impact will be reduced overall burden of the disease in the region.

关键词： Breast cancer delayed diagnosis survival

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Finite Element Analysis of Laterally Loaded Fin Monopiles for Offshore Wind Turbine Foundation in Plaxis 3D

Finite Element Analysis of Laterally Loaded Fin Monopiles fo...

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作者：瑞兹（Syed muhammad faheem Rizvi）东南大学

学位级别：硕士

The effort has been made in recent years to increase the generation of sustainable power energy,such as wind *** wind turbine industry expands quickly and wind turbines keep on growing in both size and ***,new construction sites are incorporated as large areas are required in order to construct the wind turbine *** means that onshore area will not fulfill the requirement and offshore wind farms are being built increasingly farther from the coast and in deeper *** offshore wind turbines are often placed at water depths of *** most effectively and efficient offshore foundation for wind turbines are *** monopiles foundation often have an embedded length of 20-35 m and a diameter of 4m-8 *** a brief outline of the current state-of-the-art of the wind energy industry and an explanation about the significance of monopiles on offshore wind industry,the specificities of their geotechnical design,specifically the lateral-load design of these piles,is *** interaction between the soil and pile is usually characterized by a load-displacement curve,to which several theories were established over the years and is the basis of current lateral-load design of offshore *** aim of this thesis is to evaluate and compared experimental results of laterally loaded large scale monopiles located in East China Sea with same parameter of finite element model（FEM）of Plaxis3D,which is characterized by its flexible behavior,used as foundations for offshore wind turbines in different layers of *** this thesis,a 3D analysis of nonlinear with an elastic plastic soil model,an elastic pile material and interface elements are used to model the pile and soil *** study involves an investigation of the laterally loaded hollow steel monopile piles with 2.8 m outer diameter,with its displacements,followed by an interpretation and validation of the results with the existing theoretical principles of soil mechanics

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