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Open Journal of Anesthesiology 2023年第12期13卷 241-253页

作者： mohamed Fouad mohamed Elmeliegy mohamed Said mostafa Elmeligy Anaesthesia Department Benha University Benha Egypt

Introduction: Study compare spinal anesthesia using hyperbaric bupivacine (0.5% - 0.75%) between fixed dose and height adjusted dose during elective cesarean section. Methods: Hundred parturients who had given their consent and were scheduled for elective cesarean section under spinal anesthesia, were divided into four groups—first group received 0.5% hyperbaric bupivacine fixed dose, the second group received 0.5% hyperbaric bupivacine in a dose adjusted to the height, the third received 0.75% hyperbaric bupivacine fixed dose, the fourth group received 0.75% hyperbaric bupivacine in a dose adjusted to height. The anesthesia onset time, haemodynamic changes, side effects and fetal outcome observed. Results: Spinal block provide excellent surgical anesthesia in all patients. Anesthesia onset time is longer in adjusted than fixed groups, in 0.5% (5 ± 0.816 vs. 3.84 ± 0.746) (P Conclusion: Adjusting dose of hyperbaric bupivacine (0.5% - 0.75%) to patient’s height, decreases the dose of bupivacine in use, it also provide adequate anesthesia for elective cesarean section with decrease the use of vasopressors, the incidence and severity of maternal hypotention also markedly reduced.

关键词： Cesarean Section Height Spinal Anesthesia Local Anesthesia

Effect of cholesterol-loaded cyclodextrin enriched extenders on the quality of pre- frozen and frozen buffalo semen

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Asian pacific Journal of Reproduction 2022年第3期11卷 146-152页

作者： Asmaa A.mostafa mohamed S.El-Belely Sayed T.Ismail Reda I.El-Sheshtawy mohamed I.Shahba Abassia Frozen Semen Center General Organization for Veterinary ServicesCairoEgypt Department of Theriogenology Faculty of Veterinary MedicineCairo UniversityGizaEgypt Department of Animal Reproduction and Artificial Insemination National Research CentreDokkiGizaEgypt

Objective:To investigate the effects of non-permeable cryoprotectant,cholesterol-loaded cyclodextrin,when added at different concentrations into cooled and frozen-thawed semen extended with Tris-citrate-fructose egg yolk glycerol and lecithin-based ***:A total of 40 ejaculates from four buffalo bulls were collected using artificial *** were extended with one of Tris-citrate-fructose egg yolk glycerol and lecithin-based extenders which contained different concentrations[0(control),0.75,1.50,2.25 and 3.00 mg/mL]of cholesterol-loaded *** extended semen samples were cooled to 5曟and then frozen slowly to-196曟in 0.25 mL ministraws before being stored in liquid nitrogen pending its *** motility,live sperm,normal sperm morphology,sperm membrane integrity and acrosome morphology were ***:Supplementation of cholesterol-loaded cyclodextrin improved progressive motility,viability,morphology and acrosome as well as plasma membrane integrities at 1.50-2.25 mg/mL depending upon types of used extenders and stages of pre-and post-freezing process(P<0.01).The best concentration was 1.50 mg/mL at pre-freeze stage and 2.25 mg/mL at ***,greater concentration(3.00 mg/mL)of cholesterol-loaded cyclodextrin had a detrimental effect compared to the control group with the two evaluated extenders(P<0.01).Conclusions:Cholesterol-loaded cyclodextrin supplementation at 1.50-2.25 mg/mL concentration could improve pre-frozen and post-thawed buffalo sperm *** most suitable concentration is 1.50 mg/mL at pre-freeze stage and 2.25 mg/mL at post-freezing.

