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Outcome ofJudet＇s quadricepsplasty for knee contractures and the effect of local infiltration of epinephrine on reducing blood loss

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Chinese Journal of Traumatology 2017年第3期20卷 147-150页

作者： Akbar Jaleel Zubairi Haroon Rashid Rizwan Haroon Rashid moiz ali Pervaiz Mehmood Hashmi Section of Orthopedics Department of Surgery Ago Khan University Hospital Karachi 74800 Pakistan Aga Khan University Medical College Karachi 74800 Pakistan

Objective： To evaluate the effectiveness ofJudet＇s quadricepsplasty for treatment of knee contractures and to identify the effect of local infiltration of epinephrine on blood loss associated with this procedure. Methods： A retrospective cohort study was conducted in which all cases of knee contractures managed with Judet＇s quadricepsplasty from 1st January 2009 to 31st December 2013 were included and were divided into two groups. The epinephrine group included patients who were infiltrated with diluted epinephrine （1：400,000） along with xylocaine, around the operative field 15 min prior to the incision time, while the control group did not receive any infiltration. Judet＇s outcome, blood loss, drop in he- moglobin and required blood transfusion were noted for all patients and compared between both groups. Results： Most common preceding pathology identified for the development of knee contractures was periarticular fracture while ilizarov application was the most common etiology. Both groups were found similar in all preoperative characteristics except preoperative flexion contracture （p = 0.02）. All func- tional outcome measures including Judet＇s outcome were similar in both groups. In contrast, duration of surgery （p = 0.01）, blood loss （p = 0.02）, drop in hemoglobin （p = 0.01） and number of transfusions （p = 0.03） were significantly reduced in epinephrine group. Conclusion： Judet＇s quadricepsplasty is a useful procedure to increase the range of motion of rigid knees and local infiltration of epinephrine is effective in decreasing the amount of subsequent blood loss and transfusion requirements.

关键词： Knee contracture Blood transfusion Epinephrine Knee range of motion Operative time

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Impact of non-alcoholic fatty liver disease on coronavirus disease 2019: A systematic review

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World Journal of Hepatology 2024年第8期16卷 1185-1198页

作者： Abdul Moeed Muhammad Omar Larik Muhammad Ahmed ali Fahim Hafsah alim Ur Rahman Lubna Najmi Mah I Kan Changez Muhammad moiz Javed Md Al Hasibuzzaman Department of Internal Medicine Dow University of Health SciencesKarachi 74200SindhPakistan Department of Internal Medicine Dow International Medical CollegeKarachi 74200SindhPakistan Department of Internal Medicine Ziauddin UniversityKarachi 75000SindhPakistan Department of Research Yale UniversityNew Haven 06520CTUnited States Department of Internal Medicine King Edward Medical UniversityLahore 54000PunjabPakistan Institute of Nutrition and Food Science University of DhakaDhaka 1000Bangladesh Department of Medicine The Affiliated Hospital of Medical School of Ningbo UniversityNingbo 315211Zhejiang ProvinceChina

BACKGROUND Many studies have revealed a link between non-alcoholic fatty liver disease(NA-FLD)and coronavirus disease 2019(COVID-19),making understanding the relationship between these two conditions an absolute *** To provide a qualitative synthesis on the currently present data evaluating COVID-19 and *** This systematic review was conducted in accordance with the guidelines pro-vided by preferred reporting items for systematic reviews and meta-analyses and the questionnaire utilized the population,intervention,comparison,and outcome *** search strategy was run on three separate databases,PubMed/MEDLINE,Scopus,and Cochrane Central,which were systematically searched from inception until March 2024 to select all relevant *** addition,***,***,and Google Scholar were searched to identify grey *** After retrieval of 11 studies,a total of 39282 patients data were *** was found in 11.5%and 9.4%of people in NAFLD and non-NAFLD *** all,23.2%of NAFLD patients and 22%of non-NAFLD admissions diagnosed with COVID-19 were admitted to the intensive care unit,with days of stay *** support ranged from 5%to 40.5%in the NAFLD cohort and from 3.1%to 20%in the non-NAFLD *** incidence of acute liver injury showed *** improvement on days 7 and 14 between the two classifications was *** stay ranged from 9.6 days to 18.8 days and 7.3 days to 16.4 days in the aforementioned cohorts respectively,with 73.3%and 76.3%of patients being *** rates *** Clinical outcomes except mortality consistently showed a worsening trend in patients with NAFLD and concomitant *** research in conducting prospective longitudinal studies is essential for a more powerful conclusion.

关键词： Non-alcoholic fatty liver disease Coronavirus disease 2019 Mechanical ventilation Intensive care unit Acute liver injury

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