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Estimating the basic reproduction number for single-strain dengue fever epidemics

Infectious Diseases of Poverty 2014年第1期3卷 100-116页

作者： Adnan Khan Muhammad Hassan mudassar imran Department of Mathematics Lahore University of Management SciencesDHALahorePakistan Department of Mathematics Swiss Federal Institute of Technology(ETH)ZurichRämistrasse 1018092 ZurichSwitzerland

Background:Dengue,an infectious tropical disease,has recently emerged as one of the most important mosquito-borne viral diseases in the *** perform a retrospective analysis of the 2011 dengue fever epidemic in Pakistan in order to assess the transmissibility of the *** obtain estimates of the basic reproduction number R0 from epidemic data using different methodologies applied to different epidemic models in order to evaluate the robustness of our ***:We first estimate model parameters by fitting a deterministic ODE vector-host model for the transmission dynamics of single-strain dengue to the epidemic data,using both a basic ordinary least squares(OLS)as well as a generalized least squares(GLS)***,we perform the same analysis for a direct-transmission ODE model,thereby allowing us to compare our results across different *** addition,we formulate a direct-transmission stochastic model for the transmission dynamics of dengue and obtain parameter estimates for the stochastic model using Markov chain Monte Carlo(MCMC)*** each of the cases we have considered,the estimate for the basic reproduction number R0 is initially greater than unity leading to an epidemic ***,control measures implemented several weeks after the initial outbreak successfully reduce R0 to less than unity,thus resulting in disease ***,it is observed that there is strong agreement in our estimates for the pre-control value of R0,both across different methodologies as well across different ***,there are also significant differences between our estimates for the post-control value of the basic reproduction number across the two different ***:In conclusion,we have obtained robust estimates for the value of the basic reproduction number R0 associated with the 2011 dengue fever epidemic before the implementation of public health control ***,we have shown that there is close agreement

关键词： Epidemiology Dengue fever Statistical inference Stochastic model Markov chain Monte Carlo

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Optimal control analysis of Ebola disease with control strategies of quarantine and vaccination

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Infectious Diseases of Poverty 2016年第1期5卷 648-659页

作者： Muhammad Dure Ahmad Muhammad Usman Adnan Khan mudassar imran Department of Mathematics Prince Sultan UniversityRiyadhKingdom of Saudi Arabia Department of Mathematics University of DaytonDaytonOHUSA Department of Mathematics Lahore University of Management SciencesLahorePakistan Department of Mathematics and Natural Sciences GULF University for Science and TechnologyMishrefKuwait

Background:The 2014 Ebola epidemic is the largest in history,affecting multiple countries in West *** isolated cases were also observed in other regions of the ***:In this paper,we introduce a deterministic SEIR type model with additional hospitalization,quarantine and vaccination components in order to understand the disease *** control strategies,both in the case of hospitalization(with and without quarantine)and vaccination are used to predict the possible future outcome in terms of resource utilization for disease control and the effectiveness of vaccination on sick ***,with the help of uncertainty and sensitivity analysis we also have identified the most sensitive parameters which effectively contribute to change the disease *** have performed mathematical analysis with numerical simulations and optimal control strategies on Ebola virus ***:We used dynamical system tools with numerical simulations and optimal control strategies on our Ebola virus *** original model,which allowed transmission of Ebola virus via human contact,was extended to include imperfect vaccination and *** the qualitative analysis of all three forms of Ebola model,numerical techniques,using MATLAB as a platform,were formulated and analyzed in *** simulation results support the claims made in the qualitative ***:Our model incorporates an important component of individuals with high risk level with exposure to disease,such as front line health care workers,family members of EVD patients and Individuals involved in burial of deceased EVD patients,rather than the general population in the affected *** analysis suggests that in order for R0(i.e.,the basic reproduction number)to be less than one,which is the basic requirement for the disease elimination,the transmission rate of isolated individuals should be less than one-fourth of that for non-isolated *** analysis also predicts,

