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Acceptance and experience of HIV-Infected Adolescents in two Hospitals in Yaoundé

Open Journal of Pediatrics 2024年第2期14卷 435-443页

作者： Isabelle Mekone Nkwele ne.ly Kamgaing Pierrette Amanda emah Manga Jeannette Épée Ngoué Hélène Kamo Sélangai Claude Audrey Meguieze Nsoh Ndeh-Fofang Serge tchoukoua Jean-Baptiste Fotso Djemo Paul Koki Ndombo Department of Pediatrics Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Institut Supérieur des Sciences de la Santé de Bangangté Université des Montagnes Bangangté Cameroon Faculty of Medicine and Biomedical Sciences University of Garoua Garoua Cameroon

Introduction: Access to antiretroviral drugs has improved the survival of children infected with the Human Immunodeficiency Virus (HIV). As they reach adolescence, they are confronted with various constraints related to the infection and its treatment, in addition to those of the growth period they are going through. the main aim of the study was to assess the acceptance and describe the experience of HIV infection by infected adolescents but also to investigate the factors associated with good acceptance and a positive experience. Methodology: the cross-sectional analytic study concerned HIV-infected adolescents aged 15 to 19 followed up at the Chantal Biya Foundation-Mother and Child Centre (CMe-FCB) and the Yaoundé University Hospital Centre (CHUY) between February 2020 and June 2020. the study saw participants complete a questionnaire containing socio-demographic data and assessing acceptance and experience with the infection. Data analysis was accomplished using epi info software version 7.***.2.6. Results: One hundred and thirteen HIV-infected adolescents were included in the study. the sex ratio was 0.68 and the mean age was 17 years. More than half of the adolescents had a good acceptance and positive experience with the infection. Related factors were the adolescent’s perception of good health and participation in an association with other infected adolescents. Conclusion: emphasizing the psychological and educational follow-up of infected adolescents and encouraging their participation in associations for adolescents living with HIV could reduce the consequences of poor acceptance and ensure a better transition to adulthood. .

关键词： HIV Adolescent Acceptance experience

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Quality evaluation of Nothofagus pumilio seeds linked to forest management and climatic events

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ecological Processes 2024年第1期13卷 98-107页

作者： Julian Rodríguez-Souilla Jimena e.Chaves María Vanessa lencinas Juan Manuel Cellini Fidel A.Roig Pablo l.Peri Guillermo Martinez Pastur laboratorio de Recursos Agroforestales Centro Austral de Investigaciones Científicas (CADIC) Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET ) laboratorio de Investigaciones en Maderas (lIMAD) Universidad Nacional de la Plata (UNLP) Instituto Argentino de Nivología Glaciología y Ciencias Ambientales (IAN-IGLA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Instituto Nacional de tecnología Agropecuaria (INtA) Universidad Nacional de la Patagonia Austral (UNPA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET )

Background Forest ecosystems undergo significant transformations due to harvesting and climate fluctuations, emphasizing the critical role of seeding in natural regeneration and long-term structural preservation. Climate change further amplifies these dynamics, affecting phenology across species and regions. In tierra del Fuego(Argentina), Nothofagus pumilio(lenga) forests represent the most important timber resource, and it is managed through different silvicultural strategies. this species demonstrates notable post-disturbance regeneration, yet seed fall exhibits signifi-cant variability, leading to variations in seed quality(e.g., viability). this study aims to assess fluctuations in N. pumilio seed quality, determine how it varies concerning forest management strategies, annual productivity, and the co-occurrence of climatic phenomena including el Ni?o-Southern Oscillation(eNSO) and the Southern Annular Mode(SAM).Results Viable seeds represented 18.4% of the total, notably higher in unharvested than in managed areas. Con-versely, empty seeds were more prevalent in harvested areas(> 75%). Seed quality exhibited significant differences across silvicultural treatments, except for insect-predated seeds, which had similar proportions across all areas, though dispersed retention showed higher predation. When considering years with varying production levels, high-production years favoured full and viable seeds, particularly in unharvested forests and aggregated retention, while low-production years saw reduced viability across all treatments. Quadratic models revealed that viability increased with seed production, where unharvested forests achieved the highest values. Climate variability influenced seed proportions, where eNSO+/SAM+ promoting more full and viable seeds, while eNSO–/SAM+ favoured non-predated seeds, especially in unharvested *** Seed quality varies among treatments and years with different levels of seeding. Variations in seed qual-ity, l

