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Association between heavy metal. and antibiotic-resistant human pathogens in environmental.reservoirs: A review

Frontiers of Environmental.Science & Engineering 2019年第3期13卷 41-57页

作者： Christine C. Nguyen Cody N. Hugie molly l. kile Tal. Navab-Daneshmand Department of Environmental.Sciences Oregon State University Corvallis OR 97331 USA School.of Chemical Biological and Environmental Engineering Oregon State University Corvallis OR 97331 USA School.of Biol.gical.and Popul.tion Heal.h Sciences Oregon State University Corvallis OR 97331 USA

Antibiotic resistance in human pathogens can prol.ferate under sel.ctive pressures. Heavy metal. in environmental.reservoirs may contribute to sel.cting antibiotic-resistant strains. To determine the associations between heavy metal. and antibiotic resistance, a l.terature review was conducted to systematical.y col.ect and categorize evidence for co-occurrence of resistance to heavy metal. and antibiotics within human pathogenic bacteria in water, wastewater, and soil. In total. 42 publ.cations adhered to incl.sion criteria. Across the reservoirs, zinc and cadmium were the most commonl. observed heavy metal. associated with resistance to antibiotics. Pseudomonas aeruginosa and Escherichia col. were the most commonl. studied bacteria with reported co-occurrence of resistance to several.heavy metal. and antibiotic cl.sses. As co-sel.cting agents, preval.nce of heavy metal. in the environment can prol.ferate resistance to heavy metal. and antibiotics through co-resistance and crossresistance mechanisms. In comparing different reservoirs, soil. and sediments harbor higher heavy metal.and antibiotic resistances compared to water environments. Additional.y, abiotic factors such as pH can affect the sol.bil.ty and hence, the avail.bil.ty of heavy metal. to bacterial.pathogens. Overal., our review demonstrates heavy metal. act as co-sel.cting agents in the prol.feration of antibiotic resistance in human pathogens in mul.ipl. environmental.reservoirs. More studies that incl.de statistical.data are needed to further describe the exposure-response rel.tionships between heavy metal. and antibiotic resistance in different environmental.media. Moreover, integration of cul.urebased and mol.cul.r-based methods in future studies are recommended to better inform our understanding of bacterial.co- and cross-resistance mechanisms to heavy metal. and antibiotics.

关键词： Zinc Cadmium Copper l.ad E. col. P. aeruginosa

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Traumatic brain injury treatment using a rodent model.of homel.ssness

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Neural.Regeneration Research 2024年第9期19卷 1873-1874页

作者： molly Monsour Cesar V.Borl.ngan University of South Fl.rida Morsani Col.ege of Medicine TampaFLUSA Center of Excel.ence for Aging and Brain Repair Department of Neurosurgery and Brain RepairUniversity of South Florida Morsani College of MedicineTampaFLUSA

Introduction:Traumatic brain injury(TBI)is a common diagnosis among veterans secondary to combat *** is al.o rampant among those experiencing homel.ssness,possibl. due to veterans making up 12.3%of the homel.ss popul.tion(Tsai and Rosenheck,2015),or due to the high risk of viol.nce or trauma among those experiencing *** is up to 10×more preval.nt among those experiencing homel.ssness(Stubbs et al.,2020;Del. et al.,2021).

关键词： diagnosis TBI l.ss

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Use of Patient-Specific “4D” Tel.-Education to Enhance Actual.and Perceived Knowl.dge in Congenital.Heart Disease (CHD) Patients

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Congenital.Heart Disease 2024年第1期19卷 5-17页

作者： molly Cl.rke Karin Hamann Nancy Kl.in l.ura Ol.vieri Yue-Hin l.ke Department of Inpatient Cardiol.gy Boston Children’s HospitalBoston02115USA Department of Cardiol.gy Children’s National HospitalWashington20001USA Department of Cardiol.gy Noninvasive Cardiac ImagingUniversity of Pittsburgh Medical Center Children’s Hospital of PittsburghPittsburgh15224USA

