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Clinical and Bacteriological Profile of Infections in Sickle Cell Children in Two Referral Hospitals in Niamey, Niger

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Open Journal of Pediatrics 2024年第1期14卷 36-42页

作者： Kamaye Moumouni Samaila Aboubacar Garba Moumouni Georges Thomas Ibrahim Mamoudou Abdou Djafar Mamane Halima Hamadou Ibrahim Hamani Issaka Djibrilla Almoustapha Amadou Yacouba Abdourahamane Marou Soumana Boubacar moussa saley sahada Bade Malam Abdou Soumana Alido Service de Pédiatrie A H&#244pital National de Niamey Niamey Niger Faculté des Sciences de la Santé Université Abdou Moumouni de Niamey Niamey Niger Service de Pédiatrie H&#244pital national Amirou Boubacar Diallo Niamey Niger Service d’Onco-Hématologie H&#244pital national de Niamey Niamey Niger Service de Biologie Médicale H&#244pital national Amirou Boubacar Diallo Niamey Niger

Introduction: Infections are significant causes of mortality in sickle cell children in resource-limited countries. This study aimed to determine the clinical profile and bacterial ecology of infections in children with sickle-cell disease in two referral hospitals in Niamey. Patients and methods: A retrospective descriptive study was conducted from January 2018 to July 2020 in two referral hospitals in Niamey. All children aged one (1) to 15 years with sickle cell disease admitted for suspected infection, including at least one bacterial culture, were studied. Bacteriological analysis was performed using the appropriate culture media, using BactAlert (Reference 4700003 BTA3D60 BioMérieux). Results: Over 36-months, 350 children with a mean age of 10.9 months were admitted. The sex ratio was 1.2. The SS electrophoretic profile was the most common (93.4%). Immunization status was up to date in 66% of patients. Fever was the common reason for consultation (55.1%). Infection was confirmed in 62 patients (17.7%). The primary diagnoses were bacterial gastroenteritis (24.2%) and urinary tract infection (19.4%). Blood cultures were isolated from Salmonella typhi (13.0%) and Escherichia coli (8.7%). Klebsiella spp (7.1%) and Escherichia coli (5.0%) were detected in cytobacteriological examination of urine. Salmonella typhi (23.5%) and Escherichia coli (5.9%) were isolated on coproculture. Conclusion: Bacterial ecology appears not different from that usually observed in sickle-cell children. Salmonella and Escherichia coli were predominant.

关键词： Sickle Cell Disease Child Infection Niger

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Retinopathy Revealing Cerebral Venous Thrombosis in Sickle Cell Disease in Niger

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Open Journal of Ophthalmology 2019年第3期9卷 134-140页

作者： Nouhou Diori Adam Yacoubou Soumana saley Ali Amadou moussa Salia saley Idrissa Ophthalmology at the University of Lomé Lomé Togo Niamey Clinique Lumiere Lumiere Niger The General Reference Hospital of Niamey Niamey Niger Ophthalmology at the University Hospital Omar Drissi of Fez Morocco

Cerebral venous thrombosis (CVT) in sickle cell disease has been rarely described in the literature. Some authors consider sickle cell disease as a risk factor for CVT. We report the case of a 20-year-old boy, known as sickle cell, followed at the National Reference Center for Sickle Cell Disease in Niger. Admitted in consultation for a decrease of acuity with the right eye with perception of a black spot evolving since about three (3) days, ophthalmological examination revealed sickle cell retinopathy associated with cerebral venous thrombosis on MRI. The rest of the balance showed normochromic anemia, ionic disturbance and a D-dimer at 1500 μg/l. Rehydration, strict rest, antibiotic therapy and analgesics were started with an internal medicine opinion for further treatment. There was an improvement in visual acuity of 6/10 in 48 hours with disappearance of black spot perception, after three weeks, an ad integrum recovery of retinal lesions to control imaging. Despite the ocular complications of sickle cell disease involving visual prognosis, cerebral venous thrombosis is another complication to be investigated in any sickle cell retinopathy.

关键词： Sickle Cell Retinopathy Cerebral Venous Thrombosis Niger

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Dynamics and Vulnerability of Hydrogeomorphological Units to the Degradation of Climatic Conditions in the Watershed of the Birnin Lokoyo Pond (Iullemmeden Basin, Southwestern Niger)

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Journal of Environmental Protection 2022年第2期13卷 233-260页

作者： Karimou Dia Hantchi Bouba Hassane Habsatou Ousmane Faraâtou Issa saley Balla moussa Konaté Zibo Garba Department of Geology Faculty of Science and Techniques Dan Dicko Dankoulodo University Maradi Niger Department of Geology Faculty of Science and Techniques Abdou Moumouni University Niamey Niger Department of Digitization of Environmental Sciences Faculty of Science and Techniques University of Dosso Dosso Niger

The present study concerns the lowlands of the Birnin Lokoyo watershed located in the Matankari Rural Commune (Southwestern borders of the large Iullemmeden basin in the Niger). Dominated by the Birnin Lokoyo pond, this watershed faced with the continuous silting up of the minor bed, dissipates further upstream in the east, so that it moves downstream to the west for the benefit of the populations of Matankari city. The main objective of this work is to analyze the representative elements of the new climatic and environmental situation as well as the various factors determining the surface conditions in the watershed. The methodological approach is based on documentary research, field observations, individual surveys and interviews with targeted groups. The results show that the silting up of the lowlands is the result of the concomitant degradation of the plant cover and the soils, which, as a result, triggered the development of crusting surfaces and area erosion on the slopes. The study underlined the importance of endogenous knowledge in the choice of remedies against the silting up of lowlands. In addition, rational land management practices on plateaus and structures (within the watershed) do not seem to be in phase with topographical factors and the tectonic framework. This work is part of the vision of better management of glacis on the banks, but also of sills subject to regressive erosion upstream and in order to guide the policies of resilience of the populations.

