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Evaluating therapeutic potential of coriander seeds and leaves(Coriandrum sativum L.) to mitigate carbon tetrachloride-induced hepatotoxicity in rabbits

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Asian Pacific Journal of Tropical Medicine 2018年第3期11卷 209-213页

作者： muhammad jawad iqbal Masood Sadiq Butt Aamir Shehzad muhammad Asghar National Institute of Food Science & TechnologyFaculty of FoodNutrition and Home SciencesUniversity of AgricultureFaisalabadPakistan Department of Biochemistry Unirersity of AgricultureFaisalabadPakistan

Objective: To evaluate the hepatic and renal protective potential of coriander seeds and leaves using animal feed model. Methods: Coriander seeds-and leaves-based sauces were administrated to normal(Study Ⅰ) and carbon tetrachloride(2 mL/kg B.W.)-induced hepatotoxic rabbits(Study Ⅱ). Hepatic and renal biomarkers like aspartate aminotransferase,alanine aminotransferase. alkaline phosphatase, superoxide dismutase and catalase were measured. Results: Coriander leaves-based sauce exerted more decline(P<0.05) in serum aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase levels in the study Ⅱ as 18.32%. 19.91% and 21.24%, respectively. While, hepatic superoxide dismutase and catalase levels were raised significantly(P<0.05) in both studies. Renal parameters also depicted positive impact by the provision of developed sauces. Conclusions: Coriander seeds and leaves based sauces are effective in alleviating the hepato/renal toxicity. The hepatoprotective effect of coriander leaves is more pronounced as compared to coriander seeds.

关键词： Coriander seeds Coriander leaves Hepatoprotective potential Hepatotoxicity Rabbits

CASIA-Iris-Africa:A Large-scale African Iris Image Database

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Machine Intelligence Research 2024年第2期21卷 383-399页

作者： jawad muhammad Yunlong Wang Junxing Hu Kunbo Zhang Zhenan Sun School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China Center for Research on Intelligent Perception and Computing National Laboratory of Pattern RecognitionInstitute of AutomationChinese Academy of SciencesBeijing 100190China

Iris biometrics is a phenotypic biometric trait that has proven to be agnostic to human natural physiological *** on iris biometrics has progressed tremendously,partly due to publicly available iris *** databases have been available to researchers that address pressing iris biometric challenges such as constraint,mobile,multispectral,synthetics,long-distance,contact lenses,liveness detection,***,these databases mostly contain subjects of Caucasian and Asian docents with very few *** many investigative studies on racial bias in face biometrics,very few studies on iris biometrics have been published,mainly due to the lack of racially diverse large-scale databases containing sufficient iris samples of Africans in the public ***,most of these databases contain a relatively small number of subjects and labelled *** paper proposes a large-scale African database named Chinese Academy of Sciences Institute of Automation(CASIA)-Iris-Africa that can be used as a complementary database for the iris recognition community to mediate the effect of racial biases on *** database contains 28717 images of 1023 African subjects(2046 iris classes)with age,gender,and ethnicity attributes that can be useful in demographically sensitive studies of *** of specific application protocols are incorporated with the database to ensure the database’s variability and *** results of some open-source state-of-the-art(SOTA)algorithms on the database are presented,which will serve as baseline *** relatively poor performances of the baseline algorithms on the proposed database despite better performance on other databases prove that racial biases exist in these iris recognition algorithms.

关键词： African iris recognition racial bias iris image database biometrics iris recognition

Anti-hypercholesterolemic and anti-hyperglycaemic effects of conventional and supercritical extracts of black cumin(Nigella sativa)

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Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 1014-1022页

作者： muhammad jawad iqbal Masood Sadiq Butt Mir muhammad Nasir Qayyum Hafiz Ansar Rasul Suleria National Institute of Food Science and Technology Faculty of FoodNutrition and Home SciencesUniversity of AgricultureFaisalabadPakistan Department of Agriculture and Food Technology Karakoram International UniversityGilgit-BaltistanPakistan UQ Diamantina Institute Translational Research InstituteFaculty of MedicineThe University of Queensland37 Kent Street WoolloongabbaBrisbaneQLD 4102Australia Department of Food NutritionDietetics and HealthKansas State UniversityManhattanKS 66506USA

