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产业用纺织品 2006年第3期24卷 12-17页

作者： Pauquet J.R. Chan S.M. Roth M. mueller d. Gand. M. 陈淑萌火贤磊 Ciba Specialty Chemical公司

汽巴精细化工公司推出的新型添加剂(商品名C iba IRGATEC CR 76)不含过氧化物,在熔喷纺丝过程中对树脂提供可控性的降解,使产品具有优越的性能。该项技术不只适用于市场上的纺粘级原料,还能把纺粘或纺熔复合废料转换成高附加值的熔喷规... 详细信息

汽巴精细化工公司推出的新型添加剂(商品名C iba IRGATEC CR 76)不含过氧化物,在熔喷纺丝过程中对树脂提供可控性的降解,使产品具有优越的性能。该项技术不只适用于市场上的纺粘级原料,还能把纺粘或纺熔复合废料转换成高附加值的熔喷规格的树脂。该新型的添加剂属新一代的自由基生成剂,克服了目前过氧化物工艺的缺点。产品呈粒状,可安全稳定地用于生产和储存,减粘裂化作用在一般加工温度范围内非常有效,可以得到理想的相对分子质量分布较窄的树脂。用此技术所生产的熔喷非织造布及纺粘/熔喷非织造布(例如SMS)在静水压、透气性及机械性能上得到极大的改善。非织造布原料的灵活性是该新型工艺的主要优点,并能提供开发出独特非织造布的可能性。

关键词：熔喷非织造布聚丙烯树脂减粘裂化添加剂

Structure and.Function of TPC1 Vacuole SV Channel Gains Shape

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Molecular Plant 2018年第6期11卷 764-775页

作者： Rainer Hed.ich Thomas d. mueller d.rk Becker Irene Marten Institute for Molecular Plant Physiology and.Biophysics University of Wurzburg Julius-yon-Sachs Platz 2 97082 Wurzburg Germany

Plants and.animals in end.somes operate TPCI/SV-type cation channels. All plants harbor at least one TPC1 gene. Although the encod.d.SV channel was firstly d.scovered.in the plant vacuole membrane two d.cad.s ago, its biological function has remained.enigmatic. Recently, the structure of a plant TPC1/SV channel protein was d.termined. Insights into the 3d.topology has now guid.d.site-d.rected.mutation ap- proaches, enabling structure-function analyses of TPC1/SV channels to shed.new light on earlier find.ngs. Fou2 plants carrying a hyperactive mutant form of TPC1 d.velop wound.ng stress phenotypes. Recent stud.es with fou2 and.mutants that lack functional TPC1 have revealed.atypical features in local and.long-d.stance stress signaling, provid.ng new access to the previously mysterious biology of this vacuolar cation channel type in planta.

关键词： Ca^2+ sensors TPC1/SV channel vacuole membrane voltage voltage sensor

Salt Stress Triggers Phosphorylation of the Arabid.psis Vacuolar K＋ Channel TPK1 by Calcium-d.pend.nt Protein Kinases （Cd.Ks）

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Molecular Plant 2013年第4期6卷 1274-1289页

作者： And.eas Latz Norbert Mehlmer Simone Zapf Thomas d. mueller Bernhard.Wurzinger Barbara Pfister Ed.na Csaszar Rainer Hed.ich Markus Teige d.rk Becker d.partment of Molecular Plant Physiology and.Biophysics Julius-von-Sachs-lnstitute University of Wurzburg Julius-von-Sachs-Platz 2 D-97082 Wurzburg Germany d.partment of Biochemistry and.Cell Biology Max F. Perutz Laboratories University of Vienna Dr. Bohrgasse 9 A-1030 Vienna Austria Present ad.ress: d.partment of Biology I Botany Munich Center for Integrated Protein Science CiPSM Ludwig-Maximilians-Universitat Munchen D-82152 Planegg-Martinsried Germany College of Science King Saud University Riyadh 11451 Saudi Arabia

14-3-3 proteins play an important role in the regulation of many cellular processes. The Arabid.psis vacuolar two-pore K＋ channel 1 （TPK1） interacts with the 14-3-3 protein GRF6 （GF14-λ）. Upon phosphorylation of the putative bind.ng motif in the N-terminus of TPK1, GRF6 bind. to TPK1 and.activates the potassium channel. In ord.r to gain a d.eper und.rstand.ng of this 14-3-3-med.ated.signal transd.ction, we set out to id.ntify the respective kinases, which regulate the phosphorylation status of the 14-3-3 bind.ng motif in TPK1. Here, we report that the calcium-d.pend.nt protein kinases （Cd.Ks） can phosphorylate and.thereby activate the 14-3-3 bind.ng motif in TPK1. Focusing on the stress-activated.kinase CPK3, we visualized.d.rect and.specific interaction of TPK1 with the kinase at the tonoplast in vivo. In line with its proposed.role in K＋ homeostasis, TPK1 phosphorylation was found.to be ind.ced.by salt stress in planta, and.both cpk3 and.tpkl mutants d.splayed.salt-sensitive phenotypes. Molecular mod.ling of the TPK1-CPK3 interaction d.main provid.d.mechanistic insights into TPK1 stress-regulated.phosphorylation responses and.pinpointed.two arginine resid.es in the N-terminal 14-3-3 bind.ng motif in TPK1 critical for kinase interaction. Taken together, our stud.es provid. evid.nce for an essential role of the vacuolar potassium channel TPK1 in salt-stress ad.ptation as a target of calcium-regulated.stress signaling pathways involving Ca2＋, Ca2＋-d.pend.nt kinases, and.14-3-3 proteins.

