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China Foundry 2024年第2期21卷 168-174页

作者： Zhi-yong Zhang jiao-jiao Cheng Jia-qi Xie Shi-bing Liu Kun Shi Jun Zhao Shenyang Research Institute of Foundry Co. Ltd.CAMShenyang 110022China National Key Laboratory of Advanced Casting Technologies Shenyang 110022China

Titanium matrix composites reinforced with ceramic particles are considered a promising engineering material due to their combination of high specific strength,low density,and high *** this study,the TA15-based composites reinforced with a volume fraction of 10% to 25%(TiB+TiC)were prepared using powder metallurgy and casting *** characterization and phase constitution were examined using optical microscopy(OM),scanning electron microscopy(SEM),and X-ray diffraction(XRD).In addition,the microhardness,room temperature(RT)and high temperature(HT)tensile properties of the composites were *** revealed that the reinforcements are distributed uniformly even in the composites with a high volume of TiB and ***,as the volume fraction exceeds 15%,TiB and TiC particles become coarsening and exhibit rod-like and dendritic-like *** increases gradually from 321.2 HV for the base alloy to a maximum of 473.3 HV as the reinforcement increases to 25vol.%.Tensile test results indicate that a reinforcement volume fraction above 20% is beneficial for enhancing tensile strength and yield strength at high temperatures,but it has an adverse effect on room temperature ***,if the reinforcement volume fraction is below 20%,it can improve high-temperature elongation when the temperature exceeds 600℃.

关键词： titanium matrix composites microstucture microhardness tensile properties in-situ synthesis

A recyclable method for titanium extraction and oxygen evolution from Ti-bearing slags

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Fundamental Research 2024年第1期4卷 86-94页

作者： Zhenghao Pu Wei Wang Zhe Wang Mingyin Kou Yiwa Luo Jianbang Ge xin Tao Mingyong Wang Shuqiang jiao State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519080China

Despite its existence for more than 80 years,the titanium industry is still challenged by massive carbon emissions,high production costs,and large resource *** than one hundred million tons of Ti-bearing blast furnace slag(TB-slag)has been discarded in China because of the difficulty of reutilization,which requires efficient titanium extraction and recovery *** paper describes a low-cost,carbon-emission-free method for Ti extraction and oxygen evolution via molten oxide electrolysis(MOE)vacuum *** a comprehensive analysis of the binding energies and activities of liquid metals,the highlights of our study are as follows.1)Sb has the best preferential deposition of Ti among a series of high-Ti-affinitive liquid metal cathodes(Cu,Ni,Pb,Sn,and Sb).2)The Ir anode was first used in TB-slag with IrO_(2) formed on its surface to protect it from further corrosion.3)An alloy containing Ti and Ca can be obtained by MOE,and Ti and Ca metals can be refined by further vacuum distillation.4)A closed loop is formed in the overall process owing to the recyclable Sb cathode and continuous feeding of TB-slag into the *** simple,low-cost,and environmentally friendly method can realize the efficient utilization of Ti resources and achieve carbon neutrality.

关键词： Titanium Molten oxide electrolysis Inert anodeLiquid cathode Depolarization

A Possible γ-Ray Pulsation from PSR J1740-5340B in the Globular Cluster NGC 6397

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Research in Astronomy and Astrophysics 2024年第1期24卷 285-291页

作者： jiao Zheng Pengfei Zhang Li Zhang Department of Astronomy School of Physics and AstronomyKey Laboratory of Astroparticle Physics of Yunnan ProvinceYunnan UniversityKunming 650091China

