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Use of health-related quality of life tools in hepatobiliary surgery

Hepatobiliary & Pancreatic Diseases International 2008年第2期7卷 135-137页

作者： muhammad Shafique Sajid Mawara iftikhar Jasmin Rimple Mirza Khurrum Baig Department of Surgery Worthing Hospital West Sussex BN11 2DH UK

BACKGROUND: The objective of this article is to review the literature and discuss the various tools used in hepatobiliary surgery for the measurement of health related quality of life (HR-QOL) and highlight various outcome variables that affect the HR-QOL among patients with common hepatobiliary disorders. DATA SOURCES: We reviewed HR-QOL articles published in the last 20 years on different hepatobiliary curative or palliative procedures in all languages. RESULTS: HR-QOL is a questionnaire tool which is utilized to assess the changes in the health status of patients after a hepatobiliary intervention. These surveys are of increasingly importance, as health care providers are challenged to justify treatment approaches and rationale for any surgical intervention. These HR-QOL tools are very helpful for the evaluation of subjective outcome of common hepatobiliary procedures like gastrointestinal quality of life index (GIQLI) for cholecystectomy, functional assessment in cancer therapy (FACT) for liver resection, short form 36 (SF-36) for liver transplantation, and quality of life questionnaire for patients with pancreatic cancer (QLQ-PAN). CONCLUSIONS: Use of validated and reliable health instruments in hepatobiliary surgery is directed at measuring the impact in a reproducible and valid fashion. Curative or palliative procedures should be offered to the patients of hepatobiliary disorders after the assessment by HR-QOL tools. Because the impairments of function that may occur after different operations vary considerably, an operation-specific assessment of HR-QOL for each type of surgical procedure is becoming an essential principle to follow in a successful healthcare system.

关键词： quality of life questionnaire hepatobiliary surgery hepatectomy

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Intelligent computing networks for nonlinear influenza-A epidemic model

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International Journal of Biomathematics 2023年第4期16卷 125-154页

作者： Nabeela Anwar muhammad Shoaib iftikhar Ahmad Shafaq Naz Adiqa Kausar Kiani muhammad Asif Zahoor Raja Department of Mathematics University of Gujrat Punjab 50700 Pakistan Department of Mathematics COMSATS University Islamabad Attock Campus Attock 43600 Pakistan Future Technology Research Center National Yunlin University of Science and Technology 123 UniversityRoad Section 3 DouliouYunlin 64002TaiwanR.O.C.

The differential equations having delays take paramount interest in the research community due to their fundamental role to interpret and analyze the mathematical models arising in biological *** study deals with the exploitation of knack of artificial intelligence-based computing paradigm for numerical treatment of the functional delay differential systems that portray the dynamics of the nonlinear influenza-A epidemic model(IA-EM)by implementation of neural network backpropagation with Levenberg-Marquardt scheme(NNBLMS).The nonlinear IA-EM represented four classes of the population dynamics including susceptible,exposed,infectious and recovered *** referenced datasets for NNBLMS are assembled by employing the Adams method for sufficient large number of scenarios of nonlinear IA-EM through the variation in the infection,turnover,disease associated death and recovery *** arbitrary selection of training,testing as well as validation samples of dataset are utilizing by designed NNBLMS to calculate the approximate numerical solutions of the nonlinear IA-EM develop a good agreement with the reference *** proficiency,reliability and accuracy of the designed NNBLMS are further substantiated via exhaustive simulations-based outcomes in terms of mean square error,regression index and error histogram studies.

关键词： Functional delay differential systems nonlinear influenza-A epidemic model Adams method neural networks Levenberg-Marquardt scheme intelligent computing regression analysis

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Identification of microRNAs in ecological model plant <i>Mimulus</i>

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Journal of Biophysical Chemistry 2011年第3期2卷 322-331页

作者： muhammad Younas khan Barozai muhammad Din iftikhar Ahmed Baloch Department of Botany University of Baluchistan Sariab Road Quetta. Pakistan

MicroRNAs (miRNAs) are small, non-coding and regulatory RNAs about 20 to 24 nucleotides long. Their conserved nature among the various organisms makes them a good source of new miRNAs discovery by comparative genomics approach. This study resulted in 34 miRNAs belonging to 21 families in ecological model plant Mimulus. All the miRNA families (mir 156, 157, 159, 160, 164, 172, 319, 393, 395, 397, 399, 400, 403, 417, 419, 472, 782, 854, 858, 867 and 2112) are found for the first time in Mimulus. The MIR-399 is found as precursor miRNA cluster with 4 mature sequences. All 34 miRNA precursors form stable minimum free energy stem loop structure as their orthologues form and the mature miRNAs reside in the stem portion of the stem loop structure. Twenty eight are from Mimulus guttatus and six miRNAs belong to Mimulus lewisii. Their targets consist of dihy-droflavonol-4-reductase, cycloidea-like protein, DNA-directed RNA polymerase II, maturase (matR) and transcription factors like;squamosa-promoter binding, MYB, palmate-like pentafoliata 1.

