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Change in mean postoperative pain in patients undergoing tonsillectomy with cold water versus usual practice:A pragmatic trial

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 24-28页

作者： Haissan Iftikhar Nida Zahid Adan Zubair Mohammad Wasif Nabeel N.Baig Khadijah Abid muhammad ozair awan.muhammad sohail awan Department of Otolaryngology Queen Elizabeth HospitalBirminghamUK Department of Surgery Aga Khan University HospitalKarachiPakistan College of Physicians and Surgeons Higher Education CommissionKarachiPakistan Department of UGME Aga Khan UniversityKarachiPakistan

Introduction:Tonsillectomy is one of the most common procedures performed in *** are various methods to perform tonsillectomies(cold and hot).Thermal damage and inflammation of the surrounding tissue using monopolar cautery is said to point to increased pain whereas immediate cooling of the burnt area is thought to reduce pain owing to heat *** objective was to determine the difference in mean post‐tonsillectomy pain scores among patients irrigated with cold water(4℃)and in patients not irrigated with cold *** and Methods:A quasi‐experimental trial was conducted from January 2016 to December 2017 at a tertiary care *** tonsillectomies were carried out with monopolar cautery at a power of 20 *** either received cold water irrigation post tonsillectomy of the tonsillar bed(intervention arm)or no irrigation(control arm).The pain score was measured on Days 0,1,3,5,and *** scores were charted on a visual analog scale on the respective ***:Seventy‐eight patients were included in the *** mean age of our patients was 10.26(4.24)years old in the intervention arm,and 11.95(4.19)years old in the control *** was observed that the pain was significantly lower in patients with cold water irrigation of the tonsillar fossa on Days 1,3,5,and 7(p=0.001).There were no readmissions postprocedure and none of our patients developed any complications ***:In this trial,we report a reduced pain score at all days of observation in the intervention *** of the tonsillar fossa is a safe,cost-effective,and less technically demanding technique that could be employed to reduce postoperative *** studies with randomization,blinding and a larger sample size could further improve on our results.

关键词： cold water tonsillectomy monopoalr tonsillectomy postoperative pain tonsillectomy

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Zero group velocity longitudinal modes in an isotropic cylinder

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Acta Mechanica Sinica 2018年第3期34卷 475-481页

作者： Takasar Hussain Faiz Ahmad muhammad ozair Department of Mathematics COMSATS Institute of Information Technology School of Natural Sciences National University of Sciences and Technology

Zero group velocity （ZGV） modes are studied in an isotropic cylinder. The L （0, 2） mode behaves anomalously for the materials with a value of the bulk velocity ratio, to, in the range √2 〈 κ 〈 2.64 and normally otherwise. All higher modes, except the first few, have no ZGV point for all isotropic materials. This is explained analytically by finding the slope of phase velocity dispersion curves of modes first when the phase velocity equals κ and then at their initial state.

关键词： Isotropic cylinder Longitudinal modes Zerogroup velocity point

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Computational Investigation of Hand Foot Mouth Disease Dynamics with Fuzziness

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Computers, Materials & Continua 2023年第5期75卷 4175-4189页

作者： Dumitru Baleanu Fazal Dayan Nauman Ahmed muhammad Rafiq Ali Raza muhammad ozair Ahmad Department of Mathematics Cankaya UniversityBalgatAnkara06530Turkey Department of Medical Research China Medical UniversityTaichung406040Taiwan Department of Computer Science and Mathematics Lebanese American UniversityBeirutLebanon Department of Mathematics School of ScienceUniversity of Management and TechnologyLahore54000Pakistan Department of Mathematics and Statistics University of LahoreLahore54590Pakistan Department of Mathematics Faculty of Science and TechnologyUniversity of Central PunjabLahore54000Pakistan Near East University Mathematics Research CenterDepartment of MathematicsNear East Boulevard99138Nicosia/Mersin 10Turkey Department of Mathematics Govt.Maulana Zafar Ali Khan Graduate College WazirabadPunjab Higher Education Department(PHED)Lahore54000Pakistan

The first major outbreak of the severely complicated hand,foot and mouth disease(HFMD),primarily caused by enterovirus 71,was reported in Taiwan in *** surveillance is needed to assess the spread of *** parameters we use in mathematical models are usually classical mathematical parameters,called crisp parameters,which are taken for *** any biological or physical phenomenon is best explained by *** represent a realistic situation in any mathematical model,fuzzy parameters can be very *** articles have been published on how to control and prevent HFMD from the perspective of public health and statistical ***,few works use fuzzy theory in building models to *** this context,we examined anHFMD model with fuzzy parameters.A Non Standard Finite Difference(NSFD)scheme is developed to solve the *** developed technique retains essential properties such as positivity and dynamic *** simulations are presented to support the analytical *** convergence and consistency of the proposed method are also *** proposed method converges unconditionally while the many classical methods in the literature do not possess this *** this regard,our proposed method can be considered as a reliable tool for studying the dynamics of HFMD.