关键词： Epidemiology Ebola virus disease Optimal control strategies Disease transmission

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Estimating the basic reproductive ratio for the Ebola outbreak in Liberia and Sierra Leone

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Infectious Diseases of Poverty 2015年第1期4卷 114-121页

作者： Adnan Khan Mahim Naveed Muhammad Dur-e-Ahmad mudassar imran Department of Mathematics Lahore University of Management SciencesLahorePakistan Department of Mathematics State University of New York at PlattsburghPlattsburghNYUSA Department of Mathematics Waterloo UniversityWaterlooONCanada Department of Mathematics and Natural Sciences GULF University for Science and TechnologyMubarak Al-AbdullahWest MishrefKuwait

Background:Ebola virus disease has reemerged as a major public health crisis in Africa,with isolated cases also observed globally,during the current ***:To estimate the basic reproductive ratio R0,which is a measure of the severity of the outbreak,we developed a SEIR(susceptible-exposed-infected-recovered)type deterministic model,and used data from the Centers for Disease Control and Prevention(CDC),for the Ebola outbreak in Liberia and Sierra *** different data sets are available:one with raw reported data and one with corrected data(as the CDC suspects under-reporting).Results:Using a deterministic ordinary differential equation transmission model for Ebola epidemic,the basic reproductive ratio R0 for Liberia resulted to be 1.757 and 1.9 for corrected and uncorrected case data,*** Sierra Leone,R0 resulted to be 1.492 and 1.362 for corrected and uncorrected case data,*** each of the two cases we considered,the estimate for the basic reproductive ratio was initially greater than unity leading to an epidemic ***:We obtained robust estimates for the value of R0 associated with the 2014 Ebola outbreak,and showed that there is close agreement between our estimates of *** of our model also showed that effective isolation is required,with the contact rate in isolation less than one quarter of that for the infected non-isolated population,and that the fraction of high-risk individuals must be brought to less than 10%of the overall susceptible population,in order to bring the value of R0 to less than 1,and hence control the outbreak.

关键词： Epidemiology Ebola virus disease Transmission model Basic reproductive ratio

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Revisiting the N = 1 supersymmetric trinification models from intersecting D6-branes

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Communications in Theoretical Physics 2024年第9期76卷 29-38页

作者： Adeel Mansha Tianjun Li mudassar Sabir Department of Physics Zhejiang Normal University Zhejiang Institute of Photoelectronics Zhejiang Normal University Centre For High Energy Physics University of the Punjab CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences School of Physical Sciences University of Chinese Academy of Sciences School of Physics University of Electronic Science and Technology of China

We revisit the construction of the N= 1 supersymmetric trinification models with gauge group U（3）C× U（3）L× U（3）Rin Type ⅡA string theory on T6（Z2×Z2）orientifold with intersecting D6-branes. The non-trivial K-theory conditions and tadpole cancellation conditions severely restrict the number of allowed models even for the case of rectangular two-tori. Using a supervised search algorithm, we find a few four-family models where the highest wrapping number is 2. For these models, we present the complete particle spectra and the gauge coupling relations at the string-scale.

关键词： D branes string phenomenology trinification

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Recent Developments in Authentication Schemes Used in Machine-Type Communication Devices in Machine-to-Machine Communication: Issues and Challenges

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Computers, Materials & Continua 2024年第4期79卷 93-115页

