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Anti-inflammatory, anti-oxidative and anti-apoptotic effects of Heracleum persicum L. extract on rats with gentamicin-induced nephrotoxicity

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Asian Pacific Journal of Tropical Biomedicine 2021年第2期11卷 47-58页

作者： mohsen Akbaribazm Nader Goodarzi mohsen Rahimi Leila Naseri Mozafar Khazaei Students Research Committee Kermanshah University of Medical SciencesKermanshahIran Department of Basic Sciences and Pathobiology Faculty of Veterinary MedicineRazi UniversityKermanshahIran Department of Medical Parasitology and Mycology School of MedicineShahid Beheshti University of Medical SciencesTehranIran Fertility and Infertility Research Center Health Technology InstituteKermanshah University of Medical SciencesKermanshahIran

Objective:To evaluate the effect of Heracleum persicum *** gentamicin-induced nephrotoxicity in ***:Thirty-six Wistar rats were divided into 6 groups including control(normal saline),gentamicin(80 mg/kg/d for 10 d),Heracleum persicum(750 mg/kg/d),and gentamicin(10 d)+Heracleum persicum extract at three different doses(250,500,and 750 mg/kg/d for 40 d).Urine creatinine,urea,protein,and albumin levels were *** addition,serum urea,creatinine,sodium,potassium,cytokines(TNF-α,IL-1β,IL-6,and IL-10),glutathione peroxidase activity,total antioxidant capacity,kidney malondialdehyde,stereological parameters,and expressions of apoptosis-related genes(p53,Bax,Bcl-2,and caspase-3)were *** LD50 of Heracleum persicum extract was determined based on Lorke’s *** evaluation was also ***:In addition to decreased urine protein and albumin,and increased creatinine and urea,co-treatment with gentamicin and Heracleum persicum significantly reduced levels of creatinine and urea,and increased sodium and potassium in *** persicum treatment also improved stereological parameters and serum inflammatory *** was a significant increase in serum glutathione peroxidase activity and total antioxidant capacity as well as a reduction in malondialdehyde ***,treatment with Heracleum persicum extracts downregulated p53,caspase-3,and Bax and upregulated Bcl-2 *** histopathological evaluation,Heracleum persicum extracts showed protection against gentamicin-induced renal ***:Heracleum persicum exhibits protective effects against gentamicin-induced structural and functional renal impairments.

关键词： Kidney Heracleum persicum L. Gentamicin Stereology Apoptosis

A new boundary element solution to evaluate the geometric effects of the canyon site on the displacement response spectrum

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Earthquake Engineering and Engineering Vibration 2019年第2期18卷 267-284页

作者： Reza Tarinejad mohsen Isari Abbasali Taghavi Ghalesari Department of Civil Engineering University of Tabriz Department of Civil Engineering The University of Texas at El Paso 500 W University Ave.

This paper presents a step-by-step procedure using the three-dimensional boundary element approach to study the behavior of semi-circular canyons under seismic shear waves. The boundary element code TDASC allows utilization for various canyon geometries, evaluation of concurrent seismic waves and calculation of the ground motions on canyons due to an excitation at any arbitrary point of the incident field. Considering the widening ratio of the canyon(including prismatic, semi-prismatic and non-prismatic canyons), wave characteristics(wavelength, dimensionless period, direction) and maximum amplification pattern, the solution was applied to carry out a series of parametric studies. It was shown that canyon form can significantly affect the displacement amplification, especially at the points located on its edges. By increasing the wave dimensionless frequency(η > 1), the amplification pattern becomes more complex. On the basis of the results from a variety of considered cases, a new expression has been presented for the limiting wavelength beyond which the widening of the canyon will not have a major effect on the displacement amplification. To verify the reliability of the proposed approach, the obtained results, expressed in terms of displacement amplitude, were compared with those from the available published literature and a reasonably good agreement was observed.

关键词： canyon boundary element method widening ratio site effect wave scattering amplifi cation

On the Relation Between Symmetry of Radio Galaxies and Their Physical Parameters

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Research in Astronomy and Astrophysics 2024年第9期24卷 37-59页

作者： mohsen Javaherian Halime Miraghaei Hooman Moradpour Research Institute for Astronomy and Astrophysics of Maragha(RIAAM) University of MaraghehP.O.Box 55136-553MaraghehIran