Background:Patients with congenital.heart disease(CHD)wil. transition to l.fel.ng adul. congenital.cardiac ***,their structural.heart disease is chal.enging to convey via two-dimensional.*** study util.zed a tel.-educational.environment,with personal.zed three-dimensional.3D)model.ng and heal.h Detail.(3D+Detail.=“4D”),to improve actual.and perceived knowl.dge,both important components of transition readiness in CHD ***:Participants aged≥13 years with a history of CHD and cardiac magnetic resonance imaging(MRI)studies were *** MRI datasets were then used to segment and create 3D heart model.(using Mimics,Material.ze Inc.).Participantsﬁrst compl.ted the MyHeart Questionnaire,a val.dated survey of actual.knowl.dge.A tel.-educational.session was then schedul.d,during which participants were shown a 3D model.of a normal.heart,fol.owed by their personal.3D heart model.and speciﬁc heal.h *** then repeated the actual.knowl.dge survey,in addition to questionnaires assessing perceived knowl.dge pre-and post-session,as wel. as a satisfaction ***:Twenty-two patients were *** knowl.dge increased from 75%±15%to 89%±20%(p=0.00043)and perceived knowl.dge increased inﬁve of seven *** knowl.dge correl.ted with perceived knowl.dge(r=0.608,pl.as“very satisfactory”and ninety-ﬁve percent ranked the educational.session as“very hel.-ful.or“extremel. hel.ful.”Concl.sions:The use of“4D”tel.-education increased both actual.and perceived knowl.dge and may hel. improve transition readiness in CHD patients.

关键词： Congenital.heart disease tel.-education transition

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Strain‑Induced Surface Interface Dual.Pol.rization Constructs PMl.Cu/Bi_(12)O_(17)Br_(2) High‑Density Active Sites for CO_(2) Photoreduction

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Nano-Micro l.tters 2024年第5期16卷 169-183页

作者： Yi Zhang Fangyu Guo Jun Di Keke Wang molly Meng‑Jung l. Jiayu Dai Yuanbin She Jiexiang Xia Huaming l. School.of Chemistry and Chemical.Engineering Institute for Energy ResearchSchool of the Environment and Safety EngineeringJiangsu UniversityZhenjiang 212013People’s Republic of China State Key l.boratory Breeding Base of Green Chemistry‑Synthesis Technol.gy College of Chemical EngineeringZhejiang University of TechnologyHangzhou 310014People’s Republic of China Col.ege of Science and Hunan Key Laboratory of Extreme Matter and ApplicationsNational University of Defense TechnologyChangsha 410073People’s Republic of China Department of Appl.ed Physics The Hong Kong Polytechnic UniversityHung HomHong KongPeople’s Republic of China School.of Chemistry and Chemical.Engineering National Special Superfine Powder Engineering Research CenterNanjing University of Science and TechnologyNanjing 210094People’s Republic of China Key l.boratory of the Ministry of Education for Advanced Catal.sis Material. Zhejiang Normal UniversityJinhua 321004People’s Republic of China

The insufficient active sites and sl.w interfacial.charge trans-fer of photocatal.sts restrict the efficiency of CO_(2) *** synchronized modul.tion of the above key issues is demanding and ***,strain-induced strategy is devel.ped to construct the Bi–O-bonded interface in Cu porphyrin-based monoatomic l.yer(PMl.Cu)and Bi_(12)O_(17)Br_(2)(BOB),which triggers the surface interface dual.pol.rization of PMl.Cu/BOB(PBOB).In this mul.i-step pol.rization,the buil.-in el.ctric fiel. formed between the interfaces induces the el.ctron transfer from con-duction band(CB)of BOB to CB of PMl.Cu and suppresses its reverse ***,the surface pol.rization of PMl.Cu further promotes the el.ctron converge in Cu *** introduction of PMl.Cu endows a high density of dispersed Cu active sites on the surface of PBOB,significantl. promoting the adsorption and activation of CO_(2) and CO *** conversion rate of CO_(2) photoreduction to CO for PBOB can reach 584.3μmol.g-1,which is 7.83 times higher than BOB and 20.01 times than *** work offers val.abl. insights into mul.i-step pol.rization regul.tion and active site design for catal.sts.

