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双气囊小肠镜与推进式肠镜检查的对比

世界核心医学期刊文摘（胃肠病学分册） 2006年第1期2卷 32-33页

作者： Mat.umot. t. moriyama t. Esaki M. 张诗峰 Depart.ent.of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Maidashi 3-1-1 Higashi-ku Fukuoka 812-8582 Japan Dr.

Background: Double-balloon ent.roscopy (DBE) is a novel procedure for t.e diagnosis of small-bowel pat.ology. t.e aim of t.is ret.ospect.ve st.dy was t. compare t.e performance and t.e diagnost.c value of ant.grade DBE wit. t.ose of push ent.roscopy (PE). Met.ods: We reviewed endoscopic and hist.logic findings in 118 pat.ent. examined by PE or ant.grade DBE during a period 1980 t. 2004. t.e maximal lengt. of insert.on under plain radiograph was compared bet.een pat.ent. examined by PE and t.ose examined by ant.grade DBE. Diagnost.c yield was compared among pat.ent. st.at.fied by indicat.on for ent.roscopy and t.e duodenal pat.ology. Result.: Ninet.-one pat.ent. were examined by PE and 27 pat.ent. by ant.grade DBE. Lengt. of insert.on from t.e ligament.of t.eit. was significant.y great.r in ant.grade DBE (median, 92 cm; range, 40-144 cm) t.an in PE (median, 22 cm; range, 0-98 cm; p t.ent. wit. inflammat.ry or miscellaneous diseases or polyposis, t.e diagnost.c yield was not.different.bet.een PE and ant.grade DBE (64% vs. 82% , p = 0.13). However, it.was higher in ant.grade DBE (79% ) t.an in PE (31% , p = 0.012) in nonbleeding pat.ent. wit.out.duodenal pat.ology. In bleeding pat.ent., t.e diagnost.c yield was 40% in ant.grade DBE and 36% in PE (p = 0.61). Conclusions: Ant.grade DBE is superior t. PE in explorat.on of t.e small int.st.ne and in diagnost.c yield for small-int.st.nal pat.ology.

关键词：双气囊小肠镜肠镜检查推进式小肠病变插入长度诊断率息肉病

用EUS探针诊断表浅的食管癌浸润深度:胶冻填充法和水填充气囊法的比较

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世界核心医学期刊文摘（胃肠病学分册） 2006年第8期2卷 26-27页

作者： Esaki M. Mat.umot. t. moriyama t. 陈瑜(译) 郑世成(校) Depart.ent.of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Maidashi 3-1-1 Higashi-ku Fukuoka 812-8582 Japan 不详

Background and Object.ve: Diagnost.c accuracy of probe EUS depends on t.e const.nt.maint.nance of luminal medium for acoust.c coupling. t.is st.dy compared t.e accuracy of probe EUS by a jelly-filled met.od (EUS-J) and by a wat.r-filled balloon met.od (EUS-W) for t.e assessment.of invasion dept. in superficial esophageal cancer. Design and Set.ing: A prospect.ve, single-cent.r st.dy. Pat.ent.: Fort. superficial esophageal cancers in 38 pat.ent.. Int.rvent.ons: Pat.ent. were alt.rnat.ly assigned t. EUS-J or EUS-W. t.e dept. of invasion was classified int. epit.eliumor lamina propria mucosae (D1),muscularis mucosae or superficial layer of t.e submucosa (D2), and deep port.on of t.e submucosa (D3). Depict.on rat., int.robserver variat.on bet.een 2 observers, and accuracy for t.e det.rminat.on of invasion dept. were compared bet.een EUS-J and EUS-W. Main Out.ome Measurement. and Result.: Eight.en cancers were examined by EUS-J, and 22 cancers were examined by EUS-W. t.e act.al dept. of invasion was D1 in 21 cancers, D2 in 9 cancers, and D3 in 10 cancers. Depict.on rat. (94.4% vs 77.2% , P = .14) and int.robserver agreement.of EUS det.rminat.on (82.3% vs 58.8% , P = .13) was higher in EUS-J t.an in EUS-W. t.e overall accuracy for t.e diagnosis of invasion dept. was 77.8% in EUS-J and 59.1% in EUS-W (P = .18). t.e sensit.vit. for t.e diagnosis of D1 cancer was significant.y higher in EUS-J t.an in EUS-W (100% vs 50% , P = .03), while t.e specificit. was not.different.bet.een t.e 2 procedures (81.8% vs 87.5% ). Conclusions: EUS-J is superior t. EUS-W for t.e assessment.of invasion dept. in superficial esophageal cancer, especially for int.amucosal cancer.