关键词： Forest management Seeding Climate change extreme event Patagonia

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Hydroxyapatite composites with carbon allotropes:Preparation,properties,and applications

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Particuology 2024年第5期88卷 239-265页

作者： Boris I.Kharisov Oxana V.Kharissova lucy t.González Yolanda Peña Méndez Igor e.Uflyand Idalia Gómez de la Fuente Universidad Autónoma de Nuevo león Ave.UniversidadCiudad UniversitariaSan Nicolás de los GarzaNuevo León 66455Mexico tecnologico de Monterrey Escuela de Ingeniería y CienciasMonterreyNuevo Leon 64890Mexico Department of Chemistry Southern Federal UniversityRostov-on-DonRussia

Hydroxyapatite(HA)and its composites with inorganic additives,dopants,and polymers is a rapidly developing branch in the materials *** particular,carbon allotropes are widely used in these composites being widely applied for medical *** a gap of insufficient generalization of recent achievements in the field of the HA/Carbon composites,in this review we present the state of the art of the field of HA composites and hybrids with classic carbon allotropes and *** composites are known for carbon nanotubes,nanofibers,graphene and its oxidized forms,as well as,in a lesser grade,for graphite,fullerenes,nanodiamonds,carbon nanofoams,*** composites can be fabricated by a variety of classic and less-common methods,such as co-precipitation(with or without ultrasonic treatment),CVD,hot isostatic pressing,hydrothermal,spark plasma sintering,biomimetic mineralization,thermal and plasma spray,electrochemical and electrophoretic deposition,self-assembling,3D printing,electrospinning,and lyophilisation,among *** of various synthesis techniques can be also carried out for composite *** or synthetic HA can be used as it is for further interaction with carbon allotropes or it can be first prepared and then reacted with carbon counterpart;similarly,carbon allotropes can be introduced into the interaction with HA directly or they can be first synthesized,in particular from *** biocompatible composites can be produced in the form of coatings,powders,and scaffolds and can additionally contain quantitative amounts of third phases,frequently natural or synthetic *** these composites,especially with O-containing functionalizing groups,HA disadvantages could be considerably decreased with simultaneous enhancement of mechanical properties,becoming similar to human bone,chemical stability and biocompatibility,as well as possessing antibacterial ***→G reduction and higher HA decoration were obs

关键词： Hydroxyapatite Carbon nanotubes Graphene Quantum dots Fullerenes Nanodiamonds

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Multifunctional RGD coated a single-atom iron nanozyme:A highly selective approach to inducing ferroptosis and enhancing immunotherapy for pancreatic cancer

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Nano Research 2024年第6期17卷 5469-5478页

作者： Haoqi Pan Xu Chen Mingming Xiao he Xu Jiansheng Guo Zhiyi lu Dong Cen Xianjun Yu Si Shi Department of Pancreatic Surgery Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China Shanghai Pancreatic Cancer Institute Shanghai 200032China Pancreatic Cancer Institute Fudan UniversityShanghai 200032China Key laboratory of Advanced Fuel Cells and electrolyzers technology of Zhejiang Province Qianwan Institute of CNITECHNingbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201China Department of Pathology of Sir Run Run Shaw Hospital Zhejiang University School of MedicineHangzhou 310016China Key laboratory of laparoscopic technology of Zhejiang Province Department of General SurgerySir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China

Nanozyme is a new promising approach to cancer therapy for its ability to induce ferroptosis by activating H_(2)O_(2)via a traditional radical pathway and enhance cancer ***,short half-life period of hydroxyl radical(·OH)results in unsatisfied ***,we synthesized a single-atom iron nanozyme(Fe-SAzyme),which can activate H_(2)O_(2)via a non-radical pathway to generate Fe-based reactive oxygen species(ROS)(O=FeO_(3)=O)for promoting the ferroptosis of pancreatic cancer *** Fe-SAzyme could be specifically phagocytosed by pancreatic cancer cells,increasing ROS levels and inhibiting glutathione(GSH)synthesis,which activates *** magnetic resonance imaging(MRI)showed decreased t2 signal after intravenous injection of RGD@Fe-AC(AC=activated carbon).Moreover,RGD@Fe-AC promoted dendritic cell(DC)maturation,overcame treg-mediated immunosuppression,activated t cells to trigger adaptive immune responses,and enhanced the efficacy ofα-PD-l1 *** research demonstrated that RGD@Fe-AC provided a straightforward,easily implemented,and selective approach for pancreatic cancer treatment and immunotherapy.

