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Roles of Ubiquitination in the Control of Phosphate Starvation Responses in Plants

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Journal of Integrative Plant Biology 2013年第1期55卷 40-53页

作者： Mónica rojas-triana Regla Bustos Ana Espinosa-Ruiz Salom Prat Javier Paz-Ares Vicente Rubio The Samuel Roberts Noble Foundation Department of Plant Biology 2510 Sam Noble Parkway Ardmore CBGP (INIA-UPM) Departamento de Biotecnología Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria Campus de Montegancedo Centro Nacional de Biotecnología (CNB-CSIC) Darwin

Throughout evolution, plants have evolved sophisticated adaptive responses that allow them to grow with a limited supply of phos-phate, the preferential form in which the essential macronutrient phosphorus is absorbed by plants. Most of these responses are aimed to increase phosphate availability and acquisition through the roots, to optimize its usage in metabolic processes, and to protect plants from the deleterious effects of phosphate deficiency stress. Regulation of these adaptive responses requires fine percep- tion of the external and internal phosphate levels, and a complex signal transduction pathway that integrates information on the phosphate status at the whole-plant scale. The molecular mecha-nisms that participate in phosphate homeostasis include transcriptional control of gene expression, RNA silencing mediated by microRNAs, regulatory non-coding RNAs of miRNA activity, phosphate transporter trafficking, and post-translational modification of proteins, such as phosphorylation, sumoylation and ubiquitination. Such a varied regulatory repertoire reflects the complexity intrinsic to phosphate surveying and signaling pathways. Here, we describe these regulatory mechanisms, emphasizing the increasing importance of ubiquitination in the control of phosphate starvation responses.

关键词： Phosphate homeostasis phosphate signaling phosphate starvation post-translational control ubiquitin.

Intraductal papillary neoplasm of the bile ducts: A case report and literature review

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World Journal of Gastroenterology 2015年第43期21卷 12498-12504页

作者： Yaohong Tan Clara Milikowski Yanelba Toribio Adam Singer Claudia P rojas monica T Garcia-Buitrago Department of Pathology Jackson Memorial HospitalUniversity of Miami Miller School of Medicine Department of Radiology Jackson Memorial HospitalUniversity of Miami Miller School of Medicine

Intraductal papillary neoplasm of the bile duct(IPNB) is a rare bile duct neoplasm mostly found in far eastern nations where hepatolithiasis and clonorchiasis infections are endemic. In western countries,it is very rare and the etiology is unknown. In this article,we report the first IPNB patient we encountered in our clinic and a literature review. The patient is a 38-yearold female with a history of choledocholithiasis who presented with obstructive jaundice. She was found to have a papillary mass at the junction of the right hepatic duct and common hepatic duct with six masses in the liver parenchyma. The immunophenotypic and histologic features of the tumor are consistent with IPNB,gastric subtype. The patient had a partial hepatectomy and has been receiving palliative chemotherapy. In a search of Pub Med database,we collected 354 IPNB patients reported in 22 articles. In these patients,52.8% were from Japan and 27.7% were from western countries including the United States(11.0%). The age of the patients ranged from 35 to 80 years old with an average of 64.6. Male/female ratio was 1.5. Macroscopically,57.5% of the tumors were in the left lobe and 29.5% were in the right lobe. The average size of the tumor were 4.2 cm at the time of diagnosis. Histologically,pancreato-biliary subtype accounted for 41.8%,intestinal 28.0%,gastric 13.5% and oncocytic 16%. An invasive component is most often present in the pancreato-biliary and gastric subtypes. Despite recent advanced technologies,diagnosis of IPNB is still challenging,especially in western countries due to its rarity. Defined clinicopathologic features are in demand for the accurate diagnosis and proper treatment.

关键词： Intraductal papillary neoplasm Mucinous cystic neo

An Approach to Design MIMO FO Controllers for Unstable Nonlinear Plants

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IEEE/CAA Journal of Automatica Sinica 2016年第3期3卷 338-344页

作者： Arturo rojas-Moreno IEEE Department of Electrical Engineering Universidad de Ingenieriay Tecnologia (www.utec.edu.pe)

This paper develops an approach to control unstable nonlinear multi-inputs multi-output(MIMO) square plants using MIMO fractional order(FO) controllers. The controller design uses the linear time invariant(LTI) state space representation of the nonlinear model of the plant and the diagonal closedloop transfer matrix(TM) function to ensure decoupling between inputs. Each element of the obtained MIMO controller could be either a transfer function(TF) or a gain. A TF is associated in turn with its corresponding FO TF. For example, a D(Derivative) TF is related to a FO TF of the form Dδ, δ =[0, 1]. Two applications were performed to validate the developed approach via experimentation: control of the angular positions of a manipulator, and control of the car and arm positions of a translational manipulator.

