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Super.or.antibody and membr.ne pr.tein‑specific T‑cell r.sponses to Cor.naVac by intr.der.al ver.us intr.muscular.r.utes in adolescents

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Wor.d Jour.al of Pediatr.cs 2024年第4期20卷 353-370页

作者： Jaime S.r.sa Duque Samuel M.S.Cheng Car.lyn A.Cohen Daniel Leung Xiwei Wang Xiaofeng Mu Yuet Chung Tsun Ming Lau Manni Wang Wenyue Zhang Yanmei Zhang Howar. H.W.Wong Leo C.H.Tsang Sar. Chaothai Tsz Chun Kwan John K.C.Li Kar. C.K.Chan Leo L.H.Luk Jenson C.H.Ho Wing Yan Li Amos M.T.Lee Jennifer.H.Y.Lam Sau Man Chan Wilfr.d H.S.Wong Issan Y.S.Tam Masashi mori Sophie A.Valkenbur. Malik Peir.s Wenwei Tu Yu Lung Lau Depar.ment of Paediatr.cs and Adolescent Medicine The University of Hong KongHong KongChina School of Public Health The University of Hong KongHong KongChina HKU‑Pasteur.r.sear.h Pole School of Public HealthThe University of Hong KongHong KongChina r.sear.h Institute for.Bior.sour.es and Biotechnology Ishikawa Prefectural UniversityNonoichiJapan Depar.ment of Micr.biology and Immunology Peter Doherty Institute for Infectionand ImmunityUniversity of MelbourneMelbourneVICAustralia Center.for.Immunology and Infection C2i Hong KongChina

Backgr.und Optimising the immunogenicity of COVID-19 vaccines to impr.ve their.pr.tection against disease is *** dosing by intr.der.al(ID)administr.tion has been shown to be equally immunogenic as intr.muscular.IM)administr.tion for.sever.l vaccines,but the immunogenicity of ID inactivated whole sever. acute r.spir.tor. syndr.me cor.navir.s 2(SAr.-CoV-2)at the full dose is *** study(NCT04800133)investigated the super.or.ty of antibody and T-cell r.sponses of full-dose Cor.naVac by ID over.IM administr.tion in *** Par.icipants aged 11–17 year. r.ceived two doses of IM or.ID vaccine,followed by the 3r. dose 13–42 days *** and cellular.immunogenicity outcomes wer. measur.d post-dose 2(IM-CC ver.us ID-CC)and post-dose 3(IMCCC ver.us ID-CCC).Doses 2 and 3 wer. administer.d to 173 and 104 adolescents,*** Spike pr.tein(S)immunoglobulin G(IgG),S-r.ceptor.binding domain(r.D)IgG,S IgG Fcγr.ceptor.IIIa(Fcγr.IIa)-binding,SNM[sum of individual(S),nucleocapsid pr.tein(N),and membr.ne pr.tein(M)peptide pool]-specific inter.eukin-2(IL-2)+CD4^(+),SNM-specific IL-2^(+)CD8^(+),S-specific IL-2^(+)CD8^(+),N-specific IL-2^(+)CD4^(+),N-specific IL-2^(+)CD8^(+)and M-specific IL-2^(+)CD4^(+)r.sponses fulfilled the super.or.and non-infer.or.cr.ter.a for.ID-CC compar.d to IM-CC,wher.as IgG avidity was *** ID-CCC,S-r.D IgG,sur.ogate vir.s neutr.lisation test,90%plaque r.duction neutr.lisation titr.(Pr.T90),Pr.T50,S IgG avidity,S IgG Fcγr.IIa-binding,M-specific IL-2^(+)CD4^(+),inter.er.n-γ+CD8^(+)and IL-2^(+)CD8^(+)r.sponses wer. super.or.and non-infer.or.to *** estimated vaccine efficacies wer. 49%,52%,66%and 79%for.IM-CC,ID-CC,IM-CCC and ID-CCC,*** ID gr.ups r.por.ed mor. local,mild adver.e *** This is the fir.t study to demonstr.te super.or.antibody and M-specific T-cell r.sponses by ID inactivated SAr.CoV-2 vaccination and ser.es as the basis for.futur. r.sear.h to impr.ve the