关键词： Keywords: Comparative Genomics MicroRNAs Mimulus

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荫蔽和微生物可在分子水平上调控植物激素以增强植物的耐旱性

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Journal of Plant Ecology 2022年第6期15卷 1107-1117页

作者： muhammad Ahsan Asghar Bushra Ahmad Ali Raza Bilal Adil Hafz Hassan Javed muhammad Umer Farooq Abuzar Ghafoor muhammad iftikhar Hussain Iram Shafq Hassan Karim Xin Sun Wenyu Yang Gábor Kocsy Junbo Du Department of Biological Resources Agricultural InstituteCentre for Agricultural ResearchELKHMartonvásárHungary College of Agronomy Sichuan Agricultural UniversityChengdu 611130China Department of Plant Breeding and Genetics University of AgricultureFaisalabad 38000PunjabPakistan College of Resource Sichuan Agricultural UniversityChengdu 611130China Department of Field Crops Faculty of AgricultureÇukurova UniversityAdana 01330Turkey Department of Plant Biology&Soil Science Faculty of BiologyUniversity of VigoCampus As Lagoas MarcosendeVigo 36310Spain State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Sichuan Agricultural UniversityChengduSichuan 611130China

植物在其生命周期内会受到一系列不利环境的影响。其中,干旱胁迫是限制农业生产力的重要因素之一。为了在逆境的环境中得以生存,植物进化出了识别环境胁迫严重性的机制。植物可通过多种方式调节激素活性,以减轻干旱带来的不良影响。受... 详细信息

植物在其生命周期内会受到一系列不利环境的影响。其中,干旱胁迫是限制农业生产力的重要因素之一。为了在逆境的环境中得以生存,植物进化出了识别环境胁迫严重性的机制。植物可通过多种方式调节激素活性,以减轻干旱带来的不良影响。受荫蔽和微生物调控,植株的抗旱性提高,产量损失减少。脱落酸、生长素和乙烯等植物激素,可调控多种代谢途径,在荫蔽和微生物介导的植株抗旱性增强过程中起着重要作用。如我们的调控模型所示,CLAVATA3/EMBRYOSURROUNDING REGION-RELATED 25多肽因其可影响ABA合成而在此过程中具有重要作用。

关键词：脱落酸 CLAVATA3/EMBRYOSURROUNDING REGION-RELATED 25 生长素植物生长促进根瘤菌乙烯

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Geochemistry and petrogenesis of the Paleoproterozoic orthogneisses and granitoids of the Banded Gneissic Complex,central Rajasthan,NW India:Implications for crustal reworking processes

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Acta Geochimica 2023年第2期42卷 373-386页

作者： iftikhar Ahmad T.P.Abdul Latheef M.E.A.Mondal Ismail S.Hamidullah Kamaal Parvez Department of Geology Aligarh Muslim UniversityAligarhU.P 202002India Department of Earth Sciences Indian Institute of Technology RoorkeeRoorkee 247667India

