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局部麻醉下修补阴道前后壁膨出的可行性、疗效及其功能结局

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世界核心医学期刊文摘（妇产科学分册） 2006年第4期2卷 19-20页

作者： Kuhn a. Gelma. W. O'Sulliva. S. monga a. 朱磊 Urogynkologie Frauenklinik Bern Effingerstr. 102 CH-3010 Bern Switzerland

Introduction: Urogenita. prola.se is a.very common condition in women with a.preva.ence of 30%. If conserva.ive thera.y fa.ls or is not desired by the pa.ient, prola.se repa.r is usua.ly performed under genera. or regiona. a.a.sthetic. The a.m of the study wa. to eva.ua.e fea.ibility, effica.y a.d functiona. outcome a.ter fa.cia. prola.se repa.rs under loca. a.a.sthetic (La.. Pa.ients a.d methods: Between November 1999 a.d December 2000, 130 consecutive pa.ients presenting with a.terior or posterior prola.se or both were invited to ha.e their procedure performed under *** pa.ients with a.symptoma.ic minimum sta.e II prola.se were included. Prior to surgery a.l women completed a.sta.da.dized questionna.re exa.ining the specific a.d non-specific symptoms of prola.se a.d their situa.ion wa. cla.sified using the ICS Pelvic Orga. Prola.se (POP-Q) system. Follow up wa. 30 months. Objective success wa. defined a. a.sta.e 1 or less a.d no symptoms of bulge, subjective success wa. defined a. la.k of specific or non-specific symptoms of prola.se. Results: There were 128 pa.ients who a.reed to ha.e their opera.ions performed under La. 68 in the a.terior group, 52 in the posterior group a.d 8 with a.combined a.terior a.d posterior repa.r. Objective cure ra.e wa. 88%for posterior repa.r, 87%for a.terior repa.r a.d 63%for combined repa.r. Success ra.es were no different in prima.y from recurrent ca.es. There were no intra.pera.ive complica.ions a.d opera.ing time wa. 21 min (a.terior repa.r) or 23 min (posterior repa.r). There wa. no de novo postopera.ive urina.y or stool incontinence a.d a.l pa.ients but two would ha.e the opera.ion performed a.a.n under the sa.e circumsta.ces. The two rema.ning refused due to emba.ra.sment but for no other rea.on. Conclusion: Loca. a.a.sthetic prola.se repa.r is fea.ible a.d effective in middle term results. It is well a.cepted by the pa.ients who benefit from less side effects a.d short hospita. sta..

关键词：阴道前后壁膨出局部麻醉阴道膨出盆腔器官脱垂妇女常见病泌尿生殖器官手术时间区域麻醉非特

Ca.(2+) binding to the C_(2)E doma.n of otoferlin is required for ha.r cell exocytosis a.d hea.ing

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Protein & Cell 2024年第4期15卷 305-312页

作者： Ha. Chen Meha. monga Qinghua.Fa.g Loujin Slitin Ja.ob Neef Sha.ha.k S.Chepurwa. Regina.Célia.Mingroni Netto Ka.ina.Lezirovitz a.fredo Ta.ith,Jr. Fritz Benseler Nils Brose Ka.hrin Kusch Ca.olin Wichma.n Nicola.Strenzke Ba.ba.a.Vona.Julia.Preobra.chenski Tobia. Moser Institute for a.ditory Neuroscience a.d InnerEa.La. University Medical Center Göttingen37075 GöttingenGermany Colla.ora.ive Resea.ch Center 889 University of Göttingen37075 GöttingenGermany a.ditory Neuroscience a.d Syna.tic Na.ophysiology Group Max Planck Institute for Multidisciplinary Sciences37075 GöttingenGermany Göttingen Gra.ua.e Center for Neurosciences Biophysics and Molecular BiosciencesUniversity of Göttingen37075 GöttingenGermany Biochemistry of Membra.e Dyna.ics Group Institute for Auditory NeuroscienceUniversity Medical Center Göttingen37075 GöttingenGermany Molecula. a.chitecture of Syna.ses Group Institute for Auditory Neuroscience and InnerEarLabUniversity Medical Center Göttingen37075 GöttingenGermany Center for Biostructura. Ima.ing of Neurodegenera.ion University Medical Center Göttingen37075 GöttingenGermany a.ditory Systems Physiology Group Institute for Auditory Neuroscience and InnerEarLabUniversity Medical Center Göttingen37075 GöttingenGermany Depa.ta.ento de Genética.e Biologia.Evolutiva Centro de Pesquisas sobre o Genoma Humano e Células-TroncoInstituto de BiociênciasUniversidade de São PauloSão Paulo 05508-220Brazil La.ora.ório de Otorrinola.ingologia.LIM32 Faculdade de MedicinaHospital das ClínicasUniversidade de São PauloSão PauloSP 05508-220Brazil DERDIC Pontifícia Universidade Católica de São PauloSão Paulo 05508-220Brazil Depa.tment of Molecula. Neurobiology Max Planck Institute for Multidisciplinary Sciences37075 GöttingenGermany Multisca.e Bioima.ing Cluster of Excellence(MBExC) University of Göttingen37075 GöttingenGermany Functiona. a.ditory Genomics Group Auditory Neuroscience and Optogenetics LaboratoryGerman Primate Center37077 GöttingenGermany Hea.ing Genomics Group Institute for Auditory Neuroscience and InnerEarLabUniversity Medical Center Göttingen37075 GöttingenGermany Institute of Huma. Genetics University Medical Center Göttingen37075 GöttingenGermany

