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Effect of caffeine in the intraventricular hemorrhage of the preterm newborn

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Neural Regeneration Research 2023年第9期18卷 1942-1943页

作者： Pilar Alves-Martinez monica Garcia-Alloza Division of Physiology School of MedicineUniversidad de CadizCadizSpain Biomedical Research and Innovation Institute of Cádiz(INiBICA)Research Unit Puerta del Mar University Hospital University of CadizCadizSpain

There are around 15 million preterm newborns(PT) eve ry year(Atienza-Navarro et al., 2020).With these figures in mind,prematurity represents a major health problem worldwide and it is a leading cause of infant mortality,accounting for up to 35%of all deaths among newborns(Atienza-Navarro et al.,2020) and up to 18% of the deaths among children under 5 years of age.

关键词： newborn infant deaths

FIXED POINT RESULTS ON METRIC-TYPE SPACES

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Acta Mathematica Scientia 2014年第4期34卷 1237-1253页

作者： monica COSENTINO Peyman SALIMI Pasquale VETRO Dipartimento di Matematica e Informatica Universita degli Studi di PalermoVia Archirafi3490123 PalermoItaly Young Researchers and Elite Club Rasht BranchIslamic Azad UniversityRashtIran

In this paper we obtain fixed point and common fixed point theorems for self- mappings defined on a metric-type space, an ordered metric-type space or a normal cone metric space. Moreover, some examples and an applica... 详细信息

关键词： metric-type space fixed point common fixed point Suzuki type mappings cone metric space integral equation

Empagliflozin reduces brain pathology in Alzheimer's disease and type 2 diabetes

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Neural Regeneration Research 2024年第6期19卷 1189-1190页

作者： Carmen Hierro-Bujalance monica Garcia-Alloza Division of Physiology School of MedicineUniversidad de CadizCadizSpain Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz(INIBICA) CadizSpain Salus Infirmorum-Universidad de Cadiz CadizSpain

Alzheimer's disease(AD)and type 2 diabetes(T2D):More than 55 million people suffer from dementia,and it is expected that over 150 million people will suffer from this disease by *** is the most common type of dementia and while aging remains the main risk factor to suffer it,previous studies have also shown that metabolic disorders,and T2D specifically,are also major contributors(Wang et al.,2012).

关键词： Alzheimer diabetes

Optimal dual antiplatelet therapy strategy in elderly patients with acute coronary syndrome

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Journal of Geriatric Cardiology 2021年第3期18卷 210-218页

作者： monica Verdoia Rocco Gioscia Giuseppe De Luca Cardiologia e UnitàCoronarica Ospedale degli InfermiASL BiellaItaly/Division of CardiologyAzienda Ospedaliera-Universitaria“Maggiore della Carità”Universitàdel Piemonte OrientaleNovaraItaly

One out of three hospitalizations for acute coronary syndrome(ACS)involve nowadays elderly patients,carrying together a significant burden of comorbidities and a higher risk of *** particular,both ischemic and haemorrhagic risk are markedly enhanced in advanced age,and strictly interconnected,challenging the management of dual antiplatelet therapy(DAPT)in these *** recent development of several therapeutic options in terms of duration and combination of antiplatelet agents have offered a wider spectrum of opportunities for a more individualized approach in the management of DAPT after an ACS,although the criteria for the selection of the most appropriate strategy in each patient still lack *** particular,dose-adjustment,early aspirin discontinuation,laboratory-driven tailoring and shorter or extended DAPT have been addressed with promising safety and efficacy *** present review provides an updated overview on the emerging evidencefrom randomized clinical trials and subanalyses dedicated to the management of DAPT in elderly patients presenting with ACS.

关键词： patients coronary markedly

The role of the Frontiers of Knowledge Awards in identifying the global leaders in ecological research

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Ecosystem Health and Sustainability 2017年第5期3卷 24-28页

作者： Pablo Jauregui monica Salomone Communications Department BBVA FoundationMadridSpain

Introduction:This paper outlines the origins and rationale of the Frontiers of Knowledge Awards,a new family of international prizes created in 2008 by the BBVA Foundation of *** aim of these awards is to recognize world-class contributions in a range of scientific,technological,and artistic areas which address the central challenges of the twenty-first *** key distinguishing feature is the fact that they have incorporated amongst their categories the two fundamental fields of contemporary environmental research:Ecology and Conservation Biology and Climate ***:By documenting the winners of the Frontiers of Knowledge Awards in these two areas,as well as the reasons for which they received this recognition during their previous nine editions,we show how these prizes have helped to identify some of the leading international figures in environmental science,such as Edward ***,Daniel ***,Jane Lubchenco,and Ilkka ***:In conclusion,we suggest that this initiative contributes to the public salience of the global ecological problems which threaten the future of our *** the same time,the Frontiers of Knowledge Awards serve to highlight the fundamental importance of the pioneering scientists whose research can provide the only reliable basis on which globalpolicy makers must make informed decisions to successfully confront the environmental challenges of our time.

