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Open Journal of Obstetrics and Gynecology 2017年第2期7卷 235-244页

作者： Jean Marc Lamine Dia Eric Bohoussou Edouard Nguessan mouhideen oyelade Privat Guié Simplice Anongba Gynecology Obstetrics University Hospital of Treichville Abidjan C&ocirc te d’Ivoire

Objectives: This study aimed to clarify the etiology of women infertility and describe their management in our service with limited technical equipment. Methodology: We conducted a retrospective and descriptive study on 175 women treated for infertility and followed in the gynecology services of the university Hospital center of Treichville from 1st January 2012 to 31st December 2014. Results: During the study, we recorded 12072 consultations in gynecology including 1582 (13.1%) cases of infertility, but only 175 cases were selected for this study. The patients had an average age of 31.3 years and an average socio-economic level in general (78.9%). The etiologies were found in 79.4% of patients, dominated by classical abnormalities: uterine (fibroids: 41.8%), hormonal, tubo peritoneal (5%). We also found some unusual pathologies related to cultural practices (female genital mutilation, caustic stenosis of the vagina). The surgery was performed in several patients, including myomectomy by laparotomy (46.6%), laparoscopy, hysteroscopy and vaginal surgeries. As to drug treatment, they were various combinations, and the ovarian stimulation practices (62.3%) and induction of ovulation (47.2%) were common. The result of this support has been marked by the occurrence of 74 pregnancies (42.3%), with the birth of healthy children in the majority of cases (95.9%). Conclusion: The management of infertile women was frequent and yielded encouraging results despite our limited technical equipment.

关键词： Women Infertility Etiologies Treatment

Mother-to-Child HIV Transmission Factors in Exposed Children at University Hospital Center of Treichville (Abidjan, Cote d’Ivoire)

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Open Journal of Obstetrics and Gynecology 2017年第12期7卷 1198-1208页

作者： Edouard N’Guessan Jean Marc Lamine Dia mouhideen oyelade Ignace Yao Privat Guié Simplice Anongba Department of Obstetrics and Gynecology University Hospital of Treichville Abidjan Cote d’Ivoire

Background: The elimination of HIV transmission from mother to child is currently possible. Cote d’Ivoire, which has a 4.6% HIV prevalence among women, is one of 22 pilot countries for the elimination of mother-to-child transmission of HIV. Since 2015, Cote d’Ivoire has adopted new strategies according to the WHO B+ guidelines. Objective: To identify factors associated with mother-to-child HIV transmission in children born of seropositive mothers managed at Treichville university hospital. Material and methods: A case-control study was conducted in the obstetrics department at Treichville university hospital, between January 2013 and December 2015. It involved children born to mothers infected with HIV, whose first PCR (Polymerase Chain Reaction) result was available during this period. A standardized questionnaire on data related to exposed children and their mother was used. Factors associated with mother-to-child HIV transmission were investigated using logistic regression. Results: A total of 214 HIV-exposed children were included in the study with a sex ratio of 0.9. The majority of the children were born by vaginal route (52.8%) and received post-exposure prophylaxis (88.3%) and replacement feed (51.9%). Their mothers received antiretroviral therapy during pregnancy in 45.3% of the cases. The first PCR was performed at the sixth week of life in 52.3% of cases. The prevalence of HIV infection in exposed children was 7.5% (95% CI = 4.5% - 11.8%). In multivariate analysis, the absence of antiretroviral prophylaxis in children [aOR = 4.3, 95% (1.2 to 15.6), p = 0.03], the mixed feed [aOR = 3.8, 95% (1.1 - 13.1), p < 0.03], the failure to take antiretroviral regimen during pregnancy [aOR = 8.0, 95% CI (1.9 - 32.4), p < 0.003], were associated with mother-child HIV transmission. Conclusion: The mother-to-child HIV transmission rate remains high in our practice. Strategies to reduce situations that do not comply with current recommendations should be considered to pr

关键词： HIV-Exposed Children Mother-to-Child Transmission DBS/PCR

Occurrence Delays of Metastatic Relapses of Breast Cancers Treated at University Hospital of Treichville (Abidjan-Cote d’Ivoire)

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Journal of Cancer Therapy 2017年第11期8卷 924-932页