作者： Shafi Ullah Sibghat Ullah Bazai Mohammad imran Qazi mudassar Ilyas Abid Mehmood Muhammad Asim Saleem Muhmmad Aasim Rafique Arsalan Haider Ilyas Khan Sajid Iqbal Yonis Gulzar Kauser Hameed Department of Computer Engineering Balochistan University of Information TechnologyEngineering and Management SciencesQuetta87300Pakistan Department of Information Technology Balochistan University of Information TechnologyEngineeringand Management SciencesQuetta87300Pakistan Department of Information Systems College of Computer Sciences and Information TechnologyKing Faisal UniversityHofuf in Al-Ahsa31982Saudi Arabia Department of Management Information Systems College of Business AdministrationKing Faisal UniversityHofuf in Al-Ahsa31982Saudi Arabia Department of Software Engineering College of ComputingRiphah International UniversityFaisalabad44000Pakistan Department of Electrical Engineering Balochistan University of Information Technology Engineeringand Management SciencesQuetta87300Pakistan Department of Mathematics College of Science Al-ZulfiMajmaah UniversityAl-Majmaah11952Saudi Arabia

Machine-to-machine (M2M) communication plays a fundamental role in autonomous IoT (Internet of Things)-based infrastructure, a vital part of the fourth industrial revolution. Machine-type communication devices(MTCDs) regularly share extensive data without human intervention while making all types of decisions. Thesedecisions may involve controlling sensitive ventilation systems maintaining uniform temperature, live heartbeatmonitoring, and several different alert systems. Many of these devices simultaneously share data to form anautomated system. The data shared between machine-type communication devices (MTCDs) is prone to risk dueto limited computational power, internal memory, and energy capacity. Therefore, securing the data and devicesbecomes challenging due to factors such as dynamic operational environments, remoteness, harsh conditions,and areas where human physical access is difficult. One of the crucial parts of securing MTCDs and data isauthentication, where each devicemust be verified before data transmission. SeveralM2Mauthentication schemeshave been proposed in the literature, however, the literature lacks a comprehensive overview of current M2Mauthentication techniques and the challenges associated with them. To utilize a suitable authentication schemefor specific scenarios, it is important to understand the challenges associated with it. Therefore, this article fillsthis gap by reviewing the state-of-the-art research on authentication schemes in MTCDs specifically concerningapplication categories, security provisions, and performance efficiency.

关键词： Authentication cyber security internet of things machine-type communication devices machine-to-machine communication

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The Effects of a Backward Bifurcation on a Continuous Time Markov Chain Model for the Transmission Dynamics of Single Strain Dengue Virus

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Applied Mathematics 2013年第4期4卷 663-674页

作者： Adnan Khan Muhammad Hassan mudassar imran Centre for Advanced Studies in Mathematics Lahore University of Management Sciences Lahore Pakistan

Global incidence of dengue, a vector-borne tropical disease, has seen a dramatic increase with several major outbreaks in the past few decades. We formulate and analyze a stochastic epidemic model for the transmission dynamics of a single strain of dengue virus. The stochastic model is constructed using a continuous time Markov chain (CTMC) and is based on an existing deterministic model that suggests the existence of a backward bifurcation for some values of the model parameters. The dynamics of the stochastic model are explored through numerical simulations in this region of bistability. The mean of each random variable is numerically estimated and these are compared to the dynamics of the deterministic model. It is observed that the stochastic model also predicts the co-existence of a locally asymptotically stable disease-free equilibrium along with a locally stable endemic equilibrium. This co-existence of equilibria is important from a public health perspective because it implies that dengue can persist in populations even if the value of the basic reproduction number is less than unity.

关键词： Epidemiology Dengue Fever Backward Bifurcation Stochastic Model

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Deep Convolutional Neural Networks for Accurate Classification of Gastrointestinal Tract Syndromes

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Computers, Materials & Continua 2024年第1期78卷 1207-1225页

作者： Zahid Farooq Khan Muhammad Ramzan mudassar Raza Muhammad Attique Khan Khalid Iqbal Taerang Kim Jae-Hyuk Cha Department of Computer Science COMSATS University IslamabadWah CampusWah47040Pakistan Department of Computer Science and Mathematics Lebanese American UniversityBeirut13-5053Lebanon Department of Computer Science HITEC UniversityTaxila47080Pakistan Department of Computer Science COMSATS University IslamabadAttock CampusAttock43600Pakistan Department of Computer Science Hanyang UniversitySeoul04763Korea

