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Cytoprotection behind heme oxygenase-1 in renal diseases

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World Journal of Nephrology 2012年第1期1卷 4-11页

作者： Matheus Correa-Costa Mariane Tami Amano Niels Olsen Saraiva camara Laboratory of Transplantation Immunobiology Department of ImmunologyInstitute of Biomedical Sciences IVUniversity of S?o Paulo05508-000Sao PauloBrazil

Renal insults are considered a public health problem and are linked to increased rates of morbidity and mortality worldwide. The heme oxygenase(HO) system consists of evolutionary specialized machinery that degrades free heme and produces carbon monoxide, biliverdin and free iron. In this sense, the inducible isoform HO-1 seems to develop an important role and is widely studied. The reaction involved with the HO-1 molecule provides protection to injured tissue, directly by reducing the toxic heme molecule and indirectly by the release of its byproducts. The up regulation of HO-1 enzyme has largely been described as providing antioxidant, antiapoptotic, anti-inflammatory and immunomodulatory properties. Several works have explored the importance of HO-1 in renal diseases and they have provided consistent evidence that its overexpression has beneficial effects in such injuries. So, in this review we will focus on the role of HO-1 in kidney insults, exploring the protective effects of its up regulation and the enhanced deleterious effects of its inhibition or gene deletion.

关键词： Heme oxigenase-1 Renal cytoprotection Antioxidants Anti-infammatory Renal diseases

Optimal Sizing of Capacitor Bank for Increasing Substation Capacity of Mamou

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World Journal of Engineering and Technology 2023年第2期11卷 217-233页

作者： Jean Ouèrè Toupouvogui Mohamed Ansoumane camara Ansoumane Sakouvogui Mamby Keita Department of Instrumentation and Physical Measurements Higher Institute of Technology Mamou Guinea Electrical Engineering Department Polytechnic Institute Gamal Abdel Nasser University Conakry Guinea Energy Department Higher Institute of Technology Mamou Guinea Department of Physics Faculty of Sciences Gamal Abdel Nasser University Conakry Guinea

In order to increase the available power of the electrical energy distribution station and improve the voltage profile of the distribution lines, the use of shunt capacitor banks is indicated. The main results obtained during this study are: a reduction in subscribed power from 14913.978 kVA to 14010.100 kVA, a reduction in the transformer load rate from 99.4% to 93.4%, a reduction in reactive power called from 5481.729 kVAr to 481.729 kVAr, an increase in the active power transported by the substation from 8505.062 kW to 8962.323 kW, a reduction in the voltage drop from 4.8% to 3.9%, an increase in the power available at the secondary of the transformer station at full load from 13950 kW to 14700 kW and an annual electrical energy saving of 339943.48 kWh of electrical energy, therefore fuel savings and a reduction in CO2 and SO2 emissions due to this energy saving will be achieved. The installation of capacitor banks for optimization of reactive energy allowed a reduction in the current called therefore a reduction in the absorbed power: 14153.061 kVA, i.e. a reduction of 903.876 kVA. It is therefore essential that energy players are convinced of the need to install capacitors to reduce or even eliminate their reactive energy bill. This is necessarily accompanied by an investment by Electricité De Guinée by setting up active and reactive energy meters but also by implementing pricing in line with the reduction in the transfer of reactive energy in the network.

关键词： Compensation Power Reactive Optimal Battery Capacitors

Contribution of Cardiac MRI in the Diagnosis of Acute Myocarditis

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Open Journal of Radiology 2023年第1期13卷 17-25页

作者： Aboubacar Sidiki Keita Mamoudou camara Mamadou Diallo Adama Dembele Mamadou Cisse Medical Imaging Department North Franche-Comte Hospital Trevenans France Faculty of Health Sciences and Techniques Gamal Abdel Nasser University of Conakry Conakry Guinea Medical Imaging Department Elbeuf Louviers Intercommunal Hospital Center Elbeuf France Medical Imaging Department Blois Hospital Center Blois France