关键词： Fractional calculus modeling of nonlinear sys-tem control of manipulator multivariable decoupling multivari-able nonlinear system

Physicochemical properties of Li_(3)Ba_(2)La_(3)(MoO_(4))_(8):Eu,Tb red-emitting phosphor for solid state white lamps

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Journal of Rare Earths 2023年第9期41卷 1279-1287,I0001页

作者： Kora Lu rojas Baldivia Gustavo A.Hirata Center for Scientific Research and Higher Education of Ensenada Ensenada Baja California 22860Mexico Center for Nanoscience and Nanotechnology National Autonomous University of Mexico EnsenadaBaja Califomia 22860Mex

In this work,combustion synthesis was used for the first time to fabricate a phosphor material with red emission for applications in solid-state white-light *** synthesized a material with emission wavelength at λ_(em)=617 nm,excited under long UV-blue wavelength based on Eu^(3+),Tb^(3+)-activated molybdates Li_(3)Ba_(2)(La_(1-x-y)Eu_(x)Tb_(y))_(3)(MoO_(4))_(8) with 0 ≤ x ≤1 and 0 ≤ y ≤ 1.A series of powder samples were produced by the combustion method and post-annealed at 800℃ in *** crystalline phase formation was investigated by X-ray diffraction,which reveals the monoclinic C2/c(15) space *** is observed that crystalline structure and morphology are preserved when the host lattice is doped with Eu^(3+) or Tb^(3+) single ions and co-doped with both ions at different doping concentrations.A detailed characterization by scanning electron microscopy(SEM) and transmission electron microscopy(TEM)shows a similar morphology in all samples:rather large(1-7 μm) agglomerate particles with irregular shapes and surrounded by smaller nanoparticles of 50 nm in ***-visible absorption spectra confirm the presence of Eu^(3+) and Tb^(3+) *** luminescent properties of the obtained phosphors were studied in *** measurements indicate that the best emission intensity is for Eu^(3+):Tb^(3+)doping ratios of 80:0,90:0 and 20:*** the other hand,samples with 80:0,60:40,and 20:80 doping ratios show the highest intensity in a detailed photoluminescence analysis and they exhibit the highest quantum yield values.A complete and efficient energy transfer from the sensitizer Tb^(3+) to the activator Eu^(3+) is observed in all co-doped phosphors post-annealed at 800℃ for 4 ***,the Li_(3)Ba_(2)La_(3)(MaO_(4))_(8):Eu^(3+),Tb^(3+) materials fabricated by combustion synthesis are excellent phosphors for being applied as red-emitting component in solid-state white-light lamps due to an improved color rendering index(CRI) that can be obtained under lo

关键词： Molybdate Europium Terbium Luminescence Phosphor-converted LED Rare earths

Estimation of the behavior factor of existing RC-MRF buildings

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Earthquake Engineering and Engineering Vibration 2018年第1期17卷 191-204页

作者： Marco Vona monica Mastroberti School of Engineering University of Basilicata

In recent years, several research groups have studied a new generation of analysis methods for seismic response assessment of existing buildings. Nevertheless, many important developments are still needed in order to define more reliable and effective assessment procedures. Moreover, regarding existing buildings, it should be highlighted that due to the low knowledge level, the linear elastic analysis is the only analysis method allowed. The same codes（such as NTC2008, EC8） consider the linear dynamic analysis with behavior factor as the reference method for the evaluation of seismic demand. This type of analysis is based on a linear-elastic structural model subject to a design spectrum, obtained by reducing the elastic spectrum through a behavior factor. The behavior factor（reduction factor or q factor in some codes） is used to reduce the elastic spectrum ordinate or the forces obtained from a linear analysis in order to take into account the non-linear structural capacities. The behavior factors should be defined based on several parameters that influence the seismic nonlinear capacity, such as mechanical materials characteristics, structural system, irregularity and design procedures. In practical applications, there is still an evident lack of detailed rules and accurate behavior factor values adequate for existing buildings. In this work, some investigations of the seismic capacity of the main existing RC-MRF building types have been carried out. In order to make a correct evaluation of the seismic force demand, actual behavior factor values coherent with force based seismic safety assessment procedure have been proposed and compared with the values reported in the Italian seismic code, NTC08.