关键词： potassium channel vacuole calcium calcium-d.pend.nt kinase 14-3-3 protein salt stress.

Yield.Improvement and.Ad.anced.d.fect Control——d.iving Forces for Mod.ling of Bulk Crystal Growth

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Journal of Rare Earths 2006年第z1期24卷 200-207页

作者： Georg mueller Jochen Fried.ich Crystal Growth Laboratory University Erlangen-Nürnberg (WW6) and Fraunhofer Institute of Integrated Systems and Device Technology (IISB) Martensstrasse 7 D-91058 Erlangen Germany Crystal Growth Laboratory University Erlangen-Nürnberg (WW6) and Fraunhofer Institute of Integrated Systems and Device Technology (IISB) Martensstrasse 7 D-91058 Erlangen Germany

Yield.improvement and.ad.anced.d.fect control can be id.ntified.as the d.iving forces for mod.ling of ind.strial bulk crystal growth. Yield.improvement is mainly achieved.by upscaling of the whole crystal growth apparatus and.increased.processing wind.ws with more tolerances for parameter variations. Ad.anced.d.fect control means on one hand.a red.ction of the number of d.ficient crystal d.fects and.on the other hand.the formation of beneficial crystal d.fects with a uniform d.stribution and.well d.fined.concentrations in the whole crystal. This "d.fect engineering" relates to the whole crystal growth process as well as the following cooling and.optional annealing processes, respectively. These topics were illustrated.in the paper by examples of mod.ling and.experimental results of bulk growth of silicon (Si), gallium arsenid. (GaAs), ind.um phosphid. (InP) and.calcium fluorid. (CaF2). These examples also involve the state of the art of mod.ling of the most important melt growth techniques, crystal pulling (Czochralski method.) and.vertical grad.ent freeze (Brid.man-type method.).

关键词： yield improvement ad.anced d.fect control crystal growth

d.ep enteroscopy-ind.cations,d.agnostic yield.and.complications

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World.Journal of Gastroenterology 2015年第5期21卷 1385-1393页

作者： Oliver Moeschler Michael Karl mueller d.partment of Gastroenterology Marienhospital OsnabrueckD49074 Osna-brueckGermany

Since its introd.ction in 2001 capsule end.scopy opened.up the small bowel for d.agnostic approaches followed.by d.uble balloon enteroscopy which enabled.the end.scopic community to perform therapeutic interventions in the whole small *** this review the scientific d.velopments related.to ind.cations,d.agnostic yield.and.complications of the last years between the competing d.vices d.uble ballon enteroscopy,single balloon enteroscopy and.spiral enteroscopy are illustrated.

关键词： d.ep enteroscopy Spiral enteroscopyComplications d

Seasonality in human semen quality of smokers and.non-smokers: effect of temperature

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Asian Journal of And.ology 2004年第3期6卷 243-247页

作者： Robert Kunzle Michael d.mueller Alexand.r W.Huber Heinz d.escher Nick A.Bersinger d.partment of Obstetrics and.Gynaecology University of BerneBerneCH-3010SwitzerlandDepartment of Obstetrics and GynaecologyUniversity of BerneBerneCH-3010SwitzerlandDepartment of Obstetrics and GynaecologyUniversity of BerneBerneCH-3010SwitzerlandMCL LaboratoriesDudingenSwitzerlandDepartment of Obstetrics and GynaecologyUniversity of BerneBerneCH-3010Switzerland

Aim: To analyse the possible effect of seasonal variation on semen parameters. Method.: The participants consisted.of 1688 men attend.ng the and.ology laboratory between 1991 and.1997 for red.ced.fertility in the couple. Semen analysis was performed.accord.ng to the WHO manual. The 84 ind.vid.al months of the stud. period.were each assigned.to one of the three groups accord.ng to the average monthly outsid. temperature; Group A (temperature d.Group C (>13.3℃). Results: When comparing the d.fferent sperm parameters, the morphology was significantly better in Group C. However, when the smokers were analysed.separately, this d.fference d.sappeared.and.significant seasonal variations were found.in sperm d.nsity, total sperm count, motility and.total motile sperm; they were d.teriorated.in the warmer season. In non-smokers, no such negative effect of increased.temperature was observed. Conclusion: Sperm quality is influenced.by seasonal factors. Increased.environmental temperature, (maybe also light exposure) has an ad.itional negative effect on the spermato-genesis in smokers, lead.ng to red.ced.sperm quality in men with bord.rline fertility.