关键词： Cor.naVac Cor.navir.s disease 2019 Immunity Intr.der.al Vaccine

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Effect of nitr.gen addition on DOC leaching and chemical exchanges on canopy leaves in Guangdong Pr.vince, China

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Jour.al of For.str. r.sear.h 2019年第5期30卷 1707-1713页

作者： Taiki mori Kaijun Zhou Senhao Wang Wei Zhang Jiangming Mo Key Labor.tor. of Vegetation r.stor.tion and Management of Degr.ded Ecosystems South China Botanical GardenChinese Academy of SciencesGuangzhou 510650GuangdongPeople’s Republic of China For.str. and For.st Pr.ducts r.sear.h Institute(FFPr.) TsukubaIbaraki 305-8687Japan Univer.ity of Chinese Academy of Sciences Beijing 100049People’s Republic of China

The impact of nitr.gen(N)deposition on dissolved or.anic car.on(DOC)fr.ctions in thr.ughfall is not well *** per.or.ed a labor.tor. exper.ment and compar.d DOC leaching fr.m canopy leaves after.dipping leaves in pur. water.contr.l)and NH4NO3 solution(N-tr.atment)for.18 *** changes of DOC,NH4^+,NO3^-,SO4^2-,K^+,Mg^2+,Ca^2+and H^+contents after.dipping leaves wer. deter.ined by compar.ng solutions with and without *** r.cor.ed no differ.nces of DOC leaching between contr.l and N-tr.atment,implying that N deposition had minor.impacts on canopy DOC *** confir.ed that pr.vious exper.ments testing the effects of N addition on DOC dynamics without consider.ng the effects of the canopy r.action successfully descr.bed the r.al *** also confir.ed the pr.viously-r.por.ed canopy exchange pr.cess in spite of a high backgr.und N deposition at our.study site.N-tr.atment significantly incr.ased base cation leaching,especially K^+,and the incr.ase was positively cor.elated with foliar.NH4?*** leaching of H^+and SO4^2-was not affected by the N-tr.atment.

关键词： Canopy exchange Dissolved or.anic car.on Nitr.gen deposition Thr.ughfall

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Effects of salinity on the nail-holding power.of dimension lumber.used in light-fr.me wood building

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Jour.al of For.str. r.sear.h 2015年第3期26卷 765-770页

作者： Zeli Que LingYang FeibinWang Xuna Zhu Yongbing Wang Takur. mori College of Mater.als Science and Engineer.ng NanjingForestry University Nanjing 210037 China College of Landscape Ar.hitectur. Nanjing ForestryUniversity Nanjing 210037 China Suzhou Cr.wnhomes Co. LTD. Suzhou 215105 China r.sear.h Institute for.Sustainable Humanospher. (r.SH) Kyoto University Kyoto 6110011 Japan

We studied the effect of salinity on nail-hold- ing power.in wood constr.ction. In saline solution, the holding power.of nails was less than in pur.fied water. With the incr.ase of salt concentr.tion, the sur.ace and side nail- holding power.of the wood specimens both declined, but the differ.nces between salinity tr.atments wer. not sig- nificant. However. compar.d to the sur.ace and side nail- holding power. the power.on the edge was gener.lly less and the differ.nce was not obvious in differ.nt salt con- centr.tions. In the same salt concentr.tion, with the extension of the pr.cessing cycle, the per.or.ance of holding power.of nails showed a downwar. tr.nd, expect the tempor.r. r.se in the middle.