Gravity as a fundamental force plays a dominant role in the formation and evolution of cosmic objects and leaves its effect in the emergence of symmetric and asymmetric ***,analyzing the symmetry criteria allows us to uncover mechanisms behind the gravity interaction and understand the underlying physical processes that contribute to the formation of large-scale structures such as *** use a segmentation process using intensity thresholding and the k-means clustering algorithm to analyze radio galaxy *** employ a symmetry criterion and explore the relation between morphological symmetry in radio maps and host galaxy *** properties(stellar mass,black hole mass,optical size(R_(50)),concentration,stellar mass surface density(μ_(50)),and stellar age)and radio properties(radio flux density,radio luminosity,and radio size)are *** found that there is a correlation between symmetry and radio size,indicating larger radio sources have smaller symmetry ***,size of radio sources should be considered in any investigation of *** correlations are also observed with other properties,such as R_(50)for FRI galaxies and stellar *** compare the symmetry differences between FRI and FRII radio *** galaxies show higher symmetry in 1.4 GHz and 150 MHz *** the influence of radio source sizes,we discovered that this result is independent of the sizes of radio *** findings contribute to our understanding of the morphological properties and analyses of radio galaxies.

关键词： methods:data analysis techniques:image processing catalogs galaxies:nuclei galaxies:distances and redshifts

Selecting proper sites for underground dam construction using Multi-Attribute Utility Theory in arid and semi-arid regions

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Journal of Mountain Science 2023年第1期20卷 197-208页

作者： Mohammad hassan SADEGHIRAVESH hassan KHOSRAVI Azam ABOLHASANI Department of Environment College of AgricultureTakestan BranchIslamic Azad UniversityTakestanIran Department of Reclamation of Arid and Mountainous Regions Faculty of Natural ResourcesUniversity of TehranTehranIran

Although the construction of underground dams is one of the best methods to conserve water resources in arid and semi-arid regions,applying efficient methods for the selection of suitable sites for subsurface dam construction remains a *** to the costly and time-consuming methods of site selection for underground dam construction,this study aimed to present a new method using geographic information systems techniques and decision-making *** exclusionary criteria including fault,slope,hypsometry,land use,soil,stream,geology,and chemical properties of groundwater were selected for site selection of dam construction and inappropriate regions were omitted by integration and scoring layers in ArcGIS based on the Boolean ***,appropriate sites were prioritized using the Multi-Attribute Utility *** to the results of the utility coefficient,seven sites were selected as the region for underground dam construction based on all criteria and experts’*** site of Nazarabad dam was the best location for underground dam construction with a utility coefficient of 0.7137 followed by sites of Akhavan with a utility coefficient of 0.4633 and Mirshamsi with a utility coefficient of *** study proposed a new approach for the construction of the subsurface dam at the proper site and help managers and decision-makers achieve sustainable water resources with limited facilities and capital and avoid wasting national capital.

关键词： Prioritization Geographic information system Multi-Attribute decision making Arid region

Gastrointestinal viral shedding in children with SARS‑CoV‑2:a systematic review and meta‑analysis

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World Journal of Pediatrics 2022年第9期18卷 582-588页

作者： Sepideh Benvari Shima Mahmoudi mohsen Mohammadi Department of Microbiology Faculty of MedicineQazvin University of Medical SciencesQazvinIran Pediatric Infectious Disease Research Center Tehran University of Medical SciencesTehranIran Non-Communicable Pediatric Diseases Research Center Health Research InstituteBabol University of Medical SciencesBabolIran

Background Coronavirus disease 2019(COVID-19)has diferent manifestations in pediatric *** is assumed that they might present more gastrointestinal symptoms with a diferent viral shedding pattern in gastrointestinal *** this systematic review and meta-analysis,we aimed to evaluate the viral shedding pattern in gastrointestinal specimens of children with *** We searched all published studies in English language in PubMed,Web of Science,and Scopus,up to date as of October *** search included the term"severe acute respiratory syndrome coronavirus 2,COVID-19,SARS-CoV-2,novel coronavirus,or coronavirus;and shed,excrete,secret,or carriage;and stool or rectal;and children or pediatrics".We included studies evaluating SARS-CoV-2 shedding in gastrointestinal specimens,including rectal swabs and stool samples of children with COVID-19 *** excluded duplicated data,case reports,and studies without original *** Twelve studies met the eligibility criteria for the qualitative synthesis,10 of which were included in the *** pooled prevalence of gastrointestinal severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)RNA in children with COVID-19 was 86%(95%confdence interval 73%–96%,I 2=62.28%).After respiratory specimen had become negative,72%(43/60)had persistent shedding in gastrointestinal *** gastrointestinal RNA had a positive test result for more than 70 days after symptoms *** Gastrointestinal shedding of SARS-CoV-2 might occur in a substantial portion of children and might persist long after negative respiratory *** research is recommended to fnd the role of SARS-CoV-2 gastrointestinal shedding in transmission in children.