Objective: To explore the hypoglycaemic and hypocholesterolemic potential of conventional and supercritical extracts of black ***: Purposely, rat modelling was carried out for 2 months by designing three studies i.e. study Ⅰ(normal rats), study Ⅱ(hyperglycaemic rats) and study Ⅲ(hypercholesterolemic rats). Each study was further divided into three groups based on diet ***, functional diet(contained extract of black cumin prepared by using conventional solvent) and nutraceutical diet(contained extract of black cumin prepared by supercritical fluid extraction system).Results: During whole trial, an abating trend was observed in the level of serum cholesterol with maximum reduction(12.8%) in nutraceutical group of study Ⅲ. Low density lipoprotein and triglyceride level was also lowered maximum in study Ⅲ as17.1% and 11.6%, respectively. Whereas, highest decline in glucose level was in nutraceutical group of study Ⅱ as 11.2%.Conclusions: Inclusion of black cumin extracts in diet significantly lowers the occurrence of hyperglycaemia and hypercholesterolaemia. Furthermore, hypoglycaemic and hypocholesterolemic potential of nutraceutical diet is more prominent as compared to functional diet.

关键词： Black cumin Functional food Nutraceuticals Supercritical extract Hyperglycaemia Hypercholesterolaemia

Citrus peel extract and powder attenuate hypercholesterolemia and hyperglycemia using rodent experimental modeling

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Asian Pacific Journal of Tropical Biomedicine 2017年第10期7卷 870-880页

作者： Humaira Ashraf Masood Sadiq Butt muhammad jawad iqbal Hafiz Ansar Rasul Suleria National Institute of Food Science & Technology Faculty of FoodNutrition & Home SciencesUniversity of Agriculture UQ School of Medicine Translational Research InstituteThe University of Queensland Department of Food NutritionDietetics & HealthKansas State University

Objective: To investigate hypocholesterolemic and hypoglycemic potential of citrus peel extract and powder using rodent experimental ***: Considering the fact, rat feeding trial was carried out for a period of 56 d to access the prophylaxis of citrus peel flavonoids by employing normal(study Ⅰ),hyperglycemic(study Ⅱ) and hypercholesterolemic(study Ⅲ) rats. Each study was further divided into three groups to ensure the provision of selected diets, i.e.,control, functional and nutraceutical diets. Each study was further divided into three groups to ensure the provision of selected diets, i.e., control, functional and nutraceutical ***: Declining trend for total cholesterol was observed in all studies with maximum reduction(8.55%) in rat group fed on nutraceutical diet in study Ⅲ. Likewise, levels of low density lipoproteins and triglycerides reduced 11.39% and 7.89% respectively in hypercholesterolemic rats. Moreover, nutraceutical diet alleviated the sera glucose level by 8.96% in study Ⅱ.Conclusions: Conclusively, inclusion of citrus peel bioflavonoids in dietary therapies is a promising strategy to modulate lipidemic and glycemic attributes without imparting any deleterious effect on hematological parameters.

关键词： Functional foods Nutraceutical Citrus powder Hypercholesterolemia Hyperglycemia Efficacy study

Natural Convection and Irreversibility of Nanofluid Due to Inclined Magnetohydrodynamics(MHD)Filled in a Cavity with Y-Shape Heated Fin:FEM Computational

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1505-1519页

作者： Afraz Hussain Majeed Rashid Mahmood Sayed M.Eldin Imran Saddique S.Saleem muhammad jawad School of Energy and Power Engineering Jiangsu UniversityZhenjiang212013China Department of Mathematics Air UniversityIslamabad44000Pakistan Center of Research Faculty of EngineeringFuture University in EgyptNew Cairo11835Egypt Department of Mathematics University of Management and TechnologyLahore54770Pakistan Department of Mathematics University of SargodhaSargodha40100Pakistan Department of Mathematics College of ScienceKing Khalid UniversityAbha61413Saudi Arabia Faculty of Sciences The Superior UniversityLahore54000Pakistan