关键词： Buffalo Semen Tris Cooling Cryopreservation Cholesterol-loaded cyclodextrin Semen evaluation

Quantifying non-classical correlations under thermal effects in a double cavity optomechanical system

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Chinese Physics B 2020年第2期29卷 121-128页

作者： mohamed Amazioug Larbi Jebli mostafa Nassik Nabil Habiballah Department of Physics Ecole Normale Supérieure(ENS)Mohammed V University in RabatMorocco LPHE-MS Department of PhysicsFaculty of SciencesMohammed V UniversityRabatMorocco EPTHE Department of PhysicsFaculty of SciencesIbn Zohr UniversityAgadirMorocco Faculty of Applied Sciences Ibn Zohr UniversityAit-MelloulMorocco Abdus Salam International Center for Theoretical Physics Strada Costiera1134151TriesteItaly

We investigate the generation of quantum correlations between mechanical modes and optical modes in an optomechanical system,using the rotating wave *** system is composed of two Fabry-Pérot cavities separated in space;each of the two cavities has a movable *** aim is the evaluation of entanglement between mechanical modes and optical modes,generated by correlations transfer from the squeezed light to the system,using Gaussian intrinsic entanglement as a witness of entanglement in continuous variables Gaussian states,and the quantification of the degree of mixedness of the Gaussian states using the ***,we quantify nonclassical correlations between mechanical modes and optical modes even beyond entanglement by considering Gaussian geometric discord via the Hellinger ***,entanglement,mixdness,and quantum discord are analyzed as a function of the parameters characterizing the system(thermal bath temperature,squeezing parameter,and optomechanical cooperativity).We find that,under thermal effect,when entanglement vanishes,purity and quantum discord remain ***,the Gaussian Hellinger discord is more robust than *** effects of the other parameters are discussed in detail.

关键词： cavity optomechanics quantum correlations Gaussian intrinsic entanglement purity Gaussian Hellinger discord Gaussian geometric discord

Monitoring and analysing the Emirate of Dubai’s land use/land cover changes:an integrated,low-cost remote sensing approach

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International Journal of Digital Earth 2018年第11期11卷 1132-1150页

作者： Samy Ismail Elmahdy mohamed mostafa mohameda Civil and Environmental Engineering Department College of Engineering United Arab Emirates UniversityAl-AinUnited Arab Emirates Irrigation and Hydraulics Department Faculty of EngineeringCairo UniversityGizaEgypt

This study presents a modified low-cost approach,which integrates the spectral angle mapper and image difference algorithms in order to enhance classification maps for the purpose of monitoring and analysing land use/land cover change between 2000 and 2015 for the Emirate of *** approach was modified by collecting 320 training samples from QuickBird images with a spatial resolution of 0.6 m,as well as carrying out field observations,followed by the application of a 3×3 Soble filter,sieving classes,majority/minority analysis,and clump classes of the obtained classification *** accuracy assessment showed that the targeted 2000,2005,2010 and 2015 classification maps have 88.1252%,89.0699%,90.1225%and 96.0965%accuracy,*** results showed that the built-up area increased by 233.721 km^(2)(5.81%)between 2000 and 2005 and continues to increase even up and till the present *** assessment of changes in the periods 2000–2005 and 2010–2015 confirmed that net vegetation area losses were more pronounced from 2000 to 2005 than from 2010 to 2015,dropping from 47,618 to 40,820 km^(2),*** study is aimed to assist urban planners and decision-makers,as well as research institutes.

关键词： Dubai change detection image difference SAM algorithm

Determinants of Schistosoma mansoni transmission in hotspots at the late stage of elimination in Egypt

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Infectious Diseases of Poverty 2022年第5期11卷 95-96页

作者： Ramy mohamed Ghazy Walid Ismail Ellakany Mai M.Badr Nehad E.M.Taktak Heba Elhadad Sarah MAbdo Ayat Hagag Abdel Rahman Hussein mohamed mostafa Tahoun 不详 Department of Tropical Medicine Faculty of MedicineAlexandria UniversityAlexandriaEgypt