Recently, a new radio millisecond pulsar(MSP) J1740-5340B, hosted in the globular cluster(GC) NGC 6397,was reported with a 5.78 ms spin period in an eclipsing binary system with a 1.97 days orbital period. Based on a modified radio ephemeris updated by tool tempo2, we analyze the ~15 yr γ-ray data obtained from the Large Area Telescope on board the Fermi Gamma-ray Space Telescope and detect PSR J1740-5340B's γ-ray pulsation at a confidence level of ~4σ with a weighted H-test value of ~26. By performing a phase-resolved analysis, the γ-ray luminosity in on-pulse interval of PSR J1740-5340B is L_(γ)~ 3.8 × 10^(33) erg s^(-1) using NGC 6397's distance of 2.48 kpc. And γ-rays from the on-pulse part of PSR J1740-5340B contribute ~90% of the total observed γ-ray emissions from NGC 6397. No significant γ-ray pulsation of another MSP J1740-5340A in the GC is *** that the previous four cases of MSPs in GCs, more data in γ-ray, X-ray, and radio are encouraged to finally confirm the γ-ray emissions from MSP J1740-5340B, especially starving for a precise ephemeris.

关键词： gamma-rays:galaxies (stars:)pulsars:individual(PSR J1740-5340B) (Galaxy:)globular clusters:individual(NGC 6397)

Effects of dietary Clostridium butyricum and rumen protected fat on meat quality,oxidative stability,and chemical composition of finishing goats

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Journal of Animal Science and Biotechnology 2024年第2期15卷 911-924页

作者： Meimei Zhang Zhiyue Zhang xinlong Zhang Changming Lu Wenzhu Yang Xiaolai Xie Hangshu xin Xiaotan Lu Mingbo Ni xinyue Yang Xiaoyang Lv Peixin jiao College of Animal Science and Technology Northeast Agricultural UniversityHarbin 150030People’s Republic of China Lethbridge Research and Development Centre Lethbridge T1J 4B1Canada School of Agriculture and Food Sciences The University of QueenslandGattonQLD 4343Australia International Joint Research Laboratory in Universities of Jiangsu Province of China for Domestic Animal Germplasm Resources and Genetic Improvement Yangzhou 225009China

Background Clostridium butyricum(CB)is a probiotic that can regulate intestinal microbial composition and improve meat *** protected fat(RPF)has been shown to increase the dietary energy density and provide essential fatty ***,it is still unknown whether dietary supplementation with CB and RPF exerts beneficial effects on growth performance and nutritional value of goat *** study aimed to investigate the effects of dietary CB and RPF supplementation on growth performance,meat quality,oxidative stability,and meat nutritional value of finishing ***-two goats(initial body weight,20.5±0.82 kg)were used in a completely randomized block design with a 2 RPF supplementation(0 vs.30 g/d)×2 CB supplementation(0 vs.1.0 g/d)factorial treatment *** experiment included a 14-d adaptation and 70-d data and sample collection *** goats were fed a diet consisted of 400 g/kg peanut seedling and 600 g/kg corn-based concentrate(dry matter basis).Result Interaction between CB and RPF was rarely observed on the variables measured,except that shear force was reduced(Pmuscular fat(IMF)content with adding RPF was more pronounced(P<0.05)with CB than without CB *** pH24h(P=0.009),a*values(P=0.007),total antioxidant capacity(P=0.050),glutathione peroxidase activities(P=0.006),concentrations of 18:3(P<0.001),20:5(P=0.003)and total polyunsaturated fatty acids(P=0.048)were increased,whereas the L*values(P<0.001),shear force(P=0.050)and malondialdehyde content(P=0.044)were decreased by adding ***,CB supplementation increased essential amino acid(P=0.027),flavor amino acid(P=0.010)and total amino acid contents(P=0.024)as well as upregulated the expression of lipoprotein lipase(P=0.034)and peroxisome proliferator-activated receptorγ(PPARγ)(P=0.012),and downregulated the expression of stearoyl-CoA desaturase(SCD)(P=0.034).The RPF supplementation increased dry

关键词： Chemical composition Clostridium butyricum Goats Meat quality Oxidative stability Rumen protected fat

