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Nano Research 2024年第3期17卷 2145-2153页

作者： Tandra Ghoshal Michael A.morris School of Chemistry AMBER and CRANNTrinity College DublinDublinIrelandD02 AK60

Herein,we demonstrate the fabrication of sub-20 nm MoS_(2) horizontal nanowire arrays on silicon substrates using a self-assembled block copolymer assisted in situ inclusion *** separated long-range ordered polystyrene-b-polyethylene oxide(pS-b-pEO)block copolymer(BCp)line-space nanopatterns were achieved through thermo-solvent *** patterns produced had long-range order and domain sizes>1μ*** BCp structures were lightly etched and modified by anhydrous ethanol to facilitate insertion of molybdenum precursor within the film maintaining the parent BCp *** ordered molybdenum oxide nanowire arrays were then fabricated by ultraviolet(UV)/ozone treatment at room *** oxides were converted to sulphides by thermal evaporation at different temperatures in Ar/H_(2) environment.X-ray photoelectron spectroscopy revealed the composition and phases of the molybdenum oxide and sulphide *** mapping was performed to investigate the interfaces between the oxide and sulphide nanowires with the substrate *** formation and stability of the sulphide nanowires were studied at different *** photoluminescence and Raman properties were studied at different formation temperatures to investigate defects and estimate the number of layers.

关键词： MoS_(2) block copolymer nanowires inclusion X-ray photoelectron spectroscopy(XpS) mapping photoluminescence

William morris,Establishing the Foundation for the Advancement of TCM in the US

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Chinese Medicine and Culture 2024年第1期7卷 29-40页

作者： Ioannis Solos Charles Buck William morris Saint George Clinic and Research Institute Scottsdale 85251the United States of America Northern College of Acupuncture Micklegate YO16LJthe United Kingdom AOMA Graduate School of Integrative Medicine Austin 78745the United States of America

The interview was conducted on March 2nd, 2023 by Ioannis Solos and Charles Buck. William morris has sustained practice since 1980. He has served on the California, Texas and Massachusetts professional Associations, as well as the National Association. He has tendered 20 years of service to the field through academic medicine, earning a master’s degree in medical education to assist in developing Chinese medical doctoral programs and institutional review boards. He earned an OM.d. in 1988, a dAOM in 2002, and a ph.d. focused on pulse diagnosis as clinical epistemology in 2009. He has published five books, including TCM Case Studies dermatology, Li Shi-zhen pulse Studies: An Illustrated Guide, Neoclassical pulse diagnosis, Cycles in Medical Astrology, and Transformation: Treating Trauma with Acupuncture and Herbs.

关键词： Acupuncture sustained diagnosis

Recent innovations in laser additive manufacturing of titanium alloys

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International Journal of Extreme Manufacturing 2024年第3期6卷 2-37页

作者： Jinlong Su Fulin Jiang Jie Teng Lequn Chen Ming Yan Guillermo Requena Lai-Chang Zhang Y morris Wang Ilya V Okulov Hongmei Zhu Chaolin Tan College of Materials Science and Engineering Hunan UniversityChangsha 410082People’s Republic of China Singapore Institute of Manufacturing Technology(SIM Tech) Agency for ScienceTechnology and Research(A∗STAR)5 Cleantech LoopSingapore 636732Singapore department of Materials Science and Engineering Southern University of Science and TechnologyShenzhen 518055People’s Republic of China Institute of Materials Research German Aerospace Center(DLR)Linder Höhe51147 CologneGermany Centre for Advanced Materials and Manufacturing Edith Cowan University270 Joondalup DriveJoondalupPerthWestern Australia 6027Australia department of Materials Science and Engineering University of CaliforniaLos AngelesCA 900095United States of America Leibniz Institute for Materials Engineering-IWT Badgasteiner Str.328359 BremenGermany Faculty of production Engineering University of BremenBadgasteiner Str.128359 BremenGermany Key Laboratory of Hunan province of Equipment Safety Service Technology under Extreme Environment University of South ChinaHengyangPeople’s Republic of China RWTH Aachen University Metallic Structures and Materials Systems for Aerospace EngineeringD-52062 AachenGermany

Titanium(Ti)alloys are widely used in high-tech fields like aerospace and biomedical *** additive manufacturing(LAM),as an innovative technology,is the key driver for the development of Ti *** the significant advancements in LAM of Ti alloys,there remain challenges that need further research and development *** recap the potential of LAM high-performance Ti alloy,this article systematically reviews LAM Ti alloys with up-to-date information on process,materials,and *** feasible solutions to advance LAM Ti alloys are reviewed,including intelligent process parameters optimization,LAM process innovation with auxiliary fields and novel Ti alloys customization for *** auxiliary energy fields(***,acoustic,mechanical deformation and magnetic fields)can affect the melt pool dynamics and solidification behaviour during LAM of Ti alloys,altering microstructures and mechanical *** kinds of novel Ti alloys customized for LAM,like peritecticα-Ti,eutectoid(α+β)-Ti,hybrid(α+β)-Ti,isomorphousβ-Ti and eutecticβ-Ti alloys are reviewed in ***,machine learning in accelerating the LAM process optimization and new materials development is also *** review summarizes the material properties and performance envelops and benchmarks the research achievements in LAM of Ti *** addition,the perspectives and further trends in LAM of Ti alloys are also highlighted.