Accurate detection and classification of artifacts within the gastrointestinal(GI)tract frames remain a significant challenge in medical image *** science combined with artificial intelligence is advancing to automate the diagnosis and treatment of numerous *** to this is the development of robust algorithms for image classification and detection,crucial in designing sophisticated systems for diagnosis and *** study makes a small contribution to endoscopic image *** proposed approach involves multiple operations,including extracting deep features from endoscopy images using pre-trained neural networks such as Darknet-53 and ***,feature optimization utilizes the binary dragonfly algorithm(BDA),with the fusion of the obtained feature *** fused feature set is input into the ensemble subspace k nearest neighbors(ESKNN)*** Kvasir-V2 benchmark dataset,and the COMSATS University Islamabad(CUI)Wah private dataset,featuring three classes of endoscopic stomach images were *** assessments considered various feature selection techniques,including genetic algorithm(GA),particle swarm optimization(PSO),salp swarm algorithm(SSA),sine cosine algorithm(SCA),and grey wolf optimizer(GWO).The proposed model excels,achieving an overall classification accuracy of 98.25% on the Kvasir-V2 benchmark and 99.90% on the CUI Wah private *** approach holds promise for developing an automated computer-aided system for classifying GI tract syndromes through endoscopy images.

关键词： Feature fusion Darknet-53 Xception binary dragonfly algorithm ensemble

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Bond-Slip Behavior of Steel Bar and Recycled Steel Fibre-Reinforced Concrete

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Journal of Renewable Materials 2024年第1期12卷 167-186页

作者： Ismail Shah Jing Li Nauman Khan Hamad R.Almujibah Muhammad mudassar Rehman Ali Raza Yun Peng School of Architecture and Civil Engineering Yunnan Agricultural UniversityKunming650000China Institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu610041China Yunnan International Joint R&D Center of Smart Agriculture and Water Security Yunnan Agricultural UniversityKunming650201China School of Water Conservancy Yunnan Agricultural UniversityKunming650201China School of Civil Engineering Guizhou UniversityGuiyang550025China Department of Civil Engineering College of EngineeringTaif UniversityP.O.Box 11099Taif City21974Saudi Arabia School of Civil Engineering Zhengzhou UniversityZhengzhou450001China

Recycled steel fiber reinforced concrete is an innovative construction material that offers exceptional mechanical properties and *** is considered a sustainable material due to its low carbon footprint and environmental friendly *** study examines the key influencing factors that affect the behavior of this material,such as the steel fiber volume ratio,recycled aggregate replacement rate,concrete strength grade,anchorage length,and stirrup *** study investigates the bond failure morphology,bond-slip,and bond strength constitutive relationship of steel fiber recycled *** results show that the addition of steel fibers at 0.5%,1.0%,and 1.5%volume ratios can improve the ultimate bond strength of pull-out specimens by 9.05%,6.94%,and 5.52%,*** replacement rate of recycled aggregate has minimal effect on the typical bond strength of pull-out ***,the ultimate bond strengths of pull-out specimens with concrete strength grades C45 and C60 have improved compared to those with C30 *** specimens with longer anchorage lengths exhibit lower ultimate bond strength,with a reduction of 33.19%and 46.37%for anchorage lengths of 5D and 7D,respectively,compared to those without *** restraint of 1φ8 and 2φ8 improves the ultimate bond strength by 5.29%and 6.90%,*** fibers have a significant effect on the behavior of concrete after it cracks,especially during the stable expansion stage,crack instability expansion stage,and failure stage.