关键词： single-atom iron nanozyme pancreatic cancer immunotherapy ferroptosis

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Self-powered wireless environmental monitoring system for in-service bridges by galloping piezoelectric-triboelectric hybridized energy harvester

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Science China(technological Sciences) 2024年第5期67卷 1498-1509页

作者： HUANG KangXu WANG XiaoFei WANG li ZHOU YuHui lIU FuHai CHANG ShiYuan ZHU Juntao ZHOU YuXuan ZHANG he lUO JiKui College of Civil engineering and Architecture Zhejiang UniversityHangzhou310058China Anhui transport Consulting&Design Institute Co. Ltd.Hefei230088China College of electronics&Information Hangzhou Dianzi UniversityHangzhou310018China Center for Balance Architecture Zhejiang UniversityHangzhou310058China College of Information Science&electronic engineering Zhejiang UniversityHangzhou310027China

the energy harvesting technology for the ubiquitous natural wind enables a desirable solution to the issue of distributed sensors in the bridge environmental sensing Internet of things(Io t)system being restricted to conventional energy *** this work,a self-powered system based on a compact galloping piezoelectric-triboelectric energy harvester(GPteH)is developed to achieve efficient wind energy *** GPteH is constructed on the prototype of a cantilever structure with piezoelectric macro-fiber composite(MFC)sheets and a rectangular bluff body with triboelectric nanogenerators(teNGs).through a special swing-type structural design with iron blocks inside the bluff body,the GPteH exhibits preferable aerodynamic behavior and excellent energy conversion efficiency,compared to conventional cantilever kind of piezoelectric wind energy harvester(PWeH).the GPteH also demonstrates the capability of high output power density(PeH of 23.65 W m^(-2)and teNG of 1.59 W m^(-2)),superior response wind speed(about 0.5 m s^(-1)),and excellent long-term stability(over 14000 cyclic tests).Furthermore,a power management system is developed to efficiently utilize the output energy from GPteH to power the sensors and wirelessly transmit environmental data to the *** proposed GPteH-powered system exhibits a great potential for the bridge environmental monitoring and Io t technologies.

关键词： self-powered hybrid nanogenerator triboelectric nanogenerator macro-fiber composite wireless environmental monitoring system

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Double-confined nanoheterostructure Sb/Sb_(2)S_(3)@ti_(3)C_(2)t_(x)@C toward ultra-stable li-/Na-ion batteries

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Rare Metals 2024年第5期43卷 2067-2079页

作者： Dan Wang Qun Ma Huan he Zhi-Yuan Wang Run-Guo Zheng Hong-Yu Sun Yan-Guo liu Chun-li liu School of Materials Science and engineering Northeastern UniversityShenyang110819China School of Resources and Materials Northeastern University at QinhuangdaoQinhuangdao 066004China Key laboratory of Dielectric and electrolyte Functional Material hebei Province Qinhuangdao 066004China Department of Physics and Oxide Research Center Hankuk University of Foreign StudiesYongin 17035Korea

Antimony-based materials with high capacities and moderate potentials are promising anodes for lithium-/-sodium-ion ***,their tremendous volume expansion and inferior conductivity lead to poor structural stability and sluggish reaction ***,a doubleconfined nanoheterostructure Sb/Sb_(2)S_(3)@ti_(3)C_(2)t_(x)@C has been fabricated through a solvothermal method followed by low-temperature.he.t *** dual protection of“MXene”and“carbon”can better accommodate the volume expansion of Sb/Sb_(2)S_(3).the strong covalent bond(ti-S,ti-O-Sb,C-O-Sb)can firmly integrate Sb-based material with ti_(3)C_(2)t_(x)and carbon,which significantly improves the structure *** addition,the carbon layer can restrain the oxidation of MXenes,and the nano-Sb/Sb_(2)S_(3)can facilitate electron/ion transport and suppress the restacking of *** heterogeneous interface between Sb and Sb_(2)S_(3)can further promote interfacial charge *** MXene-Sb/Sb_(2)S_(3)@C-1 with the optimal Sb content shows high specific capacities,comparable rate properties and ultra-stable cycling performances(250 m Ah·g^(-1)after 2500 cycles at 1 A·g^(-1)for sodium-ion batteries).ex situ X-ray diffractometer(XRD)test reveals the storage mechanism including the conversion and alloying process of MXene-Sb/Sb_(2)S_(3)@*** voltammetry(CV)test results demonstrate that the pseudocapacitance behavior is dominant in MXene-Sb/Sb_(2)S_(3)@C-1,especially at large *** design paves the way for exploring high-performance alloy-based/conversion-type anode for energy storage devices.

