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Ischemic Stroke Revealing Infective Endocarditis in a Young Subject: About a Clinical Case

World Journal of Cardiovascular Diseases 2022年第4期12卷 209-215页

作者： Coumba Thiam Boubacar Sonfo Massama Konaté Mahan Ameri Abba Diall Asmaou Keita Mariam Sako Youssouf camara Hamidou Oumar Bâ Ibrahima Sangaré Mamadou Touré Samba Sidibé Massama camara Simo Moyo Souleymane Coulibaly Ichaka Menta Cardiology Department of Kati University Hospital Kati Mali Internal Medicine Department of Mali Hospital Bamako Mali Cardiology Department of the Mother-Child University Hospital Bamako Mali Cardiology Department CHU Point G Bamako Mali Cardiology Department of the CHU Gabriel Touré Bamako Mali

Introduction: Neurological complications are possible during infective endocarditis. They are often life-threatening and can be a source of sequelae. Case Presentation: We report the case of an 11-year-old patient admitted to the cardiology department of the CHU-ME “LUXEMBOURG” in Bamako for functional impotence of the left hemibody, accompanied by fever and NYHA stage II dyspnea. The clinical examination on admission shows the poor general condition, normal consciousness, and sensory-motor deficit of the pyramidal type of the left hemibody. The cardiovascular examination notes a systolic murmur at the mitral focus, hepato-jugular reflux, hepatomegaly, and slight edema in the lower limbs. Brain CT showed localized hypodensity in favor of an ischemic stroke. The electrocardiogram shows a sinus rhythm. Transthoracic Doppler echocardiography revealed mitral insufficiency with vegetation of 17 × 14 mm on the anterior mitral valve, with left ventricular ejection fraction estimated at 75%. Dual antibiotic therapy associated with conventional treatment for heart failure was initiated. The clinical evolution was marked by the persistence of the deficit of the left upper limb, the cardiac Doppler echography of control after 6 weeks of treatment found the same vegetation. A discussion with the heart team with a view to a surgical cure has been initiated for the rest of the treatment. Conclusion: A motor deficit associated with fever related to an ischemic vascular accident should lead to a search for infective endocarditis on cardiac Doppler ultrasound.

关键词： Ischemic Stroke-Infectious Endocarditis-Young Subject

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Right Internal Jugular Vein Ectasia in African Woman: A Report of 2 Cases

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Surgical Science 2015年第10期6卷 437-441页

作者： Seydou Togo Moussa Abdoulaye Ouattara Sékou Koumaré Mody Abdoulaye camara Sadio Yena Thoracic and Vascular Surgery Department Hospital of Mali Bamako Mali Surgery “A” Department Point G Hospital Bamako Mali Radiology Department Hospital of Mali Bamako Mali

Internal jugular vein (IJV) ectasia is a rare benign disease. It commonly presents as a unilateral, soft, compressible neck swelling that mostly involves the right side. It is usually a childhood disease and believed to be of congenital origin. Accurate diagnosis from careful history, physical examination and radiological study can be made. We report here two cases of IJV ectasia in African adults with right lateral neck mass dilating when increase intrathoracic pressure. Because of its rarity, this entity is frequently ignored or misdiagnosed. This case report intends to stress the importance of keeping IJV ectasia as differential diagnosis in mind in case of lateral neck swellings to avoid invasive investigations and inappropriate treatment. The asymptomatic case management of IJV ectasia is conservative with long-term surveillance.

关键词： Jugular Vein Ectasia Adults Management

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Seroprevalence of Human Immunodeficiency Virus and Hepatitis B in Blood Donors at the N’Zérékoré Regional Blood Transfusion Centre in Guinea

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Open Journal of Immunology 2024年第2期14卷 33-45页

作者： Alimou camara Ernest Thea Ives Nyankoye Haba Yamoussa Youla Ibrahima Sory Diallo Mariama Sadio Diallo Djiba Kaba Jacob camara Moussa Condé Barré Soropogui Kaba Kourouma Thierno Mamadou Tounkara Babacar Mbengue Abdoulaye Touré Sanaba Boumbaly Virology Research Centre Guinea Viral Haemorrhagic Fevers Laboratory Conakry Guinea Faculty of Health Sciences and Techniques Gamal Abdel Nasser University Conakry Guinea National Blood Transfusion Centre Ministry of Health and Public Hygiene Conakry Guinea Institute of Health and Childhood Donka National Hospital Conakry Guinea African Centre of Excellence for the Prevention and Control of Communicable Diseases Conakry Guinea Department of Dermatology and Venereology Donka University Hospital Conakry Guine Immunology Laboratory Cheikh Anta Diop University Dakar Senegal Centre for Research and Training in Infectious Diseases of Guinea Conakry Guinea

