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Nuclear Science and Techniques 2024年第1期35卷 18-33页

作者： Xi-Guang Cao Yan-Long Chang Kai Chen Emilio Ciuffoli Li-Min Duan Dong-Liang Fang Chao-Song Gao Surja K.Ghorui Peng-Chong Hu Qiang Hu Si-Yuan Huang Ze-Yu Huang Lei Lang Yu-Lan Li Zhi-Jie Li Tian-Yu Liang Jun Liu Chen-Gui Lu Fa-Tai Mai Yuan Mei Hao Qiu Xiang-Ming Sun xiao-Xing Tang Hu-Lin Wang Qian-Ming Wang Le xiao mu-yun xiao Jian-Yu Xin Nu Xu Peng Yang Yi-Chen Yang Zhen Yang Zong-Yang Yu Dong-Liang Zhang Jun-Wei Zhang Cheng-Xin Zhao Dou Zhu NνDEx-100 collaboration Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210China Lanzhou University Lanzhou 730000China Central China Normal University Wuhan 430079China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Lawrence Berkeley National Laboratory BerkeleyCA 94720USA North China University of Water Resources and Electric Power Zhengzhou 450045China 不详

Observing nuclear neutrinoless double beta (0vββ) decay would be a revolutionary result in particle physics.Observing such a decay would prove that the neutrinos are their own antiparticles,help to study the absolute mass of neutrinos,explore the origin of their mass,and may explain the matter-antimatter asymmetry in our universe by lepton number violation.We propose developing a time projection chamber (TPC) using high-pressure ^(82)SeF_(6) gas and Topmetal silicon sensors for readout in the China Jinping Underground Laboratory (CJPL) to search for neutrinoless double beta decay of82Se,called the NvDEx experiment.Besides being located at CJPL with the world’s thickest rock shielding,NvDEx combines the advantages of the high Qββ(2.996 MeV) of82Se and the TPC’s ability to distinguish signal and background events using their different topological characteristics.This makes NvDEx unique,with great potential for low-background and high-sensitivity 0 vββsearches.NvDEx-100,a NvDEx experiment phase with 100 kg of SeF_(6)gas,is being built,with plans to complete installation at CJPL by 2025.This report introduces 0 vββ physics,the NvDEx concept and its advantages,and the schematic design of NvDEx-100,its subsystems,and background and sensitivity estimation.

关键词： Neutrinoless double beta decay Time projection chamber ^(82)SeF_(6) China Jinping Underground Laboratory

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Diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging parameters and serum tumor markers in rectal carcinoma prognosis

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 1796-1807页

作者： Ren-Qi mu Jun-Wei Lv Cai-yun Ma xiao-Hui Ma Dong Xing Hou-Sheng Ma Department of Radiology Yantai Mountain HospitalYantai 264001Shandong ProvinceChina Department of Radiology Yantai Yuhuangding HospitalYantai 264000Shandong ProvinceChina Department of Gynaecology Yantai Yuhuangding HospitalYantai 264000Shandong ProvinceChina The First Clinical Medical College Xinjiang Medical UniversityUrumqi 830011Xinjiang Uygur Autonomous RegionChina

BACKGROUND Rectal carcinoma(RC),one of the most common malignancies globally,presents an increasing incidence and mortality year by year,especially among young people,which seriously affects the prognosis and quality of life of patients.At present,dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)parameters and serum carbohydrate antigen 19-9(CA19-9)and CA125 Levels have been used in clinical practice to evaluate the T stage and differentiation of RC.However,the accuracy of these evaluation modalities still needs further research.This study explores the application and value of these methods in evaluating the T stage and differentiation degree of RC.AIM To analyze the diagnostic performance of DCE-MRI parameters combined with serum tumor markers(TMs)in assessing pathological processes and prognosis of RC patients.METHODS A retrospective analysis was performed on 104 RC patients treated at Yantai Yuhuangding Hospital from May 2018 to January 2022.Patients were categorized into stages T1,T2,T3,and T4,depending on their T stage and differentiation degree.In addition,they were assigned to low(L group)and moderate-high differentiation(M+H group)groups based on their differentiation degree.The levels of DCE-MRI parameters and serum CA19-9 and CA125 in different groups of patients were compared.In addition,the value of DCE-MRI parameters[volume transfer constant(Ktrans),rate constant(Kep),and extravascular extracellular volume fraction(Ve)in assessing the differentiation and T staging of RC patients was discussed.Furthermore,the usefulness of DCE-MRI parameters combined with serum CA19-9 and CA125 Levels in the evaluation of RC differentiation and T staging was analyzed.RESULTS Ktrans,Ve,CA19-9 and CA125 were higher in the high-stage group and L group than in the low-stage group and M+H Group,respectively(P<0.05).The areas under the curve(AUCs)of the Ktran and Ve parameters were 0.638 and 0.694 in the diagnosis of high and low stages,respectively,and 0.672 and 0.725 in diagnosing moderate-high and low differe