关键词： Sb/Sb_(2)S_(3) MXene Carbon Anode lithium-ion batteries Sodium-ion batteries

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Critical considerations for the management of acute abdomen in transplant patients

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World Journal of transplantation 2024年第2期14卷 8-12页

作者： efstathios t Pavlidis Georgios Katsanos Athanasios Kofinas Georgios tsoulfas Ioannis N Galanis theodoros e Pavlidis the 2^(nd)Department of Propaedeutic Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece Department of transplantation Surgery Center for Research and Innovation in Solid Organ TransplantationAristotle University of ThessalonikiSchool of MedicineThessaloniki 54642Greece

the number of solid organ transplantations performed annually is increasing and are increasing in the following order:Kidney,liver,heart,lung,pancreas,small bowel,and uterine ***,the outcomes of transplants are impro-ving(organ survival>90%after the 1st year).therefore,there is a high probability that a general surgeon will be faced with the management of a transplant patient with acute *** problems in immunocompromised patients may not only include graft-related problems but also nongraft-related *** perioperative regulation of immunosuppression,the treatment of accompanying problems of immunosuppression,the administration of cortisol and,above all,the realization of a rapidly deteriorating situation and the accurate evaluation and interpretation of clinical manifestations are particularly important in these *** perioperative assessment and preparation includes evaluation of the patient’s cardiovascular system and determining if the patient has hypertension or suppression of the hypothalamic-pituitary-adrenal axis,or if the patient has had any coagulation mechanism abnormalities or thromboembolic *** in transplant patients is associated with the use of calci-neurin inhibitors,corticosteroids,and antiproliferation *** times,the clinical picture is atypical,resulting in delays in diagnosis and treatment and leading to increased morbidity and *** computed tomo-graphy is of utmost importance for early diagnosis and *** recipients are prone to infections,especially specific infections caused by cytomegalovirus and Clostridium difficile,and they are predisposed to intraop-erative or postoperative complications that require great care and *** is necessary to follow evidence-based therapeutic ***,it is required that the clinician choose the correct therapeutic plan for the patient(conservative,emergency open surgery or minimally invasive s

关键词： Acute abdomen Abdominal emergency surgery transplantation Immunocompromised patients Immuno-suppression Posttransplantation surgery

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next-to-leading-order relativistic and QCD corrections to prompt J/ψpair photoproduction at future e^(+)e^(−)colliders

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Chinese Physics C 2024年第8期48卷 104-112页

作者： Zhi-Guo he Xiao-Bo Jin Bernd A.Kniehl Rong li Department of Physics and electronics School of Mathematics and PhysicsBeijing University of Chemical TechnologyBeijing 100029China II.Institut für theoretische Physik Universität HamburgLuruper Chaussee 14922761 HamburgGermany Institut für theoretische Physik Universität Regensburg93040 RegensburgGermany Center of Advanced Quantum Studies Department of PhysicsBeijing Normal UniversityBeijing 100875China MOe Key laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter School of PhysicsXi’an Jiaotong UniversityXi’an 710049China Institute of theoretical Physics Xi’an Jiaotong UniversityXi’an 710049China

Within the framework of nonrelativistic-QCD factorization,we calculate both the next-to-leading-order relativistic and QCD corrections to prompt J/ψpair production,with feed-down fromψ(2S)mesons,via photon-photon collisions at future e^(+)e^(−)colliders,including the Future Circular lepton Collider(FCC-ee),the Circular electron Positron Collider(CePC),and the Compact linear Collider(ClIC).We present total cross sections and distributions in single J/ψtransverse momentum and rapidity,as well as in J/ψpair invariant *** relativistic and QCD corrections both turn out to be large and ***,the production rates are large enough for useful experimental studies.

