检索结果-南通市图书馆

Metabolite profiling and antidiabetic attributes of ultrasonicated leaf extracts of Conocarpus lancifolius

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2020年第8期10卷 353-360页

作者： Syed Ali Raza Ayoub rashid Chaudhary muhammad Waseem Mumtaz Ahmad Adnan Hamid Mukhtar muhammad tayyab Akhtar Department of Chemistry Government College UniversityLahore54000 Pakistan Department of Chemistry University of GujratGujrat Pakistan Institute of Industrial Biotechnology Government College UniversityLahore54000 Pakistan

Objective:To profile the secondary metabolites and to evaluate the antidiabetic potential of hydroethanolic leaf extracts of Conocarpus ***:The various hydroethanolic extracts of Conocarpus lancifolius leaf were prepared by ultrasonication assisted *** phenolic contents,flavonoid contents,antioxidant activity,α-glucosidase andα-amylase inhibitions of leaf extracts were *** metabolite profiling was accomplished by UHPLC-Q-TOF-MS/MS *** antidiabetic assessment of the most potent extract was carried out by measuring the hypoglycemic and hypolipidemic effect in the high fat diet-fed diabetic albino *** blood glucose level,haemoglobin,total cholesterol,high-density lipoproteins(HDL)and low-density lipoproteins(LDL)were ***:The 60%ethanolic extract exhibited the highest phenolic and flavonoid contents of(349.39±2.13)mg GAE/g dry extract and(116.95±2.34)mg RE/g dry extracts,respectively,and the highest DPPH scavenging activity with an IC50 value of(32.87±1.11)μg/*** IC50 values forα-glucosidase andα-amylase inhibitions were(38.64±0.93)μg/mL and(44.80±1.57)μg/mL,***-Q-TOF-MS/MS analysis confirmed the presence of gallic acid,ellagic acid,corilagin,kaempherol-3-O-rutinoside,caffeic acid derivative,isorhamnetin and galloyl derivatives in the 60%ethanolic *** extract at a dose of 450 mg/kg body weight reduced blood glucose level,total cholesterol,LDL and HDL,and increased haemoglobin in alloxan-induced diabetic mice,Conclusions:Conocarpus lancifolius leaves are proved as a good source of biologically functional metabolites and possess antidiabetic activity which may be further explored to treat diabetes.

关键词： Antioxidant Antidiabetic Conocarpus lancifolius Metabolite profiling Diabetic mice model

Data Analysis of Network Parameters for Secure Implementations of SDN-Based Firewall

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2023年第11期77卷 1575-1598页

作者： Rizwan Iqbal rashid Hussain Sheeraz Arif Nadia Mustaqim Ansari tayyab Ahmed Shaikh Department of Telecommunication Engineering Dawood University of Engineering&TechnologyKarachiPakistan Faculty of Engineering Sciences and Technology Hamdard UniversityKarachiPakistan Faculty of Information Technology Salim Habib UniversityKarachiPakistan Department of Electronic Engineering Dawood University of Engineering&TechnologyKarachiPakistan

Software-Defined Networking(SDN)is a new network technology that uses programming to complement the data plane with a control *** enable safe connection,however,numerous security challenges must be *** attacks have been one of the most prominent risks on the internet for decades,and they are now becoming challenging difficulties in SDN *** solve these challenges,we proposed a unique firewall application built on multiple levels of packet filtering to provide a flooding attack prevention system and a layer-based packet detection *** study offers a systematic strategy for wrapping up the examination of SDN *** Mininet simulator examines the effectiveness of SDN-based firewalls at various network *** fundamental network characteristics that specify how SDN should *** three main analytical measures of the network are jitter,response time,and *** regular operations,their behavior evaluates in the standard SDN conditions of Transmission Control Protocol(TCP)flooding and User Datagram Protocol(UDP)flooding with no SDN *** Orbit Ion Cannon(LOIC)is applied to launch attacks on the transmission by the allocated *** and MATLAB are used for the behavioral study to determine how sensitive the parameters are used in the SDN network and monitor the fluctuations of those parameters for different simulated scenarios.