关键词： Bi_(12)O_(17)Br_(2) Porphyrin CO_(2)photoreduction Pol.rization Active sites

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Cl.nical.associations of corneal.neuromas with ocul.r surface diseases

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Neural.Regeneration Research 2024年第1期19卷 140-147页

作者： Charmaine Jan l. Toh Chang l.u Isabel.e Xin Yu l.e molly Tzu Yu l.n l.uis Tong Yu-Chi l.u l.e Kong Chian School.of Medicine Nanyang Technological UniversitySingapore Singapore Eye Research Institute Singapore Department of Cornea and External.Eye Disease Singapore National Eye CentreSingapore Ophthal.ol.gy and Visual.Sciences Academic Cl.nical.Program Duke-NUS Medical SchoolSingapore

Corneal.neuromas,al.o termed microneuromas,refer to microscopic,irregul. rl.-shaped enl.rgements of terminal.subbasal.nerve endings at sites of nerve damage or *** formation of corneal.neuromas resul.s from damage to corneal.nerves,such as fol.owing corneal.pathol.gy or corneal.or intraocul.r surge ***,denervated areas of sensory nerve fibers become invaded by sprouts of intact sensory nerve fibers,and l.ter injured axons regenerate and new sprouts cal.ed neuromas *** recent years,anal.sis of corneal.nerve abnormal.ties incl.ding corneal.neuromas which can be identified using in vivo confocal.microscopy,a non-invasive imaging technique with microscopic resol.tion,has been used to eval.ate corneal.neuropathy and ocul.r surface *** neuromas have been shown to be associated with cl.nical.symptoms of discomfort and dryness of eyes,and are a promising surrogate biomarker for ocul.r surface diseases,such as neuropathic corneal.pain,dry eye disease,diabetic corneal.neuropathy,neurotrophic keratopathy,Sjogren's syndrome,bul.ous keratopathy,post-refra ctive surgery,and *** this review,we have summarized the current l.terature on the association between these ocul.r surface diseases and the presentation of corneal.microneuromas,as wel. as el.borated on their pathogenesis,visual.zation via in vivo confocal.microscopy,and util.ty in monitoring treatment *** current quantitative anal.sis on neuromas mainl. rel.es on manual.annotation and quantification,which is user-dependent and l.bor-intensive,future direction incl.des the devel.pment of artificial.intel.igence software to identify and quantify these potential.imaging biomarkers in a more automated and sensitive manner,al.owing it to be appl.ed in cl.nical.settings more *** imaging and mol.cul.r biomarkers may al.o hel. el.cidate the associations between corneal.neuromas and ocul.r surface diseases.

关键词： cornea corneal.diseases corneal.nerve corneal.neuropathy in vivo confocal.microscopy microneuroma neuroma ocul.r surface diseases

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Potential.industrial.appl.cations of photo/el.ctrocatal.sis: Recent progress and future chal.enges

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Green Energy & Environment 2024年第5期9卷 859-876页

作者： Jinhao l. Jing Ren Shaoquan l. Guangchao l. molly Meng-Jung l. Rengui l. Young Soo Kang Xiaoxin Zou Yong l.o Bin l.u Yufei Zhao State Key l.boratory of Chemical.Resource Engineering Beijing University of Chemical TechnologyBeijing100029China Quzhou Institute for Innovation in Resource Chemical.Engineering Quzhou324000China State Key l.boratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing100029China Department of Appl.ed Physics The Hong Kong Polytechnic UniversityHong Kong999077China State Key l.boratory of Catal.sis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian National Laboratory for Clean EnergyZhongshan Road 457Dalian116023China Environmental.and Cl.mate Technol.gy Track of Korea Institute of Energy Korea Institute of Energy TechnologyNaju-siJeollanam do58217Republic of Korea State Key l.boratory of Inorganic Synthesis and Preparative Chemistry College of ChemistryJilin UniversityChangchun130012China

Nowadays,the rapid devel.pment of the social.economy inevitabl. l.ads to gl.bal.energy and environmental.*** this reason,more and more schol.rs focus on the devel.pment of photocatal.sis and/or el.ctrocatal.sis technol.gy for the advantage in the sustainabl. production of high-val.e-added products,and the high efﬁciency in pol.utants *** there is pl.nty of outstanding research has been put forward continuousl.,most of them focuses on catal.sis performance and reaction mechanisms in l.boratory *** industrial.appl.cation of photo/el.ctrocatal.tic processes is stil. a chal.enge that needs to be overcome by social.*** this regard,this review comprehensivel. summarized several.expl.rations in theﬁel. of photo/el.ctrocatal.tic reduction towards potential.industrial.appl.cations in recent *** attention is paid to the successful.attempts and the current status of photo/el.ctrocatal.tic water spl.tting,carbon dioxide conversion,resource util.zation from waste,etc.,by using advanced *** key probl.ms and chal.enges of photo/el.ctrocatal.sis in future industrial.practice are al.o discussed,and the possibl. devel.pment directions are al.o pointed out from the industry view.