This study explains the entropy process of natural convective heating in the nanofluid-saturated cavity in a heated fin andmagnetic *** temperature is constant on the Y-shaped fin,insulating the topwall while the remaining walls remain *** walls are subject to impermeability and non-slip *** mathematical modeling of the problem is demonstrated by the continuity,momentum,and energy equations incorporating the inclined magnetic *** elucidating the flow characteristics Finite ElementMethod(FEM)is implemented using stable FE pair.A hybrid fine mesh is used for discretizing the *** and thermal plots concerning parameters are *** addition,a detailed discussion regarding generation energy by monitoring changes in magnetic,viscous,total,and thermal irreversibility is *** addition,line graphs are created for the u and v components of the velocity profile to predict the flow *** simulations assume the dimensionless representative of magnetic field Hartmann number Ha between 0 and 100 and a magnetic field inclination between 0 and 90 degrees.A constant 4% volume proportion of nanoparticles is employed throughout all scenarios.

关键词： Finite element method nanomaterials entropy MHD square cavity Y-fin

A novel medical image data protection scheme for smart healthcare system

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CAAI Transactions on Intelligence Technology 2024年第4期9卷 821-836页

作者： Mujeeb Ur Rehman Arslan Shafique muhammad Shahbaz Khan Maha Driss Wadii Boulila Yazeed Yasin Ghadi Suresh Babu Changalasetty Majed Alhaisoni jawad Ahmad School of Computer Science and Informatics Cyber Technology InstituteDe Montfort UniversityLeicesterUK Department of Biomedical Engineering University of GlasgowGlasgowUK School of Computing Engineering and the Built EnvironmentEdinburgh Napier UniversityEdinburghUK Robotics and Internet‐of‐Things Laboratory Prince Sultan UniversityRiyadhSaudi Arabia Department of Computer Science Al Ain UniversityAl AinUnited Arab Emirates Department of Computer Engineering College of Computer Science King Khalid UniversityAbhaSaudi Arabia Computer Sciences Department College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadhSaudi Arabia

The Internet of Multimedia Things(IoMT)refers to a network of interconnected multimedia devices that communicate with each other over the ***,smart healthcare has emerged as a significant application of the IoMT,particularly in the context of knowledge‐based learning *** healthcare systems leverage knowledge‐based learning to become more context‐aware,adaptable,and auditable while maintain-ing the ability to learn from historical *** smart healthcare systems,devices capture images,such as X‐rays,Magnetic Resonance *** security and integrity of these images are crucial for the databases used in knowledge‐based learning systems to foster structured decision‐making and enhance the learning abilities of ***,in knowledge‐driven systems,the storage and transmission of HD medical images exert a burden on the limited bandwidth of the communication channel,leading to data trans-mission *** address the security and latency concerns,this paper presents a lightweight medical image encryption scheme utilising bit‐plane decomposition and chaos *** results of the experiment yield entropy,energy,and correlation values of 7.999,0.0156,and 0.0001,*** validates the effectiveness of the encryption system proposed in this paper,which offers high‐quality encryption,a large key space,key sensitivity,and resistance to statistical attacks.

关键词： data analysis medical image processing security

Prevalence of post-traumatic stress disorder and depressive symptoms among civilians residing in armed conflict-affected regions:a systematic review and meta-analysis

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General Psychiatry 2024年第3期37卷 324-334页

作者： Syed Hassan Ahmed AabiaZakai Maha Zahi muhammad Youshay jawad Rui Fu Michael Chaiton Dow University of Health Sciences KarachiPakistan Department of Psychiatry and Behavioral Health Penn State College of MedicineHersheyPennsylvaniaUSA Dalla Lana School of Public Health University of TorontoTorontoOntarioCanada institute of Mental Health Policy Research The Center of Addiction and Mental HealthTorontoOntarioCanada

Background Globally,populations afflicted by armed conflict are known to have high rates of mental health *** This meta-analysis aims to estimate the prevalence of post-traumatic stress disorder(PTSD)and depressive symptoms among civilians residing in armed conflictaffected *** This meta-analysis was conducted in accordance with the Preferred Reporting Items forSystematic Reviews and Meta-Analyses.A literature search employing MEDLINE(R),Embase Classic+Embase,APA PsyclNFO,Ovid Healthstar,Journal@Ovid Full Text,Cochrane,PTSDpubs and CINAHL was conducted from inception until 19 March 2024 to identify relevant *** assessment was performed using the Joanna Briggs Institute Critical Appraisal Checklist for Prevalence Studies,and a Comprehensive Meta-Analysiswas usedto conduct the statistical *** The search yielded 38595 articles,of which 57 were considered eligible for *** included studies comprised data from 64596 *** estimated a prevalence of 23.70%(95%CI 19.50%to28.40%)forPTSD symptomsand 25.60%(95%Cl 20.70%to 31.10%)for depressive features among war-afflicted *** subgroup analysis based on time since the war and the country's economic status revealed the highest prevalence for both PTSD and depressive symptoms was present during the years of war and in low/*** The results of this study provide conclusive evidence of the detrimental impacts of armed conflict on mental health ***,it is crucial to emphasise the significance of both physical and mental health in the aftermath of war and take appropriate humanistic measures to overcome challenges in the management of psychiatric illnesses.