关键词： seismic behavior existing buildings seismic safety assessment behavior factor

Non-perturbative multiphoton excitation studies in an excitonic coupled quantum well system using high-intensity THz laser fields

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Chinese Physics B 2019年第8期28卷 355-363页

作者： monica Gambhir Vinod Prasad Department of Physics Swami Shraddhanand CollegeUniversity of DelhiDelhi 110036India Departmento de Quimica Universidad Autonoma MetropolitansSan Rafael Atlixco No186IztapalapaMexico DF 09340Mexico

Multiphoton excitations and nonlinear optical properties of exciton states in GaAs/AlxGa1-xAs coupled quantum well structure have been theoretically investigated under the influence of a time-varying high-intensity terahertz(THz)laser ***-perturbative Floquet theory is employed to solve the time-dependent equation of motion for the laser-driven excitonic quantum well *** response to the field parameters,such as intensity and frequency of the laser electric field on the state populations,can be used in various optical semiconductor device applications,such as photodetectors,sensors,all-optical switches,and terahertz emitters.

关键词： quantum well excitons terahertz non-perturbative multiphoton laser Floquet

On Standard Invariants of Bi-polymatroidal Ideals

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Algebra Colloquium 2014年第2期21卷 267-274页

作者： monica La Barbiera University of Messina Department of'Mathematics Viale Ferdinando Stagno d'Aleontres 31 98166 Messina Italy

The standard invariants of the bi-polymatroidal ideals of Veronese type are computed.

关键词： bi-polymatroidal ideals linear quotients

Antibacterial chitosan-Dioscorea alata starch film enriched with essential oils optimally prepared by following response surface methodology

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Food Bioscience 2022年第2期46卷 912-922页

作者： Annisa Istiqomah Maryam Rahmi Utami Maulidan Firdaus Venty Suryanti triana Kusumaningsih Master Program of Chemistry Faculty of Mathematics and Natural SciencesSebelas Maret UniversityJl.Ir.Sutami No.36ASurakarta57126Indonesia Department of Chemistry Faculty of Mathematics and Natural SciencesSebelas Maret UniversityJl.Ir.Sutami No.36ASurakarta57126Indonesia

Numerous endeavours have been developed bio-based polymer packaging films to replace the use of petroleum-based *** this study,as a response and support to the enduring research issues,we have developed the optimization composite film formulation based on chitosan(2%),Dioscorea alata starch(0.5%),and glycerol(1.5%)had satisfactory result on several parameters consisting thickness(0.45 mm),solubility(472.1%),moisture content(29.872%),biodegradability(38.346%),elastic modulus(971.2 N/m2)and tensile strength(98.71 N/m).Further,the optimized chitosan film(CF)formulation was enriched with several essential oils(EO),i.e.,lemongrass,garlic and aloe vera *** the addition of EO,the solubility,biodegradable tests,and elongation to break of CF tended to decrease whereas the contact angle and mechanical properties significantly ***,the antibacterial properties of CF against Escherichia coli,Salmonella typhi,Staphylococcus aureus and Staphylococcus epidermidis dramatically increased by the addition of *** impressive results are expected to be applied in the food packaging industry to maintain the quality of food products.

关键词： Chitosan-based film Box-behnken design Food package Response surface methodology

Gallstones in patients with liver cirrhosis:Incidence,etiology,clinical and therapeutical aspects

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World Journal of Gastroenterology 2014年第23期20卷 7277-7285页

作者： monica Acalovschi 3~(rd) Medical Clinic University of Medicine and Pharmacy400162 Cluj-NapocaRomania

Gallstones occur in about one third of the patients having liver *** gallstones are the most frequent type,while cholesterol stones represent about15%of all stones in *** secretion of unconjugated bilirubin,increased hydrolysis of conjugated bilirubin in the bile,reduced secretion of bile acids and phospholipds in bile favor pigment lithogenesis in *** hypomotility also contributes to *** most recent data regarding risk factors for gallstones are *** prevalence increases with age,with a ratio male/female higher than in the general *** alcoholism,viral C cirrhosis,and non-alcoholic fatty liver disease are the underlying liver diseases most often associated with *** are often asymptomatic,and discovered *** asymptomatic,expectant management is recommended,as for asymptomatic gallstones in the general ***,a closer follow-up of these patients is necessary in order to earlier treat symptoms or *** symptomatic stones,laparoscopic cholecystectomy has become the therapy of ***-Pugh class and MELD score are the best predictors of outcome after *** with severe liver disease are at highest surgical risk,therefore gallstone complications should be treated using noninvasive or minimally invasive procedures,until stabilization of the patient condition.

关键词： Liver cirrhosis Pigment gallstones Cholesterol gallstones Lithogenesis Risk factors Asymptomatic gallstones Laparoscopic cholecystectomy