关键词：癌浸润深度 EUS 填充法食管癌气囊法诊断探针黏膜下层水单中心研究

Lat.ice Bolt.mann Simulat.ons of Wat.r t.ansport.from t.e Gas Diffusion Layer t. t.e Gas Channel in PEFC

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Communicat.ons in Comput.t.onal Physics 2011年第5期9卷 1206-1218页

作者： Koji moriyama t.kaji Inamuro Fundament.l Research Cent.r Honda R&D Co.Ltd.Saitama 351-0193Japan Depart.ent.of Aeronaut.cs and Ast.onaut.cs Graduate School of EngineeringKyoto UniversityKyoto 606-8501Japan Advanced Research Inst.t.t. of Fluid Science and Engineering Graduate School of EngineeringKyoto UniversityKyoto 606-8501Japan

Wat.r management.is a key t. ensuring high performance and durabilit. of polymer elect.olyt. fuel cell(PEFC),and it.is import.nt.t. underst.nd t.e behavior of liquid wat.r in *** t.is st.dy,t.e t.o-phase lat.ice Bolt.mann met.od is applied t. t.e simulat.ons of wat.r discharge from gas diffusion layers(GDL)t. gas *** GDL is porous media composed of carbon fibers wit. hydrophobic t.eat.ent.and t.e gas channels are hydrophilic micro-scale *** t.e simulat.ons,arbit.arily generat.d porous mat.rials are used as t.e st.uct.res of t.e *** invest.gat. t.e effect. of solid surface wet.abilit.es on wat.r dist.ibut.on in t.e gas channels and t.e ***,t.e result. of X-ray comput.d t.mography images in t.e operat.ng PEFC are compared wit. t.e numerical simulat.ons,and t.e mechanism of t.e wat.r t.ansport.in PEFC is considered.

关键词： t.o-phase lat.ice Bolt.mann met.od polymer elect.olyt. fuel cell X-ray Ct.imaging gas diffusion layer

Direct.act.ng ant.viral agent. against.hepat.t.s C virus and lipid met.bolism

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World Journal of Gast.oent.rology 2017年第31期23卷 5645-5649页

作者： t.t.uo kanda mit.uhiko moriyama division of gast.o-ent.rology and hepat.logy department of medicine nihon university school of medicine

Hepat.t.s C virus (HCV) infect.on induces st.at.sis and is accompanied by mult.ple met.bolic alt.rat.ons including hyperuricemia, reversible hypocholest.rolemia and insulin resist.nce. t.t.l cholest.rol, low-densit. lipoprot.in-cholest.rol and t.iglyceride levels are increased by pegint.rferon and ribavirin combinat.on t.erapy when a sust.ined virologic response (SVR) is achieved in pat.ent. wit. HCV. St.at.sis is significant.y more common in pat.ent. wit. HCV genot.pe 3 but.int.rferon-free regimens are not.always effect.ve for t.eat.ng HCV genot.pe 3 infect.ons. HCV infect.on increases fat.y acid synt.ase levels, result.ng in t.e accumulat.on of fat.y acids in hepat.cyt.s. Of not., low-densit. lipoprot.in recept.r, scavenger recept.r class B t.pe I and Niemann-Pick C1-like 1 prot.ins are candidat. recept.rs t.at.may be involved in HCV. t.ey are also required for t.e upt.ke of cholest.rol from t.e ext.rnal environment.of hepat.cyt.s. Among HCV-infect.d pat.ent. wit. or wit.out.human immunodeficiency virus infect.on, changes in serum lipid profiles are observed during int.rferon-free t.eat.ent.and aft.r t.e achievement.of an SVR. It.is evident.t.at.HCV affect. cholest.rol met.bolism during int.rferon-free regimens. Alt.ough higher SVR rat.s were achieved wit. int.rferon-free t.eat.ent.of HCV, special at.ent.on must.also be paid t. unexpect.d adverse event. based on host.met.bolic changes including hyperlipidemia.

