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国际原子能机构通报 1995年第1期37卷 37-41页

作者： Ali Boussaha mokdad maksoudi IAEA技术合作计划处非洲科 IAEA技术合作计划处

非洲国家正在通过称作ＡＦＲＡ的区域合作协定努力解决共同的问题。

关键词：非洲核技术国际合作 IAEA

Overall Assessment of Heat Transfer for a Rarefied Flow in a Microchannel with Obstacles Using Lattice Boltzmann Method

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工程与科学中的计算机建模(英文) 2024年第1期138卷 273-299页

作者： Siham Hammid Khatir Naima Omolayo M.Ikumapayi Cheikh Kezrane Abdelkrim Liazid Jihad Asad mokdad Hayawi Rahman Farhan Lafta Rashid Naseer Ali Hussien Younes Menni Laboratory of Development in Mechanics and Materials(LDMM) Zian Achour UniversityDjelfaPB 3117Algeria Department of Technology University Center Salhi Ahmed Naama(Ctr.Univ.Naama)P.O.Box 66Naama45000Algeria Department of Mechanical and Mechatronics Engineering Afe Babalola University Ado Ekiti360101Nigeria Departement of Physics Faculty of ScienceAbou Bekr Belkaid UniversityTlemcen13000Algeria Department of Physics Faculty of Applied SciencesPalestine Technical University-KadoorieTulkarmPalestine Aeronautical Technical Engineering Al-Farahidi UniversityBaghdad10011Iraq Mechanical Engineering Department University of KerbalaKarbala56001Iraq Information and Communication Technology Research Group Scientific Research CenterAl-Ayen UniversityThi-QarIraq National University of Science and Technology Dhi QarIraq

The objective of this investigation is to assess the effect of obstacles on numerical heat transfer and fluid flow momentum in a rectangular microchannel(MC).Two distinct configurations were studied:one without obstacles and the other with alternating obstacles placed on the upper and lower *** research utilized the thermal lattice Boltzmann method(LBM),which solves the energy and momentum equations of fluids with the BGK approximation,implemented in a Python coding *** jump and slip velocity conditions were utilized in the simulation for the MC and extended to all obstacle *** study aims to analyze the rarefaction effect,with Knudsen numbers(Kn)of 0.012,0.02,and *** outcomes indicate that rarefaction has a significant impact on the velocity and temperature *** presence of nine obstacles led to slower fluid movement inside the microchannel MC,resulting in faster cooling at the *** MCs with obstacles,the rarefaction effect plays a crucial role in decreasing the Nusselt number(Nu)and skin friction coefficient(Cf).Furthermore,the study demonstrated that the obstacles played a crucial role in boosting fluid flow and heat transfer in the *** findings suggest that the examined configurations could have potential applications as cooling technologies in micro-electro-mechanical systems and microdevice applications.

关键词： Microfluid rarefied flow LBM microchannel Knudsen number numerical simulation

Expression and role of nuclear receptor coregulators in colorectal cancer

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World Journal of Gastroenterology 2017年第25期23卷 4480-4490页

作者： Mouna Triki Marion Lapierre Vincent Cavailles Raja mokdad-Gargouri IRCM Institut de Recherche en Cancérologie de Montpellier INSERM U1194 Université de Montpellier Institut régional du Cancer de Montpellier Centre de Biotechnologie de Sfax Université de Sfax

Colorectal cancer(CRC) is one of the most common human cancers and the cause of about 700000 deaths per year worldwide. Deregulation of the WNT/β-catenin pathway is a key event in CRC initiation. This pathway interacts with other nuclear signaling pathways, including members of the nuclear receptor superfamily and their transcription coregulators. In this review, we provide an overview of the literature dealing with the main coactivators(NCo A-1 to 3, NCo A-6, PGC1-α, p300, CREBBP and MED1) and corepressors(N-Co R1 and 2, NRIP1 and MTA1) of nuclear receptors and summarize their links with the WNT/β-catenin signaling cascade, their expression in CRC and their role in intestinal physiopathology.

关键词： Immunohistochemistry Colon cancer Nuclear receptors Transcription coregulators WNT signaling

In vitro anti-melanoma effect of polyphenolic compounds

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Asian Pacific Journal of Tropical Biomedicine 2022年第10期12卷 446-452页

作者： Fairouz Sioud Mouna Maatouk Imen mokdad Bzeouich Leila Chekir Ghedira Soumaya Kilani-Jaziri Unit of Bioactive and Natural Substances and Biotechnology UR17ES49 Faculty of Dentistry University of MonastirAvicenne Street5019 MonastirTunisia Department of Pharmaceutical Sciences A Faculty of Pharmacy of Monastir University of MonastirIbn sina Street5000MonastirTunisia Faculty of Medecine of Monastir University of Monastir Avicenne Street5000MonastirTunisia

