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From Molecular Pathology of COVID-19 to Nigella Sativum as a Treatment Option:Scientific Based Evidence of Its Myth or Reality

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Chinese Journal of Integrative Medicine 2022年第1期28卷 88-95页

作者： muhammad Atif Farrah Naz Junaid Akhtar muhammad Imran Sidrah Saleem Javed Akram muhammad Imran muhammad ikram Ullah Department of Clinical Laboratory Sciences College of Applied Medical SciencesJouf UniversitySakaka(75471)Saudi Arabia Department of Microbiology Government College UniversityFaisalabad(38000)Pakistan Department of Microbiology University of Health SciencesLahore(54600)Pakistan Department of Allied Health Sciences Sargodha Medical CollegeUniversity of SargodhaSargodha(40100)Pakistan University of Health Sciences Lahore(54600)Pakistan University Institute of Diet and Nutritional Sciences Faculty of Allied Health SciencesThe University of LahoreLahore(54590)Pakistan

COVID-19 virus is a causative agent of viral pandemic in human beings which specifically targets respiratory system of humans and causes viral *** unusual viral pneumonia is rapidly spreading to all parts of the world,currently affecting about 105 million people with 2.3 million *** review described history,genomic characteristics,replication,and pathogenesis of COVID-19 with special emphasis on Nigella sativum(***)as a treatment *** seeds are historically and religiously used over the centuries,both for prevention and treatment of different *** review summarizes the potential role of *** seeds against COVID-19 infection at levels of in silico,cell lines and animal models.

关键词： coronavirus nCoV-19 COVID-19 Nigella sativum review

Cascade-exciton model analysis of mass dependence of pion-induced fission

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Chinese Physics C 2014年第7期38卷 92-96页

作者： muhammad ikram Shahzad Zafar Yasin Warda Iram Shahida Jabeen Physics Division PINSTECH P.O. Nilore Islamabad Pakistan Physics Department Islamia University Bahawalpur Pakistan Physics Department AJ&K University Muzaffarbad Pakistan

The cascade-exciton model has been used to observe the dependence of pion induced fission cross sections on the mass of the target. The analysis has been performed at energies 80 MeV, 100 MeV and 150 MeV for both the positive and negative pions. It has been shown that a single value of the ratio af/an can satisfactorily reproduce the experimental findings when compared with the available experimental data in the literature. The general trend of the fission cross sections with mass （fissility parameter） is seen to be low and slowly changing for the lighter nuclei, and it will steeply rise for the heavy nuclei.

关键词： cascade-exciton model pion-induced fission cross sections

Radionuclide concentrations in sand samples from riverbanks of Muzaffarabad,Azad Kashmir

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Nuclear Science and Techniques 2018年第7期29卷 103-115页

作者： Abdul Razzaq Khan muhammad Rafique Abdul Jabbar Saeed Ur Rahman muhammad ikram Shahzad muhammad Ejaiz Khan Mulaika Yasin Department of Physics University of Azad Jammu andKashmir MuzaffarbadAzad Kashmir 13100Pakistan Health Physics Division Pakistan Institute of NuclearScience and Engineering(PINSTECH)NiloreIslamabad 45650Pakistan Department of Medical Physics Nuclear MedicineOncologyand Radiotherapy InstituteIslamabadPakistan Physics Division Directorate of SciencePINSTECHP.O.NiloreIslamabad 45650Pakistan

This paper presents the results of a radiological risk assessment arising from the presence of naturally occurring radionuclides in sand samples from three riverbanks in *** mean values obtained for 232 Th,226 Ra,and 40 K were found to be 44.58 ± 3.34,48.25 ± 1.77,and 239.92 ± 22.73 Bq kg^(-1),*** assess the uniformity of exposure,the radium equivalent activity(Raeq) was calculated and was found to be130.47 ± 8.29 Bqkg^(-1).The current reported value for Raeqis lower than the maximum permissible value,that is,370 Bq kg^(-1),and equivalent to a gamma dose of1.5 m Svy^(-1).To investigate the possible contribution to health risks of alpha particle exposure,the radon exhalation rate(RER) from the sand samples was *** mean RER for all the samples was found to be335 m Bq m-^(2) h^(-1).About 43% of the samples were found to have an indoor excess lifetime cancer risk value slightly higher than recommended safety limit of 1,as proposed by the ICRP.A normalized parameter,the equivalent multiplicative factor,was defined and used to compare the current results with the findings of studies performed in other *** findings are relevant to both human health and future environmental radiation monitoring.

关键词：放射性核种样品克什米尔河岸风险评价调查结果 226Ra gamma

Photocatalysis vs adsorption by metal oxide nanoparticles

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Journal of Materials Science & Technology 2022年第36期131卷 122-166页

作者： Usman Qumar Jahan Zeb Hassan Rukhsar Ahmad Bhatti Ali Raza Ghazanfar Nazir Walid Nabgan muhammad ikram Solar Cell Applications Research Lab Department of PhysicsGovernment College University Lahore54000 PunjabPakistan Department of Physics University of Lahore(Chenab Campus)Adjacent Chenab BridgeGujrat50700 PunjabPakistan Department of Physics University of Sialkot(USKT)1-Km Main Daska RoadSialkot51040 PunjabPakistan Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea Departament d’Enginyeria Química Universitat Rovira i VirgiliAv Països Catalans 2643007 TarragonaSpain.