关键词： Cholest.rol Hepat.t.s C virus Int.rferon-free Lipid met.bolism

Exist.nce of aromat.c sp^2 C-H…O = C int.amolecular int.ract.on similar t. hydrogen bond

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Science China Chemist.y 1996年第3期39卷 285-291页

作者： Zeper Abliz Hiroshi moriyama Junji Aoki t.yot.shi Ueda Depart.ent.of Chemist.y Xin Jiang University Urumchi 830046ChinaDepartment of Chemistry Toho University Funabashi Chiba 274 JapanDepartment of Chemistry Toho University Funabashi Chiba 274 JapanDepartment of ChemistryMeisei UniversityHino Tokyo 191 Japan

A ’H NMR signal shift.d drast.cally t. down field (δ - 10.0) at.t.e bay area and in dose proximit. t. C = O group for H-1 was observed t.rough complet. assignment. of 1H NMR spect.a for pyridino- and benzobenzant.rones. It.is concluded t.at.t.is phenomenon is due not.only t. t.e anisot.opy effect.of C=O plus aromat.c ring current.effect. but.also t. t.e elect.ost.t.c at.ract.on of C-H (δ+)…O(δ-)=C int.ract.on. t.e evidence for t.e sp2C-H…O = C int.amolecular int.ract.on similar t. hydrogen bond has also been given by EI-MS and MS/MS (CID) spect.oscopy and IR spect.oscopy, as well as MNDO-PM3 calculat.ons. t.is new kind of int.ract.on might.be called ’quasi-hydrogen bond’.

关键词： polycyclic aromat.c ket.ne pyridinobenzant.rone int.amolecular int.ract.on hydrogen bond quasl-hydrogen bond.

Genome-wide analysis of hepat.t.s B virus int.grat.on in hepat.cellular carcinoma: Insight. next.generat.on sequencing

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Hepat.biliary Surgery and Nut.it.on 2021年第4期10卷 548-552页

作者： Yut.ka Midorikawa Kenji t.t.uno Mit.uhiko moriyama Genome Science and Medicine RCASTUniversity of TokyoTokyoJapan Depart.ent.of Surgery National Center of Neurology and PsychiatryTokyoJapan Depart.ent.of Gast.oent.rology and Hepat.logy Nihon University School of MedicineTokyoJapan

t.e development.of high-t.roughput.sequencing t.chnologies has provided t.e opport.nit. t. plat.orm genome-wide *** applicat.ons of next.generat.on sequencing(NGS)have revealed t.at.t.e hepat.t.s B virus(HBV)genome is randomly int.grat.d t.roughout.t.e human genome in pat.ent. wit. HBV *** t.e induct.on of chronic infect.on of t.e liver,HBV int.grat.on of t.e host.genome cont.ibut.s t. hepat.carcinogenesis,especially in young pat.ent. wit.out.cirrhosis(1,2).

关键词： hepat.t.s pat.ent. int.grat.on

Are direct.act.ng ant.virals against.hepat.t.s C virus infect.on not.associat.d wit. t.e recurrence of hepat.cellular carcinoma?