关键词： Ecology conservation biology climate change Awards

Liquid biopsy and blood-based minimal residual disease evaluation in multiple myeloma

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Oncology Research 2023年第3期31卷 271-274页

作者： ALESSANDRO GOZZETTI monica BOCCHIA Division of Hematology University of SienaAzienda Ospedaliera UniversitariaSiena53100Italy

Novel drug availability has increased the depth of response and revolutionised the outcomes of multiple myeloma *** residual disease evaluation is a surrogate for progression-free survival and overall survival and has become widely used not-only in clinical trials but also in daily patient *** marrow aspiration is the gold standard for response evaluation,but due to the patchy nature of myeloma,false negatives are *** biopsy and blood-based minimal residual disease evaluation consider circulating plasma cells,mass spectrometry or circulating tumour *** approach is less invasive,can provide a more comprehensive picture of the disease and could become the future of response evaluation in multiple myeloma patients.

关键词： Myeloma Liquid biopsy Minimal residual disease

Noninvasive assessment of alcoholic liver disease using unidimensional transient elastography(Fibroscan~)

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World Journal of Gastroenterology 2015年第42期21卷 11914-11923页

作者： monica Lupsor-Platon Radu Badea Department of Medical Imaging Regional Institute of Gastroenterology and Hepatology Prof. Dr. Octavian Fodor Iuliu Hatieganu University of Medicine and Pharmacy

Unidimensional transient elastography(TE) is a noninvasive technique, which has been increasingly used in the assessment of diffuse liver diseases. This paper focuses on reviewing the existing data on the use of TE in the diagnosis of fibrosis and in monitoring disease progression in alcoholic liver disease, on the factors that may influence the result of fibrosis prediction, and last but not least, on its potential use in assessing the steatosis degree. Therefore, this field is far from being exhausted and deserves more attention. Further studies are required, on large groups of biopsied patients, in order to find answers to all the remaining questions in this field.

关键词： Transient elastography Alcoholic liver disease Fib

Overview of the phytomedicine approaches against Helicobacter pylori

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World Journal of Gastroenterology 2014年第19期20卷 5594-5609页

作者： Filipa F Vale monica Oleastro Centro de Patogenese Molecular Unidade dos Retrovirus e Infeccoes AssociadasInstituto de Medicina Molecular e Instituto de Investigacao do Medicamento (iMed.ULisboa)Faculdade de FarmaciaUniversidade de LisboaLisboaPortugal Departamento de Doencas Infeciosas Instituto Nacional Saude Dr.Ricardo Jorge1649-016 LisboaPortugal

Helicobacter pylori(***)successfully colonizes thehuman stomach of the majority of the human *** infection always causes chronic gastritis,butmay evolve to serious outcomes,such as peptic ulcer,gastric carcinoma or mucosa-associated lymphoid tis-sue *** first line therapy recommend-ed by the Maastricht-4 Consensus Report comprises theuse of two antibiotics and a proton-pomp inhibitor,butin some regions failure associated with this treatmentis already undesirable ***,treatment failure isone of the major problems associated with *** in-fection and is mainly associated with bacterial *** order to counteract this situation,someeffort has been allocated during the last years in theinvestigation of therapeutic alternatives beyond *** include vaccines,probiotics,photodynamic inactivation and phage therapy,which are briefly revis-ited in this review.A particular focus on phytomedicine,also described as herbal therapy and botanical therapy,which consists in the use of plant extracts for medicinal purposes,is specifically addressed,namely considering its history,category of performed studies,tested com-pounds,active principle and mode of *** herbs already experienced are highly diverse and usually selected from products with a long history of employ-ment against diseases associated with *** infec-tion from each country own folk *** studies demonstrated that many phytomedicine products have an *** activity and gastroprotective ***-though the mechanism of action is far from being com-pletely understood,current knowledge correlates the beneficial action of herbs with inhibition of essential *** enzymes,modulation of the host immune system and with attenuation of inflammation.

关键词： Helicobacter pylori Alternative treatment Phytomedicine Herbal medicine Phytotherapy Botanical therapy Herb medicine Probiotics Antibiotic resistance

ADAPTIVE BUILDING AND SKIN:AN INNOVATIVE COMPUTATIONAL WORKFLOW TO DESIGN ENERGY EFFICIENT BUILDINGS IN DIFFERENT CLIMATE ZONES

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Journal of Green Building 2019年第4期14卷 3-15页

作者： monica Rossi-Schwarzenbeck Angelo Figliola HTWK Leipzig Leipzig University of Applied SciencesGermany Universitàdegli Studi di Roma“La Sapienza ”Italy

This research aims at developing an innovative methodology and the related computational workflow to design energy efficient buildings equipped with climate responsive building skins able to respond dynamically to environmental conditions changing over the *** methodology,called Adaptive Building and Skin(AB&S),is applicable in different climate zones and consists of a computational form-finding method,which supports architects and engineers in the buildings’design process resulting in buildings with optimized energy performance and a high level of indoor and outdoor comfort under changing environmental *** innovativeness of AB&S lies in the fact that it includes the entire design process and considers several internal and external inputs to find the best solutions at all scales of a project:starting from the micro urban-scale with the design of the site and of the building shape,down to the building-scale and finally the *** and functionality of AB&S has been tested and improved in the design of office buildings located in specific cities located in different climate zones(cold,temperate,tropical and subtropical).Results of the application in Berlin,Germany,are presented in detail in this paper.

关键词： adaptive building and skin performance-based form-finding data-driven approach parametric design indoor and outdoor comfort different climate zones