关键词： Coronavirus disease 2019(COVID-19) Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) Viral shedding

The Hochschild Cohomology of the Chinese Monoid Algebra

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Algebra Colloquium 2022年第4期29卷 619-632页

作者： hassan Alhussein Siberian State University of Telecommunications and Informatics NovosibirskRussia Novosibirsk State University of Economics and ManagementNovosibirskRussia

In this work we find the groups of Hochschild cohomologies for the Chinese monoid algebra and derive its Hilbert and Poincaré*** order to obtain this result we construct the Anick resolution via the algebraic discret... 详细信息

关键词： Hochschild cohomology Anick resolution Grobner-Shirshov basis Morse matching

Density,refractive index and liquid–liquid equilibrium data of polyethylene glycol 3000 + potassium formate + water at different pH values

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Chinese Journal of Chemical Engineering 2018年第1期26卷 168-174页

作者： Fatemeh Ahmadi mohsen Pirdashti Abbas Ali Rostami Chemical Engineering Department Faculty of EngineeringShomal University

New liquid-liquid equilibrium data for polyethylene glycol （PEG） 3000 ＋ CHO2K ＋ H20 systems were measured at 298.15 K and pH values of 7.95, 8.40 and 9.98. It was found that an increase in pH caused the binodal curve to be displaced downward and the two-phase region to expand. Accordingly, the binodal curve was adjusted to the Pirdashti equation and the tie-line compositions were correlated using the Othmer-Tobias, Bancroft and Hand equations. The study measured the refractive index and densities of several homogeneous binary and ternary solutions. The solutions were used for calibration within a range of 0% to 30% of the mass of the PEG and potassium formate. The density and refractive index data show a linear variation with the mass fraction of the polymer and the salt. The effect of pH on the binodal, tie-line lengths （TLL） and slope of the tie-line （STL） in the systems was exam- ined. It was found that an increase in pH increased the TLL and decreased the STL It was observed that the density of the aqueous two-phase system was influenced by the TLL The difference in density between phases （△p） increased as the TLL and pH increased. It was found that the TLL and Ap showed a linear relationship. The effective excluded volume （EEV） of the PEG was obtained and it was found that EEV also increased as the pH increased.

关键词： Liquid-liquid equilibrium data Density Polyethylene glycol Potassium formate

The bulk viscous string cosmology in an anisotropic universe with late time acceleration

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Research in Astronomy and Astrophysics 2013年第4期13卷 387-398页

作者： hassan Amirhashchi Department of Physics Mahshahr BranchIslamic Azad University

A model of a cloud formed by massive strings is used as a source of Bianchi type II cases. We assume that the expansion （θ） in the model is proportional to the shear （σ）. To get an exact solution, we consider the equation of state of the fluid to be in the stiff form. It is found that the bulk viscosity played a very important role in the history of the universe. In the presence of bulk viscosity the particles dominate over strings whereas in the absence of it, strings dominate over the particles, which is not consistent with recent observations. Also we observe that the viscosity causes the expansion of the universe to be accelerating. Our models are evolving from an early decelerating phase to a late time accelerating phase. The physical and geometrical behaviors of these models are discussed.

关键词： cosmology: theory -- viscous fluid -- massive string

Microstructural characteristics and mechanical properties of Al-2024 alloy processed via a rheocasting route

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International Journal of Minerals,Metallurgy and Materials 2015年第1期22卷 59-67页

作者： Behnam Rahimi Hamed Khosravi mohsen Haddad-Sabzevar Department of Metallurgy and Materials Engineering Faculty of EngineeringFerdowsi University of Mashhad Faculty of Materials Science and Engineering K.N.Toosi University of Technology

This article reports the effects of stirring speed and T6 heat treatment on the microstructure and mechanical properties of Al-2024 alloy synthesized by a rheocasting process. There was a decrease in grain size ofα-Al particles corresponding to an increase in stirring speed. By increasing the stirring speed, however, the globularity of matrix particles first increased and then declined. It was also found that the hardness, compressive strength, and compressive strain increased with the increase of stirring speed. Microstructural studies revealed the presence of nonsoluble Al15（CuFeMn）3Si2 phase in the vicinity of CuAl2 in the rheocast samples. The required time for the solution treatment stage was also influenced by stirring speed;the solution treatment time decreased with the increase in stirring speed. Furthermore, the rheo-cast samples required a longer homogenization period compared to conventionally wrought alloys. Improvements in hardness and compres-sive properties were observed after T6 heat treatment.

关键词： aluminum alloys rheocasting microstructure mechanical properties