关键词： Hand foot mouth disease fuzzy parameters NSFD scheme convergence consistency

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Numerical Investigation of Malaria Disease Dynamics in Fuzzy Environment

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Computers, Materials & Continua 2023年第2期74卷 2345-2361页

作者： Fazal Dayan Dumitru Baleanu Nauman Ahmed Jan Awrejcewicz muhammad Rafiq Ali Raza muhammad ozair Ahmad Department of Mathematics School of ScienceUniversity of Management and TechnologyLahore54000Pakistan Department of Mathematics Cankaya UniversityBalgatAnkara06530Turkey Department of Medical Research China Medical UniversityTaichung40402Taiwan Institute of Space Sciences Magurele-Bucharest077125Romania Department of Mathematics and Statistics University of LahoreLahore54000Pakistan Department of Automation Biomechanics and MechatronicsLodz University of Technology1/15 Stefanowskiego St.90-924LodzPoland Department of Mathematics Faculty of Science&TechnologyUniversity of Central PunjabLahore54000Pakistan Department of Mathematics Govt.Maulana Zafar Ali Khan Graduate College WazirabadPunjab Higher Education Department(PHED)Lahore54000Pakistan

The application of fuzzy theory is vital in all scientific *** construction of mathematical models with fuzziness is little studied in the *** this in mind and for a better understanding of the disease,an SEIR model of malaria transmission with fuzziness is examined in this study by extending a classicalmodel ofmalaria *** parametersβandδ,being function of the malaria virus load,are considered fuzzy *** steady states and the reproduction number of the model are analyzed in fuzzy senses.A numerical technique is developed in a fuzzy environment to solve the studied model,which retains essential properties such as positivity and dynamic ***,numerical simulations are carried out to illustrate the analytical results of the developed *** most of the classical methods in the literature,the proposed approach converges unconditionally and can be considered a reliable tool for studying malaria disease dynamics.

关键词： SIER model fuzzy parameters malaria NSFD scheme stability

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Numerical Analysis for the Effect of Irresponsible Immigrants on HIV/AIDS Dynamics

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Intelligent Automation & Soft Computing 2023年第5期36卷 1479-1496页

作者： muhammad Tariq Ali Dumitru Baleanu muhammad Rafiq Jan Awrejcewicz Nauman Ahmed Ali Raza muhammad Sajid Iqbal muhammad ozair Ahmad Department of Mathematics Barani Institute of SciencesBurewalaPakistan Department of Mathematics Cankaya UniversityBalgatAnkara06530Turkey Department of Medical Research China Medical UniversityTaichung40402Taiwan Institute of Space Sciences Magurele-Bucharest077125Romania Department of Mathematics Faculty of SciencesUniversity of Central PunjabLahore54000Pakistan Department of Automation Biomechanics and MechatronicsLodz University of Technology1/15 Stefanowskiego St.90-924 LodzPoland Department of Mathematics and Statistics University of LahoreLahore54590Pakistan Department of Mathematics Govt.Maulana Zafar Ali Khan Graduate College WazirabadPunjab Higher Education Department(PHED)Lahore54000Pakistan H&BS MCSNational University of Science and Technology(NUST)H-12IslamabadHumayun RoadRawalpindi46000Pakistan

The human immunodeﬁciency viruses are two species of Lentivirus that infect *** time,they cause acquired immunodeﬁciency syndrome,a condition in which progressive immune system failure allows life-threatening opportunistic infections and cancers to *** immunodeﬁciency virus infection came from a type of chimpanzee in Central *** show that immunodeﬁciency viruses may have jumped from chimpanzees to humans as far back as the late *** decades,human immunodeﬁciency viruses slowly spread across Africa and later into other parts of the *** Susceptible-Infected-Recovered(SIR)models are signiﬁcant in studying disease *** this paper,we have studied the effect of irresponsible immigrants on HIV/AIDS dynamics by formulating and considering different ***,Runge Kutta,and a Non-standardﬁnite difference(NSFD)method are developed for the same *** experiments are performed at disease-free and endemic equilibria points at different time step sizes‘ℎ’.The results reveal that,unlike Euler and Runge Kutta,which fail for large time step sizes,the proposed Non-standardﬁnite difference(NSFD)method gives a convergence solution for any time step *** proposed numerical method is bounded,dynamically con-sistent,and preserves the positivity of the continuous solution,which are essential requirements when modeling a prevalent disease.