Objective: To describe the MRI abnormalities observed in acute myocarditis. Materials and Methods: Retrospective cross-sectional study with a descriptive aim, carried out at the North Franche-Comte Hospital, over a period of 12 months, from January 2021 to December 2021. It covered all patients who received an MRI of heart disease and were diagnosed with myocarditis. The diagnosis of myocarditis was retained in all patients on the basis of two arguments: a T2 PSIR hyper signal and a late enhancement at 15 min in T1 PSIR with gadolinium. Results: Myocarditis was diagnosed in 20 patients out of a total of 214 who performed cardiac MRI, i.e. 10.30% of cases. The average age was 33.7 ± 14.3 with extremes of 17 and 69 years. We observed a male predominance with 11 men (55%) for 9 women (45%) or a sex ratio of 1.2. Clinical suspicion of myocarditis and acute coronary syndrome were the main indications for MRI. The lesion sites were subepicardial (95%) and/or intramural (30%), respecting the subendocardium, interesting for the majority, segments 12 (anterolateral) in 50% and/or 11 (inferolateral) in 43% of cases. Global hypokinesia was observed in 30% of patients associated with a decrease in LVEF. There was no cardiac volume abnormality or valvular abnormality. Conclusion: Cardiac MRI is nowadays the most efficient non-invasive imaging in the diagnosis of acute myocarditis. The diagnosis of myocarditis was made on 2 pathognomonic signs, namely a T2 STIR hyper signal and late enhancement at 15 min in T1 PSIR after injection of gadolinium. The morphology and lesion locations were in agreement with those described in previous studies. Global hypokinesia and pericardial effusion were observed in some patients. On the other hand, there was neither valvular anomaly, nor cardiac volume anomaly.

关键词： Cardiac MRI Acute Myocarditis Acute Coronary Syndrome

Microbiological and Physico-Chemical Analysis of the Waters of the “Mamouwol” Stream in the Urban District of Mamou (Republic of Guinea)

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Journal of Water Resource and Protection 2024年第8期16卷 559-568页

作者： Mamadou Lamarana Souare Mamadou Madaniou Sow Saran camara Adama Moussa Sakho Technical Department of Laboratory Superior Institute of Technology Mamou Republic of Guinea Study and Research Center in the Environment (CERE) Gamal Abdel Nasser University of Conakry Republic of Guinea

Water is essential to life and to the sustainable socio-economic development of a nation, It is therefore interesting to have a better knowledge of the quality of this water. The aim was to determine the degree of microbiological and physico-chemical pollution of the water of the “Mamouwol” river in the town of Mamou. To do this, we chose four (4) sampling sites spread throughout the town of Mamou. During the month of March (2024), 4 water samples were analyzed to monitor the water quality of this river. The average values of the flora analyzed show that these water are heavily contaminated with bacteria indicative of fecal and metal pollution. This study showed that sites: Mam4;Mam2 and Mam1 contain the highest loads, with Total Coliform counts ranging from 1534 CFU/100 ml to 2100 CFU/100 ml, the number of faecal coliforms varies between 526 and 1240 CFU/100 ml, and that of faecal streptococci between 526 and 841 CFU/100 ml. Metal content, BOD5 and COD all comply with the laboratory’s analysis criteria, although they vary from point to point.

关键词： Pollution Water Watercourses Waterborne Diseases Microbiological Analysis

Superconductor Substrate with Critical Temperature at 212 K for Planar Antenna

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材料科学与工程（中英文版） 2010年第7期4卷 78-82页

作者： Humberto Cesar Chaves Fernandes Hugo Michel camara Azevedo Maia Department of Electrical Engineering Federal University of Rio Grande of Norte 59078-970- Natal-R~ Brazil

Contribution of Imagery in the Diagnosis of Multisystemic Sarcoidosis in the Service Radiology Department of the Mother and Child Hospital “Le Luxembourg” in Bamako: A Case Report

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Open Journal of Medical Imaging 2024年第3期14卷 79-85页

作者： Mariko Mahamane camara Mamoudou Keita Aboubacar Sidiki N’Diaye Mahamadou camara Mody Abdoulaye Fofana Youssouf Traoré Mohamed Maba Sidibé Siaka Sanogo Souleymane Keita Adama Diaman Department of Radiology Mother and Child Hospital Luxembourg Bamako Mali Medical Imaging Exploration and Diagnostic Center Conakry Guinea Assistant at the Faculty of Health Sciences and Techniques at the Gamal Abdel Nasser University of Conakry Department of Radiology Military Hospital of Bamako Bamako Mali Department of Radiology Mali Hospital Bamako Mali Department of Radiology Point G Hospital Bamako Mali