Background In certain settings,the prevalence and severity of schistosoma infection do not lessen despite repeated rounds of preventative chemotherapy;these areas are known as *** study aimed to investigate the role of human practices,besides environmental and malacological factors,in the maintenance of the Schistosoma mansoni infection transmission chain in hotspot areas in *** This cross-sectional study was conducted between July and November 2019 in Kafr El-Sheikh Governorate,Egypt.A pre-designed structured interviewing questionnaire was used to collect humanitarian *** samples were collected from children aged 6–15 years on three successive days and examined using the Kato-Katz ***,water and snail samples were taken from watercourses surrounding *** were identified based on their shell morphology and structure and tested for cercaria *** samples were analyzed for their physicochemical and biological *** A total of 2259 fecal samples(1113 in summer and 1146 in fall)were collected from 861 *** 46.9%of the participants were males,and 31.8%were aged 6–10 *** prevalence of *** infection was higher during the summer than during the fall(19.1%vs 7.2%,respectively,P<0.01).The intensity of infection(light,moderate,and heavy)during summer versus fall was(93.55 vs 89.38%,6.45 vs 8.85%,and 0.00%vs 1.77%),respectively(P<0.05).A higher prevalence of human infection was observed among males than females[OR=1.63,95%confidence interval(CI):1.10–2.40,P=0.015],children aged 11–15 years than among their counterparts aged 6–10 years(OR=2.96,95%CI:1.72–5.06,P<0.001),and mothers with a low level of education(OR=3.33,95%CI:1.70–6.52,P<0.001).The main identified risk factors were contacting the main body of water-canal for washing clothes(OR=1.81,95%CI:1.12–2.49,P=0.015),land irrigation(OR=2.56,95%CI:1.32–4.96,P=0.004),water collection(OR=2.94,95%CI:1.82–4.73,P<0.001),bathing(

关键词： Schistosoma mansoni Praziquantel Biomphalaria alexandrina Community engagement Transmission cycle Neglected tropical diseases

Mid-term results of sub-trochanteric valgus osteotomy for symptomatic late stages Legg-Calvé-Perthes disease

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World Journal of Orthopedics 2023年第5期14卷 328-339页

作者： Khaled M Emara Ramy Ahmed Diab Ahmed K Emara mohamed Eissa mostafa Gemeah Shady Abdelghaffar Mahmoud Department of Orthopedic Surgery Ain Shams UniversityCairo 11591Egypt Department of Orthopedic Surgery Cleveland Clinic FoundationClevelandOH 9500United States Health Care Innovation Program Arizona State UniversityTempeAZ 85287United States

BACKGROUND The treatment of late stages of Legg-Calvé-Perthes disease(LCPD)is *** the concept of femoral head containment is a well-established technique of treatment,its use remains debatable in the late stages of the disease,as it does not improve symptoms in terms of limb length discrepancy and *** To assess the results of subtrochanteric valgus osteotomy in symptomatic patients with late-stage Perthes *** From 2000 to 2007,36 symptomatic patients with late stage of Perthes disease were surgically treated with subtrochanteric valgus osteotomy and followed-up for 8 to 11 years using the IOWA score and range of motion(ROM)*** Mose classification was also assessed at the last follow-up to reflect possible *** patients were 8 years old or older at the time of surgery,in the post-fragmentation stage,and complaining of pain,limited ROM,Trendelenburg gait,and/or abductor *** The preoperative IOWA score(average:53.3)markedly improved at the 1-year post follow-up period(average:85.41)and then slightly improved at the last follow-up(average:89.4)(P value<0.05).ROM improved,with internal rotation increased on average by 22°(from 10°preoperatively to 32°postoperatively)and abduction increased on average by 15.9°(from 25°preoperatively to 41°postoperatively).The mean Mose deviation of femoral heads was 4.1 mm at the end of the follow-up *** tests used were the paired t-test and Pearson correlation test,where the level of significance was a P value less than *** Subtrochanteric valgus osteotomy can be a good option for symptomatic relief in patients with late-stage of LCPD.