关键词： SIR model existence analysis numerical methods stability analysis

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Numerical Analysis of Novel Coronavirus (2019-nCov) Pandemic Model with Advection

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Computers, Materials & Continua 2021年第6期67卷 2933-2953页

作者： Shumaila Azam Nauman Ahmed Ali Raza muhammad Sajid Iqbal muhammad Rafiq Ilyas Khan Kottakkaran Sooppy Nisar muhammad ozair Ahmad Zafar Iqbal Department of Mathematics and Statistics The University of LahoreLahorePakistan Department of Mathematics National College of Business Administration and Economics LahorePakistan Faculty of Engineering University of Central Punjab Lahore Pakistan Faculty of Mathematics and Statistics Ton Duc Thang UniversityHo Chi Minh City72915Vietnam Department of Mathematics College of Arts and Science at Wadi AldawaserPrince Sattam Bin Abdulaziz University11991AlkharjKingdom of Saudi Arabia Department of Mathematics University of Management and TechnologyLahorePakistan

Recently,the world is facing the terror of the novel corona-virus,termed as *** health institutes and researchers are continuously striving to control this *** this article,the SEIAR(susceptible,exposed,infected,symptomatically infected,asymptomatically infected and recovered)infection model of COVID-19 with a constant rate of advection is studied for the disease propagation.A simple model of the disease is extended to an advection model by accommodating the advection process and some appropriate parameters in the *** continuous model is transposed into a discrete numerical model by discretizing the domains,*** analyze the disease dynamics,a structure preserving non-standard finite difference scheme is *** steady states of the continuous system are described i.e.,virus free steady state and virus existing steady *** results show that both the steady states of the numerical design coincide with the fixed points of the continuous SEIAR *** of the state variables is ensured by applying the M-matrix theory.A result for the positivity property is *** the proposed numerical design,two different types of the stability are *** stability and linear stability for the projected scheme is examined by applying some standard *** Neuman stability test is applied to ensure linear *** reproductive number is described and its pivotal role in stability analysis is also *** and convergence of the numerical model is also *** graphs are presented via computer simulations to prove the worth and efficiency of the quarantine factor is explored graphically,which is helpful in controlling the disease *** the end,the conclusion of the study is also rendered.

关键词： 2019-nCov infectious model with advection reproductive number stability analysis numerical graphs

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New Trends in Fuzzy Modeling Through Numerical Techniques

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Computers, Materials & Continua 2023年第3期74卷 6371-6388页

作者： M.M.Alqarni muhammad Rafiq Fazal Dayan Jan Awrejcewicz Nauman Ahmed Ali Raza muhammad ozair Ahmad Witold Pawłowski Emad E.Mahmoud Department of Mathematics College of SciencesKing Khalid UniversityAbha61413Saudi Arabia Department of Mathematics Faculty of Sciences and TechnologyUniversity of Central PunjabLahorePakistan Department of Mathematics School of ScienceUniversity of Management and TechnologyLahorePakistan Department of Automation Biomechanics and MechatronicsLodz University of Technology1/15 Stefanowskiego St.90-924LodzPoland Department of Mathematics and Statistics University of LahoreLahorePakistan Department of Mathematics Govt.Maulana Zafar Ali Khan Graduate College WazirabadPunjab Higher Education Department(PHED)Lahore54000Pakistan Institute of Machine Tools and Production Engineering Lodz University of TechnologyPoland Department of Mathematics College of ScienceTaif UniversityP.O.Box11099Taif21944Saudi Arabia

Amoebiasis is a parasitic intestinal infection caused by the highly pathogenic amoeba Entamoeba *** is spread through person-toperson contact or by eating or drinking food or water contaminated with *** transmission rate depends on the number of cysts present in the *** traditional models assumed a homogeneous and contradictory transmission with *** heterogeneity of its transmission rate is a significant factor when modeling disease *** heterogeneity of disease transmission can be described mathematically by introducing fuzzy *** this context,a fuzzy SEIR Amoebiasis disease model is considered in this *** equilibrium analysis and reproductive number are studied with *** numerical schemes forward Euler method and a nonstandard finite difference(NSFD)approach,are developed for the learned model,and the results of numerical simulations are *** numerical and simulation results reveal that the proposed NSFD method provides an adequate representation of the dynamics of the disease despite the uncertainty and ***,the obtained method generates plausible predictions that regulators can use to support decision-making to design and develop control strategies.