Objective:To evaluate the effects of phenolic acids(caffeic,ferulic,and coumaric acids)and flavones(luteolin and apigenin)on the proliferation and melanogenesis in murine melanoma B16-F10 ***:Cell proliferation was determined after 24 and 48 hours of incubation using MTT *** effects of these tested compounds on cell cycle progression were analyzed by flow ***,the melanin content and tyrosinase activity were measured spectrophotometrically at 475 ***:Luteolin and apigenin exhibited significant anti-proliferative activity against B16-F10 cells,while caffeic,ferulic,and coumaric acids induced slight inhibition after 24 and 48 hours of *** tested compounds disturbed cell cycle progression of B16-F10,by a subsequent decrease in G1 and arrested cycle progression in either G1/S or G2/M ***,apigenin provoked an increase in melanin content of B16-F10 *** contrast,luteolin,caffeic,ferulic and coumaric acids induced a decrease in melanin content of B16-F10 cells by inhibiting tyrosinase ***:These active polyphenols may be used as skin whitening agents or natural tanning agents to treat skin pigmentation disorders.

关键词： Polyphenols Cytotoxic activity Cell cycle Melanin content Tyrosinase activity Melanoma

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育龄妇女的精神、躯体抑郁症和高危行为

世界核心医学期刊文摘（妇产科学分册） 2005年第9期1卷 43-44页

作者： Ahluwalia I.B. Mack K.A. mokdad A. 王伟华 Div. of Adult and Comm unity Health Centers for Dis. Contr. and Prev. Mail-Stop K-66 4770 Buford H ighway NE Atlanta GA 30341-3724 United States Dr.

OBJECTIVE: To examine the prevalence of mental and physical distress indicat or s among women of reproductive age and the association of these indicators with c igarette smoking and alcohol use, by pregnancy status. METHODS: The Behavioral R isk Factor Surveillance System data for several years were aggregated across sta tes and weighted for this analysis. Seven measures of self-reported mental and physical distress and general health were examined along with demographic variab les. RESULTS: Overall, 6.7%(95%confidence interval [CI] 6.5-6.9) of women rep orted frequent physical distress, 12.3%(95%CI 12.0-12.6) reported frequent me ntal distress, 9.9%(95%CI 9.4-10.4) reported frequent depression, 18.4%(95% CI 17.8-19.1) reported feeling anxious, and 34.3%(95%CI 33.5-35.1) reported that they frequently did not get enough rest. At the time of the survey 4.6%of the women were pregnant. Pregnant women were less likely than nonpregnant women to report frequent mental distress. Although there was attenuation of cigarette smoking and alcohol use during pregnancy, those with mental and physical distr ess were more likely to consume cigarettes and alcohol than were those without s uch experiences. CONCLUSION: High proportions of reproductive-age women report frequent mental and physical distress. Women experiencing menial and physical di stress were more likely to report consuming cigarettes and alcohol than women wi thout such experiences.

关键词：郁症高危行为精神抑郁非妊娠妇女监测系统人口统计学变量行为风险

文献快报(7):世界范围10～24岁青少年1990—2013年间疾病负担

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中国学校卫生 2016年第7期37卷 I0001-I0001页

作者： mokdad A H FOROUZANFAR M H DAOUD F 孙莹安徽医科大学公共卫生学院儿少卫生与妇幼保健学系合肥230032

10-24岁青少年是全球发展中容易被忽略的群体。青少年群体健康模式的变化会影响未来全人群健康以及全球经济发展。由Bill—Melinda基金会赞助的全球疾病负担研究2013（Global Burden of Disease Study 2013，GBD2013），资料来自188个... 详细信息

10-24岁青少年是全球发展中容易被忽略的群体。青少年群体健康模式的变化会影响未来全人群健康以及全球经济发展。由Bill—Melinda基金会赞助的全球疾病负担研究2013（Global Burden of Disease Study 2013，GBD2013），资料来自188个国家年度评估的306种疾病和伤害，同时监测1233个健康相关结局变量和79种疾病危险因素，全景综述了青少年在1990-2013年期间现在以及预期的疾病负担，主要指标为伤残调整寿命年（disability-adjusted life—years，DALYs）。

关键词：疾病负担青少年世界范围伤残调整寿命年文献疾病危险因素人群健康经济发展

乙烯雌酚子宫特殊护理治疗可以改善患者的产科预后

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世界核心医学期刊文摘（妇产科学分册） 2005年第6期1卷 60-61页

