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Effectiveness of Oral Health Education Program on Prevention of Periodontal Disease in Japanese Pregnant Women

Open Journal of Nursing 2016年第4期6卷 282-293页

作者： Mayumi Noguchi Akira Tagaya Ayako Sakoda Hitoshi Komatsuzawa Natsumi Fujiwara motoyuki sugai Japanese Red Cross Hiroshima College of Nursing Hatsukaichi Japan Japanese Red Cross Toyota College of Nursing Toyota Japan (Current) Nagano College of Nursing Komagane Japan Department of Bacteriology Hiroshima University Graduate School of Biomedical & Health Sciences Hiroshima Japan Department of Oral Microbiology Kagoshima University Graduate School of Medical and Dental Sciences Kagoshima Japan (Current) Department of Oral Health Care Promotion Tokushima University Graduate School of Biomedical Sciences Tokushima Japan (Current)

The prevalence of periodontal disease among pregnant women increases with gestational age. Therefore, oral health education in the early stage of pregnancy should prevent periodontal disease and decrease the risk of an adverse pregnancy outcome such as preterm delivery and low birth weight. However, there has been no study on oral health care intervention for prevention of periodontal disease during pregnancy. The purpose of this study was to examine the efficiency of an oral health education program on periodontal disease among Japanese low-risk pregnant women. A total of 207 pregnant women before 20 weeks of gestation were recruited. The first 131 of them were assigned to the control group and the remaining 76 to the experimental group. The experiment participants received an oral health education program including the toothpick brushing method in their early stage of pregnancy. Improvement of the self-assessment score of periodontal symptoms was used as a binary outcome variable. A logistic regression analysis indicated that the intervention (OR = 3.83) and proficiency of the toothpick brushing method (OR = 24.93) were statistically significant predictors of the outcome in the late stage of pregnancy. The positive outcome appeared after practice of the toothpick method brushing for 20 or more weeks, and was associated with the decrease in the log-transformed proportion of the count of Candida species in salivary microbiota (p = 0.026).

关键词： Periodontal Disease Pregnancy Oral Health Educational Intervention Toothpick Brushing Method

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The Effectiveness of the Continuous and Cyclic Method on CO₂-ECBM

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Natural Resources 2024年第3期15卷 69-81页

作者： Theodora Noely Tambaria Yuichi sugai Department of Earth Resources Engineering Kyushu University Fukuoka Japan

This study examines the impact of different CO2 injection methods on coalbed methane recovery. Specifically, this study investigated the effectiveness of continuously injecting CO2 versus injecting CO2 that had been soaked for two weeks. The objective was to ascertain which approach was more successful in enhancing CO2 Enhanced coalbed Methane (CO2-ECBM). The experiment involved injecting 3 MPa of CH4 into dry coal samples, allowing it to adsorb until reaching equilibrium, and then injecting 5 MPa of CO2 to recover adsorbed CH4. The continuous method recovered CH4 without detectable effluent concentration for 5 hours, but desorption efficiency was only 26% due to fast flow. On the other hand, the desorption efficiency of the cyclic method was only 12%, indicating trapped CH4. A comparison of desorption efficiency per unit of time shows the continuous method is more effective than the cyclic method. The results of this study demonstrate the continuous method is more effective for the desorption of CH4, and its efficiency can be improved by briefly soaking CO2 on coal and then reinjecting it to maximize CH4 recovery. It is advisable to limit the soaking time to prevent excessive swelling of the coal matrix, which can hinder seam flow and harm long-term gas production.

关键词： Coalbed Methane CO2 Injection Desorption Efficiency

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New role of platelets in schizophrenia:predicting drug response

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General Psychiatry 2024年第2期37卷 197-206页

作者： Yamin Zhang Yanghao Zheng Peiyan Ni sugai Liang Xiaojing Li Hua Yu Wei Wei Xueyu Qi Xueli Yu Rui Xue Liansheng Zhao Wei Deng Qiang Wang Wanjun Guo Tao Li Department of Neurobiology Zhejiang University School of Medicine Affiliated Mental Health Centre&Hangzhou Seventh People's HospitalHangzhouZhejiangChina Liangzhu Laboratory Zhejiang University MOE Frontier Science Center for Brain Science and Brain Machine IntegrationHangzhouZhejiangChina Mental Health Center and Psychiatric Laboratory West China Hospital of Sichuan UniversityChengduSichuanChina