关键词： Epidemic model fuzzy parameters amoebiasis NSFD scheme convergence

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Modeling of Computer Virus Propagation with Fuzzy Parameters

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Computers, Materials & Continua 2023年第3期74卷 5663-5678页

作者： Reemah M.Alhebshi Nauman Ahmed Dumitru Baleanu Umbreen Fatima Fazal Dayan muhammad Rafiq Ali Raza muhammad ozair Ahmad Emad E.Mahmoud Computer Science Department Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddahSaudi Arabia Department of Mathematics and Statistics University of LahoreLahore54590Pakistan Department of Mathematics Cankaya UniversityBalgatAnkara06530Turkey Department of Medical Research China Medical UniversityTaichung406040TaiwanChina Institute of Space Sciences Magurele-Bucharest077125Romania Department of Computer Science University of LahoreLahore54590Pakistan Department of Mathematics School of ScienceUniversity of Management and TechnologyLahore54000Pakistan Department of Mathematics Faculty of Science and TechnologyUniversity of Central PunjabLahore54000Pakistan Department of Mathematics Near East University TRNCMersin10Turkey Department of Mathematics Government Maulana Zafar Ali Khan Graduate College WazirabadPunjab Higher Education Department(PHED)Lahore5400Pakistan Department of Mathematics and Statistics College of ScienceTaif UniversityP O Box11099Taif21944Saudi Arabia

Typically,a computer has infectivity as soon as it is *** is a reality that no antivirus programming can identify and eliminate all kinds of viruses,suggesting that infections would persevere on the *** understand the dynamics of the virus propagation in a better way,a computer virus spread model with fuzzy parameters is presented in this *** is assumed that all infected computers do not have the same contribution to the virus transmission process and each computer has a different degree of infectivity,which depends on the quantity of *** this,the parametersβandγbeing functions of the computer virus load,are considered fuzzy *** fuzzy theory helps us understand the spread of computer viruses more realistically as these parameters have fixed values in classical *** essential features of the model,like reproduction number and equilibrium analysis,are discussed in fuzzy ***,with fuzziness,two numerical methods,the forward Euler technique,and a nonstandard finite difference(NSFD)scheme,respectively,are developed and *** the evidence of the numerical simulations,the proposed NSFD method preserves the main features of the dynamic *** can be considered a reliable tool to predict such types of solutions.

关键词： SIR model fuzzy parameters computer virus NSFD scheme stability

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Immunohistochemical Expression of Biomarkers and Human Papilloma Virus Infection in Esophageal Squamous Cell Carcinoma Patients of Pakistan-HPV and Biomarkers in ESCC

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国际感染病学（电子版） 2019年第1期8卷 1-7页

作者： S.M.Adnan Ali Yumna Mirza M.ozair awan K.M.Inam Pal Zubair Ahmad Office of Academia and Research in Surgery Department of SurgeryAga Khan University Hospital Medical College Aga Khan University Hospital Section of General Surgery Department of SurgeryAga Khan University Hospital Section of Histopathology Department of Pathology and Laboratory MedicinesAga Khan University Hospital

Objective To determine HPV infection status and expression of p16, cyclooxygenase-2(COX-2), Cyclin D1 and epidermal growth factor receptor(EGFR) in ESCC patients of Pakistan. Methods 51 ESCC patients treated at Aga Khan University Hospital(AKUH) were included. HPV infection status was confirmed via PCR while the expression of the four biomarkers was determined using immunohistochemistry. The correlation of all markers with patient clinicopathological features as well as each other was analyzed. Results HPV infection status and p16 overexpression was found to be negative in all the patients while COX-2, Cyclin D1 and EGFR were overexpressed in 56.9%, 62.7% and 49.0% of the patients respectively. COX-2 showed a significant correlation with tumor invasion while EGFR was shown to be significantly correlated with histological grading and COX-2 expression. Conclusion COX-2 and EGFR can be used as prognostic markers. HPV does not seem to be a causative agent for ESCC in Pakistan.

关键词： COX-2 Cyclin D1 EGFR ESCC HPV

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潜伏期和染病期均具有传染性的媒介传染病模型的全局稳定性分析(英文)

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应用泛函分析学报 2012年第4期14卷 321-329页

作者： Abid Ali Lashari muhammad ozair Gul Zaman 李学志 Centre for Advanced Mathematics and Physics National University of Sciences and Technology H-12IslamabadPakistan Department of Mathematics University of Malakand Chakdara Dir(Lower) Khyber PukhtoonkhwaPakistan 信阳师范学院数学学院信阳464000

讨论潜伏期和染病期均具有传染性的媒介传染病模型.得到模型基本再生数的表达式,证明了当基本再生数小于1时,无病平衡点是全局渐近稳定的,此时疾病消亡;当基本再生数大于1时,无病平衡点是不稳定的,系统存在全局渐近稳定的地方病平衡点,... 详细信息

讨论潜伏期和染病期均具有传染性的媒介传染病模型.得到模型基本再生数的表达式,证明了当基本再生数小于1时,无病平衡点是全局渐近稳定的,此时疾病消亡;当基本再生数大于1时,无病平衡点是不稳定的,系统存在全局渐近稳定的地方病平衡点,此时,疾病将在人群中持续存在,数值模拟验证了理论结果.

关键词：媒介传染病模型平衡点全局稳定性

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