关键词： analysis stress armed

Multi-site Passivation of ZnO Metal Oxides via Biomolecules for Efficient and Highly Stable Organic Solar Cells

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Chinese Journal of Chemistry 2024年第14期42卷 1582-1592页

作者： Irfan Ismail Maria Khalil Xiaomei Gao Xingze Chen muhammad jawad Rong Huang Zhiyun Li Emmanuel Acheampong Tsiwah Wei-shi Li Qun Luo Chang-Qi Ma i-Lab&Printable Electronics Research Center Suzhou Institute of Nano-Tech and Nano-Bionics(SINANO)Chinese Academy of Sciences(CAS)SuzhouJiangsu215123 China University of Chinese Academy of Sciences(UCAS) Beijing100040 China School of Nano-Tech and Nano-Bionics University of Science and Technology of China(USTC)HefeiAnhui230027 China Shanghai Institute of Organic Chemistry(SIOC) Chinese Academy of Sciences(CAS)Shanghai200032 China Vacuum Interconnected Nanotech Workstation(Nano-X) SuzhouJiangsu215123 China

ZnO nanoparticles(nps)among metal oxide(MOs)are proven to be essential electron transporting layers(ETLs)applied in organic solar cells(OSCs).However,intrinsic defects,interfacial charge recombination,and catalytic behavior towards the active layer restrict the applications of ZnO nps for efficient and long-term stable *** commonly available biomolecule cytidine 5'-monophosphate(CMP-OH)with phosphonic acid,its salt cytidine 5'-monophosphate disodium salt(CMP-ONa)with a phosphate group as an anchoring group and conjugated terminal functional in both analogous molecules provide carrier transfer bridge at bottom interface of the active *** theoretical investigations and characterizations have discovered the multi-site coordination of CMP-OH towards acceptor molecules and ZnO *** dual-side alignment of CMP analogous molecules hinders interfacial charge recombination and enhances charge transfer potential at ***,PM6:L8-BO-based OSCs with modified ETL obtain 18.13%efficiency,12%higher than that of unmodified *** higher efficiency,CMP-OH-based OSC devices illustrate remarkably improved thermal stability for 500 h at 85℃with 72%of initial PCE and operation stability for 2000 h with 90.1%of initial *** work reveals the passivation mechanism of multi-anchoring groups towards MOs and single-functional groups towards the active layer to optimize the interface for efficient and highly stable OSCs.

关键词： Organic solar cells Nanoparticles Nucleotides Interfacial interactions Surface chemistry Multi-site passivation

Recent advances in the diagnosis of drug-induced liver injury

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World Journal of Hepatology 2024年第2期16卷 186-192页

作者： Taqwa Ahmed jawad Ahmad Department of Medicine Icahn School of Medicine at Mount SinaiNew YorkNY 10029United States Department of Recanati-Miller Transplantation Institute Icahn School of Medicine at Mount SinaiNew YorkNY 10029United States

Drug-induced liver injury(DILI)is a major problem in the United States,commonly leading to hospital *** DILI is difficult as it is a diagnosis of exclusion requiring a temporal relationship between drug exposure and liver injury and a thorough work up for other *** addition,DILI has a very variable clinical and histologic presentation that can mimic many different etiologies of liver *** scoring systems can assess the probability that a drug caused the liver injury but liver biopsy findings are not part of the criteria used in these *** review will address some of the recent updates to the scoring systems and the role of liver biopsy in the diagnosis of DILI.

关键词： Drug induced liver injury Liver biopsy Diagnosis RUCAM RECAM