关键词： Recycled coarse aggregates(RCA) steel fiber bonding performance bond-slip environmental challenges

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Modeling transmission dynamics of Ebola virus disease

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International Journal of Biomathematics 2017年第4期10卷 297-331页

作者： mudassar imran Adnan Khan Ali R. Ansari Syed Touqeer Hussain Shah International Center for Applied Mathematics and Computational Bioengineering Department of Mathematics and Natural Sciences Gulf University for Science and Technology Hawally Kuwait Department of Mathematics Lahore University of Management Sciences Lahore Pakistan

Ebola virus disease (EVD) has emerged as a rapidly spreading potentially fatal disease. Several studies have been performed recently to investigate the dynamics of EVD. In this paper, we study the transmission dynamics of EVD by formulating an SEIR-type transmission model that includes isolated individuals as well as dead individuals that are not yet buried. Dynamical systems analysis of the model is performed, and it is consequently shown that the disease-free steady state is globally asymptotically stable when the basic reproduction number, ℛ 0 is less than unity. It is also shown that there exists a unique endemic equilibrium when ℛ 0 > 1 . Using optimal control theory, we propose control strategies, which will help to eliminate the Ebola disease. We use data fitting on models, with and without isolation, to estimate the basic reproductive numbers for the 2014 outbreak of EVD in Liberia and Sierra Leone.

关键词： Ebola virus disease endemic equilibrium basic reproduction number hospitalization infectiousness optimal control transmission dynamics time series data fitting

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不同国家黄油和黄油乳脂理化性质的比较评价

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中国油脂 2024年第7期49卷 29-39页

作者：邹孝强蒋邦智郑磊胡纪洁潘月超王钦民 IMAD Khan mudassar Hussain 江南大学食品学院食品科学与资源挖掘国家重点实验室国家功能食品工程技术研究中心粮食发酵与食品生物制造国家工程研究中心江苏无锡214122 伽力森食品生物科技(江苏)有限公司江苏泰州225700

为帮助食品生产商和消费者选择适用于不同应用途径的黄油,并为生产更受消费者喜爱的黄油替代品提供理论支持,选取了11个国家的黄油并提取黄油乳脂,对黄油及黄油乳脂的理化性质进行了系统的比较评价。结果表明:11个国家黄油中的脂肪、水... 详细信息

为帮助食品生产商和消费者选择适用于不同应用途径的黄油,并为生产更受消费者喜爱的黄油替代品提供理论支持,选取了11个国家的黄油并提取黄油乳脂,对黄油及黄油乳脂的理化性质进行了系统的比较评价。结果表明:11个国家黄油中的脂肪、水分、蛋白质含量和滑动熔点分别为82.97%~86.40%、12.84%~16.14%、0.45%~0.78%、31.5~33.9℃,酸值(KOH)和过氧化值分别不超过0.32 mg/g、0.029 g/100 g。中国黄油的L值最高(86.87),而新西兰黄油的b值最高(35.28)。所有黄油共检出29种脂肪酸和42种甘油三酯,蛋白质主要由αs1-酪蛋白、β-酪蛋白、κ-酪蛋白、α-乳白蛋白和Adipophilin组成。爱尔兰黄油的不饱和脂肪酸含量最高(35.65%),固体脂肪含量(SFC)较低,而美国、荷兰和澳大利亚黄油的饱和脂肪酸和SFC含量较高。不同国家的黄油和黄油乳脂的晶体均为均匀精细的球晶,其中美国黄油和黄油乳脂的晶体均呈现部分聚集,且绝大多数晶体主要由β′型晶体组成。质地和流变学分析表明,爱尔兰黄油和黄油乳脂的硬度最低,所有黄油和黄油乳脂都表现出良好的黏弹性和剪切变稀性能。综上,不同国家黄油在基本理化性质、脂肪酸和甘油酯组成、SFC及硬度等方面存在差异,在食品工业中需要根据成品、加工工艺等有针对性地选择黄油,在新型人造奶油的构建中,也可依据各黄油特点进行定向研究。

关键词：黄油黄油乳脂理化性质晶体质构流变

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