Blood transfusion saves lives and reduces morbidity and mortality for a large number of diseases and clinical conditions, but it is not without danger. The aim of this study was to determine the seroprevalence of HIV and hepatitis B in blood donors received at the regional Blood Transfusion Centre of N’Zérékoré (Guinea). This was a 5-year retrospective analytical study. We included records of blood donors aged 18 to 60 years admitted to the N’Zérékoré Regional Blood Transfusion Centre for blood donation from January 2016 to December 2020. We performed a descriptive analysis followed by Chi-2 or Fish-er-exact tests and the Student or Wilcoxon test, followed by multivariate logistic regression. In this study, donor age ranged from 18 - 60 years, with a pre-dominance of donors aged 25 - 34 (44.2%). Male donors were the most represented in our study (79.0% versus 21.0% female). More than half of the donors were blood group O (55.6%). We observed a seroprevalence of 3.6% for HIV, 13.4% for HBsAg and 0.2% for co-infection. In our series, age 25 - 34 (OR = 1.89 and P = 0.001) and 35 - 44 for HIV (OR = 2.01 and P = 0.001), HBsAgserostatus (OR = 3.04 and P = 0.001) and blood donation history (OR of 3.04 and P = 0.001) were factors associated with HIV positivity (P < 0.05). In our study, HIV serostatus (OR = 3.04 and P = 0.001) and blood donation history (OR = 0.01 and P = 0.001) were factors associated with HBsAgseropositivity. We reported a high prevalence of HIV and HBsAg. Sex, serological status and blood donation history were associated factors.

关键词： Seroprevalence HIV Hepatitis B Blood Donors N’Zérékoré Guinea

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Old game, new players: Linking classical theories to new trends in transplant immunology

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World Journal of Transplantation 2017年第1期7卷 1-25页

作者： Marina Burgos da Silva Flavia Franco da Cunha Fernanda Fernandes Terra Niels Olsen Saraiva camara Department of Immunology Institute of Biomedical Sciences University of S?o Paulo Nephrology Division Department of Medicine Federal University of S?o Paulo Renal Pathophysiology Laboratory Faculty of Medicine University of S?o Paulo

The evolutionary emergence of an efficient immune system has a fundamental role in our survival against pathogenic attacks. Nevertheless, this same protective mechanism may also establish a negative consequence in the setting of disorders such as autoimmunity and transplant rejection. In light of the latter, although research has long uncovered main concepts of allogeneic recognition, immune rejection is still the main obstacle to long-term graft survival. Therefore, in order to define effective therapies that prolong graft viability, it is essential that we understand the underlying mediators and mechanisms that participate in transplant rejection. This multifaceted process is characterized by diverse cellular and humoral participants with innate and adaptive functions that can determine the type of rejection or promote graft acceptance. Although a number of mediators of graft recognition have been described in traditional immunology, recent studies indicate that defining rigid roles for certain immune cells and factors may be more complicated than originally conceived. Current research has also targeted specific cells and drugs that regulate immune activation and induce tolerance. This review will give a broad view of the most recent understanding of the allogeneic inflammatory/tolerogenic response and current insights into cellular and drug therapies that modulate immune activation that may prove to be useful in the induction of tolerance in the clinical setting.

关键词： Transplant immunology Immune rejection Inflammation Adaptive immunity Innate immunity Graft tolerance

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From Fostering to Delusional Disorder of Filiation

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Open Journal of Psychiatry 2024年第4期14卷 283-286页

作者： Momar camara Wissem Masmoudi El Hadji Makhtar Ba Sokhna Seck Maïmouna Dieye Aïda Sylla Department of Psychiatry and Medical Psychology Cheikh Anta Diop University Dakar Senegal Thiaroye National Psychiatric Hospital Center Dakar Senegal Fann National University Hospital Center Dakar Senegal Albert Royer Childrens Hospital Dakar Senegal

Introduction: Fostering is a widespread practice in West Africa. It played an essential role in the circulation of children. The failure of its community regulation, not compensated by a legal framework, has made its practice precarious. Observation: A case study was conducted on Dior, who was hospitalised in a psychiatric ward for a delusional disorder of filiation. Dior was entrusted to her maternal grandmother and aunt at ages 2 and 9. During these fosterings, the place of the symbolic father was not substituted, causing a void that challenged her imagination. The outcome was an inscription in a genealogy where she had found herself with prestigious parents. Discussion: Fostering has strongly disrupted the family dynamics in Dior’s case. One of her options was to assume the paternal function, the use of which was perceived as a defiance or even a transgression. This same function would be a starting point of a psychosis whose filial character would only be an attempt at rectification where reality and imagination collide. Conclusion: Our study reveals the importance of stable parental figures at stake in fostering contexts, which constitute a risk factor for the development of a subsequent psychosis.