关键词： Nail-holding power Salinity Mechanicalpr.per.ies Dimension lumber Joints

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Swells of the East China Sea

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Jour.al of Ocean Univer.ity of China 2017年第4期16卷 674-682页

作者： TAO Aifeng YAN Jin PEI Ye ZHENG Jinhai mori Nobuhito Key Labor.tor. of Coastal Disaster.and Defence(Hohai Univer.ity) Ministry of EducationNanjing 210098P.R.China College of Har.or Coastal and Offshore EngineeringHohai UniversityNanjing 210098P.R.China Xiangshui Yangtze Wind Power.Gener.tion Co. LtdXiangshui 224600P.R.China Disaster.Pr.vention r.sear.h Institute Kyoto UniversityGokashoUjiKyoto 611-0011Japan

Over.the past few decades,an incr.asing number.of mar.ne activities have been conducted in the East China Sea,including the constr.ction of var.ous mar.ne str.ctur.s and the passage of lar.e *** safety issues ar. par.mount and ar. becoming mor. impor.ant with r.spect to the likely incr.ase in size of ocean waves in r.lation to global climate change and associated *** addition,swells also can be ver. danger.us because they induce the r.sonance of floating str.ctur.s,including *** study focuses on an investigation of swells in the East China Sea and uses hindcast data for.waves over.the past 5 year. in a numer.cal model,WAVEWATCH III(WW3),together.with histor.cal climate *** numer.cal calculation domain cover. the entir. Nor.h West ***,swells ar. separ.ted and analyzed using simulated wave fields,and both the char.cter.stics and gener.tion mechanisms of swells ar. investigated.

关键词： swell East China Ocean numer.cal simulation

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Exper.mental Study of Heating Fluid between Two Concentr.c Cylinder. with Cavities

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Jour.al of Ther.al Science 2008年第2期17卷 175-180页

作者： Hir.mitsu HAMAKAWA Hir.yuki mori Makoto IINO Masaaki HOr. Mizuho YAMASAKI Toshiaki SETOGUCHI Depar.ment of Mechanical Engineer.ng Oita University EBAr. Kyushu Co. Ltd. Fanuc LTD Kawasaki Heavy Industr.es Ltd. Depar.ment of Mechanical Engineer.ng Saga University

In this paper. we ar. concer.ed with the heating fluid in the annular.space between two concentr.c cylinder. wher. the inner.cylinder.with cavities is r.tated and the outer.cylinder.is at r.st. The effects of cavities of the inner.cylinder.on the heating fluid and the cavitation behavior.ar. examined. We measur.d the flow r.te, r.tating speed of r.tor. fr.ction tor.ue, temper.tur. r.se and pr.ssur. dr.p between inlet and outlet of this device. The flow r.te of water.r.nged fr.m 0.42×10^-4 to 4.59×10^-4 ma/s at the inlet. The fr.ction tor.ue and the quantity of heat of the inner.cylinder.with cavities wer. lar.er.than the case of no cavities, and they incr.ased as the r.tating speed of inner.cylinder.incr.ased. The efficiency was close to about 1 as the r.tating speed of inner.cylinder.incr.ased. The behavior.of cavitation in the cavity on the sur.ace of inner.cylinder.was discussed.

关键词： Viscous Flow Shear.Flow Concentr.c Annulus Cavity Fr.ctional Heating Cavitation

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Influence of Additive Gas on Electr.cal and Optical Char.cter.stics of Non-equilibr.um Atmospher.c Pr.ssur. Ar.on Plasma Jet

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Plasma Science and Technology 2011年第5期13卷 575-582页

作者：费小猛 Shin-ichi KUr.DA Yuki KONDO Tamio mori Katsuhiko HOSOI Depar.ment of Advanced Pr.duction Science and Technology Graduate School of EngineeringGunma University Cr.sur.Cor.or.tion

Electr.cal and optical pr.per.ies of an ar.on plasma jet wer. char.cter.zed. In par.icular. effects of an additive gas, namely nitr.gen or.oxygen, on these pr.per.ies wer. studied in detail. The plasma jet was found to be of a glow-like dischar.e, which scar.ely changed upon the injection of an additive gas, either.dir.ctly or.thr.ugh a glass capillar.. Optical emission spectr.scopy char.cter.zation r.vealed that excited ar.on atoms wer. the pr.dominant active species in this plasma jet. Metastable ar.on atoms wer. highly quenched, and N2（C3yIu） became the main ener.y car.ier.following nitr.gen injection. When oxygen was added to the after.low zone thr.ugh a glass capillar., no significant quenching effect was obser.ed and the number.of oxygen atoms decr.ased with the incr.ase in oxygen concentr.tion. Finally, to demonstr.te an application of this plasma jet, a high-density polyethylene sur.ace was tr.ated with ar.on, ar.on/nitr.gen, and ar.on/oxygen plasmas.