作者： Lydie Estelle Djanhan Jean Marc Dia Boston Mian mouhideen oyelade Aboulaye Diallo Privat Guié Simplice Anongba Department of Gynecology and Obstetrics University Hospital of Bouaké Bouake Cote d’Ivoire Department of Gynecology and Obstetrics University Hospital of Treichville Abidjan Cote d’Ivoire Department of Gynecology and Obstetrics University Hospital of Cocody Abidjan Cote d’Ivoire

Objective: Describe the occurrence delays of metastatic relapses of breast cancer based on the characteristics of the original tumor. Methodology: This is a retrospective and cohort study conducted from January 2000 to December 2015 on patients with metastatic relapse of breast cancer. Results: Out of 178 patients collected, the metastatic relapses were estimated at 49%, occurring in patients with an average age of 53.4 years. The majority of the patients was educated (91.6%) and did not have a high socioeconomic level (88.2%). The initial tumors were mainly at a clinical stage III (47.8%), SBR grade III (47.2%), high index Ki 67 (46.5%), negative RH (79.3%) and HER2 negative (58%). Metastases were unique in general (62.9%), dominated by bone locations (36.6%), with an average age of occurrence of 2.4 years. After the occurrence of these metastases, the cumulative survival rate was 5% at 3 years, and zero to 5 years. Conclusion: Metastatic relapses were common with poor prognosis.

关键词： Breast Cancer Risk Factors Metastatic Relapses

Breast Cancers in Young Woman under 40 Years in Sub-Saharan Africa: Experience of the Gynecology Department of the University and Hospital Center of Treichville (Abidjan—Cote d’Ivoire)

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Journal of Cancer Therapy 2017年第8期8卷 714-725页

作者： Jean Marc Dia Moctar Touré Ignace Yao Eric Bohoussou Corneil Saki mouhideen oyelade Gérard Okon Simplice Anongba Gynecology Department of the University and Hospital Center of Treichville (CHUT) Abidjan C&ocirc te d’Ivoire Cancerology Department of the University and Hospital Center of Treichville (CHUT) Abidjan C&ocirc te d’Ivoire

Objective: To describe the epidemiological, clinical and therapeutic characteristics of women under 40 years followed for breast cancer. Method: This is a retrospective and cohort study with descriptive purpose conducted over 10 years on the management of breast cancer in 105 patients under 40 years in the Gynecology Service of the University and Hospital Center of Treichville. Results: The incidence of breast cancer in women under 40 years was 8.4%, and the majority of patients were over 35 years old (64.8%) and had a low socioeconomic level (61.7%). Some patients had classic risk factors for breast cancer: menarche before 12 years (48.6%), nulliparity (20%), family history of breast cancer (1.9%). The discovery of a breast abnormality was made by patients in 97.1% of the cases. Cancers were either isolated (92.4%) or associated with pregnancy (5.7%) or bilateral (1.9%). The majority of cancers were infiltrating ductal carcinomas (86.7%), of SBR II grade (69%). Patients generally benefited from a mastectomy with axillary dissection, framed by chemotherapy. The global survival at 10 years was 5%. Conclusion: This study allowed us to confirm that breast cancers in younger women were a reality in our country and posed us enormous difficulties in their management.

关键词： Breast Cancer Young Women Diagnosis Treatment

Ovarian Pregnancy: Diagnosis and Management of a Rare Case of Ectopic Pregnancy

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Open Journal of Obstetrics and Gynecology 2024年第11期14卷 1671-1678页

作者： Gerard Okon Roland Adjoby Stephane Kume Corneille Saki Fahimat Tijani Abdoulaye Diallo mouhideen oyelade Aude-Lima Djiro Isaac Kouamé Dominique N’Zi Youssouf Diabaté Eric Bohoussou Privat Guié Gynecology Department of the University and Hospital Center of Treichville (CHUT) Abidjan Cte dIvoire Gynecology Department of the University and Hospital Center of Angr (CHUA) Abidjan Cte dIvoire