关键词： Rectal carcinoma Volume transfer constant Rate constant Extravascular extracellular volume fraction Serum carbohydrate antigen 19-9 Serum carbohydrate antigen 125

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Role of aminopeptidase N-like in the acquisition of begomoviruses by Bemisia tabaci,the whitefly vector

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Insect Science 2024年第3期31卷 707-719页

作者： yun-yun Fan Yao Chi Na Chen Wilmer J.Cuellar xiao-Wei Wang Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang ProvinceInstitute of Insect SciencesZhejiang UniversityHangzhouChina Zhejiang Tianmushan National Nature Reserve Administration HangzhouChina Institute of Plant Protection Liaoning Academy of Agricultural SciencesShenyangChina Virology Laboratory Cassava ProgramInternational Center for Tropical Agriculture(CIAT)PalmiraColombia

Sri Lankan cassava mosaic virus(SLCMV)is a prominent causative agent of cassava mosaic disease in Asia and relies on the whitefly Bemisia tabaci cryptic complex for its transmission.However,the molecular mechanisms involved in SLCMV transmission by B.tabaci have yet to be understood.In this study,we identified an aminopeptidase N-like protein(BtAPN)in B.tabaci Asia II 1,an efficient vector of SLCMV,which is involved in the SLCMV transmission process.Through the use of glutathione S-transferase pull-down assay and LC-MS/MS analysis,we demonstrated the interaction between BtAPN and the coat protein(CP)of SLCMV.This interaction was further confirmed in vitro,and we observed an induction of BtAPN gene expression following SLCMV infection.By interfering with the function of BtAPN,the quantities of SLCMV were significantly reduced in various parts of B.tabaci Asia II 1,including the whole body,midgut,hemolymph,and primary salivary gland.Furthermore,we discovered that BtAPN is conserved in B.tabaci Middle East-Asia Minor 1(MEAM1)and interacts with the CP of tomato yellow leaf curl virus(TYLCV),a begomovirus known to cause severe damage to tomato production.Blocking BtAPN with antibody led to a significant reduction in the quantities of TYLCV in whitefly whole body and organs/tissues.These results demonstrate that BtAPN plays a generic role in interacting with the CP of begomoviruses and positively regulates their acquisition by the whitefly.

关键词： BtAPN coat protein SLCMV TYLCV virus acquisition whitefly

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Density peak clustering using tensor network

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Science China(Information Sciences) 2024年第3期67卷 321-322页

作者： xiao SHI yun SHANG Institute of Mathematics Academy of Mathematics and Systems ScienceChinese Academy of Sciences School of Mathematical Sciences University of Chinese Academy of Sciences National Center for Mathematics and Interdisciplinary Sciences Key Laboratory of ManagementDecision and Information SystemsAcademy of Mathematics and Systems ScienceChinese Academy of Sciences

Tensor networks have been a powerful tool in simulating many-body physics and have recently gained recognition in the machine learning community due to their remarkable representation capabilities. However, using tens... 详细信息

关键词： Tensors

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Cell metabolism pathways involved in the pathophysiological changes of diabetic peripheral neuropathy

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Neural Regeneration Research 2024年第3期19卷 598-605页

作者： Yaowei Lv Xiangyun Yao xiao Li Yuanming Ouyang Cunyi Fan yun Qian Department of Orthopedics Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina Shanghai Engineering Research Center for Orthopaedic Material Innovation and Tissue Regeneration ShanghaiChina Youth Science and Technology Innovation Studio of Shanghai Jiao Tong University School of Medicine ShanghaiChina College of Fisheries and Life Science Shanghai Ocean UniversityShanghaiChina

Diabetic peripheral neuropathy is a common complication of diabetes mellitus.Elucidating the pathophysiological metabolic mechanism impels the generation of ideal therapies.However,existing limited treatments for diabetic peripheral neuropathy expose the urgent need for cell metabolism research.Given the lack of comprehensive understanding of energy metabolism changes and related signaling pathways in diabetic peripheral neuropathy,it is essential to explore energy changes and metabolic changes in diabetic peripheral neuropathy to develop suitable treatment methods.This review summarizes the pathophysiological mechanism of diabetic peripheral neuropathy from the perspective of cellular metabolism and the specific interventions for different metabolic pathways to develop effective treatment methods.Various metabolic mechanisms(e.g.,polyol,hexosamine,protein kinase C pathway)are associated with diabetic peripheral neuropathy,and researchers are looking for more effective treatments through these pathways.