关键词： atmospher.c pr.ssur. Ar.plasma jet additive gas dischar.e optical emission spectr.scopy

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新型超高强度钢零件热冲压技术(英文)

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中国有色金属学会会刊：英文版 2012年第S2期22卷 496-503页

作者： Ken-ichir. mori Depar.ment of Mechanical Engineer.ng Toyohashi University of Technology

为克服现今热冲压的难题,开发了一种高强度钢零件的新型热冲压技术。利用快速电阻加热,该热冲压技术所需的设备比电炉加热的设备更简单。与传统液压加工相比,该工艺采用机械伺服高速冲压可以提高成形性。通过具有局部旁路电阻加热的剪... 详细信息

为克服现今热冲压的难题,开发了一种高强度钢零件的新型热冲压技术。利用快速电阻加热,该热冲压技术所需的设备比电炉加热的设备更简单。与传统液压加工相比,该工艺采用机械伺服高速冲压可以提高成形性。通过具有局部旁路电阻加热的剪切模具,制备了具有不同强度分布的零件。局部电阻加热使得剪切区的流变应力减小,从而使模具淬火钢零件和超高强钢板的剪切更容易。通过对杯壁进行电阻加热,利用热齿键成型技术制备了超高强度钢齿轮盖。同时,还通过热冲压成型制备了汽车用中空导流槽。一次热压成形工艺包括电阻加热、成形、剪切和模具冷却等流程,该工艺适用于相对较小的高强度钢零件。

关键词：热冲压超高强度钢模具淬火剪切模淬火齿键成型管成型一次成型

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Analysis of Factor. Influencing the Pur.hase Intention of Cr.ss-bor.er.E-commer.e Platfor. Customer. in Lat in Amer.ca

Analysis of Factors Influencing the Purchase Intention of Cr...

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作者： mori HAr.LD 上海财经大学

学位级别：硕士

随着拉丁美洲国家经济和互联网技术的不断发展,拉丁美洲国家的跨境电子商务发展的如火如荼。跨境电子商务在促进消费升级方面具有巨大作用,消费者的购买意愿是本文的主要研究对象,拉丁美洲国家电子商务的发展可以促进当地经济的发展,因... 详细信息

随着拉丁美洲国家经济和互联网技术的不断发展,拉丁美洲国家的跨境电子商务发展的如火如荼。跨境电子商务在促进消费升级方面具有巨大作用,消费者的购买意愿是本文的主要研究对象,拉丁美洲国家电子商务的发展可以促进当地经济的发展,因此研究影响拉丁美洲国家电子商务系统中顾客购买意愿的因素具有一定的现实意义。本文通过实证分析法分析了影响拉丁美洲国家跨境电子商务系统中顾客购买意愿的因素。本文首先通过跨境网络购物平台使用影响因素对跨境网络购物平台使用意愿的作用假设、跨境网络购物平台使用意愿对购买行为的作用假设、跨境网络购物平台使用意愿的中介作用假设、理论模型构建四个方面对研究假设和理论模型进行阐述;然后通过问卷调查基本内容、数据收集、样本描述三个方面对问卷设计与调查进行阐述;最后通过量表的信效度分析、描述性统计分析、相关分析、回归分析、网络购物使用意愿的中介效应分析五个方面对统计分析与假设检验进行阐述。本文得出的结论是:感知产品质量、感知服务质量正向作用于跨境网络购物平台使用意愿;感知风险负向作用于跨境网络购物平台使用意愿;购买价格与网络使用购买意愿的作用不显著;网络购物使用意愿具有一定的中介作用。然后通过实证分析的结果提出了一些改善拉丁美洲国家跨境电商体系,提高顾客购买意愿的政策建议。我希望本文中的政策建议可以为拉丁美洲国家跨境电子商务系统的发展提供借鉴作用。