Ectopic pregnancy (EP) is a common gynecological emergency, with ovarian pregnancy (OP) being a rare form, representing about 3% of EP cases. OP poses diagnostic and therapeutic challenges due to its often-asymptomatic progression and nonspecific clinical presentation. We report the case of a 32-year-old primiparous woman diagnosed with an ovarian pregnancy by ultrasound. The patient frequently used emergency contraceptives and presented with intermittent pelvic pain and secondary amenorrhea with positive urinary β-HCG tests. Ultrasound revealed a lateral uterine gestational sac attached to the left ovary, containing a living fetus of 15 weeks + 6 days, with moderate fluid accumulation. Upon admission, the patient was in shock with severe anemia and hemoperitoneum, necessitating emergency laparotomy. The laparotomy revealed a hemoperitoneum of 1400 mL and a hyper vascularized mass involving the left ovary, requiring left adnexectomy. The mass contained a deceased male fetus of 16 weeks. This case highlights the need for heightened vigilance and precise diagnostic and therapeutic approaches for rare forms of EP to prevent severe complications.

关键词： Ovarian Pregnancy Ultrasound Diagnosis Surgical Complications

Epidemiological Aspects of Metastatic Relapse of Breast Cancer in an African Context

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Open Journal of Obstetrics and Gynecology 2017年第5期7卷 552-561页

作者： Jean Marc Dia Corneille Saki Oyeladé mouhideen Eric Bohoussou Moctar Touré Gerard Okon Privat Guié Simplice Anongba Gynecology Department of the University and Hospital Center of Treichville (CHUT) Abidjan C&ocirc te d’Ivoire Cancerology Department of the University and Hospital Center of Treichville (CHUT) Abidjan C&ocirc te d’Ivoire

Objectives: This study aimed to describe the epidemiological characteristics of metastatic relapse in breast cancer at the University and Hospital Center of Treichville. Methodology: This is a cohort and retrospective study conducted from January 2000 to December 2015 on 178 patients with metastaticrelapse in breast cancer. Results: The prevalence of metastatic relapses was 49% and the patients had an average age of 53.4 years and among them, 91.6% received school education and 88.2% did not have a high socioeconomic level. The majority of initial tumors were in Stage III (47.8%), SBR III (47.2%), High Ki 67 (46.5%), Negative RH (79.3%), and HER2 negative (58%). Metastases were generally unique (62.9%), dominated by bone sites (36.6%), with an average occurrencedelay of 2.4 years. After the occurrence of metastases, the cumulative survival rate was 5% at 3 years, and nil at 5 years. Conclusion: Metastatic relapses were common with poor prognosis.

关键词： Breast Cancer Risk Factors Metastatic Relapses

Management of Inflammatory Breast Cancers in Subsaharian Africa Context

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Open Journal of Obstetrics and Gynecology 2018年第1期8卷 20-30页

作者： Jean Marc Dia Lydie Estelle Djanhan C. Saki mouhideen Oyéladé Gérard Okon Abdoulaye Camara Abdoulaye Diallo Privat Guié Simplice Anongba Department of Gynecology and Obstetrics University Hospital of Treichville Abidjan Cote d’Ivoire Department of Gynecology and Obstetrics University Hospital of Bouaké Bouake Cote d’Ivoire

Objective: To report the experience of Gynecology Department of the University Hospital of Treichville in the management of the inflammatory breast cancers. Methodology: We conducted a retrospective and descriptive study on cases of the inflammatory breast cancers managed in the Gynecology Department of the University Hospital of Treichville, from January 2011 to December 2015. Results: We collected 44 cases of inflammatory breast cancer representing 17.9% of all breast cancers. The average age of patients was 46.5 years (32 - 70 years) and among them, the majority had inadequate socioeconomic level (90.9%). The risk factor for cancer found in the majority of patients was the age of first menstrual periods before the age of 12 years (52.3%). The average consultation time was long (10 months) and several patients had extensive inflammatory signs (38.6%), with lymph node involvement (84.1%) and metastases (36.4%). At the histological analysis, the most common type was invasive ductal carcinoma (81.8%), SBR grade III (54.5%). Regarding treatment, mastectomy according to Patey associated with a chemotherapy was performed in 22.7% cases. The evolution has been marked by an overall 5-year survival of 20%. Conclusion: The management of inflammatory breast cancers was late and incomplete in our service making poor prognosis.

关键词： Inflammatory Brest Cancers Epidemiology Diagnosis Treatment