关键词： cell metabolism diabetic peripheral neuropathy peripheral nerve injury protein kinase C pathway reactive oxygen species.

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A Possible X-ray Quasi-periodic Oscillation in the Narrow-line Seyfert 1 Galaxy Mrk 142

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Research in Astronomy and Astrophysics 2024年第6期24卷 193-202页

作者： xiao-Gu Zhong Jian-Cheng Wang Yong-yun Chen xiao-Ling Yu College of Physics and Electronic Engineering Qujing Normal University yunnan Observatories Chinese Academy of Sciences

A possible quasi-periodic oscillation（QPO） at frequency 7.045 × 10-5Hz is found in the narrow-line Seyfert 1galaxy Mrk 142 in the data of XMM-Newton collected on 2020 April 11. We find that the QPO signal is statistically significantly larger than the 5σ level and highly coherent with quality factor Q > 5 at the 0.3–10 keV band by using the method of the Lomb–Scargle Periodogram, the Weighted Wavelet Z-transform and the REDFIT.We analyze the data in 0.3–0.6 keV, 0.6–1 keV, 1–3 keV and 3–10 keV energy bands, and find obvious QPO signals at 0.3–0.6 keV and 1–3 keV bands. We then analyze the time-average spectra and time variability at the QPO frequency of 7.045 × 10-5Hz, and use a model to fit them. We find that the QPO signal mainly comes from the X-ray hot corona.

关键词： accretion accretion disks galaxies: Seyfert radiation mechanisms: general X-rays: galaxies

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Therapeutic effect of manual massage on early postpartum rectus abdominis separation and postpartum depression

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World Journal of Psychiatry 2024年第5期14卷 678-685页

作者： yun Chen xiao-Yan Sun Cheng Qian xiao-Xing Zhang Yin-Jian Zhou Hong-yun Zhang Zhen-Wei Xie Department of Gynecology Women’s Hospital School of Medicine Zhejiang UniversityHangzhou 310006Zhejiang ProvinceChina Department of Obstetrics and Gynecology Huzhou Maternity and Child Health Care HospitalHuzhou 313000Zhejiang ProvinceChina Department of Surgery Huzhou Maternity and Child Health Care HospitalHuzhou 313000Zhejiang ProvinceChina Department of Obstetrics Huzhou Maternity and Child Health Care HospitalHuzhou 313000Zhejiang ProvinceChina Department of Ultrasound Women’s Hospital School of Medicine Zhejiang UniversityHangzhou 310006Zhejiang ProvinceChina

BACKGROUND Rectus abdominis separation(DRA)affects pelvic stability and body image.No studies have explored the effects of manual massage on early postpartum DRA and postpartum depression.AIM To analyze the curative effect of massage on early postpartum DRA and its impact on postpartum depression and thus its ability promote the overall psychosomatic rehabilitation of postpartum women.METHODS Data were retrospectively collected on 70 primiparous women with postpartum DRA who underwent rehabilitation at the Postpartum Rehabilitation Center of Huzhou Maternal and Child Health Hospital from October 2022 to September 2023.The patients were divided into the Group S(35 cases,biomimetic electrical stimulation treatment)and Group L(35 cases,biomimetic electrical stimulation combined with manual massage treatment).Baseline data,the edinburgh postpartum depression scale(EPDS)score,and the visual analog scale(VAS)scores for rectus abdominis distance,waist circumference,and lower back pain before and after treatment were compared.RESULTS No significant differences were found in the baseline data,rectus abdominis distance,waist circumference,and VAS and EPDS scores between the two groups before treatment(P>0.05).After treatment,the distance between rectus abdominis and waist circumference in Group L were significantly smaller than those in Group S(P<0.05).Furthermore,lower back pain(VAS score)and the EPDS score in Group L were significantly lower than those in Group S(P<0.05).CONCLUSION Manual massage can significantly reduce early postpartum DRA,waist circumference,and back pain and improve the patient’s mental state and postpartum depression.