Editing of eIF(iso)4E.c confers resistance against Turnip mosaic virus in Brassica rapa

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Horticultural Plant Journal 2024年第4期10卷 1020-1034页

作者： Yujia Liu Xiaoyun xin Peirong Li Weihong Wang Yangjun Yu Xiuyun Zhao Deshuang Zhang jiao Wang Fenglan Zhang Shujiang Zhang Shuancang Yu Tongbing Su State Key Laboratory of Vegetable Biobreeding Beijing Vegetable Research CenterBeijing Academy of Agriculture and Forestry ScienceBeijing 100097China National Engineering Research Center for Vegetables Beijing Key Laboratory of Vegetable Germplasms ImprovementKey Laboratory of Biology and Genetics Improvement of Horticultural Crops(North China)Key Laboratory of Urban Agriculture(North)of Ministry of AgricultureBeijing Vegetable Research CenterBeijing Academy of Agriculture and Forestry ScienceBeijing 100097China Institute of Vegetables and Flowers Chinese Academy of Agricultural SciencesBeijing 100081China

Turnip mosaic virus(TuMV)constitutes one of the primary diseases affecting Brassica rapa,severely impacting its production and resulting in crop failures in various regions *** research has demonstrated the significance of plant translation initiation factors,specifically the eIF4E and eIF4G family genes,as essential recessive disease resistance *** our study,we conducted evolutionary and gene expression studies,leading us to identify e IF(iso)4E.c as a potential TuMV-resistant *** CRISPR/Cas9 technology,we obtained mutant *** plants with edited eIF(iso)4E.c *** confirmed eIF(iso)4E.c confers resistance against TuMV through phenotypic observations and virus content ***,we employed ribosome profiling assays on eif(iso)4e.c mutant seedlings to unravel the translation landscape in response to ***,we observed a moderate correlation between the fold changes in gene expression at the transcriptional and translational levels(R^(2)=0.729).Comparative analysis of ribosome profiling and RNA-seq data revealed that plant-pathogen interaction,and MAPK signaling pathway-plant pathways were involved in eIF(iso)4E.c-mediated TuMV *** analysis revealed that sequence features,coding sequence length,and normalized minimal free energy,influenced the translation efficiency of *** study highlights that the loss of e IF(iso)4E.c can result in a highly intricate translation mechanism,acting synergistically with transcription to confer resistance against TuMV.

关键词： Brassica rapa eIF(iso)4E.c TuMV Ribo-seq

An axisymmetric characteristic model for enhancing prediction of centrifugal compressor characteristics

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Chinese Journal of Aeronautics 2024年第4期37卷 203-215页

作者： Peng REN Xiangjun FANG Zeyu jiao Ying HAN School of Energy and Power Engineering Beihang UniversityBeijing 100191China Guangdong Key Laboratory of Modern Control Technology Institute of Intelligent ManufacturingGuangdong Academy of SciencesGuangzhou 510070China

Rapid and accurate determination of compressor characteristic maps is essential for the initial design of centrifugal compressors in aircraft power systems. The accuracy of existing methodologies, which rely on combinations of loss models, varies significantly depending on the compressor's geometry and operational range. This variance necessitates substantial experimental or Computational Fluid Dynamics(CFD) data for coefficient calibration. To address this challenge, this study presents an axisymmetric characteristic model for compressor performance assessment. This model incorporates the factors of blade angle, meridional passage area, and the radial deflection angle of meridional streamlines of the compressor. These factors are derived from fundamental aerodynamic equations encompassing mass, momentum, and energy conservation of the compressor. In contrast to conventional one-dimensional approaches, the proposed method reduces the number of loss coefficients and more effectively accounts for the impact of geometric alterations on centrifugal compressor properties. Furthermore, the model reduces dependence on experimental and CFD data. Efficacy of the model is validated using experimental data from four distinct types of centrifugal compressors. Correlation analysis reveals that the model's coefficients can be expressed as functions of the ratio of the Reynolds number to the impeller tip speed. This ratio serves as a characteristic parameter for the design and optimization of centrifugal compressors. Consequently, the proposed method offers an efficient and accurate means for the quick computation of centrifugal compressor characteristics. This is of great significance for improving the efficiency of centrifugal compressors and reducing energy consumption.