关键词： Delusional Disorder of Filiation Psychopathology Interactions Fostering Family

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Monitoring of the Physico-Chemical Parameters of the Waters of Lake Sonfonia,Municipality of Ratoma(Republic of Guinea)2021

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Journal of Environmental Science and Engineering(B) 2023年第3期12卷 105-114页

作者： Mohamed Lamine Komara Adama Moussa Sacko Aboubacar Diallo Cheick Ahmed Tawel camara Mamadou Kabirou Bah Teacher-Researcher Department of Biology Gamal Abdel Nasser University of Conakry Republic of Guinea Laboratory technique Higher Institute of Technology of MamouRepublic of Guinea DGA-Research/ISAU Conakry 324 Republic of Guinea Director of the Biochemistry degree program at Gamal Abdel Nasser University of Conakry Republic of Guinea Center for Environmental Studies and Research(CERE) Conakry 324 Republic of Guinea

As part of the determination of the possible impact of human activities on surface waters, case of Lake Sonfonia, six sampling sites were selected according to their solicitation by the population and their exposure to probable sources of pollution. The objective of this work is to monitor the physico-chemical quality of the waters of Lake Sonfonia during the low water level (March) and during the flood period (August) of the year 2021. Two sampling campaigns of water were carried out in dry weather and two others in cold weather. Parameters such as temperature, pH, EC (Electrical Conductivity), dissolved oxygen, TDS (Total Dissolved Solids) were measured in situ. Suspended matter, phosphate, nitrate, nitrite, sulphates, total iron, COD (Chemical Oxygen Demand) were measured in the laboratory by the colorimetric method. Stata 15 software was applied for the statistical analysis of the data and the correlation test between the parameters gave highly significant correlations. It has been noted that the situation is not very good and that this pollution comes mainly from human activities.

关键词： Surface water physico-chemical parameters Lake Sonfonia anthropogenic eutrophication.

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Sustainable Management of Biodegradable Waste in Guinea: Effect of Compost on Eggplant and Chilli Crop Yields Pepper

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Agricultural Sciences 2024年第9期15卷 1009-1017页

作者： Mamadou Yaya Baldé Mamadou Aliou Diallo Mariama Barry Dian Foula Diallo Mamadouba Bangaly camara Nyankoï Soropogui Institut de Recherche Environnementale de Guine (IREG) Conakry Guinea Department of Chemistry Gamal Abdel Nasser University of Conakry Conakry Guinea

The fight against insalubrity in large urban and peri-urban agglomerations is a major challenge in developing countries. This problem is compounded by that of sustainable waste management mechanisms. Indeed, the current waste collection system in Guinea has proved inadequate, as moving garbage from point “A” to point “B” is tantamount to “moving the problem”. The aim of this experimental work is to demonstrate the cost-effectiveness and benefits of sustainable waste management. As part of this drive to valorize biodegradable waste, the Waste Management Research Center has undertaken a series of activities ranging from composting organic waste to testing compost on certain crop varieties. An experimental field of 8024 m2 was laid out and treated with 1500 Kg of fine compost in doses ranging from 2.5 to 5 T/ha. Two crop varieties, eggplant and chili, were tested. Compost application increased production yields: 15 to 21 tonnes of eggplant and 10.4 to 11.1 tonnes of chili per hectare. Growth rates compared with usual yields varied from 50% to 64% and from 11% to 17% for eggplant and chili, respectively. This study resulted in an optimum compost dose of 2.5 T/ha for this phase.

关键词： Sustainable Waste Management Compost Eggplant Chilli Yield IREG CREGED

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Physico-Chemical Studies of the Bricks in Mud Raw Used in the Construction of Century-Old Huts(Straw Huts):Case of the Urban Commune of Kouroussa

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Journal of Environmental Science and Engineering(A) 2023年第6期12卷 201-213页

作者： Mamady Kourouma Adama Moussa Sakho Aboubacar Diallo Mamadou Madaniou Sow Abdoulaye Ibrahim camara Mamoudou Conté Department of Chemistry Gamal Abdel Nasser University of ConakryConakry 1147Republic of Guinea Department of Laboratory Techniques Higher Institute of Technology of MamouMamou 063 MamouRepublic of Guinea Higher Institute of Architecture and Town Planning Conakry 324Republic of Guinea of Guinea Department of Building Materials Scientific research center of Conakry-Rogbane 1615 Republic of Guinea of Guinea