关键词： Legg-Calvé-Perthes disease Femoral head avascular necrosis Valgus osteotomy Deformity correction Post fragmentation stage Late stage Perthes

Toxoplasma gondii infection can induce retinal DNA damage: an experimental study

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International Journal of Ophthalmology(English edition) 2014年第3期7卷 431-436页

作者： Nagwa mostafa El-Sayed Eman mohamed Aly Department of Medical Parasitology Research Institute of Ophthalmology Department of Basic Science Biophysics and Laser Science Unit Research Institute of Ophthalmology

AIM:To detect whether Toxoplasma gondii(***)infection of mice can induce retinal DNA ***:A total of 20 laboratory-bred male Swiss albino mice were used and divided into four groups:control group(non-infected animals);*** infected group;immunosuppressed infected group;and infected group treated with sulfadiazine and *** eyes were collected 6wk post infection and retinas were *** retina was immediately processed for comet assay and the frequency of tailed nuclei(DNA damage)was *** addition,retinal DNA damage was revealed by various comet assay parameters that were provided by the image analysis software including tail length,percentage of DNA in the tail,percentage of tailed cells and tail ***:The obtained results showed that *** infection induced a statistically significant increase in the frequency of tailed nuclei,tail length,percentage of DNA in the tail,and tail moment in mice retinal cells compared to the control group(which showed some degree of DNA damage).In immunosuppressed infected group,retinal DNA damage was severing and there was significant increase in various comet assay parameters compared to both control and infected *** treatment with sulfadiazine and pyrimethamine,retinal DNA damage decreased and all comet assay parameters showed a statistical significant decrease compared to infected ***:*** infection can induce DNA damage in mice retinal cells.

关键词： Toxoplasma gondii retinochoroiditis DNA damage comet assay

An E-Business Event Stream Mechanism for Improving User Tracing Processes

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Computers, Materials & Continua 2021年第10期69卷 767-784页

作者： Ayman mohamed mostafa Saleh N.Almuayqil Wael Said College of Computers and Information Sciences Jouf UniversitySakaka72314Saudi Arabia Faculty of Computers and Informatics Zagazig UniversityZagazig44519Egypt College of Computer Science and Engineering Taibah UniversityMedina42353Saudi Arabia

With the rapid development in business transactions,especially in recent years,it has become necessary to develop different mechanisms to trace business user records in web server log in an efficient *** business transactions have increased,especially when the user or customer cannot obtain the required *** example,with the spread of the epidemic Coronavirus(COVID-19)throughout the world,there is a dire need to rely more on online business *** order to improve the efficiency and performance of E-business structure,a web server log must be well utilized to have the ability to trace and record infinite user *** paper proposes an event stream mechanism based on formula patterns to enhance business processes and record all user activities in a structured log *** user activity is recorded with a set of tracing parameters that can predict the behavior of the user in business *** experimental results are conducted by applying clustering-based classification algorithms on two different datasets;namely,Online Shoppers Purchasing Intention and Instacart Market Basket *** clustering process is used to group related objects into the same cluster,then the classification process measures the predicted classes of clustered *** experimental results record provable accuracy in predicting user preferences on both datasets.

关键词： Business transactions event stream log file tracing parameters clustering-based classification

Enhancing mechanical behaviors of collapsible soil using two biopolymers

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Journal of Rock Mechanics and Geotechnical Engineering 2017年第2期9卷 329-339页

作者： mohamed Ayeldeen Abdelazim Negm mostafa El-Sawwaf Masaki Kitazume Structural Engineering Department Tanta UniversityTantaEgypt Faculty of Engineering Zagazig UniversityZagazigEgypt Civil and Environmental Engineering Department Tokyo Institute of TechnologyTokyoJapan

