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Development of a sensor for the detection of Escherichia coli in brackish waters

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Journal of Coastal Life Medicine 2016年第3期4卷 200-202页

作者： Mancuso monique Grossi Marco Rappazzo Alessandro Ciro Zaccone Renata Caruso Gabriella RiccòBruno Bergamasco Alessandro Institute for Coastal Marine Environment(IAMC-CNR)-Section of Messina Spianata S.Raineri 8698122Italy Department of Electronic Engineering(D.E.I.S.)Bologna-University of Bologna Via Zamboni 3340126 BolognaItaly

Monitoring of bacterial pathogens is important for marine environmental protection,because the presence of these microorganisms can be a serious risk for human *** this reason,a portable sensor implemented as an electronic embedded system featuring disposable measurement cells was used to evaluate the ability and sensitivity of detection of Escherichia coli(***)as an indicator of fecal pollution in transitional environments and a water sample added with ***(10^(2) CFU/mL)was *** first result obtained from the laboratory experiment seems promising for the determination of *** in environmental samples,though further improvements will be needed for the field application of this sensor in marine and brackish waters.

关键词： Monitoring Waters Escherichia coli Portable sensor Fecal pollution Environment

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抵制霉菌毒素对动物的危害

国外畜牧学（猪与禽） 2013年第6期33卷 20-22页

作者：侯梅利 monique Baecke 比利时Nutriad公司

霉菌毒素会给动物健康和生产性能带来风险,因此管理和控制霉菌毒素对降低这些有害效应是非常必要的。由于动物日粮污染的霉菌毒素通常是多种多样的,因此引起的不良影响也有所不同。这就需要用一种综合方法来消除这些霉菌毒素带来的不良... 详细信息

霉菌毒素会给动物健康和生产性能带来风险,因此管理和控制霉菌毒素对降低这些有害效应是非常必要的。由于动物日粮污染的霉菌毒素通常是多种多样的,因此引起的不良影响也有所不同。这就需要用一种综合方法来消除这些霉菌毒素带来的不良影响。

关键词：霉菌毒素动物健康危害有害效应动物日粮生产性

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人剪切题蛋白FBP21的结构与功能研究

生物物理学报 2009年第S1期25卷 333-334页

作者：黄小娟 monique Beullens 张家海周毅吴季辉 Mathieu Bollen 施蕴渝中国科学技术大学生命科学院合肥微尺度物质国家实验室 Laboratory of Biosignaling and Therapeutics Department of Molecular Cell BiologyFaculty of MedicineKULeuvenLeuvenBelgium

人剪切体相关蛋白 FBP21(Formin binding protein 21)是剪切体复合物 A/B 的组成部分并与 U2 snENP(小核糖核蛋白)相互作用(1)。FBP21 含有一个 matrin-type

关键词： FBP21 WW 结构域前体 mRNA 剪切蛋白质溶液结构

Assessment of Vulnerability to Groundwater Pollution in the Lobo Watershed at Nibéhibé(Central-West, Côte d’Ivoire)

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Journal of Water Resource and Protection 2020年第8期12卷 657-671页

作者： Yiwa monique Kamenan Oi Mangoua Jules Mangoua Brou Dibi Sampah Eblin Georges Kouakou Lazare Kouassi Kouamé Auguste Kouassi Laboratory of Science and Technology of Environment Jean Lorougnon Guédé University Daloa C&ocirc te d’Ivoire Laboratory Geosciences et Environment Nangui Abrogoua University Abidjan C&ocirc te d’Ivoire

Drinking water supply to people in rural areas is increasingly oriented towards the search for groundwater. However, these resources, which were once of good quality, are currently threatened by various sources of pollution points and diffuse. The objective of this study is to map the intrinsic vulnerability to groundwater pollution of the Lobo watershed in Nibéhibé. The intrinsic vulnerability mapping method, PaPRIKa adapted or PaPRI which acronym is the protection of aquifers (Pa) based on three criteria: P for protection, R for rock type, I represents infiltration was used. The results show three (3) vulnerability classes, which are moderate, high and very high. This map shows that the high vulnerability class (89%) dominates the study area. This predominance shows that the groundwater of the Lobo watershed is at high risk of pollution.

关键词： Pollution Groundwater Vulnerability PaPRI Côte d’Ivoire

问题在司来吉林还是在过早中止其临床试验此临床问题尚未有而且很可能永不会有理想答案

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英国医学杂志中文版 1998年第3期1卷 100-101页

作者： monique M B Breteler 冯颖 Assistant professor of neuroepidemiology Department of Epidemiology and Biostatics Erasmus University Medical School3000DR Rotterdamthe Netherlands

帕金森病是仅次于痴呆之后,位居第二的最常见的神经变性疾病。55岁及以上人群中约1.4%患帕金森病,且由于西方国家人口老龄化程度的提高,此类患者绝对数正在迅速增长。迄今,主要是对症治疗,但正在努力开发阻止疾病进展、甚至治愈该病的... 详细信息

帕金森病是仅次于痴呆之后,位居第二的最常见的神经变性疾病。55岁及以上人群中约1.4%患帕金森病,且由于西方国家人口老龄化程度的提高,此类患者绝对数正在迅速增长。迄今,主要是对症治疗,但正在努力开发阻止疾病进展、甚至治愈该病的神经保护剂。显然。

关键词：帕金森病神经变性疾病临床试验神经保护剂左旋多巴居第西方国家治疗者人口老龄化程度嗅隐亭

替代R113的铁路设备电力电子器件冷却液的研究

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大功率变流技术 1994年第9期 22-26页

作者： monique LALLEMAND 田自金

蒙特利尔协议和伦敦会议宣告,到2000年氟里昂R113将被全面禁止使用,在此之前必须为它寻找代用品。本文对铁路设备的电力电子器件冷却液的性能进行了分析研究,并对几种研究的替代液性能作了评价。