Building construction using cement bricks on the one hand,and mud bricks on the other hand,presents problems of resistance and durability in the face of natural weathering in our country(Republic of Guinea).These difficulties could be linked to non-compliance with standards and the failure to master certain physico-chemical,mechanical and technical parameters when constructing a *** order to remedy this problem,a series of studies were carried out on samples of mud bricks used in the construction of century-old straw hut buildings in the urban commune of Kouroussa(Republic of Guinea).To this end,the compressive strength of the brick samples was assessed either:0.10 MPa,and sensory techniques of certain characteristics were carried out to evaluate the cohesion of the elements in the brick samples,such as:coward boule technique,hand washing test,withdrawal of a soil(pellet or ring test)and of the jar *** physico-chemical analyses methods were carried out using XRF(X-Ray Fluorescence Spectrometry),granulometry and Atterberg limits in accordance with NF P *** results showed a high insoluble residue content(49.9%)and the sample had a clay-like appearance with a low PI(Plasticity Index)=8%.This study could be an alternative guide for the authorities in charge of housing and construction in the Kouroussa prefecture(Republic of Guinea).because,the majority of houses in Upper Guinea are built with mud raw bricks or fired bricks.

关键词： Century-old in straw hut building raw earth brick resistance durability

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Penile Cancer in Liberia: A Case Report and Review of the Literature

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Health 2018年第8期10卷 1132-1139页

作者： Edet Ikpi Solomane Konneh Bashir Yunusa Ansumana camara Alberta Clark Sean Subah David Alele Monica Sroden Urology Division Department of Surgery JFK Memorial Hospital Monrovia Republic of Liberia Department of Surgery Icahn School of Medicine Mount Sinai New York USA Department of Pathology Waterbury Hospital Waterbury USA

Background: Penile cancer is uncommon in Liberia with no record of its occurrence so far in the literature. Its occurrence worldwide is significantly affected by cultural or religious practices like childhood circumcision. Smoking, poor penile hygiene and inflammatory processes in the presence of smegma increase the risk of its occurrence. Objective: To review the first case of penile cancer treated in Liberia. Materials and Method: Case report. Case Presentation/Report: Our index patient is a 65-year old man referred from a peripheral centre in acute urinary retention. He also presented with a year history of progressively expanding ulcerative penile lesion affecting the glans and penile shaft. Local examination of the genitalia revealed an ulcerated lesion extending from the glans up to the mid shaft of the penis. The penobulbar urethra was free of induration. The external urethral meatus was infiltrated by the lesion. The scrotum and testes were normal and digital rectal examination revealed a moderately enlarged benign prostate. Bilateral inguinal lymph node enlargement was elicited. A diagnosis of advanced penile cancer with benign prostatic hyperplasia was made. The patient had partial penectomy, reconstruction of new external urethral meatus and inguinal lymphadenectomy. The specimen was histologically confirmed to be Squamous cell Carcinoma of the penis;the resection margins and lymph nodes biopsied were found to be adequate and tumor free respectively. Patient’s post operative recovery was uneventful and he was discharged after a week. His follow up status after 6 months has remained satisfactory. Conclusion: Though rare, penile cancer does occur in Liberia and specialist staff with capacity for diagnosing and surgical intervention remains critical to patients’ outcome. Early intervention improves the chances of better outcome;counseling is critical to prevent treated patient lapsing into depression.

关键词： Carcinoma Penis Penectomy

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Obesity in kidney disease:A heavyweight opponen

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World Journal of Nephrology 2014年第3期3卷 50-63页

作者： Raphael Jose Ferreira Felizardo Marina Burgos da Silva Cristhiane Favero Aguiar Niels Olsen Saraiva camara Department of Medicine Nephrology DivisionFederal University of Sao PauloSao Paulo 04039-032Brazil Department of Immunology Institute of Biomedical SciencesUniversity of Sao PauloSao Paulo 05508-900Brazil

Obesity is an important worldwide challenge that must be faced in most developed and developing countries because of unhealthy nutritional *** consequences of obesity and being overweight are observed in different organs,but the kidney is one of the most *** adipose tissue causes hemodynamic alterations in the kidney that can result in renal ***,obesity is also commonly associated with other comorbidities such as chronic inflammation,hypertension and *** association of several aggravating factors is still a matter of concern in clinical and basic research because the pathophysiologic mechanisms surrounding chronic kidney disease development in obese patients remain *** review will discuss the consequences of obesity in the context of renal injury.

关键词： Overweight Obesity Kidney disease Renin-angiotensin system Diabetes

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