关键词： Centrifugal compressor Positive problem Characteristic prediction Aerodynamic characteristic Axisymmetric model

Feedback Mechanism-driven mutation Reptile Search Algorithm for Optimizing Interpolation Developable Surfaces

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Journal of Bionic Engineering 2024年第1期21卷 527-571页

作者： Gang Hu jiao Wang Xiaoni Zhu muhammad Abbas Department of Applied Mathematics Xi'an University of TechnologyXi'an 710054China School of Mechanical and Precision Instrument Engineering Xi'an University of TechnologyXi'an 710048China Department of Mathematics University of SargodhaSargodha 40100Pakistan

Curvature lines are special and important curves on *** is of great significance to construct developable surface interpolated on curvature lines in engineering *** this paper,the shape optimization of generalized cubic ball developable surface interpolated on the curvature line is studied by using the improved reptile search ***,based on the curvature line of generalized cubic ball curve with shape adjustable,this paper gives the construction method of SGC-Ball developable surface interpolated on the ***,the feedback mechanism,adaptive parameters and mutation strategy are introduced into the reptile search algorithm,and the Feedback mechanism-driven improved reptile search algorithm effectively improves the solving *** IEEE congress on evolutionary computation 2014,2017,2019 and four engineering design problems,the feedback mechanism-driven improved reptile search algorithm is compared with other representative methods,and the result indicates that the solution performance of the feedback mechanism-driven improved reptile search algorithm is *** last,taking the minimum energy as the evaluation index,the shape optimization model of SGC-Ball interpolation developable surface is *** developable surface with the minimum energy is achieved with the help of the feedback mechanism-driven improved reptile search algorithm,and the comparison experiment verifies the superiority of the feedback mechanism-driven improved reptile search algorithm for the shape optimization problem.

关键词： Reptile search algorithm Feedback mechanism Adaptive parameter mutation strategy SGC-Ball interpolation developable surface Shape optimization

Smoothed-Particle Hydrodynamics Simulation of Ship Motion and Tank Sloshing under the Effect of Regular Waves

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Fluid Dynamics & Materials Processing 2024年第5期20卷 1045-1061页

作者： Mingming Zhao Jialong jiao School of Civil Engineering and Transportation South China University of TechnologyGuangzhou510641China

Predicting the response of liquefied natural gas(LNG)contained in vessels subjected to external waves is extremely important to ensure the safety of the transportation *** this study,the coupled behavior due to ship motion and liquid tank sloshing has been simulated by the Smoothed-Particle Hydrodynamics(SPH)***,the sloshing flow in a rectangular tank was simulated and the related loads were analyzed to verify and validate the accuracy of the present SPH ***,a three-dimensional simplified LNG carrier model,including two prismatic liquid tanks and a wave tank,was *** conditions were examined corresponding to different wave lengths,wave heights,wave heading angles,and tank loading ***,the effects of liquid tank loading rate on LNG ship motions and sloshing loading were analyzed,thereby showing that the SPH method can effectively provide useful indications for the design of liquid cargo ships.