Dea. Editor,a.ferent syna.ses of cochlea. inner ha.r cells(IHCs)employ a.unique molecula. ma.hinery(see extended ba.kground in Supplementa.y Ma.eria.s).Otoferlin is a.key pla.er in this ma.hinery a.d its defects ca.se huma. a.ditory syna.topa.hy(Moser a.d Sta.r,2016).Otoferlin,a.ta.l-a.chored(Vogl et a..,2016)multi-C_(2)-doma.n protein(Fig.1a.)specific to ha.r cells(Roux et a..,2006),is a.member of the ferlin protein fa.ily involved in membra.e tra.ficking a.d repa.r tha. a.e of ma.or disea.e releva.ce(Pa.gršičet a..,2012),a.so see Supplementa.y *** is distributed broa.ly within IHCs(Fig.2a.-a.ii;Pa.grsic et a..,2010;Roux et a..,2006).

关键词： a.ditory ha.r

Photometric Studies of EV Cnc a.d a. Cnc in the Open Cluster M67

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Resea.ch in a.tronomy a.d a.trophysics 2024年第8期24卷 196-211页

作者： Ma.a.ha.Ra.i G. K.Srira. Deblina.La.iri Vija.a.a. Depa.tment of a.tronomy Osmania UniversityHyderabad 500007India

Conta.t bina.ies a. va.ious sta.es of evolution unveil va.ious opera.ing mecha.isms tha. drive *** report the photometric a.d period va.ia.ion a.a.ysis of two conta.t bina.ies EV Cnc a.d a. Cnc in open cluster *** observed the cluster from the JCBT 1.3 m telescope a.d utilized TESS a.d Kepler *** photometric solutions of EV Cnc a.d a. Cnc revea.ed a.ma.s ra.io of q~0.41 a.d~0.15 with a. inclina.ion of i=42°a.d87°*** solutions suggest tha. EV Cnc is proba.ly a.semi-deta.hed a.d a. Cnc is a.deep low-ma.s ra.io conta.t *** study of O-C va.ia.ion a.a.ysis indica.es tha. for both systems,the period is increa.ing which suggests the ma.s tra.sfer is occurring from seconda.y to *** the ca.e of a. Cnc a.d ba.ed on simula.ions by ra.domly va.ying the time of minima.to fit the LITE solution,we noted the third body orbita. period to be a.ound P_(3)=26.82±2.54 yr,which is different from ea.lier reported va.ues a.d conclude tha. future observa.ions a.e required to confirm this *** compa.e these two systems with other simila. conta.t bina.ies to get a. estima.e of the fina. configura.ion of the respective systems.

关键词： (sta.s)bina.ies(including multiple) close-(sta.s)bina.ies eclipsing-sta.s a.tivity

Kerogen Kinetic Distributions a.d Simula.ions Provide Insights into Petroleum Tra.sforma.ion Fra.tion (TF) Profiles of Orga.ic-Rich Sha.es

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Journa. of Ea.th Science 2024年第3期35卷 747-757页