作者： Amour M.-C. mokdad A. Mayenga J.-M. Belaisch-Allart J. 刘亦恒

Objective. - To define the interest of a specific care management of pregnancies in patients exposed in utero to diethylstilbestrol, with the intention of reducing the number of spontaneous miscarriage and prematurity. Patients and methods. - One hundred and three pregnancies in 49 patients exposed in utero to diethylstilbestrol were followed during a 4- year study, while establishing a specific care management of pregnancies in those women. Results. - Spontaneous miscarriage rate was 18.5% , among which 16.5% before 15 weeks of pregnancy and 2% after 15 weeks of pregnancy. Premature birth rate was 41.9% , among which 10.8% of great premature birth (before 32 weeks of pregnancy), 13,5% of moderate premature birth (between 32 and 36 weeks of pregnancy), and 17.6% of minor prematurity (after 36 weeks of pregnancy). The patients’ average delivery term was 36 ± 3.6 weeks. Discussion and conclusion. - As compared with the literature data, our miscarriage and prematurity rates are found to be lower. Our specific care management seems thus to be effective.

关键词：护理治疗乙烯雌酚自发性流产早产率流产率分娩时间周前

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美国的心血管健康差异状况

世界核心医学期刊文摘（心脏病学分册） 2005年第9期1卷 43-43页

作者： Mensah G.A. mokdad A.H. Ford E.S. 赵和平 Dr.Office of the Director Natl. Ctr. Chron. Dis. Prev. H. Centers for Dis. Contr. and Prev. 4770 Buford Hwy NE Atlanta GA 30341-3717 United States

Background -Reducing health disparities remains a major public health challenge in the United States. Having timely access to current data on disparities is important for policy and program development. Accordingly, we assessed the current magnitude of disparities in cardiovascular disease(CVD) and its risk factors in the United States. Methods and Results -Using national surveys, we determined CVD and risk factor prevalence and indexes of morbidity, mortality, and overall quality of life in adults ≥18 years of age by race/ethnicity, sex, education level, socioeconomic status, and geographic location. Disparities were common in all risk factors examined. In men, the highest prevalence of obesity(29.2%) was found in Mexican Americans who had completed a high school education. Black women with or without a high school education had a high prevalence of obesity(47.3%). Hypertension prevalence was high among blacks(39.8%) regardless of sex or educational status. Hypercholesterolemia was high among white and Mexican American men and white women in both groups of educational status. Ischemic heart disease and stroke were inversely related to education, income, and poverty status. Hospitalization was greater in men for total heart disease and acute myocardial infarction but greater in women for congestive heart failure and stroke. Among Medicare enrollees, congestive heart failure hospitalization was higher in blacks, Hispanics, and American Indians/Alaska Natives than among whites, and stroke hospitalization was highest in blacks. Hospitalizations for congestive heart failure and stroke were highest in the southeastern United States. Life expectancy remains higher in women than men and higher in whites than blacks by ≈5 years. CVD mortality at all ages tended to be highest in blacks. Conclusions -Disparities in CVD and related risk factors remain pervasive. The data presented here can be invaluable for policy development and in the planning, implementation, and evaluation

关键词：心血管健康住院率充血性心衰高中教育心血管疾病肥胖患病率黑人女性普查方法缺血性心脏病急性心肌梗死

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耐高温压力管道聚乙烯树脂的设计和筛选

上海塑料 2021年第6期49卷 28-33页

作者：阿卜杜哈米德·莫克达德阿兹丁·科尤海卡·希尔德布兰特马克·博拉克张寅杰沙特基础工业塑料应用中心沙特阿拉伯利雅得999088 沙特基础工业赫伦技术中心荷兰赫伦6167 沙特基础工业(中国)投资有限公司上海201319

重点开发用于工业管道应用的高密度聚乙烯,使管道达到长期使用寿命和耐热性要求,特别是目标应用于恒温40~60℃或温度峰值高达80℃时。为了满足上述应用要求,需要优化普通高密度聚乙烯管道树脂,以符合长期使用的条件。通过树脂设计和添... 详细信息

重点开发用于工业管道应用的高密度聚乙烯,使管道达到长期使用寿命和耐热性要求,特别是目标应用于恒温40~60℃或温度峰值高达80℃时。为了满足上述应用要求,需要优化普通高密度聚乙烯管道树脂,以符合长期使用的条件。通过树脂设计和添加剂选择赋予管道聚乙烯材料长期耐高温性能。利用加速的小规模测试,从添加剂的角度确定较好的解决方案,然后将其投入更大规模的生产,评估管道性能,从而选择最优方案。从树脂设计的角度来看,链缠绕密度的优化是改善管道抗慢速裂纹增长的关键,保证了管道的长期良好性能。链缠绕密度通过共聚单体类型、足够数量共聚单体的插入以及分子量分布的调整而提高。

关键词：聚乙烯管道耐热性