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Hepat.biliary Surgery and Nut.it.on 2019年第4期8卷 423-425页

作者： Masahiro Ogawa t.t.uo Kanda Mit.uhiko moriyama Division of Gast.oent.rology and Hepat.logy Department of Medicine Nihon University School of Medicine Tokyo Japan

Hepat.t.s C virus (HCV) infect.on is one of t.e major causes of end-st.ge liver disease and hepat.cellular carcinoma (HCC). Before t.e use of direct.act.ng ant.virals (DAAs) against.HCV, liver t.ansplant.t.on was one of t.e best.ways t. achieve long-t.rm survival and a bet.er prognosis in pat.ent. wit. HCV infect.on and advanced liver fibrosis (1). In t.e int.rferon era, it.is difficult.for HCV infect.d pat.ent. wit. advanced liver fibrosis t. achieve sust.ined virological response (SVR) because int.rferon t.erapy causes severe adverse event. and t.ese complet.ly hamper t.is t.eat.ent.in t.ese pat.ent..

关键词： int.rferon infect.on hepat.cellular

2019nCoVR—A comprehensive genomic resource for SARS-CoV-2 variant.surveillance

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t.e Innovat.on 2021年第4期2卷 1-2页

作者： Guoqing Lu Et.uko N.moriyama Depart.ent.of Biology University of Nebraska at OmahaOmahaNE 68182USA School of Biological Sciences and Cent.r for Plant.Science Innovat.on University of Nebraska-LincolnLincolnNE 68588USA

t.e coronavirus disease 2019(COVID-19)is a once-in-a-cent.ry pandemic,and t.e virus,t.e severe acut. respirat.ry syndrome coronavirus 2 or SARS-CoV-2,has infect.d more t.an 180 million people and claimed almost.4 million lives worldwide(as of July 5,2021)since t.e first.case was report.d in Wuhan,China,on December 31,*** China Nat.onal Cent.r for Bioinformat.on(CNCB)responded prompt.y and launched t.e 2019 Novel Coronavirus Resource(2019nCoVR;ht.ps://***/ncov/)in January 2020 for rapid release and public sharing of SARS-CoV-2 genomic dat. and analysis t.ols(Figure 1A).

关键词： Figure prompt VR

Drast.c t.ansit.ons of excit.d st.t. and coupling regime in all-inorganic perovskit. microcavit.es charact.rized by excit.n/plasmon hybrid nat.res

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Light.Science & Applicat.ons) 2022年第1期11卷 79-86页

作者： Shuki Enomot. t.moya t.gami Yusuke Ueda Yut. moriyama Kent.ro Fujiwara Shun t.kahashi Kenichi Yamashit. Facult. of Elect.ical Engineering and Elect.onics Kyoto Institute of TechnologyMatsugasakiSakyo-kuKyoto 606-8585Japan

Lead-halide perovskit.s are highly promising for various opt.elect.onic applicat.ons,including laser ***,fundament.l phot.physics explaining t.e coherent.light.emission from t.is mat.rial syst.m is so int.icat. and oft.n t.e subject.of ***,we syst.mat.cally invest.gat. phot.luminescence propert.es of all-inorganic perovskit. microcavit. at.room t.mperat.re and discuss t.e excit.d st.t. and t.e light.mat.er coupling regime depending on excit.t.on ***-resolved phot.luminescence clearly exhibit. t.at.t.e microcavit. syst.m shows a t.ansit.on from weak coupling regime t. st.ong coupling regime,revealing t.e increase in correlat.d elect.on–hole *** pumping fluence above t.e t.reshold,t.e phot.luminescence signal shows a lasing behavior wit. bosonic condensat.on charact.rist.cs,accompanied by long-range phase *** excit.t.on densit. required for t.e lasing behavior,however,is found t. exceed t.e Mot. densit.,excluding t.e excit.n as t.e excit.d *** result. demonst.at. t.at.t.e polarit.nic Bardeen–Cooper–Schrieffer st.t. originat.s t.e st.ong coupling format.on and t.e lasing behavior.

关键词： pumping coupling regime