The aim of this study was to report a case of multi-visceral sarcoidosis at the Mother-Child Hospital Center (CHME) “Le Luxembourg” in Bamako, Mali. Observation: This is a patient aged 62 at the time of consultation, a housewife, residing in the Banconi district, who was referred to us for thoracic-abdominopelvic imaging for chronic liver disease. After several diagnostic errors, the thoracic-abdominopelvic CT scan and liver MRI performed in our center showed, at the thoracoabdominal level, bilateral diffuse pulmonary micronodules and bilateral mediastinal-hilar lymphadenopathy;on the abdominal level, a dysmorphic liver with plaques of steatosis and a granular appearance of the liver parenchyma without periportal fibrosis. These imaging data combined with those from the liver nodule biopsy and biology confirmed the diagnosis of sarcoidosis type II. Treatment with corticosteroids gave satisfactory results and the patient recovered after 18 months. Clinical and CT monitoring 2 years from the start of the disease and 2 months from the end of treatment showed complete resolution of the lesions. Conclusion: The multi-visceral location of sarcoidosis is an entity whose diagnosis remains difficult;diagnostic and interventional imaging has an important place in its management.

关键词： Sarcoidosis Multi Visceral Imaging CHME Luxembourg

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广东省花岗岩赤红壤的微形态特征研究

华南农业大学学报 1998年第3期19卷 82-86页

作者：戴军 M.K.camara 甘海华吴海宇华南农业大学资源环境学院几内亚共和国教育部

对广东省２个花岗岩赤红壤的微形态研究表明：骨骼颗粒以蚀变石英为主：呈斑晶状分布；土体棱块状结构发育明显，微团聚体轻微发育；细粒物质以其红色、具轻微双折射现象为主要特征；

关键词：广东省花岗岩赤红壤微形态

Immune regulatory properties of multipotent mesenchymal stromal cells:Where do we stand?

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World Journal of Stem Cells 2011年第1期3卷 1-8页

作者： ênio José Bassi Carlos Alberto Mayora Aita Niels Olsen Saraiva camara Laboratory of Transplantation Immunobiology Department of Immunology Universidade of So Paulo Centro de Ciências Biológi-cas e da Saúde Pontifícia Universidade Católica do Paraná

Multipotent mesenchymal stromal cells (MSC) can be isolated and efficiently expanded from almost every single body tissue and have the ability of self-renewal and differentiation into various mesodermal cell lineages. Moreover, these cells are considered immunologically privileged, related to a lack of surface expression of costimulatory molecules required for complete T cell activation. Recently, it has been observed that MSC are capable of suppressing the immune response by inhibiting the maturation of dendritic cells and suppressing the function of T lymphocytes, B lymphocytes and natural killer cells in autoimmune and inflammatory diseases as a new strategy for immunosuppression. The understanding of immune regulation mechanisms by MSC is necessary for their use as immunotherapy in clinical applications for several diseases.

关键词： Immunosuppression Mesenchymal stem cell Immune system Inflammation Autoimmune disease

Diagnosis and Solution of the Drinking Water Supply Network of the Municipality of Diembéring

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Computational Water, Energy, and Environmental Engineering 2024年第4期13卷 133-141页

作者： Ndiouga camara Ibrahima Diatta Lucie Andine Djitome Lamote Badiatte Séni Tamba UFR Engineering Sciences University of This This Sngal Ministry of Higher Education and Research Polytechnic School of This This Sngal

Diembéring, a municipality in Ziguinchor region (with 21 villages) has a considerable deficit in drinking water supply to the population. And yet the sources of supply are not lacking. In this part of the region, the quality water supply rate remains very low. This article follows a process of collection, analysis and exploitation of data (hydrogeological, geomorphological, geological) obtained at the site level. Then, an evaluation of the population compared to the horizon of 2041 is carried out, which allows the estimation of the evolution of the necessary drinking water needs. The geographical and hydraulic criteria allowed us to subdivide the system into two very distinct networks: two multi-village adduction systems (SAEMV1 and SAEMV2) composed of two water towers of 200 m3 each for a HMT = 45 m, serving standpipes [1]. So, for [2]: • SAEMV1 (14 villages): the population is estimated at 10,400 inhabitants in 2041 and water needs are estimated at 365.849 m3/s;• SAEMV2 (07 villages): population is estimated at 38,354 inhabitants in 2041 and drinking water needs are estimated at 1,216.537 m3/s. As designed, this article is in line with the strategy that aims to promote access to drinking water as a means of reducing poverty [3].

关键词： Component Formatting Style Styling Insert