关键词： LNG carrier tank sloshing seakeeping inner and external fluid coupling Smoothed Particle Hydrodynamics(SPH)

Advances in the differentiation of pluripotent stem cells into vascular cells

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World Journal of Stem Cells 2024年第2期16卷 137-150页

作者： Yi-Chang jiao Ying-xin Wang Wen-Zhu Liu Jing-Wen Xu Yu-Ying Zhao Chuan-Zhu Yan Fu-Chen Liu Department of Neurology Qilu Hospital of Shandong UniversityJinan 250012Shandong ProvinceChina Research Institute of Neuromuscular and Neurodegenerative Diseases Qilu Hospital of Shandong UniversityJinan 250012Shandong ProvinceChina Mitochondrial Medicine Laboratory Qilu Hospital(Qingdao)of Shandong UniversityQingdao 266103Shandong ProvinceChina Brain Science Research Institute Shandong UniversityJinan 250012Shandong ProvinceChina

Blood vessels constitute a closed pipe system distributed throughout the body,transporting blood from the heart to other organs and delivering metabolic waste products back to the lungs and *** in blood vessels are related to many disorders like stroke,myocardial infarction,aneurysm,and diabetes,which are important causes of death *** research for new appro-aches to disease modeling and effective treatment is needed due to the huge socio-economic burden on healthcare *** mice or rats have been widely used,applying data from animal studies to human-specific vascular physiology and pathology is *** rise of induced pluripotent stem cells(iPSCs)provides a reliable in vitro resource for disease modeling,regenerative medicine,and drug discovery because they carry all human genetic information and have the ability to directionally differentiate into any type of human *** review summarizes the latest progress from the establishment of iPSCs,the strategies for differentiating iPSCs into vascular cells,and the in vivo trans-plantation of these vascular *** also introduces the application of these technologies in disease modeling,drug screening,and regenerative ***,the application of high-tech tools,such as omics analysis and high-throughput sequencing,in this field is reviewed.

关键词： Induced pluripotent stem cell Blood vessels Vascular organoids Endothelial cells Smooth muscle cells Pericytes Tissue engineering vascular graft

Association of Cytokines with Clinical Indicators in Patients with Drug-Induced Liver Injury

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Biomedical and Environmental Sciences 2024年第5期37卷 494-502页

作者： CAO Wei Hua JIANG Ting Ting SHEN Ge DENG Wen WANG Shi Yu ZHANG Zi Yu LI xin xin LU Yao ZHANG Lu LIU Ru Yu CHANG Min WU Shu Ling GAO Yuan jiao HAO Hong Xiao CHEN Xiao Xue HU Lei Ping XU Meng jiao YI Wei XIE Yao LI Ming Hui Department of Hepatology Division 2 Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Department of Hepatology Division 2 Peking University Ditan Teaching HospitalBeijing 100015China Department of Gynecology and Obstetrics Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China

Objective To explore characteristics of clinical parameters and cytokines in patients with drug-induced liver injury(DILI)caused by different drugs and their correlation with clinical *** The study was conducted on patients who were up to Review of Uncertainties in Confidence Assessment for Medical Tests(RUCAM)scoring criteria and clinically diagnosed with *** on Chinese herbal medicine,cardiovascular drugs,non-steroidal anti-inflammatory drugs(NSAIDs),antiinfective drugs,and other drugs,patients were divided into five *** were measured by Luminex *** characteristics of clinical biochemical indicators and cytokines in DILI patients and their correlation were *** 73 patients were *** among five groups was statistically different(P=0.032).Alanine aminotransferase(ALT)(P=0.033)and aspartate aminotransferase(AST)(P=0.007)in NSAIDs group were higher than those in chinese herbal medicine ***-6(IL-6)and tumor necrosis factor alpha(TNF-α)in patients with Chinese herbal medicine(IL-6:P<0.001;TNF-α:P<0.001)and cardiovascular medicine(IL-6:P=0.020;TNF-α:P=0.001)were lower than those in NSAIDs *** was a positive correlation between ALT(r=0.697,P=0.025),AST(r=0.721,P=0.019),and IL-6 in NSAIDs *** Older age may be more prone to *** with NSAIDs have more severe liver damage in early stages of DILI,TNF-αand IL-6 may partake the inflammatory process of DILI.

关键词： Drug-induced liver injury Cytokines Non-steroidal anti-inflammatory drugs Inflammation