Background Elevated platelet count(PLTc)is associated with first-episode schizophrenia and adverse outcomes in individuals with precursory ***,the impact of antipsychotic medications on PLTc and its association with symptom improvement remain *** We aimed to investigate changes in PLTc levels following antipsychotic treatment and assess whether PLTc can predict antipsychotic responses and metabolic changes after accounting for other related *** A total of 2985 patients with schizophrenia were randomised into seven *** group received one of seven antipsychotic treatments and was assessed at 2,4 and 6 *** symptoms were evaluated using the positive and negative syndrome scale(PANSS).Additionally,we measured blood cell counts and metabolic parameters,such as blood *** measures analysis of variance was used to examine the effect of antipsychotics on PLTc changes,while structural equation modelling was used to assess the predictive value of PLTc on PANSS *** PLTc significantly increased in patients treated with aripiprazole(F=6.00,p=0.003),ziprasidone(F=7.10,p<0.001)and haloperidol(F=3.59,p=0.029).It exhibited a positive association with white blood cell count and metabolic *** baseline PLTc was observed in non-responders,particularly in those defined by the PANSS-negative *** the structural equation model,PLTc,white blood cell count and a latent metabolic variable predicted the rate of change in the PANSS-negative subscale ***,higher baseline PLTc was observed in individuals with less metabolic change,although this association was no longer significant after accounting for baseline metabolic *** Platelet parameters,specifically PLTc,are influenced by antipsychotic treatment and could potentially elevate the risk of venous thromboembolism in patients with *** PLTc levels and associated factors may impede symptom improvement by

关键词： schizophrenia assessed treatment

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基于线上线下混合式教学的微生物学与免疫学课程思政探索与实践

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中国免疫学杂志 2024年第5期40卷 1114-1116,F0003页

作者：梅雪夏金婵冯龙孙颖尹素改河南中医药大学医学院郑州450046

课程思政是实现“立德树人”根本任务的重要举措。近年本课程团队基于线上线下混合式教学模式开展了微生物学与免疫学课程思政探索和实践,从课程目标、教师教学能力、线上线下教学各环节全过程全方位将课程思政有机融入其中,旨在培养“... 详细信息

课程思政是实现“立德树人”根本任务的重要举措。近年本课程团队基于线上线下混合式教学模式开展了微生物学与免疫学课程思政探索和实践,从课程目标、教师教学能力、线上线下教学各环节全过程全方位将课程思政有机融入其中,旨在培养“德才兼备”的医药人才。

关键词：混合式教学微生物学与免疫学课程思政

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Landscape gradient of autumn photosynthetic decline in Abies sachalinensis seedlings

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Journal of Forestry Research 2023年第1期34卷 187-195页

作者： Tetsuto sugai Wataru Ishizuka Toshihiro Watanabe Hokkaido Research Center Forestry and Forest Products Research InstituteHitsujigaoka 7Sapporo 062-8516Japan Plant Nutrition Laboratory Research Faculty of AgricultureHokkaido UniversitySapporo 060-8689Japan Forest Research Institute Hokkaido Research OrganizationBibaiHokkaido 079-0198Japan

Understanding what environmental factors are genetically linked to a phenologic al event is critical for predicting responses to climate *** synthetic phenology often varies among a species of evergreen conifers due to local ***,few empirical studies have revealed relevant relationships between climatic factors in provenance environments and photosynthetic *** study evaluated the effects of environmental conditions of the growing site and seed source provenance on the seasonal changes in maximal photochemical quantum yield of photo systemⅡ(Fv/Fm)in a common garden experiment with 2-year-old seedlings of Sakhalin fir(Abies sachalinensis),a representative species with local adaptation,from four seed source provenances.A logistic model was constructed to explain the seasonal variation of Fv/Fmfrom July to October and the relationships between the estimated model parameters and representative factors featuring provenance environments were *** landscape gradient of the detected model parameters responsible for the provenance environments was visualized in a map of the distribution *** lowest temperature was the most plausible factor in the growing environment to explain the seasonal changes of Fv/*** the representative meteorological factors of provenance environments,the lowest temperatures in July showed significant relationships with two model parameters,explaining the lower limit of Fv/Fmand the higher sensitivity of autumn Fv/*** estimated spatial maps of model parameters consistently showed that the higher the lowest temperature in July in the provenance environment,the lower the Fv/Fmin October and the greater the decrease in the autumn Fv/***,the lowest summer temperature could be associated with the local adaptation of autumn photosynthetic phenology in ***.

关键词： Phenology Local adaptation Genetic cline Lowest temperature

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Functional Striatal Abnormalities:A Distinct Brain Signature of Schizophrenia

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Neuroscience Bulletin 2021年第2期37卷 284-286页

作者： sugai Liang Tao Li Mental Health Center and Psychiatric Laboratory State Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China West China Brain Research Centre West China HospitalSichuan UniversityChengdu 610041China

Schizophrenia is a severe and complex mental disorder *** offers a powerful window for identifying the brain biomarkers and investigating the neuropathological mechanisms of psychiatric disorders.A study led by Professors Jiang and Liu,published recently in Nature Medicine,developed a new neuroimaging biomarker to characterize striatal dysfunction based on a multi-site functional MRI dataset with>1000 *** show that this biomarker can distinguish individuals with schizophrenia and predict the short-term effects of antipsychotic treatmem[2].