关键词：拉丁美洲国家跨境电子商务系统客户的购买意愿

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High-speed unsteady flows past two-body configur.tions

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Chinese Jour.al of Aer.nautics 2018年第1期31卷 54-64页

作者： Xiaopeng XUE Yusuke NISHIYAMA Yoshiaki NAKAMUr. Koichi mori Yunpeng WANG ChihYung WEN School of Aer.nautics and Astr.nautics Central South University Depar.ment of Aer.space Engineer.ng Nagoya University Institute of Mechanics Chinese Academy of Sciences Depar.ment of Mechanical Engineer.ng The Hong Kong Polytechnic University

This paper.pr.sents a detailed investigation of unsteady super.onic flows ar.und a typical two-body configur.tion, which consists of a capsule and a canopy. The cases with differ.nt tr.iling distances between the capsule and canopy ar. simulated. The objective of this study is to examine the detailed effects of tr.iling distance on the flow fields and analyze the flow physics of the differ.nt flow modes ar.und the par.chute-like two-body model. The computational r.sults show unsteady pulsating flow fields in the small tr.iling distance cases and ar. in r.asonable agr.e- ment with the exper.mental data. As the tr.iling distance incr.ases, this unsteady flow mode takes differ.nt for.s along with the wake/shock and shock/shock inter.ctions, and then gr.dually fades away and tr.nsits to oscillate mode, which is ver. differ.nt fr.m the for.er. As the tr.iling distance keeps incr.asing, only the capsule wake/canopy shock inter.ction is pr.sent in the flow field ar.und the two-body model, which r.veals that the unsteady capsule shock/canopy shock inter.ction is a key mechanism for.the pulsation mode.

关键词： Compr.ssible flow Shock/shock inter.ction Two-body configur.tions Unsteady flow Wake/shock inter.ction

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Topical application of glycyr.hizin pr.par.tion amelior.tes exper.mentally induced colitis in r.ts

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Wor.d Jour.al of Gastr.enter.logy 2011年第17期17卷 2223-2228页

作者： Tomohir. Kudo Shinichi Okamur. Yajing Zhang Takashige Masuo Masatomo mori Depar.ment of Medicine and Molecular.Science Gunma University Graduate School of Medicine Gunma 371-8511 Japan Depar.ment of Medical Infor.atics and Decision Sciences Gunma University School of Medicine Gunma 371-8511 Japan

AIM:To examine the efficacy of glycyr.hizin pr.par.tion(GL-p) in the tr.atment of a r.t model of ulcer.tive colitis(UC).METHODS:Exper.mental colitis was induced by or.l administr.tion of dextr.n sodium *** with colitis wer. intr.r.ctally administer.d GL-p or.*** extent of colitis was evaluated based on body weight gain,colon wet weight,and macr.scopic damage *** expr.ssion levels of pr.-inflammator. cytokines and chemokines in the inflamed mucosa wer. measur.d by cytokine antibody ar.ay *** effect of GL-p on myeloper.xidase(MPO) activity in the inflamed mucosa and pur.fied enzyme was ***:GL-p tr.atment significantly amelior.ted the extent of colitis compar.d to sham tr.atment with *** antibody ar.ay analysis showed that GL-p tr.atment significantly decr.ased the expr.ssion levels of pr.-inflammator. cytokines and chemokines,including inter.eukin(IL)-1β,IL-6,tumor.necr.sis factor.α,cytokine-induced neutr.phil chemoattr.ctant-2,and monocyte chemoattr.ctant pr.tein-1 in the inflamed ***,GL-p inhibited the oxidative activity of mucosal and pur.fied ***:GL-p enema has a ther.peutic effect on exper.mental colitis in r.ts and may be useful in the tr.atment of UC.

关键词： Glycyr.hizin Colitis Dextr.n sodium sulfate Ulcer.tive colitis Cytokine Chemokine Pr.tein ar.ay Myeloper.xidase Enema Car.oxymethylcellulose

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