Granitoids and orthogneisses(1.7 Ga)from the northern part of the Banded Gneissic Complex(BGC-II domain),Aravalli Craton(NW India)are geochemically analyzed to understand the geodynamic condition and crustal evolution *** samples are metaluminous to peraluminous(molar A/CNK:0.74±2.12),and characterized by Eu-anomaly ranging from 0.17 to 1.06,Fe_(2)O_(3)^(T)/(Fe_(2)O_(3)^(T)+MgO)from 0.8 to 0.9 and high magmatic zircon saturation temperature(>830°C)which are the features suggestive of A-type granite *** discrimination diagrams classify the samples as post-collisional extensional A2-type *** characteristics along with trace element ratios[(Y/Nb)_(N)=0.15 to 4.33(avg.0.76),(Th/Nb)_(N)=4.63 to 255.47(avg.63.13),(Th/Ta)_(N)=1.37 to 9.84(avg.8.86),(Ce/Pb)_(N)=0.05 to 3.05(avg.1.43)]indicate that the rocks were derived from a plagioclase-rich and garnet-free crustal source under lowpressure ***,it is also proposed that tonalite-trondhjemite-granodiorite(TTG)rocks which occur dominantly in southern Rajasthan(BGC-I)are precursors and their partial melting led to the generation of the studied A-type granite *** studied samples also bear close geochemical similarity with A-type granites of similar age(1.7 Ga)near the Sakhun-Ladera region of northern *** studied A-type granites are believed to be coeval to similar aged A-type granites of the Khetri and Alwar sub-basins of the North Delhi Fold Belt(NDFB).They are comparable in age and magmatic history to recorded A-type magmatism in North America and parts of the Chinese *** large geographical extents of synchronous A-type granites are proposed to be related to the Columbia Supercontinent assembly(ca.1.7 Ga;postcollisional granites).Thus,based on the studied extensional granites,we surmise that BGC-II was part of the Columbia Supercontinent.

关键词： Banded Gneissic Complex(BGC II) Aravalli Craton A-type granites Orthogneisses Rifting of Columbia

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Overview of Strain Characterization in Relation to Serological and Molecular Detection of Citrus tristeza Closterovirus

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Phyton-International Journal of Experimental Botany 2021年第4期90卷 1063-1074页

作者： Yasir iftikhar Mazhar Abbas Mustansar Mubeen muhammad Zafar-ul-Hye Faheema Bakhtawar Sonum Bashir Ashara Sajid muhammad Asif Shabbir Department of Plant Pathology College of AgricultureUniversity of SargodhaSargodha40100Pakistan Institute of Horticultural Sciences University of Agriculture FaisalabadFaisalabad38000Pakistan State Key Laboratory of Agricultural Microbiology and Provincial Key Laboratory of Plant Pathology of Hubei Province College of Plant Science and TechnologyHuazhong Agricultural UniversityWuhan430070China Department of Soil Science Faculty of Agricultural Sciences and TechnologyBahauddin Zakariya UniversityMultan60800Pakistan

Tristeza is a devastating viral disease in all the citrus growing countries throughout the world and has killed millions of citrus trees in severely affected *** citrus species grafted on sour orange rootstock are affected by this ***,the sweet orange,grapefruit and lime trees grafted on sour orange exhibit severe symptoms like quick decline,vein clearing,pin holing,bark scaling and degeneration leading to variable *** expression of Citrus tristeza virus(CTV)in different hosts has been attributed to virus isolates which are from severe to *** serological and molecular assays have been deployed to differentiate the strains of *** tristeza virus is diversified towards its strains on the basis of biological,serological and molecular *** expression is due to genetic alteration and different molecular basis have now been adopted for strain *** review will give a brief idea about the different CTV isolates,their characterization based on nucleic acid and serological *** methods along with salient features for strain characterization has also been *** review will also open the new aspects towards formulation of management strategies through different detection techniques.

关键词： Citrus tristeza virus symptomology detection serology isolates and host rang

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Glinus lotoides ethanolic extract alleviates LPS-induced anxiety and depression-like behavior by modulating antioxidant and inflammatory biomarkers in rats

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Asian Pacific Journal of Tropical Biomedicine 2022年第2期12卷 78-86页

作者： Ambreen Mehmood Awan Wafa Majeed Faraza Javed Bilal Aslam Asra iftikhar Hafiza Arooj Kanwal Sobia Fiaz Institute of Physiology and Pharmacology University of AgricultureFaisalabadPakistan Department of Pharmacology Faculty of Pharmacythe Islamia University of BahawalpurBahawalpurPakistan Department of Pharmacy University of FaisalabadFaisalabadPakistan Department of Pharmacy University of AgricultureFaisalabadPakistan