关键词： Software defined networking firewall POX controller open v switch Mininet OpenFlow

Growth, Physiological and Molecular Responses of Cotton (Gossypium arboreum L.) under NaCl Stress

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Plant Sciences 2014年第5期5卷 605-614页

作者： Sameera Hassan muhammad Bilal Sarwar Sajjad Sadique Bushra rashid Beenish Aftab Bahaeldeen Babiker Mohamed tayyab Husnain Center of Excellence in Molecular Biology University of the Punjab Lahore Pakistan

Salinity is one of the most serious growth limiting factor, therefore, no longer being ignored. Although, cotton is fairly salt tolerant;its sensitivity at crop stand and yield is affected. This study is planned to identify the growth, physiological and molecular parameters in local cotton varieties FDH 171 and FDH 786 under NaCl stress. There was 100% seed germination but hypocotyl length was reduced at increasing level of NaCl. Plant height, fresh and dry biomass were reduced as the plants were subjected to increased stress of NaCl. Stomatal conductance, transpiration and photosynthetic rate and ionic imbalance were found to be reduced under the gradual increase in NaCl stress and affected the plant’s overall physiological processes. PCR product of AtNHX3 has been identified in stressed and non-stressed plants. Thus, the genotypes FDH 171 & FDH 786 were found tolerant to adoption of salt stress and could be used as a source in crop improvement.

关键词： Salt Stress Gossypium arboretum Cotton Gas Exchange Parameters Growth Analysis

National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第9期30卷 1018-1042页

作者： Faisal Saud Dar Zaigham Abbas Irfan Ahmed muhammad Atique Usman Iqbal Aujla muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider Syed Mujahid Hassan Adnan Abdul Jabbar Aman Nawaz Khan muhammad Shoaib Khan muhammad Yasir Khan Amer Latif Nasir Hassan Luck Ahmad Karim Malik Kamran rashid Sohail rashid Mohammad Salih Abdullah Saeed Amjad Salamat Ghias-un-Nabi tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed Department of Hepatopancreatic Biliary Surgery&Liver Transplant Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Hepatogastroenterology and Liver Transplantation Dr.Ziauddin University HospitalKarachi 75600SindhPakistan University of Aberdeen Aberdeen B243FXUnited Kingdom Department of Pathology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Gastroenterology&Hepatology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Radiology Aga Khan UniversityKarachi 74800Pakistan Department of Oncology Hameed Latif HospitalLahore 54000Pakistan Division of Hepatopancreatic Biliary Surgery&Liver Transplantation Shifa International HospitalIslamabad 44000Pakistan Department of Hepatopancreatic Biliary Surgery&Liver Transplant Shaikh Zayed Hospital and Post Graduate Medical InstituteLahore 54000Pakistan Department of Medicine Aga Khan University HospitalKarachi 74800Pakistan Department of Liver Transplant Pir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Medicine&Gastroenterology Lifecare Hospital and Research CentrePeshawar 25000Khyber PakhtunkhwaPakistan Department of Hepatopancreatobiliary&Liver Transplant Bahria International HospitalLahore 54000Pakistan Department of Surgery Hepatopancreatobiliary&Liver TransplantDow University of Health SciencesKarachi 74800Pakistan Department of Gastroenterology Hepatology&NutritionPir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Oncology Dr.Ziauddin HospitalKarachi 74800Pakistan Department of Radiology Rehman Medical InstitutePeshawar 25000Pakistan Army Liver Transplant Unit Pak Emirates Military HospitalRawalpindi 46000Pakistan Department of Gastroenterology Sindh Institute of Urology and TransplantationKarachi 75500Pakistan rashid Nursing Home and Cancer Clinic Rashid Nursing Home and Cancer ClinicRawalpindi 46000Pakistan Department of Gastroentero

A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the *** Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this *** effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these *** coordinated effort can minimise delays and give patients a chance for curative treatment and effective *** diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance *** cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for ***,histopathologic confirmation is not always required before *** ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for *** only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette *** patients with unresectable hCCA can be considered for liver *** chemotherapy should be offered to patients with a high risk of *** use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary *** with acute cholangitis can be drained with endoscopic or percutaneous biliary *** chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.

关键词： Hilar cholangiocarcinoma Bismuth-Corlette classification Memorial Sloan Kettering Cancer Centre Staging Preoperative biliary drainage Portal vein embolisation Surgical resection Hepatectomy