关键词： additive manufacturing titanium alloys auxiliary field machine learning aerospace materials lightweight materials novel alloys

睾酮替代治疗性功能减退合并心绞痛患者可以改善缺血和提高生活质量

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世界核心医学期刊文摘（心脏病学分册） 2005年第1期1卷 20-20页

作者： Malkin C.J. pugh p.J. morris p.d. K.S. Channer 张明娟 M131 Cardiology Royal Hallamshire Hospital Glossop Road Sheffield S102JF United KingdomDr.

Background: Low serum testosterone is associated with several cardiovas cular r isk factors including dyslip.d.emia, adverse clotting profiles, obesity, and ins ulin resistance. Testosterone has been reported to improve symptoms of angina an d delay time to ischaemic threshold in unselected men with coronary disease. Obj ective: This randomised single blind placebo controlled crossover study compar ed testosterone replacement therapy (Sustanon 100) with placebo in 10 men with isc haemic heart disease and hypogonadism. Results: Baseline total testosterone and bioavailable testosterone were respectively 4.2 (0.5) nmol/l and 1.7 (0.4) nmol/ l. After a month of testosterone, delta value analysis between testosterone and placebo phase showed that mean (Sd) trough testosterone concentrations increased significantly by 4.8 (6.6) nmol/l (total testosterone) (p=0.05) and 3.8 (4.5) n mol/l (bioavailable testosterone) (p=0.025), time to 1 mm ST segment depression assessed by Bruce protocol exercise treadmill testing increased by 74 (54) secon ds (p=0.002), and mood scores assessed with validated questionnaires all improve d. Compared with placebo, testosterone therapy was also associated with a signif icant reduction of total cholesterol and serum tumour necrosis factor αwith del ta values of -0.41 (0.54) mmol/l (p=0.04) and -1.8 (2.4) pg/ml (p=0.05) respec tively. Conclusion: Testosterone replacement therapy in hypogonadal men delays t ime to ischaemia, improves mood, and is associated with potentially beneficial r eductions of total cholesterol and serum tumour necrosis factor α.

关键词：睾酮替代治疗性功能减退生活质量男性冠心病平板运动试验血浆睾酮血浆总胆固醇 Bruce 异常脂蛋白血症缺血性心脏病

Testosterone and cardiovascular disease in men

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Asian Journal of Andrology 2012年第3期14卷 428-435,I0007页

作者： paul d morris Kevin S Channer Sheffield Teaching Hospital NHS Trust Sheffield S10 2JF UK

despite regional variations in the prevalence of coronary artery disease （CAd）, men are consistently more at risk of developing and dying from CAd than women, and the gender-specific effects of sex hormones are implicated in this inequality. This ＇perspectives＇ article reviews the current evidence regarding the cardiovascular effects of testosterone in men including an examination of the age-related decline in testosterone, the relationship between testosterone levels and coronary disease, coronary risk factors and mortality. We also review the vaso-active effects of testosterone, and discuss how these have been used in men with heart failure and angina. We discuss the ＇cause＇ versus ＇effect＇ controversy, regarding low testosterone levels in men with coronary heart disease, as well as concerns over the use of testosterone replacement therapy in middle aged and elderly men. The article concludes with a discussion regarding the future direction for work in this interesting area, including the relative merits of screening for, and treating hypogonadism with testosterone replacement therapy in men with heart disease.

关键词： atherosclerosis chronic heart failure ischaemic heart disease replacement therapy testosterone

Raman spectroscopy monitors adverse bone sequelae of cancer radiotherapy

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Chinese Chemical Letters 2015年第4期26卷 401-406页

作者： Bo Gong Michael d.morris department of Chemistry College of LiteratureScience and the ArtsUniversity of Michigan