Background:Metal oxide(MO)nanomaterials and related nanocomposites have been extensively studied for their potential use in water *** of their controlled morphologies,texture qualities,variable surface chemistry,distinct crystalline nature,high stability,and tunable band edges,MO nanostructured materials are highly selective towards deleting organic contaminants and heavy metal ions via adsorption and semiconductor ***-enhanced photocatalysis has recently received increasing interest,mainly due to the ability of the metal to directly or indirectly degrade pollutants.A diverse selection of MOs,with titanium dioxide(Ti O2),zinc oxide(Zn O),iron oxides(IO),and tungsten(W),as well as graphene-MOs nanocomposites with variable structure,crystalline,and morphological properties,offers a powerful platform for the growth of effective ***:The current work discusses novel advancements and potential for the removal of adsorptive and photocatalytic degradation of organic compounds(phenolic,pesticide molecules,dyes,and so on)as well as heavy metal ions using semiconductor materials.A photocatalyst based on a MO-scheme heterostructure can manage the appropriate conduction band(CB)and valence band(VB)locations,securing considerable redox *** review should be of interest to the broad readership dealing with applied and fundamental aspects of water treatments and material *** strategies including surface modification,plasmonic enhancement,and metal cocatalysts have been introduced to enhance photocatalytic *** findings:The current article discussed the significantly utilized synthesis strategies and mechanism of heterojunction photocatalysts using a ***,adsorption sections guarantee that mercury,chromium,cadmium,arsenic,and lead-based ions are successfully removed from polluted water via the adsorption *** characteristics,such as concentration,coexisting ions,p H,and ki

关键词： Photocatalyst Adsorbate Metal Oxides Z-scheme Surface Modification Heterojunction Semiconductor heterostructures Nanoparticles

Response of tomato growth to continuous elevated CO_(2)concentration 2 under controlled environment

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International Journal of Agricultural and Biological Engineering 2022年第6期15卷 51-59页

作者： muhammad Akhlaq Chuan Zhang Haofang Yan Mingxiong Ou Wencheng Zhang Shaowei Liang Rana muhammad Adnan ikram School of Agricultural Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina Faculty of Agricultural Engineering and Technology PMAS-Arid Agriculture UniversityRawalpindi 46300Pakistan Research Center of Fluid Machinery Engineering and Technology Jiangsu UniversityZhenjiang 212013JiangsuChina State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering Nanjing Hydraulic Research InstituteNanjing 210029China College of Economics and Statistics Guangzhou UniversityGuangzhou 510006China

CO_(2)fumigation has been extensively used in greenhouses cultivation to enhance crop *** effects under the precise level of elevated CO_(2)(e[CO_(2)])on crop morphology,yield,and fruit quality remain largely elusive *** explore the response of plant growth to the continuous RCPs(Representative Concentration Pathways)projected CO_(2)concentration[CO_(2)],tomato(Hezuo 908)plants were grown under ambient CO_(2)(a[CO_(2)],462μmol/mol)and e[CO_(2)](550,700,850 and 1000μmol/mol):named as EC550,EC_(700),EC_(850),and EC_(1000),respectively,under uniform environmental condition for two planting *** growth of tomato plants(plant height,stem diameter,and leaf area index)was significantly enhanced under EC_(700)and showed a slightly negative response under EC_(850).The optimum yield was stimulated under EC_(700)by 74.05%and 55.91%,while maximum total dry weight(DW_(t))was enhanced under EC_(1000)by 58.23%and 39.78%during autumn-winter and spring-summer planting seasons,respectively,as compared to a[CO_(2)].The greatest yield and least DWt stimulated under EC_(700)for both seasons indicated that EC_(700)improved the ability of the tomato plants to translocate carbohydrates to *** water use efficiency related to yield(WUE_(y))was enhanced by 55.91-210.87%under EC_(700)compared to a[CO_(2)].The titratable acid(TA)was improved by 19.94%(EC_(700)),29.17%(EC_(850)),and 97.92%(EC_(1000)),and the lycopene(Lp)was increased by 2.22%(EC_(700))and reduced by 2.28%(EC_(1000)).Thus,the overall optimum impact on tomato growth was explored under EC_(700).Super e[CO_(2)]did not positively influence the tomato growth process and yield under adequate water and fertilizer *** present study results are beneficial for greenhouse crop production and might be used as a reference to validate the climate change influence modeling.