关键词： heavy quarkonium perturbative calculation two-photon collisions

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Al-Ca-Fe合金中Al_(10)CaFe_(2)化合物的形成与表征

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transactions of Nonferrous Metals Society of China 2024年第2期34卷 361-377页

作者： N.A.BelOV t.K.AKOPYAN e.A.NAUMOVA V.V.DOROSheNKO t.A.SVIRIDOVA N.O.KOROtKOVA National University of Science and technology MISIS 4 Leninsky pr.Moscow 119049Russia Baikov Institute of Metallurgy and Materials Science 49 Leninsky pr.Moscow 119991Russia

采用热力学计算和实验技术研究铝角的Al-Ca-Fe体系相图,包括液相面投影图和凝固反应。结果表明,与铝固溶体(Al)平衡的不是Al_(3)Fe相,而是一种组成符合化学式Al_(10)CaFe_(2)的三元化合物。通过包晶转变l+Al_(3)Fe→(Al)+Al_(10)CaFe_(2... 详细信息

采用热力学计算和实验技术研究铝角的Al-Ca-Fe体系相图,包括液相面投影图和凝固反应。结果表明,与铝固溶体(Al)平衡的不是Al_(3)Fe相,而是一种组成符合化学式Al_(10)CaFe_(2)的三元化合物。通过包晶转变l+Al_(3)Fe→(Al)+Al_(10)CaFe_(2)(638℃,3.3%Ca和0.5%Fe,摩尔分数)发生从二元化合物到三元化合物的转变。与针状Al_(3)Fe相夹杂物不同,三元化合物的初晶和共晶具有致密的形貌。使用第一性原理计算和X射线衍射分析确定三元化合物Al_(10)CaFe_(2)的晶格结构。此外,近共晶合金Al-6%Ca-1%Fe(质量分数)在500~600℃退火后具有细晶组织,过量相的总体积分数约为25%。因此,Al-Ca-Fe体系可用于制造新的铝基复合合金。

关键词： Al-Ca合金金属间化合物相图相变显微组织铝基复合材料

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27-Hydroxycholesterol/liver X receptor/apolipoprotein e mediates zearalenone-induced intestinal immunosuppression:A key target potentially linking zearalenone and cancer

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Journal of Pharmaceutical Analysis 2024年第3期14卷 371-388页

作者： Haonan Ruan Jing Zhang Yunyun Wang Ying Huang Jiashuo Wu Chunjiao he tongwei Ke Jiaoyang luo Meihua Yang Key laboratory of Bioactive Substances and Resources Utilization of Chinese herbal Medicine Ministry of EducationInstitute of Medicinal Plant DevelopmentChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing100193China

Zearalenone(ZeN)is a mycotoxin that extensively contaminates food and feed,posing a significant threat to public ***,the mechanisms behind ZeN-induced intestinal immunotoxicity remain *** this study,Sprague-Dawley(SD)rats were exposed to ZeN at a dosage of 5 mg/kg/day *** a duration of 14 *** results demonstrated that ZeN exposure led to notable pathological alterations and immunosuppression within the ***,ZeN exposure caused a significant reduction in the levels of apolipoprotein e(Apoe)and liver X receptor(lXR)(Persely,it upregulated the levels of myeloid-derived suppressor cells(MDSCs)markers(Pecreased the presence of 27-hydroxycholesterol(27-HC)in the intestine(Pt was observed that Apoe or lXR agonists were able to mitigate the immunosuppressive effects induced by ***,a bioinformatics analysis highlighted that the downregulation of Apoe might elevate the susceptibility to colorectal,breast,and lung *** findings underscore the crucial role of the 27-HC/lXR/Apoe axis disruption in ZeN-induced MDSCs proliferation and subsequent inhibition of t lymphocyte activation within the rat ***,Apoe may emerge as a pivotal target linking ZeN exposure to cancer development.

关键词： Zearalenone Intestinal immunosuppression Apolipoprotein e Bioinformatics analysis Cancer

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