关键词： Manual massage Postpartum Rectus abdominis muscle separation Postpartum depression

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Finite barrier bound state

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Light(Science & Applications) 2024年第4期13卷 664-671页

作者： Tao Liu Kai Bai Yicheng Zhang Duanduan Wan yun Lai C.T.Chan Meng xiao Key Laboratory of Artificial Micro-and Nano-structures of Ministry of Education and School of Physics and Technology Wuhan University430072 WuhanChina. National Laboratory of Solid State Microstructures School of Physicsand Collaborative Innovation Center of Advanced MicrostructuresNanjing University210093 NanjingChina. Department of Physics The Hong Kong University of Science and TechnologyClear Water BayKowloon999077Hong KongChina. Wuhan Institute of Quantum Technology 430206 WuhanChina

A boundary mode localized on one side of a finite-size lattice can tunnel to the opposite side which results in unwanted couplings.Conventional wisdom tells that the tunneling probability decays exponentially with the size of the system which thus requires many lattice sites before eventually becoming negligibly small.Here we show that the tunneling probability for some boundary modes can apparently vanish at specific wavevectors.Thus,similar to bound states in the continuum,a boundary mode can be completely trapped within very few lattice sites where the bulk bandgap is not even well-defined.More intriguingly,the number of trapped states equals the number of lattice sites along the normal direction of the boundary.We provide two configurations and validate the existence of this peculiar finite barrier-bound state experimentally in a dielectric photonic crystal at microwave frequencies.Our work offers extreme flexibility in tuning the coupling between localized states and channels as well as a new mechanism that facilitates unprecedented manipulation of light.

关键词： boundary state eventually

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Effect of Maternal DEHP Exposure on Lipid Metabolism in Adult Male Rats and the Antagonistic Effect of Genistein

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Biomedical and Environmental Sciences 2024年第3期37卷 315-319页

作者： ZHANG yun Bo LI Jiang Li TIAN Jie NA xiao Lin Department of Environmental Hygiene Public Health CollegeHarbin Medical UniversityHarbin 150081HeilongjiangChina

Lipid metabolism refers to the biochemical processes involved in synthesising,storing,utilising,and breaking down lipids in living organisms.Lipids are essential for various physiological functions,including energy storage,insulation,protection of organs,and the formation of cell membranes.Aberrations in lipid metabolism can lead to a number of health issues,such as atherosclerosis,obesity,and type 2 diabetes,etc.[1].Environmental factors,genetics,and lifestyle factors are some of the factors that can contribute to the development of dyslipidemia.Currently,there is a growing academic interest in the impact of environmental factors.

关键词： Lipid metabolism organs

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Intrinsically asymmetric atomic character regulates piezoelectricity in two-dimensional materials

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Frontiers of physics 2024年第3期19卷 153-162页

作者： yun-Qin Li Qi-Wen He Dai-Song Tang xiao Shang xiao-Chun Wang School of Physics Science and Information Technology Liaocheng UniversityLiaocheng 252000China Key Laboratory of Polar Materials and Devices Ministry of EducationDepartment of ElectronicsEast China Normal UniversityShanghai 200241China Institute of Atomic and Molecular Physics Jilin UniversityChangchun 130012China

Decreasing of layer thickness causes the decrease of polarization until it disappears due to the existence of depolarization field.Therefore,the search for strong piezoelectric materials is highly desirable for multifunctional ultra-thin piezoelectric devices.Herein,we propose a common strategy for achieving strong piezoelectric materials through the electronic asymmetry induced by the intrinsically asymmetric atomic character of different chalcogen atoms.Accordingly,in the tetrahedral lattice structures,for example,M4X3Y3(M=Pd/Ni,X/Y=S,Se or Te,X≠Y)monolayers are proved to display excellent out-of-plane piezoelectricity.Ni4Se3Te3 possesses the largest piezoelectric coefficient d33 of 61.57 pm/V,which is much larger than that of most 2D materials.Enhancing the electronic asymmetry further increases the out-of-plane piezoelectricity of Janus M4X3Y3 materials.Correspondingly,the out-of-plane piezoelectricity is positively correlated with the ratio of electronegativity difference(Red)and the electric dipole moment(P).This work provides alternative materials for energy harvesting nano-devices or self-energized wearable devices,and supplies a valuable guideline for predicting 2D materials with strong out-of-plane piezoelectricity.

关键词： piezoelectricity intrinsically asymmetric atomic character ratio of electronegativity difference electric dipole moment first-principles calculations

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