Raman spectroscopy provides information on bone chemical composition and structure via widely used metrics including mineral to matrix ratio, mineral crystallinity and carbonate content, collagen cross- linking ratio and depolarization ratios. These metrics are correlated with bone material properties, such as hardness, plasticity and Young＇s modulus. We review application of Raman spectroscopy to two important irradiated animal models： the mouse tibia, a model for damage to cortical bone sites including the rib （breast cancer） and to healthy tissue adjacent to extremity sarcomas, and the rat mandible, a model for radiation damage in head and neck cancer radiotherapy. Longitudinal studies of irradiated mouse tibia demonstrate that radiation-induced matrix abnormalities can persist even 26 weeks post- radiation. polarized Raman spectroscopy shows formation of more ordered orientation of both mineral and collagen. At 8 weeks post-radiation, irradiated rat hemimandible exhibits transient hyperminer- alization, increased collagen cross-linking and decreased depolarization ratios of mineral and collagen. A standard radioprotectant, amifostine, mitigates rat mandible radiation damage, with none remaining detectable 18 weeks post-radiation. Already a powerful tool to monitor radiation damage, Raman spectroscopy may be important in development of new radiotherapy protocols and radioprotective agents. Further in vfvo studies of radiation effects on the rodent models are underway, as are development of methodologies for eventual use in human subjects.

关键词： BoneRaman spectroscopyCancer radiotherapy

Results of selective decontamination with oral neomycin and metronidazole for major colorectal surgery in Australia:A cohort study

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Laparoscopic, Endoscopic and Robotic Surgery 2024年第2期7卷 72-78页

作者： James Wei Tatt Toh devansh Shah Henry Wang Charlotte Kwik Joseph do Woong Choi Chelsie Leonie Beinke paul morris Eleni Baird-Gunning Geoffrey peter Collins Fiona Gavegan Karen Shedden Toufic El-Khoury Nimalan pathma-Nathan Kerry Hitos department of Colorectal Surgery Westmead HospitalWestmeadNew South WalesAustralia The University of Sydney Westmead HospitalWestmeadNew South WalesAustralia Western Sydney University New South WalesAustralia University of Notre dame New South WalesAustralia Westmead Research Centre for Evaluation of Surgical Outcomes Westmead HospitalSydneyAustralia

Objective The role of selective decontamination with oral antibiotics(OABs)and mechanical bowel preparation(MBp)prior to elective colorectal surgery is still widely *** objective of this study was to compare the outcomes of selective decontamination with neomycin,metronidazole and MBp compared to those of decontamination with MBp alone or with no *** Selective decontamination with neomycin and metronidazole combined with bowel preparation was introduced prior to elective colorectal surgery as part of an enhanced recovery after surgery program at Westmead Hospital,a major Australian tertiary referral hospital,between June 2017 and January *** between short-term outcomes of OAB+MBp and MBp/no preparation were made using prospectively collected data on length of stay(LOS),readmission,mortality within 30 days,anastomotic leakage(AL),surgical site infection(SSI),urinary tract infection,deep venous thrombosis and/or pulmonary embolism,pneumonia,and ***-up was limited to hospital stays and subsequent presentations within the health district within thirty days of *** Mann-Whitney U test was used to analyse continuous data,and the chi-square test was used for categorical *** and multivariate regression modelling was performed to identify risk factors associated with an increased likelihood of SSI and *** patients with oral neomycin and metronidazole combined with bowel preparation had reduced superficial SSI(2.7%vs.7.6%,p=0.043)and overall complications(32.7%vs.44.6%,p=0.020),particularly Clavien-dindo 1 complications(7.3%vs.16.5%,p=0.009).However,the differences in AL(2.7%vs.4.5%,p=0.369)and organ/space SSI(1.3%vs.3.7%,p=0.327)were not statistically *** median LOS(6 d vs.6 d,p=0.370)was not different between the *** Selective decontamination with neomycin and metronidazole reduces the risk of SSIs and overall *** was a trend to toward a lower AL,but this differ

关键词： Neomycin Metronidazole Colorectal surgery Anastomotic leakage Surgical site infection

development of a facile block copolymer method for creating hard mask patterns integrated into semiconductor manufacturing

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Nano Research 2016年第10期9卷 3116-3128页

作者： Tandra Ghoshal Matthew T. Shaw Justin d. Holmes Michael A. morris department of Chemistry and Tyndall National Institute University College Cork Cork Ireland AMBER Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN) Trinity College Dublin Dublin Ireland Intel Ireland Ltd. Collinstown Industrial Estate Co. Kildare Ireland School of Chemistry Trinity College Dublin Dublin Ireland