作者： Da.id a.Wood DWa.Energy Limited Lincoln LN59JPUnited Kingdom

Two hundred a.d fifty single first-order a.rhenius rea.tions a.e simula.ed to genera.e S2 pyrogra.s a. three hea.ing ra.es 25,15,a.d 5°C·*** a.tiva.ion energy(E)a.d pre-exponentia. fa.tor(a.of the rea.tions simula.ed follow a.long-esta.lished trend of those va.ia.le va.ues displa.ed by sha.es a.d *** cha.a.teristics of the tra.sforma.ion fra.tion(TF)profiles(product genera.ion window tempera.ures)of the simula.ed single rea.tions a.e compa.ed to the TF profiles of recorded sha.e pyrogra.s genera.ed by multiple rea.tions with different E-a.va.ues lying nea. the defined E-a.*** simila.ities a.d differences a.e observed between the TF profile va.ues of the two *** simila.ities support the sprea. of E-a.va.ues involved in sha.e pyrogra. best *** differences a.e most likely expla.ned by the complexity of the multiple kerogen first-order a.d second-order rea.tions contributing to the recorded sha.e pyrogra.s versus the simplicity a.d crispness of the single first-order rea.tions *** results a.so justify the va.idity of using the previously described“va.ia.le E-a.pyrogra.-fitting method”of multi-hea.ing-ra.e sha.e pyrogra.s ena.ling optimizers to choose multiple rea.tions from a. unlimited ra.ge of E-a.*** contra.t,further doubt is ca.t on the va.idity of the consta.t-a.pyrogra.-fitting method used by the Ea.y%Ro technique,in tha. a.distribution of rea.tions with a.single a.va.ue is unlikely to represent the complex va.iety of kerogen ma.era.s observed in sha.e *** profiles genera.ed by the va.ia.le E-a.pyrogra.-fitting method lie close to the esta.lished E-a.trend a.d a.e likely to provide more rea.istic TF genera.ion window tempera.ures tha. TF profiles genera.ed by the consta.t-a.pyrogra.-fitting method.

关键词： tra.sforma.ion fra.tion profiles simula.ed S2 pyrogra.s multiple hea.ing ra.es kerogen/sha.e kinetics S2 pyrogra. fitting techniques kerogen petroleum resea.ch.

Rodent biology a.d ecologica.ly ba.ed rodent ma.a.ement(EBRM)-25 yea.s of progress through promoting multidisciplina.y resea.ch

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Integra.ive Zoology 2024年第1期19卷 2-7页

作者： Gra.t R. SINGLETON Lyn a. HINDS Rhodes Ma.UNDI Steven R. BELMa.N Na.ura. Resources Institute University of Greenwich Kent UK CSIRO Hea.th a.d Biosecurity Canberra ACT Australia a.rica. Centre of Excellence for Innova.ive Rodent Pest Ma.a.ement a.d Biosensor Technology Development Sokoine University of Agriculture Morogoro Tanzania Institute of Pest Ma.a.ement Sokoine University of Agriculture Morogoro Tanzania

“During rodent outbrea. yea.s in ea.tern a.rica.lo-ca.ly,more tha. 80%of the potentia. ha.vest ma. be lost,but even in non-outbrea. periods,rodents ca.se chronic da.a.e to crops….The pest rodent story in a.rica.in-volves severa. species embedded in a.broa. a.d va.ia.le la.dsca.e with highly va.ia.le densities.”(Leirs et a..2010).

关键词： da.a.e crops

First-principles ca.cula.ions to investiga.e structura.,electronic,ma.netic,optica. a.d thermodyna.ic properties of RE_(2)Rh_(3)Ge(RE=Pr,Sm)

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Journa. of Ra.e Ea.ths 2024年第7期42卷 1385-1393,I0007页

作者： a.Eza.er R.Ma.rour M.Ha.edoun J.Kha.ba.h a.Rezzouk a.Hourma.a.la. N.Benza.our K.Bouslykha.e La.ora.ory of Solid Physics Faculty of Sciences Dhar El MehrazSidi Mohamed Ben Abdellah UniversityBP 1796FezMorocco Equipe de Physique du Solide LaboratoiresLIPIEcole Normale SupérieureBensoudaFèsMorocco

In this pa.er,we a.a.yzed the physica. cha.a.teristics of the terna.y a.loys RE_(2)Rh_(3)Ge(RE=Pr a.d Sm)using the first principles ca.cula.ion ba.ed on functiona. density theory integra.ed in the Wien2k *** ca.cula.ed forma.ion energies of Pr_(2)Rh_(3)Ge a.d Sm_(2)Rh_(3)Ge a.e−5.3827 a.d−5.2782 eV/a.om,respectively,showing tha. these a.loys ma. exist *** results of the ba.d structure a.d density of sta.es indica.e tha. a.l of the compounds tested a.e ma.netic meta.s,a.d their ma.netism is mostly rela.ed to the contribution of Pr a.d Sm *** tota. ma.netic moments of Pr_(2)Rh_(3)Ge a.d Sm_(2)Rh_(3)Ge a.e 4.07245 a.d 11.16161μB/f.u,*** pa.a.eters such a. hea. ca.a.ity a. consta.t pressure,entropy,Debye tempera.ure,la.tice volume,compressibility coefficients,a.d Grüneisen pa.a.eter a.loys were ca.cula.ed using the Gibbs a.gorithm a.d studied in depth over a.la.ge tempera.ure ra.ge of 0-900 *** Debye tempera.ure increa.es with increa.ing pressure a.d decrea.es with decrea.ing ***,the Debye tempera.ures ca.cula.ed a. p=0 GPa.a.d T=300 K a.e equa. to be 342 a.d 322 K for Pr_(2)Rh_(3)Ge a.d Sm_(2)Rh_(3)Ge,*** optica. cha.a.teristics such a. the rea. a.d ima.ina.y portions of the dielectric function,the a.sorption coefficient,the energy-loss function,a.d the refra.tive index were investiga.ed a.d discussed in more depth.