This study aims to investigate the possibility of using biopolymer(environmental friendly material) to enhance the mechanical behaviors of collapsible *** types of biopolymers were(xanthan gum and guar gum) used in this study due to their stable behaviors under severe conditions and their availability with reasonable *** experimental program focused on three major soil properties,*** characterizations,collapsible potential and shear *** three properties are essential in process of soil *** biopolymer concentrations were used in this study and the experimental program was performed at two curing periods(soon after mixing the soil with the biopolymer and after one week curing time).Shear parameters were measured for the treated specimens under both soaked and unsoaked conditions,while a collapsible potential test was performed under different mixing conditions(wet mix and dry mix).A numerical model was built to predict the behavior of the treated collapsible soil after and before water *** results indicated that the ability of both xanthan gum and guar gum can be used as improvement materials for collapsible soil *** collapsible potential has been reduced from 9%to 1%after mixing the soil with 2%biopolymer concentration in the wet *** one week curing,the cohesion has been increased from 8.5 kPa to105 kPa by increasing the xanthan gum concentration from zero to 2%,leading to an overall improvement in soil shear *** also proves that the guar gum is superior to the xanthan *** shear strength of soil can be increased by about 30%when using the guar gum in comparison with the xanthan gum at the same conditions;however,the collapsible potential of soil material will be reduced by about 20%.

关键词： Collapsing soil Xanthan gum Guar gum Collapsible potential Shear strength Compaction characterizations Numerical model

Induction of sub-G0 arrest and apoptosis by seed extract of Moringa peregrina（Forssk.） Fiori in cervical and prostate cancer cell lines

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Journal of Integrative Medicine 2019年第6期17卷 410-422页

作者： Maged mohamed Maher Abou-Hashem Dina mohamed Abo-elmatty Noha mostafa Mesbah Ahmed mohamed Abd EL-Mawgoud Faculty of Pharmacy Pharmacognosy DepartmentZagazig UniversityZagazig 44511Egypt Faculty of Pharmacy Biochemistry DepartmentSuez Canal UniversityIsmailia 41522Egypt Egyptian International Pharmaceuticals Industries Company Tenth of Ramadan City 44629Egypt

Objective: This study investigated cytotoxicity and induction of apoptosis in human cervical cancer cells(HELA) and prostate cancer cells(PC-3) using the most active fraction of Moringa peregrina seed ***: Dried and powdered seeds were extracted using 95% ethanol. The total ethanolic extract was further dissolved in distilled water and separated into petroleum ether, chloroform, ethyl acetate and aqueous extracts. Based on the results of in vitro anticancer studies of all extracts, the most highly active extract was selected for evaluation of apoptosis induction and cell cycle analysis on HELA and PC-3 cells at its half maximal inhibitory concentration using flow cytometry;DNA fragmentation by agarose gel electrophoresis and the expression of protein were measured by Western ***: The chloroform fraction from the ethanolic extract of M. peregrina(CFEE) was the most active antitumor fraction. The selectivity index, determined using the normal Vero cell line, indicated that CFEE had a high degree of selectivity against HELA and PC-3 cells. CFEE induced apoptosis, confirmed by cell cycle arrest at sub-G0 phase and DNA fragmentation. CFEE induced an increase in mRNA expression of caspase-3, a decrease in Bcl-2 mRNA expression, and decreased ATP levels. CFEE increased protein expression of caspase-3 and decreased protein expression of poly-ADP-ribose polymerase-1(PARP-1).Flow cytometric analysis showed an appreciable increase in the number of cells in the early apoptotic stage in CFEE-treated HELA and PC-3 cells. CFEE treatment significantly increased lipid peroxidation(malondialdehyde level) in HELA and PC-3 ***: Seed extract of M. peregrina displayed a significant antitumor effect through apoptosis induction in HELA and PC-3 cells.

关键词： Moringa peregrina Fractionation Antiproliferation Apoptosis