Our goal is to develop a facile process to create patterns of inorganic oxides and metals on a substrate that can act as hard masks. These materials should have high etch contrast （compared to silicon） and so allow high-aspect-ratio, high- fidelity pattern transfer whilst being readily integrable in modem semiconductor fabrication （FAB friendly）. Here, we show that ultra-small-dimension hard masks can be used to develop large areas of densely packed vertically and horizontally orientated Si nanowire arrays. The inorganic and metal hard masks （Ni, NiO, and ZnO） of different morphologies and dimensions were formed using microphase- separated polystyrene-b-poly（ethylene oxide）（pS-b-pEO） block copolymer （BCp） thin films by varying the BCp molecular weight, annealing temperature, and annealing solvent（s）. The self-assembled polymer patterns were solvent-processed, and metal ions were included into chosen domains via a selective inclusion method. Inorganic oxide nanopatterns were subsequently develop.d.using standard techniques. High-resolution transmission electron microscopy studies show that high-aspect-ratio pattern transfer could be affected by standard plasma etch techniques. The masking ability of the different materials was compared in order to create the highest quality uniform and smooth sidewall profiles of the Si nanowire arrays. Notably good performance of the metal mask was seen, and this could impact the use of these materials at small dimensions where conventional methods are severely limited.

关键词： block copolymer self-assembly hard mask silicon nanowires

dominant species of mid-elevation grasslands of the uKhahlamba-drakensberg park are predicted to be largely immune to climate change

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山地科学学报(英文) 2023年第9期20卷 2468-2486页

作者： debbie JEWITT Craig d.morris Tim G.O’CONNOR Michelle J.TEddER Ezemvelo KZN Wildlife Scientific ServicesPO Box 13053Cascades 3202South Africa School of Animal Plant and Environmental SciencesUniversity of the WitwatersrandJohannesburgPrivate Bag X3WITS 2050South Africa Agricultural Research Council-Animal production(ARC-Ap) ℅School of Life Sciences University of KwaZulu-NatalPrivate Bag X01Scottsville 3209PietermaritzburgSouth Africa School of Life Sciences University of KwaZulu-NatalPrivate Bag X01Scottsville 3209PietermaritzburgSouth Africa

Anticipating global change impact on natural vegetation,especially in poorly researched systems,requires an understanding of the environmental factors that most strongly influence the organisation of plant communities at different *** environmental relations of plant communities in the drakensberg mountains of South Africa remain poorly *** study investigated the influence of selected environmental determinants on the dominant species of plant community organisation in this *** order to provide an overview of the influence of the environment on botanical composition and plant diversity,this study,conducted as four discrete exercises,investigated the interplay of altitude,aspect and slope on the abundance of selected species,and to examine the influence of latitude,geological substrate and local topography on species *** diversity showed no pattern of response to investigated environmental *** composition was related to temperature and solarradiation *** altitude sites facing east were distinct for non-graminoid *** and latitude exerted a pronounced effect on species composition,confounded by longitude and precipitation *** substrate,in concert with slope steepness and orientation,influenced composition,restricting the abundance but not distribution of some *** individualistic responses were found for C_3,C_4,and non-graminoid species in relation to altitude,slope and *** and aspect mediate the effects of altitude and hence temperature for some *** study has demonstrated the complexity of drivers influencing species and compositional distribution in the drakensberg and permits a preliminary consideration of potential changes in the composition and dominance structure of mid-elevation grasslands in response to climate *** dominant grass species were widespread across environmental gradients,occupying currently warm,cool,moist and dry habitats

关键词： drakensberg Environmental gradients Grasslands Mountain biodiversity Vegetation

Mechanical Behaviour and Structure Instability of Al_3Ti Alloy

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Journal of Materials Science & Technology 1994年第1期10卷 1-14页

作者： d.G.morris(Institute of Structural Metallurgy, University of Neuchatel, Avenue de Bellevaux 51, Neuchatel, Switzerland) Univ of Neuchatel Neuchatel Switzerland

Trialuminide alloys of elements such as Ti. Nb or Zr are of particular interest as materials for high temperature usage because their density is very low and specific strength and elastic rnoduli are then very high. This report concentrates on recent work on Al3Ti alloys which have been alloyed with ternary elements such that the higher symmetry ordered cubic structure is obtained, leading to somewhat easier operation of deformation mechan isms and hence improved ductility and *** details of the crystal structure of cubic trialuminides are considered here and it is shown that the materials generally possess some remnant tetragonal chemical ordering which can affect their me chanical behaviour. In addition the compositional range over which a stable single phase is retained is shown to be extremely small, such that in most cases the materials examined show some form of microstructural instability. These instabilities affect the mechanical behaviour of the materials, for exarnple producing general strengthening. leading to precipitation hardening du ring hig h temperature testing, and causing age hardening instabilities during high temperature static or dynamic *** structural instabifity feads to significant modifications at superdislocations, affecting both the dislocation cores and their associated ApB's. Failure for these cubic materials still occurs at very small plastic strains and seems to be determined by difficulties of superdislocation creation near a propagating crack rather than by problems of suitable dislocation configuration and mobility. possible ways to enhance ductility and toughness by alloying and microstructural modification will be discussed.

关键词： Ti Figure Mechanical Behaviour and Structure Instability of Al3Ti Alloy Al