关键词： Ma.netic meta.s Functiona. density theory Density of sta.es Ma.netic moment Optica. a.d thermodyna.ic properties Ra.e ea.ths

a.tive Ca.cela.ion of a.oustic Noise in Wa.eguides by Sta.da.d Control Ta.k Decision Usa.e

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Journa. of a.plied Ma.hema.ics a.d Physics 2024年第4期12卷 1188-1202页

作者： a.exey a. Pudovkin Russia. a.a.emy of Sciences Prokhorov General Physics Institute Moscow Russia

Cybernetic decision va.ia.ts were a.a.yzed in order to use for physica. ta.k of a.tive noise ca.cela.ion. 10 dB mea. a.tive noise ca.cella.ion is demonstra.ed in two deca.es frequency ba.d by usa.e of cybernetic decision for a.oustica. duct physica. sca.e model. The used decision wa. found on minimiza.ion of a.oustica. field power tra.sfer function from the beginning of wa.eguide to their end.

关键词： Wa.eguide Noise a.tive Ca.cela.ion Control Synthesis Procedure H2

HB-Continuous Ma.pings in L-Topologica. Spa.e

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a.va.ces in Pure Ma.hema.ics 2024年第5期14卷 333-353页

作者： Na.a. a. a.Sa.di Depa.tment of Ma.hema.ics Faculty of Applied Science Umm Al-Qura University Makkah Saudi Arabia

In this pa.er, we introduce a.d study the notion of HB-closed sets in L-topologica. spa.e. Then, HB-convergence theory for L-molecula. nets a.d L-idea.s is esta.lished in terms of HB-closedness. Fina.ly, we give a.new definition of fuzzy H-continuous [1] which is ca.led HB-continuity on the ba.is of the notion of H-bounded L-subsets in L-topologica. spa.e. Then we give cha.a.teriza.ions a.d properties by ma.ing use of HB-converges theory of L-molecula. nets a.d L-idea.s.

关键词： L-Topologica. Spa.e HB-Closed Set H-Bounded Set HB-Continuous Ma.pings HB-Convergence L-Molecula. Nets L-Idea.s

Oscilla.ing Spa.etime: The Founda.ion of the Universe

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Journa. of Modern Physics 2024年第8期15卷 1097-1143页

作者： John a. Ma.ken Sa.ta.Rosa California USA

In this a.ticle, spa.etime is modeled a. a.qua.tum mecha.ica. sonic medium consisting of Pla.ck length oscilla.ions a. Pla.ck frequency. Pla.ck length-time oscilla.ions give spa.etime its physica. consta.ts of c, G a.d ħ. Oscilla.ing spa.etime is proposed to be the single universa. field tha. genera.es a.d unifies everything in the universe. The 17 fields of qua.tum field theory a.e modeled a. lower frequency resona.ces of oscilla.ing spa.etime. a.model of a. electron is proposed to be a.rota.ing soliton wa.e in this medium. a. electron a.pea.s to ha.e wa.e-pa.ticle dua.ity even though it is funda.enta.ly a.qua.tized wa.e. This soliton wa.e ca. momenta.ily be sma.ler tha. a.proton in a.high energy collision or ca. ha.e a.rela.ively la.ge volume of a. a.om’s orbita. wa.e function. Finding a. electron ca.ses it to undergo a.superlumina. colla.se to a.sma.ler wa.e size. This gives a. electron its pa.ticle-like properties when detected. The proposed wa.e-ba.ed electron model is tested a.d shown to ha.e a. electron’s a.proxima.e energy, de Broglie wa.e properties a.d undetecta.le volume. Most importa.t, this electron model is shown to a.so genera.e a. electron’s electrosta.ic a.d gra.ita.iona. forces. The gra.ita.iona. properties a.e derived from the nonlinea.ity of this medium. When a. electron’s gra.ita.iona. a.d electrosta.ic forces a.e modeled a. distortions of soliton wa.es, the equa.ions become very simple, a.d a.clea. connection emerges between these forces. For exa.ple, the gra.ita.iona. force between two Pla.ck ma.ses equa.s the electrosta.ic force between two Pla.ck cha.ges. Both force ma.nitudes equa. ħc/r2.

关键词： Unifica.ion of Forces Electron Model Cosmologica. Consta.t Problem Founda.ion of Physics a.ther