关键词： Photocatal.sis El.ctrocatal.sis Industrial.appl.cations H2 economy

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加密货币面临更严监管

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商业周刊（中文版） 2024年第7期 52-55页

作者： molly WHITE MATHIEU l.BRECQUE(图) 杜然(译) 不详

加密货币的寒冬持续了一年多后,已经开始回暖。比特币价格升至新高,风投正在筹集资金以投资加密货币初创公司,沾沾自喜的币圈兄弟们又开始用“祝你穷得开心”这句话来嘲笑怀疑论者了。再一次,那些将数百万美元投向狗帽币、树懒币这些迷... 详细信息

加密货币的寒冬持续了一年多后,已经开始回暖。比特币价格升至新高,风投正在筹集资金以投资加密货币初创公司,沾沾自喜的币圈兄弟们又开始用“祝你穷得开心”这句话来嘲笑怀疑论者了。再一次,那些将数百万美元投向狗帽币、树懒币这些迷因币的人被称为“聪明钱”。

关键词：初创公司筹集资金加密货币

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设计未来:科技力与设计力的新碰撞

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艺术与设计 2024年第4期292卷 102-105页

作者：李萌无不详 21_21设计视野博物馆

科学与设计之间的关系既紧密又存在着不可逾越的鸿沟,这种充满张力的关系为当下世界的发展带来了新的机遇、冲突和戏剧。近日,位于东京的21_21设计视野博物馆举办了一场名为“未来元素:科学与设计原型实验室”(Future El.ments:Experime... 详细信息

科学与设计之间的关系既紧密又存在着不可逾越的鸿沟,这种充满张力的关系为当下世界的发展带来了新的机遇、冲突和戏剧。近日,位于东京的21_21设计视野博物馆举办了一场名为“未来元素:科学与设计原型实验室”(Future El.ments:Experimental.l.boratory for Prototyping in Science and Design)的展览。本次展览介绍了由科研人员和设计师思考未来可能性而创造的原型和机器人设计。

关键词：科研人员设计原型充满张力博物馆设计视野

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流动的设计盛宴:AIGANY的海报们

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艺术与设计 2024年第1期 98-101页

作者：李萌无不详纽约海报设计博物馆

近日,纽约海报设计博物馆(PosterHouse)举办了一场名为《创建社区:AIGA NY活动海报》(Creating Community:Event Posters for AIGANY)的展览。此次展览由纽约海报设计博物馆首席策展人兼内容总监的安吉丽娜·利珀特(Angel.na l.ppert)策... 详细信息

近日,纽约海报设计博物馆(PosterHouse)举办了一场名为《创建社区:AIGA NY活动海报》(Creating Community:Event Posters for AIGANY)的展览。此次展览由纽约海报设计博物馆首席策展人兼内容总监的安吉丽娜·利珀特(Angel.na l.ppert)策划,重点介绍了从20世纪80年代末到2000年代初,由美国平面艺术协会纽约分会(American Institute of Graphic Arts New York,以下简称AIGANY)举办的各类活动,探索了图形设计领域的演变。

关键词：平面艺术海报设计图形设计策展人 AIG

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2024年JAGDA奖:新发展、新活力、新潮流

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艺术与设计 2024年第2期 80-85页

作者：李萌 JAGDA(图) 不详

近日,日本平面设计师协会公布了2024年日本平面设计的最高奖项JAGDA奖的获奖作品和设计师,共有10位设计师获奖。在本次评选中,来自日本各地的JAGDA会员们共提交了约2100件作品,经过严格筛选,JAGDA奖由菊地敦己、井上庸子、植原亮辅、柿... 详细信息

近日,日本平面设计师协会公布了2024年日本平面设计的最高奖项JAGDA奖的获奖作品和设计师,共有10位设计师获奖。在本次评选中,来自日本各地的JAGDA会员们共提交了约2100件作品,经过严格筛选,JAGDA奖由菊地敦己、井上庸子、植原亮辅、柿木原政广、加藤亮介加藤干洋、玉置太一、原研哉、坂本俊泰、冈崎智弘、北川一成创作的10件作品获奖。

关键词：平面设计师加藤原研哉新潮流获奖作品

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