关键词： elevated CO_(2) tomato plant yield water use efficiency fruit quality

Homozygosity mapping of a consanguineous Pakistani family affected with oculocutaneous albinism to Tyrosinase gene

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International Journal of Ophthalmology(English edition) 2016年第5期9卷 794-796页

作者： muhammad Shakil muhammad ikram Ullah Shabbir Hussain Sabika Firasat Saqib Mahmood Haiba Kaul Department of Biochemistry University of Health Sciences Department of Biochemistry Faculty of Biological sciencesQuaid i Azam University Department of Animal Sciences Quaid i Azam University Department of Human Genetics and Molecular Biology University of Health Sciences

Dear Sir,Iam Haiba Kaul,from the Department of Biochemistry,University of Health Sciences,Lahore,Pakistan.I write to present a study of oculocutaneous albinism（OCA）in consanguineous Pakistani *** is a genetic defect... 详细信息

关键词： TYR Homozygosity mapping of a consanguineous Pakistani family affected with oculocutaneous albinism to Tyrosinase gene

Bioassay studies of cobalt (Ⅱ) complexes of modified diamine

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Frontiers of Chemistry in China 2011年第2期6卷 98-104页

作者： Saeed-UR-REHMAN muhammad ikram Sadia REHMAN Shah NAWAZ Institute of Chemical Sciences University of PeshawarPeshawar 25120Pakistan

Coordination compounds of modified diamine,the basic unit of which are ethylenediamine,with that of Co(Ⅱ)are *** modified diamines are ethylenediaceticacid(EDDA)and N,N,N,N-tetaraethylene-1,2-diamine(TEEDA).These diamines are characterized through ^(1)H-NMR,^(13)C-NMR,elemental analysis and IR ***(Ⅱ)complexes of these two ligands were prepared and characterized by physical measurements including elemental analysis,IR,UVVisible,magnetic susceptibilities and conductance *** activities are also carried out in order to investigate the biological activity upon *** were screened against four pathogenic bacteria like Escherichia coli,Pseudomonas aeroginosa,Klesbella pneumonia and Staphylococcus *** results showed significant enhancement in activities.

关键词： EDDA TEEDA cobalt complexes antibacterial studies

Does abnormal lending behavior increase bank riskiness?Evidence from Turkey

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Financial Innovation 2019年第1期5卷 630-644页

作者： Farrukh Shahzad Zeeshan Fareed Bushra Zulfiqar Umme Habiba muhammad ikram School of Economic and Business Administration Chongqing UniversityChongqingChina School of Business Huzhou UniversityHuzhou CityZhejiang ProvinceChina School of Economics Southwestern University of Finance and EconomicsChengduChina School of Finance Shanxi University of Finance and EconomicsTaiyuanShanxi ProvinceChina College of Economics and Management Nanjing University of Aeronautics and Astronautics NanjingChina

Purpose:This study empirically analyzes whether the rapid growth of loans and risktaking behavior during the expansion of loans affected non-performing loans(NPLs)and the solvency of financial institutions in the Turkish banking ***/methodology/approach:Using the GMM Generalized Method of Moments,this study used data on Turkish banks from 2011 to 2017 to test two hypotheses on the effects of loan growth on NPLs and ***:This study finds significant results for the effect of loan growth on NPLs and *** rose from the previous year’s loan growth,which tended to reduce *** limitations/implications:Due to selected research methods,the results may lack ***,future studies should test the propositions herein *** implications:The results indicate that careful allocation behavior is required when ***,these findings may be helpful to financial managers and decision ***/value:This study confirms the need to determine how to allocate loans during the loan boom periods.

关键词： Turkish banks Non-performing loans Loan growth Solvency GMM

Potential Inhibitory Effect of Vitamins Against COVID-19

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Computers, Materials & Continua 2021年第1期66卷 707-714页

作者： Kashaf Junaid Sumera Qasim Humaira Yasmeen Hasan Ejaz Abdullah Alsrhani muhammad ikram Ullah Fahad Ahmad Abdul Rehman Department of Clinical Laboratory Sciences College of Applied Medical SciencesJouf UniversitySakakaAl JoufSaudi Arabia College of Pharmacy Jouf UniversitySakakaAl JoufSaudi Arabia Department of Microbiology and Molecular Genetics The Women’s UniversityMultanPakistan Department of Computer Sciences Kinnaird College for WomenLahorePakistan Department of Microbiology and Molecular Genetics University of the PunjabLahorePakistan

Coronavirus disease 2019(COVID-19)is a current pandemic that has affected more than 195 countries *** this severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic,when treatment strategies are not yet clear and vaccines are not available,vitamins are an excellent choice to protect against this viral *** rationale behind this study was to examine the inhibitory effect of vitamins B,C,and D against the main protease of SARSCoV-2 and angiotensin-converting enzyme 2(ACE2),which have critical rolesin the immune *** docking,performed by using MOE-Dock of the Chemical Computing Group,was used to understand the *** vitamins all docked within the active sites of the Mpro(PDB ID:6LU7)and ACE2 receptor proteins(PDB ID:6VW1).Vitamins B and C delivered maximum energy scores against both targets,while vitamin D displayed a binding energy score of−7.9532 kcal/mol for M^(pro) and−7.9297 for *** efficiency of all three vitamins is higher than the binding energy score of chloroquine(−6.889 kcal/mol),which is now under clinical *** use of vitamins is beneficial,being immune system restorative,and they also act as anti-COVID *** the potential beneficial effects of vitamin B and C are revealed through docking studies,further clinical trials are required for the validation of these results.

关键词： SARS-CoV-2 vitamins docking antivirals chemical computing