关键词： individual Signature Schizophrenia

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新工科背景下民办高校机械专业师资队伍建设的探究

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时代汽车 2024年第18期 36-38页

作者：韩素改霭宏论郑州工业应用技术学院河南郑州451100

教育兴则国兴,教育强则国强,建设教育强国是中华名族伟大复兴的基础性工程。建设具有中国特色、适应新时代发展需求的一流人才,需要建设一支学识渊博,经验丰富的强大的师资队伍,才能源源不断的培养一流人才,加快一流学科建设。对于多数... 详细信息

教育兴则国兴,教育强则国强,建设教育强国是中华名族伟大复兴的基础性工程。建设具有中国特色、适应新时代发展需求的一流人才,需要建设一支学识渊博,经验丰富的强大的师资队伍,才能源源不断的培养一流人才,加快一流学科建设。对于多数民办高校,机械类专业的师资建设还存在较多问题和挑战。文章通过分析与讨论现在阶段民办高校师资队伍建设存在的问题和不足,提出了通过校企合作的方式,组织优秀企业专业力量开展师资培训、教学研讨、思政元素挖掘、资源平台建设、校企合作指导实践等工作。旨在提高骨干教师和青年教师的工程实践能力、创新创造能力和思政育人水平,从而为新工科背景下机械设计制造及其自动化专业专业人才培养提供有力支撑。

关键词：民办高校机械专业师资培训

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New,Unexpected Pyranose-Furanose Rearrangement Towards the Synthetic Studies on Rare Sugars and Nucleosides

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复旦学报（自然科学版） 2005年第5期44卷 794-795页

作者： Takeshi sugai Deparment of Chemistry Keio University Yokohama 223-8522 Japan

Preparation of rare aminosugars such as N-acetylgalactosamine (GalNAc) in large quantities is of importance for the chemo-enzymatic synthesis of oligosaccharides. Starting from naturally abundant N-acetylglucosamine (GlcNAc), the regio- and stereoselective and new functional group transformation play important roles as the key reactions.

关键词：吡喃糖五环糖氨基糖核苷区域选择性

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小型脉冲功率发生器的电路方法与实践

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强激光与粒子束 2024年第5期36卷 1-8页

作者：江伟华德地明须贝太一余亮冯昱庄龙宇任小晶杨钧翔长冈技术科学大学极限能量密度研究中心长冈新泻9402188日本

基于实用的观点综述性地归纳了小型脉冲功率发生器的主要电路方法,从电路的储能原理和电压叠加到开关单元设计及控制信号的产生技术。以作者的实际工作内容为主,用具体的电路实例介绍了几种脉冲功率电路的基本结构和主要结果。这些电路... 详细信息

基于实用的观点综述性地归纳了小型脉冲功率发生器的主要电路方法,从电路的储能原理和电压叠加到开关单元设计及控制信号的产生技术。以作者的实际工作内容为主,用具体的电路实例介绍了几种脉冲功率电路的基本结构和主要结果。这些电路包括:电容储能Marx发生器,电感储能Marx发生器,混合储能Marx发生器,电容储能直线型变压器驱动器(LTD)和电感储能LTD。

关键词：脉冲功率高电压电力电子等离子体气体放电直线型变压器驱动器

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High current pulse forming network switched by static induction thyristor

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Matter and Radiation at Extremes 2018年第5期3卷 261-266页

作者： Juan Perez Taichi sugai Weihua Jiang Akira Tokuchi Masayuki Horie Yuya Ohshio Kazuma Ueno Nagaoka University of Technology Kamitomioka NagaokaNiigata 940-2188Japan Pulsed Power Laboratory Ltd. OgakiRittoShiga Prefecture 520-3024Japan Japan Aerospace Exploration Agency Ibaraki PrefectureTsukubaSengen 2-1-1305-8505Japan

A high-current pulse forming network (PFN) has been developed for applications to artificial solar-wind generation. It is switched by staticinduction thyristor (SIThy) and is capable of generating pulsed current of ~9.7 kA for a time duration of ~1 ms. The SIThy switch module ismade that it can be controlled by an optical signal and it can be operated at elevated electrical potential. The experiments reported in this paperused two switch modules connected in series for maximum operating voltage of 3.5 kV. The experimental results have demonstrated a pulsedhigh-current generator switched by semiconductor devices, as well as the control and operation of SIThy for pulsed power application.

关键词： Pulsed power Pulse forming network Power semiconductor device Thyristor High voltage

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