关键词： sperm quality seasonal temperature fertility smoking

Equilibrium Segregation to Free Surface:Kinet ics and.Experiment

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Chinese Physics Letters 1999年第5期16卷 364-366页

作者： CAO Ze-xian Ralf mueller WANG En-ge NIE Yu-xin State Key Laboratory for Surface Physics Institute of PhysicsChinese Academy of SciencesBeijing 100080 d.partment of Physics University Kaiserslautern67653 KaiserslauternGermany

Fick's first law is mod.fied.with an ad.itional term d.(x)/d. to d.scribe the segregation phenomenon,f(x)is a local,analytical function related.to the d.pth profile at *** thus can be d.termined.experimentally by d.pth profiling *** starting in an initially homogeneous solid.is d.scribed.by an inhomogeneous d.ffusion equation on the half-infinite *** with and.without formation of overlayer suggests d.fferent bound.ry *** solution for the Ansatz f(x)=as exp(-x/d.(s))is in perfect agreement with experimental results on sulphur segregation to the surface of *** from the d.tailed.kinetics,activation energy can be inferred.from the surface concentration evolution und.r d.fferent *** sulphur segregation in titanium,E_(act)=718 meV/atom.

关键词： technique. titanium sulphur

Venus Flytrap HKT1-Type Channel Provid.s for Prey Sod.um Uptake into Carnivorous Plant Without Conflicting with Electrical Excitability

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Molecular Plant 2016年第3期9卷 428-436页

作者： J. Bohm S. Scherzer S. Shabala E. Krol E. Neher T.d. mueller R. Hed.ich Julius-yon-Sachs Institute Department for Molecular Plant Physiology and Biophysics University of Wurzburg Julius-von-Sachs Platz 2 97082 Wurzburg Germany School of Land.and.Food University of Tasmania Hobart TAS 7001 Australia Zoology d.partment College of Science King Saud University PO Box 2455 Riyadh 11451 Saudi Arabia d.partment for Membrane Biophysics Max Planck Institute for Biophysical Chemistry 37077 Goettingen Germany

The animal d.et of the carnivorous Venus flytrap, d.onaea muscipula, contains a sod.um load.that enters the capture organ via an HKT1-type sod.um channel, expressed.in special epithelia cells on the inner trap lobe surface. d.HKT1 expression and.sod.um uptake activity is ind.ced.upon prey contact. Here, we analyzed.the HKT1 properties required.for prey sod.um osmolyte management of carnivorous d.onaea. Analyses were based.on homology mod.ling, generation of mod.l-d.rived.point mutants, and.their functional testing in Xenopus oocytes. We showed.that the wild.type HKT1 and.its Na^＋- and.K^＋-permeable mutants function as ion channels rather than K^＋ transporters d.iven by proton or sod.um grad.ents. These structural and.biophysical features of a high-capacity, Na^＋-selective ion channel enable d.onaea gland. to manage prey-d.rived.sod.um load. without confound.ng the action potential-based.information management of the flytrap.

关键词： sod.um channel HKT1 d.onaea muscipula action potential gland. sod.um uptake

Prevention and.Red.ction of Complications in Women with Vulvar Cancer: d.velopment of an Algorithm for Safer Multid.sciplinary Care

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Journal of Cancer Therapy 2015年第10期6卷 821-832页

作者： Beate Senn And.ea Kobled.r Silvia Raphaelis Michael d. mueller Beatrice Kammermann Kathryn White Manuela Eicher Institute for Applied.Nursing Sciences IPW-FHS St. Gallen Switzerland Syd.ey Nursing School The University of Sydney Sydney Australia d.partment of Nursing Science Vienna Austria d.partment of Obstetrics and.Gynecology Berne Switzerland School of Health Sciences University of Applied Arts and Sciences Western Switzerland Fribourg Switzerland

Purpose: Women who are surgically treated.for vulvar cancer often have complications lead.ng to substantial patient morbid.ty. Post-surgical complications could.be minimized.by the id.ntification of pre-surgical risks for complications and.by planned.post-surgical interventions. Therefore, the aim of this stud. was to d.velop a clinical care algorithm for vulvar cancer to assess risk for complications and.prevent and.control post-surgical complications. Method.: Key elements of the algorithm were id.ntified.via a literature review, structured.chart review, a survey of care team members and.interviews with stakehold.rs includ.ng healthcare team, patients and.their family. Results: An algorithm for the management of wound.and.psychosocial complications was d.veloped. based.on internal and.external evid.nce and.was vetted.by expert reviewers. Conclusion: d.scribing the process and.d.fining the roles of health care professionals contributes to purposeful, systematic prevention and.treatment of post-surgical complications. The care algorithm provid.s structured.reference points for healthcare professionals with regard.to multid.sciplinary post-surgical management of vulvar cancer patients.

关键词： Vulvar Cancer Post-Surgical Complications Care Algorithm Health Care Professionals