Objective:To explore the protective role of Glinus lotoides ethanolic extract in a depression model through modulating oxidant/antioxidant enzyme system and inflammatory ***:Phytochemical constituents of Glinus lotoides ethanolic extract were evaluated qualitatively and quantitatively along with *** were divided into six *** normal control and the intoxicated groups received normal saline,and the standard group received imipramine,while the remaining groups received 100,300,and 500 mg/kg Glinus lotoides ethanolic *** groups received treatments for 14 ***(LPS)were then administered i.p.(0.83 mg/kg)to all groups except the normal control *** 24 h,anxiety and depression-like behaviors were evaluated by performing behavioral analysis(open field,tail suspension,forced swim,sucrose preference test),and determining total oxidant status,total antioxidant capacity,catalase,and biochemical parameters[malondialdehyde,glutathione,superoxide dismutase,tumor necrosis factor(TNF)-alpha and interleukin(IL)-6].Results:Phytochemical studies confirmed the presence of phenols and flavonoids and HPLC analysis showed the presence of gallic acid,quercetin,chlorogenic,and caffeic *** oxidant status was significantly decreased,while total antioxidant capacity was significantly increased in the Glinus lotoides ethanolic extract treated ***,Glinus lotoides ethanolic extract diminished malondialdehyde,IL-6,and TNF-alpha levels,while increasing superoxide dismutase,catalase,and glutathione ***:Glinus lotoides ethanolic crude extract shows significant antidepressant activity by modulating oxidative and biochemical parameters that supports its folkloric use in traditional systems of medicine.

关键词： Glinus lotoides Biochemical markers Depression Traditional medicine Nervous system Anxiety Antioxidant Inflammation

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Spectral Hole Burning via Kerr Nonlinearity

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Communications in Theoretical Physics 2015年第10期64卷 473-478页

作者： Anwar Ali khan M.S.Abdul Jabar M.Jalaluddin Bakht Amin Bacha iftikhar Ahmad Department of Physics University of Malakand

Spectral hole burning is investigated in an optical medium in the presence of Doppler broadening and Kerr nonlinearity. The Kerr nonlinearity generates coherent hole burning in the absorption spectrum. The higher order Kerr nonlinearity enhances the typical lamb dip of the hole. Normal dispersion in the hole burning region while Steep anomalous dispersion between the two hole burning regions also enhances with higher order Kerr effect. A large phase shift creates large delay or advancement in the pulse propagation while no distortion is observed in the pulse. These results provide significant steps to improve optical memory, telecom devices, preservation of information and image quality.

关键词： spectral hole burning Kerr nonlinearity Doppler br

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Considerations for gluten free foods-pearl and finger millet processing and market demand

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Grain & Oil Science and Technology 2023年第2期6卷 59-70页

作者： Manivannan Selladurai Manoj Kumar Pulivarthi Anu Suprabha Raj Mehreen iftikhar P.V.Vara Prasad Kaliramesh Siliveru Kansas State University Department of Grain Science and IndustryManhattan 66506KansasUSA Kansas State University Department of AgronomyManhattan 66506KansasUSA

The market demand for gluten free foods is increasing due to frequent incidences of celiac disease and increasing awareness on consumption of gluten free *** have become the major constituent of diet as they are gluten-free and also excellent sources of micro and macro nutrients such as vitamins,minerals,dietary fibers and phenolic *** various millets,the finger millet and the pearl millet are the two most important and common millet varieties grown ***,they are regarded as the staple foods of the poor and vulnerable populations,development of new products and improvements in their nutritional quality will aid in the general health of these *** of millets and production of variable gluten-free ready-to-eat and nutritional supplements has increased their market value in the recent ***,processing can also help in shelf-life extension of the millets with nutritional enrichment,expanding its markets to non-traditional millet *** this context,the present review is aimed to focus on the current processing methods to develop products from the two millet varieties that are gluten free and outline their nutritional benefits.

关键词： Pearl millet Finger millet Nutritional value Processing Market value

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A variable precision rough set approach to knowledge discovery in land cover classification

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International Journal of Digital Earth 2016年第12期9卷 1206-1223页

作者： iftikhar U.Sikder Department of Information System Cleveland State UniversityOHUSA Department of Electrical Engineering and Computer Science Cleveland State UniversityOHUSA

This paper presents a granular computing approach to spatial classification and prediction of land cover classes using rough set variable precision *** particular,it presents an approach to characterizing large spatially clustered data sets to discover knowledge in multi-source supervised *** evidential structure of spatial classification is founded on the notions of equivalence relations of rough set *** allows expressing spatial concepts in terms of approximation space wherein a decision class can be approximated through the partition of boundary *** paper also identifies how approximate reasoning can be introduced by using variable precision rough sets in the context of land cover *** rough set theory is applied to demonstrate an empirical application and the predictive performance is compared with popular baseline machine learning algorithms.A comparison shows that the predictive performance of the rough set rule induction is slightly higher than the decision tree and significantly outperforms the baseline models such as neural network,naïve Bayesian and support vector machine methods.

关键词： Rough set theory soft computing granular computing remote sensing approximate reasoning

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