关键词： Niger Birnin Lokoyo Wetlands Hydroclimatic Variability Soil

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Geology, Mineralogy and Geochemistry of the Oligocene Oolitic Iron Ore of the Continental Terminal Formation, Kandi Basin, North-East Benin

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International Journal of Geosciences 2019年第4期10卷 491-512页

作者： Adiss Kamal Issifou Fatiou moussa Konaté Soulémana Yessoufou Cossi Luc Adissin Glodji Matthias Heckmann Hamidou Garba saley Department of Geology Groundwater and Georesources Laboratory Faculty of Sciences and Technology Abdou Moumouni University of Niamey Niamey Niger Department of Earth Sciences Laboratory of Geology Mines and Environment Faculty of Sciences and Technology University of Abomey-Calavi Abomey-Calavi Benin Federal Institute for Geosciences and Natural Resources (BGR) Hannover Germany

The Oligocene Continental Terminal Formation of the Kandi Basin contains high grades of iron mineralization (~56.72% Total Fe). The microscopic study under the polarized and reflected light showed that the iron ore consists of silicate minerals (quartz 50% and zircon 1%) and non-silicate minerals (goethite 30%, hematite 7%, magnetite 3%, pyrite 1%, chalcopyrite 1%, blende 3%, galena 3%, scheelite 1% and gold 2%). The X-rays fluorescence shows that the iron ore is characterized by various elements, such as Fe2O3 (57.91% to 91.33%), SiO2 (3.07% to 33.19%), aluminum (2.94% to 7.74%), vanadium (0.04% to 0.11%), phosphorus (0.79% to 2.29%) and sulfur (<0.3%). The deleterious elements grade is above the permissible limit in metallurgy (0.05% - 0.07% for phosphorus and 0.1% for sulfur). Their high grades indicate that the Kandi Basin iron ore characteristics are not favorable for steel manufacturing despite its good vanadium contents (0.04% to 0.11%). However, it could be used for the cast iron manufacture. Spectrometric analysis by atomic absorption confirms the presence of low-grade gold associated to the iron ore (from 0.006 to 0.015 ppm). The comparative study of discontinuous stratiform iron ore of the Kandi Basin with other oolitic iron ores in exploitation from other countries such as Brazil, Australia, China, Russia, Uganda and the United States shows that iron ore of the Kandi Basin can be mined despite its high silica content.

关键词： Kandi Basin Oolitic Iron Ore Continental Terminal Formation

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The Projected Changes of Precipitations over Niger Under the Scenarios RCP 4.5 and RCP 8.5

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Journal of Environmental Science and Engineering(B) 2022年第6期11卷 248-266页

作者： Mounkaila saley moussa Yacoubou Mahamadou Abdou saley Inoussa Department of Physics Faculty of Sciences and TechniquesAbdou Moumouni UniversityBP:10662NiameyNiger Department of Physics Faculty of Sciences of EducationAndre Salifou UniversityBP:656ZinderNiger

The socio-economic activities of Niger rely on agriculture which is strongly affected by changes in precipitation during the rainy *** ultimate aim of this study is to assess the projected changes of precipitation over Niger under the Representative Concentration Pathways(RCP)scenarios 4.5(RCP 4.5)and RCP 8.5 using multi-RCM(Multi-Regional Climate)model *** observation data are from CHIRPS(Climate Hazards Group InfraRed Precipitation with Station)and the RCMs are from the SMHI(Swedish Meteorological and Hydrological Institute)model(RCA4)driven by ten(10)different GCMs(General Circulation Model)(e.g.,CCCma,CSIRO,ICHEC,IPSL,MIROC,MOHC-HadGEM2,MPI,NCC-NorESM1,NOOA,and NRCM)within the framework of CORDEX(Coordinated Regional Climate Downscaling Experiment)Africa *** reference and projections periods in this study are respectively 1981-2005 for the present and 2011-2100 for the near,medium and far future divided into three periods,2011 to 2040(P1),2041 to 2070(P2)and 2071 to 2100(P3).The methodology used,consists of assessing the performance of the multi-RCMs of RCA4 model(with respect of CHIRPS)in simulating the precipitations changes by computing the spatial distribution and anomalies of precipitations;and their indices of RMSE(Root Mean Square Error),the bias,SPI(Standardized Precipitation Anomaly Index),correlation coefficient,statistical t-test,spatial evolution rate and the rate of temporal *** the validation of the multi-RCMs RCA4 models,the ensemble mean of the models is used to assess the projected changes of precipitations over Niger in the *** results show that most of the multi-RCMs capture the four climatic zone except for *** the ensemble mean of the models simulates(as compared to CHIRPS)more accurately the monthly,annual precipitations anomalies and their indices than individual’s models in the reference period,some RCMs(e.g.,CSIRO-IPSL and CCCma-HadGEM)poorly reproduce *** projected changes of precip

关键词： Climate projection precipitation changes anomaly scenarios RCP Niger Sahel

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