关键词：电力电子器件冷却液性能研究

Tailoring lifestyle programmes for diabetes prevention for US South Asians

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Family Medicine and Community Health 2020年第2期8卷 12-20页

作者： Mary Beth Weber monique M Hennink K M Venkat Narayan Hubert Department of Global Health Emory UniversityAtlantaGeorgiaUSA

Objective The purpose of this study was to develop and test the feasibility of a culturally tailored Diabetes Prevention Programme(DPP)for US South Asians,a large population with high diabetes *** The South Asian Health and Prevention Education(SHAPE)study included:(1)focus group discussions with South Asian adults to understand views of lifestyle behaviours and diabetes prevention;(2)modification of the US DPP for South Asians and(3)a pilot,pre-post study to test the feasibility and impact of delivering the culturally tailored *** The study was conducted in Atlanta,Georgia,*** group discussions and intervention classes were held at locations within the community(eg,South Asian restaurants,a public library,university classrooms,a South Asian owned physical therapy studio).Participants The focus group discussions(n=17 with 109 individuals)included adults aged 25 years of older who self-identified as South *** were stratified by age(25-40 years or older than 40 years)and *** SHAPE pilot study included 17(76.5%male with a mean age of 46.9±12 years)South Asian adults aged 25 years or older with pre-diabetes and body mass index(BMI)>22 kg/*** Formative data from 17 focus group discussions and a community board guided the modification of the DPP curriculum to reflect cultural food preferences and include tools to leverage social support,create a stronger foundation in exercise and overcome culturally specific *** SHAPE pilot study included 17 South Asian adults with pre-diabetes and BMI>22 kg/*** were positive changes in participants’weight,waist circumference,blood pressure,plasma lipids,HbA1c and other cardiometabolic markers postintervention and 55%of participants regressed to *** These results provide important information on the barriers faced by US South Asians in participating in‘standard’lifestyle change programs,indicate the feasibility of culturally tailored programmes and show p

关键词： prevention discussions overcome

Overexpression of the Six1 Homeobox Gene Is Associated with Diffuse Peritoneal Spread and Larger Residual Disease after Maximal Cytoreductive Effort in Advanced Ovarian Cancer

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Journal of Cancer Therapy 2015年第14期6卷 1167-1175页

作者： Julia R. Embry-Schubert Lubna Qamar monique Spillman Michael G. Kelly Susan A. Davidson Kian Behbakht Department of Obstetrics and Gynecology Kaiser-Permanente Denver CO USA Division of Gynecologic Oncology Department of Obstetrics and Gynecology University of Colorado School of Medicine and Anschutz Medical Campus Aurora CO USA Texas Oncology Sammons Cancer Center Baylor University Medical Center Dallas TX USA Wake Forest University School of Medicine One Medical Center Boulevard Winston-Salem NC USA Denver Health Medical Center Denver CO USA

Study Design: Between January 2003 and June 2009, we collected fresh tumor and extracted high-quality RNA from the omental/peritoneal metastases of 47 patients with stage IIB-IV ovarian cancer. Clinical data were abstracted from the patients’ medical records. Expression of Six1 level by quantitative RT-PCR was compared with preoperative factors and intraoperative findings using the χ2 test and the Fisher exact test. The effect of Six1 elevation on survival was assessed with the Kaplan/Meier method. Results: The mean age of patients enrolled was 60 (range 33 - 84). The histological subtypes were 77% serous (36/47), 11% endometrioid (5/47), 4% mucinous (2/47), and 4% clear cell (2/47). Eighty-one percent were optimally cytoreduced. Median Six1 expression for the samples was 114 fg/ng 18S rRNA and Six1 overexpression, defined as >300 fg/ng 18S rRNA, was observed in 19% of tumors. Six1 expression above sample median was associated with peritoneal disease (p = 0.049) and inability to optimally cytoreduce (p = 0.02). Six1 overexpression was associated with worsened survival in the high grade serous subgroup (43 months versus 71 months, p = 0.039 Log Rank test). Conclusions: Elevated levels of Six1 predict peritoneal disease and larger residual tumor after maximal cytoreductive effort. Prospective prediction of surgical cytoreduction using a combination of Six1 expression, included with other factors, is currently being evaluated.

关键词： Ovarian Cancer Homeobox Genes Six1 Cytoreduction

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基于红外图像的手关节区域自动提取

北京生物医学工程 2012年第2期31卷 130-133,177页

作者：秦畅卞春华 monique Frize 南京大学电子科学与工程学院南京210093 School of Information Technology and Engineering University of Ottawa

目的手工选取关节区域的诊断方式增加了关节类疾病诊断的主观性和工作量。针对这一问题本文提出一种自动定位红外图像中人手关节的方法。方法根据人手的解剖学结构和手部特征点的位置,提出自动提取手关节区域的3种模型,即四边形模型、... 详细信息

目的手工选取关节区域的诊断方式增加了关节类疾病诊断的主观性和工作量。针对这一问题本文提出一种自动定位红外图像中人手关节的方法。方法根据人手的解剖学结构和手部特征点的位置,提出自动提取手关节区域的3种模型,即四边形模型、椭圆形模型和圆形模型,其中手部特征点包括目前手部图像研究中常用的11个特征点,以及本文新提出的2个辅助特征点。最后,通过一种基准图像比较方法验证本文方法的有效性。结果使用该方法能够准确找到关节中心的位置,在红外图像中自动定位出手部关节区域。结论该关节区域自动提取算法有助于关节定位及疾病诊断。

关键词：兴趣区域红外图像人手定位掌指关节